Interactions on record — worth a quick check against your medications. Based on 1 of 3 ingredients. Check your meds →
Dietary supplement

Cytozyme-LV Ingredients & Drug Interactions

by Biotics Research Corporation

Tablet Or Pill Category: Non-nutrient/non-botanical
Most serious interaction: Minor
The interaction bottom line Most serious interaction: Minor

Cytozyme-LV is a dietary supplement by Biotics Research Corporation with 3 active ingredients. Its ingredients are commonly taken for anemia and low iron, vitamin b12 support, general energy and fatigue.Based on those ingredients, 3 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Neonatal Liver Concentrate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Cytozyme-LV by Biotics Research Corporation

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Cytozyme-LV contains 3 active ingredients: superoxide dismutase and catalase, which are antioxidant enzymes, plus neonatal liver concentrate — a tissue extract from young animal livers. The inactive ingredients are stearic acid, cellulose, magnesium stearate, and food glaze — the binders and coating that hold the tablet together.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Liver Extract product and its label doesn't state a use — see Liver Extract's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for liver extract in chronic fatigue syndrome is rated possibly ineffective based on available data. For hepatitis C, there isn't enough reliable evidence to rate its effectiveness one way or the other.

We don't have effectiveness ratings on file for the other two active ingredients in this product.

The evidence, ingredient by ingredient Liver Extract

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

No adverse reactions have been reported for liver extract. However, safety hasn't been thoroughly studied, and there are a few things to be aware of.

Liver extract can deliver very high levels of vitamin A and iron, which is a concern in pregnancy — the data advises against use during pregnancy unless your doctor says otherwise. There's also a theoretical concern about contamination, since liver extract comes from raw animal liver from slaughterhouses, and BSE (bovine spongiform encephalopathy, a serious infectious disease in cattle) has been reported in several countries; no human cases from liver extract have been documented, but the source and manufacturing country do matter.

Talk with your pharmacist about where this product's liver came from.

Side effects, ingredient by ingredient Liver Extract

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Liver Extract.
  • The most serious interaction on file is rated Minor.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 3 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you're on warfarin (Coumadin), a blood thinner, or taking iron supplements or iron-containing medications, check with your pharmacist before starting this product. The interactions are minor, but your dose or INR may need monitoring.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Only minor medication interactions are documented, and safety information is well characterized.

This product is geared toward liver support and chronic fatigue, though the evidence for the latter is weak. If you take warfarin or iron supplements, double-check with your pharmacist first — the interactions are minor but real.

Pregnant or breastfeeding? Avoid it unless your doctor approves.

The main safety concern is where the liver extract comes from, so ask about the sourcing.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated May 24, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Cytozyme-LV, straight from the product label.

Brand Biotics Research Corporation
Net contents 60 Tablet(s)
Market status On market
Date entered into DSLD May 24, 2013
DSLD ID 21635
Product type Non-nutrient/non-botanical
Supplement form Tablet Or Pill
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Cytozyme-LV by Biotics Research Corporation, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
1 Tablet(s)
IngredientAmount% DV
Superoxide Dismutase20 mcg--
Catalase20 mcg--
Neonatal Liver Concentrate300 mg--

Other ingredients: Stearic Acid, Cellulose, Magnesium Stearate, Food Glaze

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

RECOMMENDATION: One (1) tablet one (1) to three (3) times each day as a dietary supplement or as otherwise recommended by a healthcare professional.

Precautions

KEEP OUT OF REACH OF CHILDREN

Storage

Store in a cool, dry area.

General Statements

Sealed with an imprinted safety seal for your protection.

Specially grown, biologically active vegetable culture containing naturally occuring and/or organically bound phytochemicals including polyphenolic compounds with SOD and catalase, dehydrated at low temperature to preserve associated enzyme factors.

Lot Number: Exp. Date:

General

Rev. 1/08

FDA Statement of Identity

Dietary Supplement

Formula

with Neonatal Liver Concentrate

Brand IP Statement(s)

(C) Copyright 2008

See for yourself

Cytozyme-LV by Biotics Research Corporation label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Cytozyme-LV by Biotics Research Corporation

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Superoxide Dismutase

20 mcg per serving

Catalase

20 mcg per serving

Neonatal Liver Concentrate

Interacts with
3 drugs
300 mg per serving Form: Bovine

Liver extract is a dried or concentrated form of animal liver that is naturally rich in iron, vitamin B12, vitamin A, and other nutrients. It was once...

