Performance Probiotic Natural Acai Flavor Ingredients & Drug Interactions
by AIVIA
What is this page for?
First and foremost: checking Performance Probiotic Natural Acai Flavor against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Performance Probiotic Natural Acai Flavor is a dietary supplement by AIVIA with 6 active ingredients. Its ingredients are commonly taken for constipation, diarrhea, high cholesterol.Based on those ingredients, 2,083 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Dietary Fiber, Bacillus subtilis DE-111. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Performance Probiotic Natural Acai Flavor by AIVIA
Ask about any prescription or over-the-counter medication and we check it for interactions with Performance Probiotic Natural Acai Flavor by AIVIA — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Performance Probiotic Natural Acai Flavor by AIVIA
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
This powder contains five active ingredients: two enzymes (Serratiopeptidase and ProHydrolase), a proprietary probiotic blend containing three live bacterial strains (Bifidobacterium animalis lactis, Lactobacillus rhamnosus, and Bacillus subtilis), and prebiotic fiber (inulin and fructooligosaccharides) to feed the beneficial bacteria. The inactive ingredients include acai flavor, a sunflower oil creamer, citric acid, and stevia to sweeten it.
Does it work?
Strong evidence
For Bacillus subtilis specifically, the data shows it's possibly effective for antibiotic-associated diarrhea (diarrhea that comes on after you've taken antibiotics). For athletic performance, constipation, eczema, diabetes, and cirrhosis, the evidence isn't strong enough yet to rate whether it works.
We don't have effectiveness ratings on file for the other active ingredients in this product.
How safe is it?
Well-documented data
Bacillus subtilis is generally well tolerated in healthy adults, though the product facts note that quality and safety can vary by strain and brand. One person in a trial reported a headache, and diarrhea has been reported rarely.
The safety data is limited, so it's best to talk with your doctor before starting — especially if you're older, have diabetes, kidney problems, or a weakened immune system, since there are rare documented cases of serious Bacillus subtilis infection in those groups. No pregnancy or breastfeeding safety data is on file for this product.
Meds to double-check
Moderate interaction found
If you're on antibiotic drugs, take them at a different time than this probiotic — they can interfere with each other. Since we couldn't check interaction data for several ingredients in this product, run your full medication list through the checker below before you start.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This probiotic may help if you're dealing with diarrhea after antibiotics. If you're healthy and want to try it, space it apart from any antibiotic course.
If you have a weakened immune system, diabetes, or kidney issues, check with your doctor first. Your pharmacist can help you time it right with your other medications.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 25, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Performance Probiotic Natural Acai Flavor, straight from the product label.
| Brand | AIVIA |
|---|---|
| Net contents | 30 Stick Pack(s); 75 Gram(s); 2.65 Ounce(s) |
| Market status | On market |
| Date entered into DSLD | Jul 25, 2024 |
| DSLD ID | 313182 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Powder |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegetarian, Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Performance Probiotic Natural Acai Flavor by AIVIA, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Calories | 10 Calorie(s) | -- |
| Total Carbohydrates | 2 Gram(s) | 1% |
| Serratiopeptidase | 0 NP | -- |
| Dietary Fiber | 1 Gram(s) | 4% |
| ProHydrolase | 0 NP | -- |
| Proprietary Probiotic Blend | 0 NP | -- |
| Bifidobacterium animalis lactis | 0 NP | -- |
| Lactobacillus rhamnosus | 0 NP | -- |
| Bacillus subtilis DE-111 | 0 NP | -- |
| Proprietary Enzyme Blend | 0 NP | -- |
Other ingredients: Fructooligosaccharides, Sunflower Oil Creamer, natural Acai Flavor, Inulin, Probiotic Blend, Citric Acid, Silicon Dioxide, Steviol Glycosides
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
Performance probiotic + Core power enzymes
More than just gut health, AIVIA Probiotic was formulated to boost performance. When combined with proper diet and exercise, the blends of clinically-studied probiotics and enzymes strengthen your core from deep within for better exercise performance, recovery, and body composition.
