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Dietary supplement

Coptis Teapills Ingredients & Drug Interactions

by Plum Flower

Coptis Teapills label
See full label image
Tablet Or Pill Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Coptis Teapills against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Coptis Teapills is a dietary supplement by Plum Flower with 1 active ingredient. Its ingredients are commonly taken for digestive upset and diarrhea, mouth sores and sore throat, inflammation.Based on those ingredients, 643 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Coptis chinensis. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Coptis Teapills by Plum Flower

Ask about any prescription or over-the-counter medication and we check it for interactions with Coptis Teapills by Plum Flower — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Coptis Teapills by Plum Flower

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 1 active ingredient.
  • “Proprietary Extract Blend” is a proprietary blend — the label gives one combined amount (680 mg) without saying how much of each component you get.

Coptis Teapills contains one active ingredient: a proprietary extract blend built around goldthread (Coptis chinensis). The product also includes inactive ingredients — maltose, magnesium silicate, activated charcoal, and China wax — which are fillers and binders that help form and stabilize the tablet.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Goldthread product and its label doesn't state a use — see Goldthread's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

We hold no effectiveness ratings for goldthread in our data, so we can't tell you from our records whether this product is proven to work for any particular purpose.

The evidence, ingredient by ingredient Goldthread

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 0 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Goldthread may be tolerated for short periods by some adults, but human safety data are limited and quality varies between products, so this isn't a supplement to take long-term without talking to your pharmacist or doctor first. The safety data advises against goldthread during pregnancy — berberine may harm the fetus.

The same goes for breastfeeding: berberine can pass into breast milk and may harm infants, so it should be avoided if you're nursing.

Side effects, ingredient by ingredient Goldthread

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Goldthread.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: immunosuppressants / transplant drugs.
  • For scale: 644 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Coptis Teapills, double-check any drugs metabolized by the liver enzyme CYP3A4 (a very large group that includes cholesterol medications like lovastatin) and cyclosporine (Neoral, Sandimmune). Both interactions are Moderate.

Use the search tool on this page to look up your specific medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and some safety-information gaps remain.

Coptis Teapills is a single-ingredient goldthread extract. If you take any medications — especially cholesterol drugs, immunosuppressants like cyclosporine, or anything metabolized by your liver — check them against the interaction tool below before starting.

Pregnant and breastfeeding people should avoid it.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 25, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Coptis Teapills, straight from the product label.

Brand Plum Flower
Barcode (UPC) 739934837085
Net contents 1.2 Ounce(s); 34 Gram(s); 200 Pill(s)
Market status On market
Date entered into DSLD Jun 25, 2025
DSLD ID 331210
Product type Botanical
Supplement form Tablet Or Pill
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Coptis Teapills by Plum Flower, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
4 Pill(s)
Maximum serving Sizes:
4 Pill(s)
Servings per container
50
UPC/BARCODE
739934837085
IngredientAmount% DV
Proprietary Extract Blend680 mg--
Coptis chinensis0 NP--

Other ingredients: Maltose, Magnesium Silicate, Carbon, Activated, China Wax

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

Herbal Supplement

Suggested/Recommended/Usage/Directions

Take 4 pills 3 times daily or as directed by your health care practitioner

Precautions

Keep out of reach of children

Seals/Symbols

Sourced sustainably FDA Registered Species Verified Lab Tested Quality Verified cGMP Compliant Made at a cGMP Certified Facility

General Statements

Foci Pharmaceutical 1929 Foci Pharmaceutical

Formulation

Plum Flower Guarantee US owned & operated since 1969. Made in China in partnership with the award-winning Lanzhou Foci Pharmaceutical Co. Ltd.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Coptis Teapills by Plum Flower label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Coptis Teapills label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Coptis Teapills by Plum Flower

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size4 Pill(s) Dosage formTablet Or Pill Servings per container50 Amounts shown are per serving.