Neonatal Liver Concentrate monograph & interactions

Other (inactive) ingredients: Stearic Acid, Cellulose, Magnesium Stearate, Food Glaze. These complete the product’s ingredient list but are not active constituents.

Interaction report

Cytozyme-LV by Biotics Research Corporation Drug Interactions

Want to check YOUR meds against Cytozyme-LV?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
3Drugs
3 Minor

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Cytozyme-LV with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Neonatal Liver Concentrate2 drug types · 3 drugs

Iron

Liver extract can contain heme iron. Taking liver extract with iron-containing medications or supplements may increase total iron intake and could increase the risk of gastrointestinal adverse effects or excessive iron accumulation. The risk is greater with high doses, prolonged use, or in individuals with hemochromatosis or another iron-overload disorder. Review the iron content of the liver extract and the total elemental iron dose. Avoid unnecessary duplicate iron supplementation and consider monitoring ferritin and transferrin saturation when clinically appropriate.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Liver extract products may contain small and variable amounts of vitamin K. Theoretically, starting, stopping, or substantially changing the amount of liver extract used could reduce the anticoagulant effect of warfarin and lower the INR. However, this interaction has not been directly studied or reported in humans, and the vitamin K content of liver extract products is generally not standardized. Consider monitoring the INR after a meaningful change in liver extract use.

Likelihood Possible Evidence C
The maker

Brand information

Manufacturer and brand details for Cytozyme-LV, from the product label.

Biotics Research Corporation

See all Biotics Research Corporation products
Name
BIOTICS RESEARCH CORP.
City
Rosenberg
State
Texas
Phone Number
(281) 344-0909
Pharmacist Counseling Corner

Cytozyme-LV by Biotics Research Corporation: Common Questions

Does Cytozyme-LV by Biotics Research Corporation interact with any medications?
Yes. Based on its ingredients, Cytozyme-LV has a known interaction with 3 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Cytozyme-LV contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this with warfarin?
Liver extract may contain small amounts of vitamin K, which could theoretically weaken warfarin's blood-thinning effect. This hasn't been proven in humans, but it's a minor concern worth discussing with your pharmacist — they may want to monitor your INR (clotting marker) if you start it.
Is it safe to take with iron supplements?
Liver extract contains heme iron naturally, so combining it with iron supplements or iron-containing medications could increase your total iron intake and cause stomach upset or iron overload, especially at high doses or over time. Your pharmacist can help you figure out if that's a problem for you.
Can I take this while pregnant?
No — liver extract can deliver very high levels of vitamin A, which may harm a developing baby. Avoid it in pregnancy unless your doctor specifically says it's okay.
Will this help my chronic fatigue?
The evidence doesn't support it — liver extract is rated possibly ineffective for chronic fatigue syndrome based on available data. You may want to talk with your doctor about other approaches.
What are superoxide dismutase and catalase?
They're antioxidant enzymes — proteins that help neutralize harmful free radicals in cells. We don't have effectiveness or safety data on file for them in this product.
Where does the liver in this product come from?
The facts don't say. Since there's a theoretical concern about contamination or disease in raw animal liver, especially from countries where BSE was reported, it's worth asking the manufacturer or your pharmacist where it's sourced.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Cytozyme-LV is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Cytozyme-LV label
Sources

Sources & How We Checked

Cytozyme-LV's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Liver Extract 4 references
  1. Lewis CJ. Letter to reiterate certain public health and safety concerns to firms manufacturing or importing dietary supplements that contain specific bovine tissues. FDA. Available at: www.cfsan.fda.gov/~dms/dspltr05.html.
  2. Kaslow JE, Rucker L, Onishi R. Liver extract-folic acid-cyanocobalamin vs placebo for chronic fatigue syndrome. Arch Intern Med 1989;149:2501-3. DOI
  3. Ebinuma, H., Saito, H., Tada, S., Masuda, T., Kamiya, T., Nishida, J., Yoshioka, M., and Ishii, H. Additive therapeutic effects of the liver extract preparation mixture adelavin-9 on interferon-beta treatment for chronic hepatitis C. Hepatogastroenterolog
  4. Saito, H., Ebinuma, H., Tada, S., Tsunematsu, S., Atsukawa, K., Masuda, T., Tsuchiya, M., and Ishii, H. Enhancing effect of the liver extract and flavin adenin dinucleotide mixture on anti-viral efficacy of interferon in patients with chronic hepatitis C. PubMed

See these in context on the Liver Extract monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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