General Statements
30 Stick Packs (2.5g each/0.09 oz.)
The guts to win
Powered by Nature's Sunshine We are committed to you and our planet. Scan to learn more. Please recycle this carton.
FDA Statement of Identity
Dietary Supplement
Formulation
Non GMO
100% Vegetarian
Optimize your results and enhance your active lifestyle with AIVIA Probiotic.
No added sugars
Benefits Supports exercise recovery Helps optimize body composition Supports strength training results Supports normal fat metabolism Supports healthy joints and muscles
Precautions
Contains milk, soy, wheat
Keep out of reach of children.
Suggested/Recommended/Usage/Directions
Directions: Pour contents of one packet directly into mouth.
Storage
Store in a cool, dry place.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Brand IP Statement(s)
AIVIA Active nutrition
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Performance Probiotic Natural Acai Flavor by AIVIA label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Performance Probiotic Natural Acai Flavor by AIVIA
These are the 6 active ingredients this product is made of. Select any to open its full monograph.
Serving size2.5 Gram(s) Dosage formPowder Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Dietary Fiber
Interacts with2,025 drugs
Black psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. I...
Dietary Fiber monograph & interactionsProprietary Probiotic Blend
- › Bifidobacterium animalis lactis
- › Lactobacillus rhamnosus
- › Bacillus subtilis DE-111
Proprietary Enzyme Blend
- › Serratiopeptidase
- › ProHydrolase
Other (inactive) ingredients: Fructooligosaccharides, Sunflower Oil Creamer, Natural Acai Flavor, Inulin, Probiotic Blend, Citric Acid, Silicon Dioxide, Steviol Glycosides. These complete the product’s ingredient list but are not active constituents.
Performance Probiotic Natural Acai Flavor by AIVIA Drug Interactions
HelloPharmacist Interaction Report
AIVIA Performance Probiotic Natural Acai Flavor contains Bacillus subtilis, a probiotic strain with one documented interaction: taking it at the same time as antibiotic drugs (Moderate severity) may reduce how well the probiotic works.
Because antibiotics can kill the live organisms in the product, it's best to separate when you take them — ask your pharmacist for a dosing schedule that spaces them apart.
Read the full breakdown — every affected drug type, severity by severity
The product also contains Serratiopeptidase, ProHydrolase, Bifidobacterium animalis lactis, and Lactobacillus rhamnosus; we hold no interaction data for these ingredients and weren't able to check them against medications. Altogether, these interactions span 182 individual medications.
Before you start, run your current medications through the interaction checker on this page — especially any antibiotics you're taking.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Performance Probiotic Natural Acai Flavor?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Performance Probiotic Natural Acai Flavor interact with 2,083 drugs. Click any drug to see the details.
2 of the 6 ingredients in Performance Probiotic Natural Acai Flavor interact with drugs. Each result below shows which ingredient is responsible. Dietary Fiber Bacillus subtilis DE-111
Alogliptin, MetforminKazano
How Alogliptin, Metformin interacts with Performance Probiotic Natural Acai Flavor — through 1 ingredient. Tap an ingredient for the detail:
Dietary FiberOral Drugs, Metformin (glucophage) Moderate
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Alogliptin, Metformin interactionAmikacinAmikin, Arikayce
How Amikacin interacts with Performance Probiotic Natural Acai Flavor — through 2 ingredients. Tap an ingredient for the detail:
Bacillus Subtilis De-111Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B.
Read the full Bacillus Subtilis De-111 + Amikacin interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Amikacin interactionAmoxicillinAmix, Amoram, Amoxident, Amoxil Capsules, Amoxil Injection, Galenamox +3 more
How Amoxicillin interacts with Performance Probiotic Natural Acai Flavor — through 2 ingredients. Tap an ingredient for the detail:
Bacillus Subtilis De-111Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B.
