No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Colostroplex Ingredients & Drug Interactions

by Health Concerns

Tablet Or Pill Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

Colostroplex is a dietary supplement by Health Concerns with 1 active ingredient. Its ingredients are commonly taken for immune support, gut health and digestion, exercise recovery.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Colostroplex by Health Concerns

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 1 active ingredient.
  • “Proprietary Blend (Non-Nutrient/Non-Botanical)” is a proprietary blend — the label gives one combined amount (500 mg) without saying how much of each component you get.

Colostroplex contains one active ingredient: bovine colostrum, which is a nutrient-rich fluid produced by cows in the first few days after birth. It's rich in antibodies and growth factors that may help support immune function and gut health.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Immune support and gut health.
  • We looked for evidence on: Athletic performance, Chemotherapy-related infection, Child growth, Critical illness (trauma), Exercise-induced respiratory infections, Graft-versus-host disease (GVHD) — and 4 related terms.
  • The strongest evidence on file: Bovine Colostrum is rated "Possibly Effective" for HIV/AIDS-related diarrhea (Natural Medicines).
  • Also on file: Bovine Colostrum is rated "Possibly Effective" for Exercise-induced respiratory infections.
  • Also on file: Bovine Colostrum is rated "Insufficient Reliable Evidence To Rate" for Athletic performance, Chemotherapy-related infection, Critical illness (trauma), Influenza, and more.

Bovine colostrum is possibly effective for HIV/AIDS-related diarrhea, rotaviral diarrhea, and exercise-induced respiratory infections, according to the evidence we hold. It's rated possibly ineffective for necrotizing enterocolitis (a serious bowel condition in newborns).

For other uses, effectiveness data isn't established in what we have on file.

The evidence, ingredient by ingredient Bovine Colostrum

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Bovine colostrum is generally well tolerated in most adults. However, if you have a milk or dairy allergy, you should avoid it.

A small number of trial participants reported mild bloating, nausea, diarrhea, and unsettled stomach at rates similar to those in a whey-based control group. In people with HIV-related infections, it has occasionally caused nausea, vomiting, elevated liver function tests, and decreased blood counts — so if you fall into that category, check with your doctor first.

There isn't enough reliable safety data for pregnancy, and safety during breastfeeding is not well studied — talk with your doctor or pharmacist before using it in either situation.

Side effects, ingredient by ingredient Bovine Colostrum

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredient we could check. Always run your exact medications through the interaction checker below before you start, just to be sure.

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

Colostroplex may be worth considering if you're dealing with certain types of diarrhea or exercise-related respiratory infections and want an immune-support option. If you have a dairy allergy, skip it.

If you're pregnant, breastfeeding, or have HIV-related illness, check with your doctor first — the safety data isn't solid enough to go it alone.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated May 24, 2017.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Colostroplex, straight from the product label.

Brand Health Concerns
Net contents 60 Tablet(s)
Market status On market
Date entered into DSLD May 24, 2017
DSLD ID 72820
Product type Non-nutrient/non-botanical
Supplement form Tablet Or Pill
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Colostroplex by Health Concerns, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
4 Tablet(s)
Servings per container
60
IngredientAmount% DV
Proprietary Blend (Non-Nutrient/Non-Botanical)500 mg--
Bovine Colostrum0 NP--

Other ingredients: Vegetable Gum, Silicon Dioxide, Stearic Acid, Pharmaceutical Glaze

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: One to four tablets per day between meals.

Formula

Notice: This product contains trace amounts of milk.

Bovine Colostrum

Precautions

Notice: This product contains trace amounts of milk.

This product is not intended for use by pregnant women.

Brand IP Statement(s)

Energetic formulas

Combining modern research and ancient wisdom

FDA Statement of Identity

Dietary Supplement

General Statements

Made in the U.S.A.

See for yourself

Colostroplex by Health Concerns label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Colostroplex by Health Concerns

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container60 Amounts shown are per serving.