Proprietary Extract Blend

680 mg per serving

Other (inactive) ingredients: Maltose, Magnesium Silicate, Carbon, Activated, China Wax. These complete the product’s ingredient list but are not active constituents.

Interaction report

Coptis Teapills by Plum Flower Drug Interactions

Want to check YOUR meds against Coptis Teapills?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
643Drugs
643 Moderate

Ingredients driving the most interactions

Coptis chinensis 643

Individual Drug Interactions

The ingredients in Coptis Teapills interact with 643 drugs. Click any drug to see the details.

1 of the 1 ingredient in Coptis Teapills interact with drugs. Each result below shows which ingredient is responsible. Coptis chinensis

Each ingredient & the kinds of drugs it affects

For each ingredient in Coptis Teapills with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Coptis chinensis2 drug types · 643 drugs

Cyclosporine (Neoral, Sandimmune)

Berberine, a constituent of goldthread, can reduce metabolism of cyclosporine and increase serum levels. It might inhibit cytochrome P450 3A4 (CYP3A4), which metabolizes cyclosporine.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

There's very preliminary evidence that berberine, a constituent of goldthread, might inhibit cytochrome P450 3A4 (CYP3A4) enzyme. So far, this interaction has not been reported in humans. However, watch for an increase in the levels of drugs metabolized by CYP3A4 in patients taking goldthread. Some drugs metabolized by CYP3A4 include lovastatin (Mevacor), clarithromycin (Biaxin), indinavir (Crixivan), sildenafil (Viagra), triazolam (Halcion), and numerous others. Use goldthread cautiously or avoid in patients taking these drugs.

Likelihood Possible Evidence D
Coptis chinensis full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Coptis Teapills, from the product label.

Plum Flower

Name
Mayway Herbs
City
Oakland
State
CA
Web Address
www.plumflowerherbs.com
Pharmacist Counseling Corner

Coptis Teapills by Plum Flower: Common Questions

Does Coptis Teapills by Plum Flower interact with any medications?
Yes. Based on its ingredients, Coptis Teapills has a known interaction with 643 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Coptis Teapills contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while I'm pregnant?
No — the safety data advises against goldthread in pregnancy because berberine may harm the fetus.
Is it safe to breastfeed while taking Coptis Teapills?
No — berberine passes into breast milk and may harm infants, so you should avoid this product while nursing.
How long can I safely take this product?
The data show that goldthread may be tolerated short-term by some adults, but human safety data are limited and product quality varies. It's not something to take long-term without talking to your pharmacist or doctor first.
What is goldthread used for?
We don't hold effectiveness data for goldthread in our system, so we can't tell you what it's proven to do. Your pharmacist or the product label may have more information on that.
Does this product have any fillers?
Yes — it contains maltose, magnesium silicate, activated charcoal, and China wax as inactive ingredients to form and stabilize the tablet.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Coptis Teapills is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Coptis Teapills label
Go deeper

The Full Monographs Behind Coptis Teapills’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Goldthread

Interacts with 643 drugs

Goldthread is a traditional Chinese and East Asian herb whose root is rich in berberine, a compound being studied for blood sugar, cholesterol, and antimicrobial effects. Strong human eviden...

Read the full Goldthread monograph →
Sources

Sources & How We Checked

Coptis Teapills's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Goldthread 3 references
  1. Chan E. Displacement of bilirubin from albumin by berberine. Biol Neonate 1993;63:201-8. PubMed
  2. Wu X, Li Q, Xin H, Yu A, Zhong M. Effects of berberine on the blood concentration of cyclosporin A in renal transplanted recipients: clinical and pharmacokinetic study. Eur J Clin Pharmacol 2005;61:567-72. PubMed
  3. Chuang CH, Doyle P, Wang JD, et al. Herbal medicines used during the first trimester and major congenital malformations: an analysis of data from a pregnancy cohort study. Drug Saf 2006;29:537-48. PubMed

See these in context on the Goldthread monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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