Read the full Bacillus Subtilis De-111 + Amoxicillin interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Amoxicillin interactionAmoxicillin VeterinaryBiomox
How Amoxicillin Veterinary interacts with Performance Probiotic Natural Acai Flavor — through 2 ingredients. Tap an ingredient for the detail:
Bacillus Subtilis De-111Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B.
Read the full Bacillus Subtilis De-111 + Amoxicillin Veterinary interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Amoxicillin Veterinary interactionAmoxicillin, Clavulanate PotassiumAugmentin, Augmentin '125/31 SF', Augmentin '250/62 SF', Augmentin XR, Augmentin-Duo 400/57, Clavulin
How Amoxicillin, Clavulanate Potassium interacts with Performance Probiotic Natural Acai Flavor — through 2 ingredients. Tap an ingredient for the detail:
Bacillus Subtilis De-111Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B.
Read the full Bacillus Subtilis De-111 + Amoxicillin, Clavulanate Potassium interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Amoxicillin, Clavulanate Potassium interactionAmoxicillin, Omeprazole Magnesium, RifabutinTalicia
How Amoxicillin, Omeprazole Magnesium, Rifabutin interacts with Performance Probiotic Natural Acai Flavor — through 2 ingredients. Tap an ingredient for the detail:
Bacillus Subtilis De-111Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B.
Read the full Bacillus Subtilis De-111 + Amoxicillin, Omeprazole Magnesium, Rifabutin interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Amoxicillin, Omeprazole Magnesium, Rifabutin interactionAmphotericin, TetracyclineMysteclin-F
How Amphotericin, Tetracycline interacts with Performance Probiotic Natural Acai Flavor — through 2 ingredients. Tap an ingredient for the detail:
Bacillus Subtilis De-111Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B.
Read the full Bacillus Subtilis De-111 + Amphotericin, Tetracycline interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Amphotericin, Tetracycline interactionAmpicillinOmnipen, Omnipen-N, Penbritin, Principen, Rimacillin
How Ampicillin interacts with Performance Probiotic Natural Acai Flavor — through 2 ingredients. Tap an ingredient for the detail:
Bacillus Subtilis De-111Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B.
Read the full Bacillus Subtilis De-111 + Ampicillin interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Ampicillin interactionAmpicillin, SulbactamUnasyn
How Ampicillin, Sulbactam interacts with Performance Probiotic Natural Acai Flavor — through 1 ingredient. Tap an ingredient for the detail:
Bacillus Subtilis De-111Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B.
Read the full Bacillus Subtilis De-111 + Ampicillin, Sulbactam interactionAvibactam Sodium, CeftazidimeAvycaz
How Avibactam Sodium, Ceftazidime interacts with Performance Probiotic Natural Acai Flavor — through 1 ingredient. Tap an ingredient for the detail:
Bacillus Subtilis De-111Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B.
Read the full Bacillus Subtilis De-111 + Avibactam Sodium, Ceftazidime interactionAzithromycinAzasite, Zithromax, Zmax
How Azithromycin interacts with Performance Probiotic Natural Acai Flavor — through 2 ingredients. Tap an ingredient for the detail:
Bacillus Subtilis De-111Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B.
Read the full Bacillus Subtilis De-111 + Azithromycin interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Azithromycin interactionAztreonamAzactam
How Aztreonam interacts with Performance Probiotic Natural Acai Flavor — through 1 ingredient. Tap an ingredient for the detail:
Bacillus Subtilis De-111Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B.
Read the full Bacillus Subtilis De-111 + Aztreonam interactionBacampicillinPenglobe
How Bacampicillin interacts with Performance Probiotic Natural Acai Flavor — through 2 ingredients. Tap an ingredient for the detail:
Bacillus Subtilis De-111Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B.
