No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Colostrum 500 mg Ingredients & Drug Interactions

by Nutricost

Capsule Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

Colostrum 500 mg is a dietary supplement by Nutricost with 1 active ingredient. Its ingredients are commonly taken for immune support, gut health and digestion, exercise recovery.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Colostrum 500 mg by Nutricost

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: bovine colostrum, a protein-rich fluid secreted by cows after birth. Each capsule delivers 500 mg.

The capsule itself is made from gelatin, and the formula includes rice flour, magnesium stearate, and silicon dioxide as inactive ingredients to hold everything together.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Bovine Colostrum's overall clinical evidence instead.

Moderate

Some clinical evidence supports Bovine Colostrum for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: HIV/AIDS-related diarrhea — rated "Possibly Effective" (Natural Medicines).
  • On file: Exercise-induced respiratory infections — rated "Possibly Effective" (Natural Medicines).
  • On file: Rotaviral diarrhea — rated "Possibly Effective" (Natural Medicines).

Bovine colostrum is possibly effective for HIV/AIDS-related diarrhea, rotaviral diarrhea (a common cause of infectious diarrhea in children), and exercise-induced respiratory infections. For necrotizing enterocolitis, a serious infection in newborns, the evidence suggests it is possibly ineffective.

The data we hold doesn't establish effectiveness for other uses.

The evidence, ingredient by ingredient Bovine Colostrum

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Bovine colostrum is generally well tolerated in most adults. A small number of trial participants reported mild bloating, nausea, diarrhea, and unsettled stomach at rates similar to those in a whey-based control group.

One individual with HIV-related cryptosporidiosis experienced nausea and vomiting, and some HIV patients on colostrum showed elevated liver function tests and decreased red blood cell counts — effects that warrant caution in people with these conditions. If you have a milk or dairy allergy, avoid this product.

Safety data during pregnancy isn't well studied, so talk with your doctor or pharmacist before using it if you're pregnant. During breastfeeding, safety hasn't been well studied either — ask your provider before starting.

Side effects, ingredient by ingredient Bovine Colostrum

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for bovine colostrum. Check the medication search tool on this page with your own drugs to be thorough, and mention this product to your doctor or pharmacist if you have any questions.

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. No medication interactions are currently documented, and safety information is well characterized.

Bovine colostrum may be worth considering if you're dealing with certain types of infectious diarrhea or want to explore options for exercise-related respiratory issues, though the evidence is modest. If you have a dairy allergy, are pregnant, or are breastfeeding, check with your doctor or pharmacist first.

No medication interactions are documented, but run your medications through the checker to be sure.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 21, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Colostrum 500 mg, straight from the product label.

Brand Nutricost
Barcode (UPC) 702669934121
Net contents 120 Capsule(s)
Market status On market
Date entered into DSLD Jul 21, 2022
DSLD ID 269405
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Colostrum 500 mg by Nutricost, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
120
UPC/BARCODE
702669934121
IngredientAmount% DV
Bovine Colostrum500 mg--

Other ingredients: Gelatin, Rice Flour, Magnesium Stearate, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Recommended Use: As a dietary supplement, take 1 capsule daily with 8-12 oz of water or as directed by your healthcare professional.

Precautions

Warning: For healthy individuals 18 years and older.

Consult a healthcare professional prior to use if you are pregnant or nursing, taking medication, or have a medical condition.

Keep out of reach of children.

Do not use if safety seal is broken or missing.

Storage

Notice: Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formula

500 mg per capsule

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

Quality Guaranteed Nutricost

Third Party Tested

Formulation

Non GMO Gluten Free Product

See for yourself

Colostrum 500 mg by Nutricost label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Colostrum 500 mg by Nutricost

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container120 Amounts shown are per serving.

Bovine Colostrum

No known
interactions
500 mg per serving

Bovine colostrum is the nutrient-rich first milk from cows, packed with antibodies, growth factors, and protein. Early research suggests it may help w...