Proprietary Blend (Non-Nutrient/Non-Botanical)

500 mg per serving

Other (inactive) ingredients: Vegetable Gum, Silicon Dioxide, Stearic Acid, Pharmaceutical Glaze. These complete the product’s ingredient list but are not active constituents.

Interaction report

Colostroplex by Health Concerns Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Colostroplex. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Colostroplex, from the product label.

Health Concerns

See all Health Concerns products
Name
Health Concerns
Street Address
8001 Capwell Drive
City
Oakland
State
CA
ZipCode
94621
Phone Number
(800) 233-9355
Web Address
www.healthconcerns.com/pro
Pharmacist Counseling Corner

Colostroplex by Health Concerns: Common Questions

Does Colostroplex by Health Concerns interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Colostroplex. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Colostroplex contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is bovine colostrum the same as regular cow's milk?
No — bovine colostrum is the nutrient-rich fluid cows produce in the first few days after giving birth. It's much higher in antibodies and growth factors than regular milk, which is why it's used as a supplement.
Can I take this if I have a milk allergy?
No, you should avoid it. Bovine colostrum comes from milk and can trigger a reaction in people with a dairy allergy.
What side effects might I notice?
Most people tolerate it well. Some trial participants reported mild bloating, nausea, diarrhea, or an unsettled stomach, but these were rare and mild.
Is it safe to take while pregnant or breastfeeding?
There isn't enough reliable safety data for pregnancy, and safety during breastfeeding is not well studied. Talk with your doctor or pharmacist for personalized advice before using it.
Does it actually work for diarrhea?
Bovine colostrum is possibly effective for HIV/AIDS-related diarrhea and rotaviral diarrhea. That means there's some promising evidence, but it's not a sure thing — talk to your doctor about whether it makes sense for your situation.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Colostroplex is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Colostroplex label
Go deeper

The Full Monographs Behind Colostroplex’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Colostroplex's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 8 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Bovine Colostrum 8 references
  1. Lewis CJ. Letter to reiterate certain public health and safety concerns to firms manufacturing or importing dietary supplements that contain specific bovine tissues. FDA. Available at: www.cfsan.fda.gov/~dms/dspltr05.html.
  2. Greenberg PD, Cello JP. Treatment of severe diarrhea caused by Cryptosporidium parvum with oral bovine immunoglobulin concentrate in patients with AIDS. J Acquir Immune Defic Syndr Hum Retrovirol 1996;13:348-54. PubMed
  3. Duff WR, Chilibeck PD, Rooke JJ, Kaviani M, Krentz JR, Haines DM. The effect of bovine colostrum supplementation in older adults during resistance training. Int J Sport Nutr Exerc Metab. 2014 Jun;24(3):276-85. PubMed
  4. Sanctuary MR, Kain JN, Chen SY, et al. Pilot study of probiotic/colostrum supplementation on gut function in children with autism and gastrointestinal symptoms. PLoS One. 2019;14(1):e0210064. PubMed
  5. Porcaro F, Caminiti L, Crisafulli G, Guglielmo F, Pajno GB. Anaphylaxis to cutaneous exposure to bovine colostrum based cream. Asian Pac J Allergy Immunol. 2019;37(1):9-11.
  6. Yan X, Pan X, Ding L, et al. Bovine colostrum to supplement the first feeding of very preterm infants: The PreColos randomized controlled trial. Clin Nutr 2023;42(8):1408-1417. PubMed
  7. Halasa M, Skonieczna-Zydecka K, Machalinski B, Bühner L, Baskiewicz-Halasa M. Six Weeks of Supplementation with Bovine Colostrum Effectively Reduces URTIs Symptoms Frequency and Gravity for Up to 20 Weeks in Pre-School Children. Nutrients 2023;15(16):3626 PubMed
  8. Simonsen MB, Kappel SS, Aunsholt L, Möller S, Sangild PT, Zachariassen G. Mineral supplementation for very preterm infants fed fortified human milk. J Pediatr Gastroenterol Nutr 2024;78(6):1389-1397. PubMed

See these in context on the Bovine Colostrum monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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