Read the full Bacillus Subtilis De-111 + Bacampicillin interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Bacampicillin interactionBacitracinBaci-IM, Baciguent, Bacitracin Ointment
How Bacitracin interacts with Performance Probiotic Natural Acai Flavor — through 1 ingredient. Tap an ingredient for the detail:
Bacillus Subtilis De-111Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B.
Read the full Bacillus Subtilis De-111 + Bacitracin interactionBenznidazoleBenznidazole
How Benznidazole interacts with Performance Probiotic Natural Acai Flavor — through 2 ingredients. Tap an ingredient for the detail:
Bacillus Subtilis De-111Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B.
Read the full Bacillus Subtilis De-111 + Benznidazole interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Benznidazole interactionBismuth Subsalicylate, Metronidazole, TetracyclineHelidac
How Bismuth Subsalicylate, Metronidazole, Tetracycline interacts with Performance Probiotic Natural Acai Flavor — through 2 ingredients. Tap an ingredient for the detail:
Bacillus Subtilis De-111Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B.
Read the full Bacillus Subtilis De-111 + Bismuth Subsalicylate, Metronidazole, Tetracycline interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Bismuth Subsalicylate, Metronidazole, Tetracycline interactionCanagliflozin, MetforminInvokamet
How Canagliflozin, Metformin interacts with Performance Probiotic Natural Acai Flavor — through 1 ingredient. Tap an ingredient for the detail:
Dietary FiberOral Drugs, Metformin (glucophage) Moderate
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Canagliflozin, Metformin interactionCanagliflozin, Metformin HydrochlorideInvokamet XR
How Canagliflozin, Metformin Hydrochloride interacts with Performance Probiotic Natural Acai Flavor — through 1 ingredient. Tap an ingredient for the detail:
Dietary FiberMetformin (glucophage), Oral Drugs Moderate
Interaction Summary
Theoretically, black psyllium might increase the therapeutic and adverse effects of metformin.
Read the full Dietary Fiber + Canagliflozin, Metformin Hydrochloride interactionCapreomycinCapastat
How Capreomycin interacts with Performance Probiotic Natural Acai Flavor — through 1 ingredient. Tap an ingredient for the detail:
Bacillus Subtilis De-111Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B.
Read the full Bacillus Subtilis De-111 + Capreomycin interactionCarbamazepineCarbatrol, Carnexiv, Equetro, Tegretol, Tegretol XR
How Carbamazepine interacts with Performance Probiotic Natural Acai Flavor — through 1 ingredient. Tap an ingredient for the detail:
Dietary FiberCarbamazepine (tegretol), Oral Drugs Moderate
Interaction Summary
Theoretically, black psyllium might reduce the effects of carbamazepine and increase the risk for convulsions.
Read the full Dietary Fiber + Carbamazepine interactionCarbenicillin Indanyl SodiumGeocillin
How Carbenicillin Indanyl Sodium interacts with Performance Probiotic Natural Acai Flavor — through 2 ingredients. Tap an ingredient for the detail:
Bacillus Subtilis De-111Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B.
Read the full Bacillus Subtilis De-111 + Carbenicillin Indanyl Sodium interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Carbenicillin Indanyl Sodium interactionCefaclorCeclor, Ceclor CD
How Cefaclor interacts with Performance Probiotic Natural Acai Flavor — through 2 ingredients. Tap an ingredient for the detail:
Bacillus Subtilis De-111Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B.
Read the full Bacillus Subtilis De-111 + Cefaclor interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Cefaclor interactionCefadroxilCef-Tab, Duricef, Ultracef
How Cefadroxil interacts with Performance Probiotic Natural Acai Flavor — through 2 ingredients. Tap an ingredient for the detail:
Bacillus Subtilis De-111Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B.
Read the full Bacillus Subtilis De-111 + Cefadroxil interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Cefadroxil interactionCefamandoleMandol
How Cefamandole interacts with Performance Probiotic Natural Acai Flavor — through 1 ingredient. Tap an ingredient for the detail:
Bacillus Subtilis De-111Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B.