Bovine Colostrum monograph & interactions

Other (inactive) ingredients: Gelatin, Rice Flour, Magnesium Stearate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Colostrum 500 mg by Nutricost Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Colostrum 500 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Colostrum 500 mg, from the product label.

Nutricost

See all Nutricost products
Name
Nutricost
Street Address
351 E 1750 N
City
Vineyard
State
UT
ZipCode
84059
Phone Number
(866) 438-3694
Web Address
www.nutricost.com
Pharmacist Counseling Corner

Colostrum 500 mg by Nutricost: Common Questions

Does Colostrum 500 mg by Nutricost interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Colostrum 500 mg. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Colostrum 500 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
I'm allergic to milk — can I take this?
No. Bovine colostrum comes from cow's milk, and the data advises people with milk or dairy allergies to avoid it. Talk with your doctor about other options.
What side effects should I expect?
A small number of people in trials reported mild bloating, nausea, diarrhea, and unsettled stomach at rates no higher than a control group. One person with HIV-related cryptosporidiosis had nausea and vomiting. If you have HIV or another serious infection, ask your doctor first — some patients showed changes in liver function and red blood cell counts.
Is it safe during pregnancy?
Safety data during pregnancy isn't well studied. Talk with your doctor or pharmacist before taking it if you're pregnant — they can help you weigh the unknown risks against any potential benefit.
Can I use this while breastfeeding?
Safety during breastfeeding hasn't been well studied either. Ask your provider before starting, since there isn't enough data to know whether it's safe for your baby.
Does this actually work for diarrhea?
The evidence suggests bovine colostrum is possibly effective for diarrhea caused by HIV/AIDS or rotavirus. For other causes of diarrhea, we don't have enough data to know how well it works.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Colostrum 500 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Colostrum 500 mg label
Go deeper

The Full Monographs Behind Colostrum 500 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Colostrum 500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 8 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Bovine Colostrum 8 references
  1. Lewis CJ. Letter to reiterate certain public health and safety concerns to firms manufacturing or importing dietary supplements that contain specific bovine tissues. FDA. Available at: www.cfsan.fda.gov/~dms/dspltr05.html.
  2. Greenberg PD, Cello JP. Treatment of severe diarrhea caused by Cryptosporidium parvum with oral bovine immunoglobulin concentrate in patients with AIDS. J Acquir Immune Defic Syndr Hum Retrovirol 1996;13:348-54. PubMed
  3. Duff WR, Chilibeck PD, Rooke JJ, Kaviani M, Krentz JR, Haines DM. The effect of bovine colostrum supplementation in older adults during resistance training. Int J Sport Nutr Exerc Metab. 2014 Jun;24(3):276-85. PubMed
  4. Sanctuary MR, Kain JN, Chen SY, et al. Pilot study of probiotic/colostrum supplementation on gut function in children with autism and gastrointestinal symptoms. PLoS One. 2019;14(1):e0210064. PubMed
  5. Porcaro F, Caminiti L, Crisafulli G, Guglielmo F, Pajno GB. Anaphylaxis to cutaneous exposure to bovine colostrum based cream. Asian Pac J Allergy Immunol. 2019;37(1):9-11.
  6. Yan X, Pan X, Ding L, et al. Bovine colostrum to supplement the first feeding of very preterm infants: The PreColos randomized controlled trial. Clin Nutr 2023;42(8):1408-1417. PubMed
  7. Halasa M, Skonieczna-Zydecka K, Machalinski B, Bühner L, Baskiewicz-Halasa M. Six Weeks of Supplementation with Bovine Colostrum Effectively Reduces URTIs Symptoms Frequency and Gravity for Up to 20 Weeks in Pre-School Children. Nutrients 2023;15(16):3626 PubMed
  8. Simonsen MB, Kappel SS, Aunsholt L, Möller S, Sangild PT, Zachariassen G. Mineral supplementation for very preterm infants fed fortified human milk. J Pediatr Gastroenterol Nutr 2024;78(6):1389-1397. PubMed

See these in context on the Bovine Colostrum monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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