Read the full Bacillus Subtilis De-111 + Cefamandole interactionCefazolinAncef
How Cefazolin interacts with Performance Probiotic Natural Acai Flavor — through 1 ingredient. Tap an ingredient for the detail:
Bacillus Subtilis De-111Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B.
Read the full Bacillus Subtilis De-111 + Cefazolin interactionCefdinirOmnicef
How Cefdinir interacts with Performance Probiotic Natural Acai Flavor — through 2 ingredients. Tap an ingredient for the detail:
Bacillus Subtilis De-111Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B.
Read the full Bacillus Subtilis De-111 + Cefdinir interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Cefdinir interactionCefditoren PivoxilSpectracef
How Cefditoren Pivoxil interacts with Performance Probiotic Natural Acai Flavor — through 2 ingredients. Tap an ingredient for the detail:
Bacillus Subtilis De-111Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B.
Read the full Bacillus Subtilis De-111 + Cefditoren Pivoxil interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Cefditoren Pivoxil interactionCefepimeMaxipime
How Cefepime interacts with Performance Probiotic Natural Acai Flavor — through 1 ingredient. Tap an ingredient for the detail:
Bacillus Subtilis De-111Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B.
Read the full Bacillus Subtilis De-111 + Cefepime interactionCefiderocol Sulfate TosylateFetroja
How Cefiderocol Sulfate Tosylate interacts with Performance Probiotic Natural Acai Flavor — through 1 ingredient. Tap an ingredient for the detail:
Bacillus Subtilis De-111Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B.
Read the full Bacillus Subtilis De-111 + Cefiderocol Sulfate Tosylate interactionCefiximeSuprax
How Cefixime interacts with Performance Probiotic Natural Acai Flavor — through 2 ingredients. Tap an ingredient for the detail:
Bacillus Subtilis De-111Antibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B.
Read the full Bacillus Subtilis De-111 + Cefixime interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Cefixime interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Performance Probiotic Natural Acai Flavor with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Dietary Fiber
Carbamazepine (Tegretol)
Theoretically, black psyllium might reduce the effects of carbamazepine and increase the risk for convulsions.
Theoretically, black psyllium might reduce carbamazepine absorption. A preliminary study using blond psyllium reported decreased carbamazepine bioavailability due to binding of the drug to psyllium, as well as reduction of available fluid in the gut for dissolution of the drug. This interaction may also occur with black psyllium.
Lithium
Theoretically, taking black psyllium at the same time as lithium might reduce lithium absorption.
The fiber in black psyllium might reduce lithium absorption and plasma levels. Some case reports describe a reduction in plasma lithium levels with concomitant administration of blond psyllium. This was reversed when psyllium was stopped. This interaction may also occur with black psyllium.
Metformin (Glucophage)
Theoretically, black psyllium might increase the therapeutic and adverse effects of metformin.
Animal research shows that concurrent consumption of blond psyllium with metformin slows and increases the absorption of metformin. This interaction may also occur with black psyllium. To avoid changes in absorption, take psyllium 30-60 minutes after metformin.
Olanzapine (Zyprexa)
Theoretically, taking black psyllium at the same time as olanzapine might reduce olanzapine absorption.
The fiber in black psyllium might decrease the absorption of olanzapine. A single case report describes a reduction in the effectiveness of olanzapine when it was concomitantly administered with an unspecified type of psyllium 3 grams orally twice daily. This effect was reversed when psyllium was stopped.
Digoxin (Lanoxin)
Theoretically, taking black psyllium at the same time as digoxin might reduce digoxin absorption and decrease digoxin levels.
Psyllium might bind digoxin in the gut. However, some clinical evidence suggests that psyllium does not impact digoxin absorption.
Ethinyl Estradiol
Theoretically, taking black psyllium at the same time as ethinyl estradiol might alter levels of estradiol.
Concurrent use of blond psyllium with ethinyl estradiol results in a slight increase in the extent of ethinyl estradiol absorption and a slower rate of absorption. This is unlikely to be clinically significant.
Oral Drugs
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Psyllium seems to have variable effects on drug absorption. To avoid changes in absorption, take psyllium 30-60 minutes after oral medications. Animal research shows that blond psyllium delays and increases the absorption of metformin and ethinyl estradiol. Case reports and animal research suggest that blond psyllium might reduce absorption of lithium, digoxin, olanzapine, and carbamazepine. Finally, some pharmacokinetic studies show that psyllium does not affect the absorption of levothyroxine or warfarin. Although many of these studies evaluated blond psyllium, the fiber content in black psyllium may have similar effects.
Bacillus subtilis DE-111
Antibiotic Drugs
Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B. subtilis.
Since B. subtilis preparations usually contain live and active organisms, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. subtilis preparations by at least 2 hours.
Brand information
Manufacturer and brand details for Performance Probiotic Natural Acai Flavor, from the product label.
AIVIA
See all AIVIA products- Name
- Nature's Sunshine Products, Inc.
- City
- Spanish Fork
- State
- UT
- ZipCode
- 84660
- Phone Number
- (800) 223-8225
- Web Address
- naturessunshine.com
Performance Probiotic Natural Acai Flavor by AIVIA: Common Questions
Does Performance Probiotic Natural Acai Flavor by AIVIA interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Will this help if I have diarrhea from antibiotics?
Does this have any inactive ingredients I should know about?
What side effects have been reported?
Can I take this if I'm pregnant or breastfeeding?
Is this safe for me if I have diabetes or kidney problems?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Performance Probiotic Natural Acai Flavor’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Black Psyllium
Interacts with 2,025 drugsBlack psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. It is best known and most studied for rel...
Read the full Black Psyllium monograph → Herb & supplement monographBacillus Subtilis
Interacts with 182 drugsBacillus subtilis is a spore-forming probiotic bacterium found in soil and some fermented foods, and it is used mainly to support gut health and digestion. Early research is promising for ce...
Read the full Bacillus Subtilis monograph →Sources & How We Checked
Performance Probiotic Natural Acai Flavor's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 28 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Black Psyllium 18 references
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
- Covington TR, et al. Handbook of Nonprescription Drugs. 11th ed. Washington, DC: American Pharmaceutical Association, 1996.
- Etman M. Effect of a bulk forming laxative on the bioavailablility of carbamazepine in man. Drug Dev Ind Pharm 1995;21:1901-6.
- Perlman BB. Interaction between lithium salts and ispaghula husk. Lancet 1990;335:416.
- Vaswani SK, Hamilton RG, Valentine MD, Adkinson NF. Psyllium laxative-induced anaphylaxis, asthma, and rhinitis. Allergy 1996;51:266-8. PubMed
- Lantner RR, Espiritu BR, Zumerchik P, Tobin MC. Anaphylaxis following ingestion of a psyllium-containing cereal. JAMA 1990;264:2534-6. DOI
- Kaplan MJ. Anaphylactic reaction to "Heartwise." N Engl J Med 1990;323:1072-3. DOI
- Nordstrom M, Melander A, Robertsson E, Steen B. Influence of wheat bran and of a bulk-forming ispaghula cathartic on the bioavailability of digoxin in geriatric in-patients. Drug Nutr Interact 1987;5:67-9..
- Robinson DS, Benjamin DM, McCormack JJ. Interaction of warfarin and nonsystemic gastrointestinal drugs. Clin Pharmacol Ther 1971;12:491-5. PubMed
- Garcia JJ, Fernandez N, Diez MJ, et al. Influence of two dietary fibers in the oral bioavailability and other pharmacokinetic parameters of ethinyloestradiol. Contraception 2000;62:253-7. PubMed
- Fernandez N, Lopez C, Díez R, et al. Drug interactions with the dietary fiber Plantago ovata husk. Expert Opin Drug Metab Toxicol 2012;8(11):1377-86.
- Semen plantaginis in: WHO Monographs on Selected Medicinal Plants, volume 1. World Health Organization, Geneva, 1999. Available at http://apps.who.int/medicinedocs/en/d/Js2200e/. Accessed November 26, 1026.
- Code of Federal Regulations, Title 21 (21CFR 101.17). Food labeling warning, notice, and safe handling statements. Available at www.ecfr.gov/cgi-bin/text-idx?SID=20f647d3b74161501f46564b915b4048&mc=true&node=se21.2.101_117&rgn=div8. Accessed December 3, 2
- Code of Federal Regulations, Title 21 (21CFR 201.319). Specific labeling requirements - water-soluble gums, hydrophilic gums, and hydrophilic mucilloids. Available at www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=201.319. Accessed Dece
- Diez R, Garcia JJ, Diez MJ, Sierra M, Sahagun AM, Fernandez N. Influence of Plantago ovata husk (dietary fiber) on the bioavailability and other pharmacokinetic parameters of metformin in diabetic rabbits. BMC Complement Altern Med. 2017 Jun 7;17(1):298. PubMed
- Chiu AC, Sherman SI. Effects of pharmacological fiber supplements on levothyroxine absorption. Thyroid. 1998;8(8):667-71. PubMed
- Merrick C, Madden CA, Capurso NA. A Case of Blunted Orally Disintegrating Olanzapine Effect Due to Coadministered Psyllium. J Clin Psychiatry 2021;82(2):20cr13633. PubMed
Bacillus Subtilis 10 references
- Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
- Lampropoulos PK, Gkentzi D, Tzifas S, Dimitriou G. Neonatal sepsis due to Bacillus subtilis. Cureus 2021;13(9):e17692. PubMed
- La Jeon Y, Yang JJ, Kim MJ, et al. Combined Bacillus licheniformis and Bacillus subtilis infection in a patient with oesophageal perforation. J Med Microbiol 2012;61(Pt 12):1766-1769. PubMed
- Wallet F, Crunelle V, Roussel-Delvallez M, Fruchart A, Saunier P, Courcol RJ. Bacillus subtilis as a cause of cholangitis in polycystic kidney and liver disease. Am J Gastroenterol 1996;91(7):1477-8.
- Velasco E, Martins CA, Tabak D, Bouzas LF. "Bacillus subtilis" infection in a patient submitted to a bone marrow transplantation. Rev Paul Med 1992;110(3):116-7.
- Kato A, Yoshifuji A, Komori K, et al. A case of Bacillus subtilis var. natto bacteremia caused by ingestion of natto during COVID-19 treatment in a maintenance hemodialysis patient with multiple myeloma. J Infect Chemother 2022;28(8):1212-1215. PubMed
- Freedman KE, Hill JL, Wei Y, et al. Examining the gastrointestinal and immunomodulatory effects of the novel probiotic Bacillus subtilis DE111. Int J Mol Sci 2021;22(5):2453. PubMed
- Lefevre M, Racedo SM, Denayrolles M, et al. Safety assessment of Bacillus subtilis CU1 for use as a probiotic in humans. Regul Toxicol Pharmacol 2017;83:54-65. PubMed
- Hanifi A, Culpepper T, Mai V, et al. Evaluation of Bacillus subtilis R0179 on gastrointestinal viability and general wellness: a randomised, double-blind, placebo-controlled trial in healthy adults. Benef Microbes 2015;6(1):19-27. PubMed
- Tokano M, Tarumoto N, Imai K, et al. A case of bacterial meningitis caused by Bacillus subtilis var. natto. Intern Med. 2022. Epub ahead of print.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC