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Dietary supplement

Dairy & Lactose Tolerance Ingredients & Drug Interactions

by ProCaps

Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Dairy & Lactose Tolerance is a dietary supplement by ProCaps with 3 active ingredients. Its ingredients are commonly taken for digestive support for protein digestion, wound cleaning (debridement of dead tissue), sore throat and inflammation.Based on those ingredients, 141 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Bromelain, Papain. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Dairy & Lactose Tolerance by ProCaps

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 3 active ingredients.
  • “Proprietary Digestive Enzyme Blend” is a proprietary blend — the label gives one combined amount (415 mg) without saying how much of each component you get.

This product has three active ingredients. Lactase is an enzyme that helps your body break down lactose (milk sugar), which is the main reason you'd take this for dairy tolerance.

Papain and bromelain are both protein-digesting enzymes—papain comes from papaya, and bromelain comes from pineapple—included to support overall digestion. The capsule itself is made from cellulose, a plant-based inactive ingredient.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Digests lactose and relieves lactose intolerance.
  • We looked for evidence on: Lactose intolerance, dairy digestion, milk sugar digestion, post-dairy bloating.
  • The strongest evidence on file: Lactase is rated "Effective" for Lactose intolerance (Natural Medicines).

Lactase is effective for lactose intolerance—it works by breaking down the milk sugar your body can't digest on its own. Papain and bromelain have been studied for various conditions (cancer, burns, allergies, wound healing, and others), but the evidence we hold shows insufficient reliable data to rate them for those purposes.

They're included here as digestive support ingredients, though their specific contribution to dairy tolerance isn't detailed in the product information we have.

The evidence, ingredient by ingredient Papain Bromelain Lactase

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lactase is generally well tolerated and likely safe in pregnancy and lactation. Papain and bromelain are generally tolerated short-term at normal doses, but high doses of papain can be unsafe.

Allergic reactions are the main concern with papain and bromelain—they can cause itching, sneezing, digestive upset, skin rashes, and in people exposed to the powder occupationally, respiratory reactions. Papain is considered possibly unsafe in pregnancy; bromelain is best avoided in pregnancy and while breastfeeding because there isn't enough safety data.

Side effects, ingredient by ingredient Papain Bromelain Lactase

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 3 matched ingredients can interact with medications — Papain, Bromelain.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 141 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your medications before starting if you take warfarin or any blood thinner (anticoagulant), aspirin, or other antiplatelet drugs—papain and bromelain may increase bleeding risk. If you're on tetracycline antibiotics, bromelain might theoretically affect how much gets into your system, though real-world evidence is mixed.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product is straightforward if you're looking for lactase to help with lactose intolerance and don't take blood thinners. If you take warfarin, any anticoagulant, or aspirin-type drugs, check with your pharmacist first—the papain and bromelain could interfere.

Pregnant or breastfeeding? Talk to your doctor; papain and bromelain aren't well studied in those situations.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 25, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Dairy & Lactose Tolerance, straight from the product label.

Brand ProCaps
Barcode (UPC) 288955
Net contents 240 Easy-To-Swallow Capsule(s)
Market status On market
Date entered into DSLD Jun 25, 2025
DSLD ID 331540
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), No Allergies, Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Dairy & Lactose Tolerance by ProCaps, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
3 Capsule(s)
Servings per container
240
UPC/BARCODE
288955
IngredientAmount% DV
Papain0 NP--
Bromelain0 NP--
Lactase0 NP--
Proprietary Digestive Enzyme Blend415 mg--

Other ingredients: Cellulose, Natural

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use Based upon the amount of lactose-containing foods ingested, consume one to three capsules immediately before, during or following that meal.

General Statements

For questions about the use of this product call 800.800.1200. Questions? Reorders? 800.800.1200 procaps.com Andrew Lessman

Dairy products are an excellent source of calcium and protein, but unfortunately for many people, they are also difficult to digest comfortably. The culprit is lactose, the natural sugar present in milk and dairy products, which can be very difficult for many people to digest, particularly as we get older, causing gas, diarrhea, bloating and significant discomfort. The severity of the gastrointestinal discomfort - referred to as "Lactose Intolerance" depends on the individual and can in many cases prevent the consumption and certainly, the enjoyment of any dairy products.

Formulation

Since 1979, Unsurpassed purity, quality and efficacy. 100% Solar production Zero-carbon footprint 100% Solar

Digests lactose (Dairy & milk sugar) Relieves lactose intolerance

Contains no additives or common allergens

Contains No milk, soy, yeast, wheat, gluten, sodium, salt, sugar, fat, cholesterol, color, preservative, common allergens, genetically modified (GMO) ingredients or manufacturing additives.

Brand IP Statement(s)

Copyright 2024 ProCaps Laboratories

Formula

All-natural enzyme complex

Dairy and Lactose Tolerance is a mild, all-natural enzyme supplement designed to gently and effectively enhance your body’s natural digestion of dairy products and lactose (“milk sugar”). Dairy and Lactose Tolerance contains enzymes to help your body break down lactose and avoid discomfort. As we get older, we produce less lactase (the enzyme that digests lactose), so the dairy products we formerly enjoyed in our youth are no longer comfortable to consume. The mild, yet powerful, natural enzymes in Dairy and Lactose Tolerance help to relieve dairy and lactose-related upset while you enjoy the flavor and health benefits of dairy.

FDA Statement of Identity

Dietary Supplement

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

See for yourself

Dairy & Lactose Tolerance by ProCaps label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Dairy & Lactose Tolerance by ProCaps

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container240 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Digestive Enzyme Blend

415 mg per serving

Other (inactive) ingredients: Cellulose, Natural. These complete the product’s ingredient list but are not active constituents.

Interaction report

Dairy & Lactose Tolerance by ProCaps Drug Interactions

Want to check YOUR meds against Dairy & Lactose Tolerance?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
141Drugs
122 Moderate 19 Minor

Ingredients driving the most interactions

Bromelain 141
Papain 2

Each ingredient & the kinds of drugs it affects

For each ingredient in Dairy & Lactose Tolerance with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Bromelain2 drug types · 141 drugs

Anticoagulant/Antiplatelet Drugs

Bromelain may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
There is one case report of a patient experiencing minor bruising while taking bromelain with naproxen. Bromelain is thought to have antiplatelet activity. Whether this interaction is of concern with topical bromelain is unclear. Interference with coagulation of burn wounds has been reported in a patient receiving bromelain-based enzymatic debridement. However, observational research has found that topical bromelain debridement is not associated with increases or decreases in laboratory markers of coagulation when compared with surgical debridement.

Likelihood Possible Evidence D
Tetracycline Antibiotics

Theoretically, bromelain might increase levels of tetracycline antibiotics.
Laboratory research suggests that bromelain might increase the absorption of tetracycline antibiotics. However, a study in healthy adults reported no difference in tetracycline plasma levels when a 500 mg dose was taken with or without bromelain 80 mg.

Likelihood Possible Evidence B

Papain1 drug type · 2 drugs

Warfarin (Coumadin)

Theoretically, papain might increase the effects and side effects of warfarin.
In one case report, a patient previously stable on warfarin was found to have an international normalization ratio (INR) of 7.4, which was attributed to ingestion of a supplement containing papain from papaya extract.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Dairy & Lactose Tolerance, from the product label.

ProCaps

See all ProCaps products
Name
ProCaps Labs
City
Henderson
State
NV
ZipCode
89011
Phone Number
800.800.1200
Web Address
ProCaps.com
Pharmacist Counseling Corner

Dairy & Lactose Tolerance by ProCaps: Common Questions

Does Dairy & Lactose Tolerance by ProCaps interact with any medications?
Yes. Based on its ingredients, Dairy & Lactose Tolerance has a known interaction with 141 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Dairy & Lactose Tolerance contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this help if I'm lactose intolerant?
Lactase is effective for lactose intolerance. It's an enzyme that breaks down the lactose in milk and dairy products, which your body can't do on its own. Papain and bromelain are added for digestive support.
What are the side effects of papain and bromelain?
Both are generally well tolerated at normal doses. The most common side effects are allergic reactions in sensitive people—itching, sneezing, runny nose, watery eyes, rashes, and stomach cramping. Digestive upset, diarrhea, and headache can also occur. High doses of papain carry a small risk of serious stomach damage. Exposure to the powder (not the capsule) can cause respiratory allergies.
Is it safe to take this while pregnant?
Lactase is likely safe in pregnancy. Papain is considered possibly unsafe, and there isn't enough data on bromelain to recommend it. Talk with your doctor or pharmacist about whether this product is right for you during pregnancy.
Can I take this while breastfeeding?
Lactase is likely safe while breastfeeding. Papain: there isn't enough safety data, so it's best to avoid it. Bromelain: safety while breastfeeding is unknown, so avoid it. Ask your pharmacist or doctor if you have questions.
Does it contain any fillers or additives?
The capsule is made from cellulose (a plant-based inactive ingredient). There are no other listed inactive ingredients.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Dairy & Lactose Tolerance is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Dairy & Lactose Tolerance label
Sources

Sources & How We Checked

Dairy & Lactose Tolerance's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 31 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Papain 11 references
  1. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  2. Shaw D, Leon C, Kolev S, Murray V. Traditional remedies and food supplements: a 5-year toxicological study (1991-1995). Drug Saf 1997;17:342-56.
  3. Shuttleworth D, Hill S, Marks R, Connelly DM. Relief of experimentally induced pruritus with a novel eutectic mixture of local anaesthetic agents. Br J Dermatol 1988;119:535-40.
  4. Mansfield LE, Ting S, Haverly RW, Yoo TJ. The incidence and clinical implications of hypersensitivity to papain in an allergic population, confirmed by blinded oral challenge. Ann Allergy 1985;55:541-3.
  5. Martin, T., Uhder, K., Kurek, R., Roeddiger, S., Schneider, L., Vogt, H. G., Heyd, R., and Zamboglou, N. Does prophylactic treatment with proteolytic enzymes reduce acute toxicity of adjuvant pelvic irradiation? Results of a double-blind randomized trial PubMed
  6. Walker-Renard, P. Update on the medicinal management of phytobezoars. Am J Gastroenterol. 1993;88(10):1663-1666.
  7. Tymoszuk D, Wiszniewska M, Walusiak-Skorupa J. Papain-induced occupational rhinoconjunctivitis and asthma - A case report. Med Pr 2016;67(1):109-12. PubMed
  8. Soto-Mera MT, López-Rico MR, Filgueira JF, et al. Occupational allergy to papain. Allergy 2000;55(10):983-4. PubMed
  9. Tarlo SM, Shaikh W, Bell B, et al. Papain-induced allergic reactions. Clin Allergy 1978;8(3):207-15. PubMed
  10. Baur X, König G, Bencze K, Fruhmann G. Clinical symptoms and results of skin test, RAST and bronchial provocation test in thirty-three papain workers: Evidence for strong immunogenic potency and clinically relevant proteolytic e?ects of airborne papain. C
  11. Novey HS, Keenan WJ, Fairshter RD, Wells ID, Wilson AF, Culver BD. Pulmonary disease in workers exposed to papain: clinico-physiological and immunological studies. Clin Allergy 1980;10(6):721-31. PubMed

See these in context on the Papain monograph →

Bromelain 19 references
  1. Nettis E, Napoli G, Ferrannini A, Tursi A. IgE-mediated allergy to bromelain. Allergy 2001;56:257-8. PubMed
  2. Taussig SJ, Batkin S. Bromelain, the enzyme complex of pineapple (Ananas comosus) and its clinical application. An update. J Ethnopharmacol 1988;22:191-203.. PubMed
  3. Bradbrook ID, Morrison PJ, Rogers HJ. The effect of bromelain on the absorption of orally administered tetracycline. Br J Clin Pharmacol 1978;6:552-4. PubMed
  4. Bush TM, Rayburn KS, Holloway SW, et al. Adverse interactions between herbal and dietary substances and prescription medications: a clinical survey. Altern Ther Health Med 2007;13:30-5.
  5. Brien S, Lewith G, Walker AF, et al. Bromelain as an adjunctive treatment for moderate-to-severe osteoarthritis of the knee: a randomized placebo-controlled pilot study. QJM 2006;99:841-50. PubMed
  6. Mori S, Ojima Y, Hirose T, et al. The clinical effect of proteolytic enzyme containing bromelain and trypsin on urinary tract infection evaluated by double blind method. Acta Obstet Gynaecol Jpn 1972;19:147-53.
  7. Glaser D, Hilberg T. The influence of bromelain on platelet count and platelet activity in vitro. Platelets 2006;17:37-41. PubMed
  8. Heinicke R M, van der Wal L, Yokoyama M. Effect of bromelain (Ananase) on human platelet aggregation. Experientia 1972;28:844-5. PubMed
  9. Gailhofer, G., Wilders-Truschnig, M., Smolle, J., and Ludvan, M. Asthma caused by bromelain: an occupational allergy. Clin Allergy 1988;18(5):445-450. PubMed
  10. Mattei, O., Fabri, G., and Farina, G. [Occupational health experience regarding four cases of asthma due to bromelain (author's transl)]. Medicina del Lavoro 1979;70(5):404-409.
  11. Galleguillos, F. and Rodriguez, J. C. Asthma caused by bromelin inhalation. Clin Allergy 1978;8(1):21-24. PubMed
  12. Perez-Camo I, Quirce S, Duran MA, and et al. Latex allergy: evidence of cross-reactivity with papain and bromelain [abstract]. Allergy 1996;51(suppl 31):48.
  13. Martin GJ, Ehrenreich J, and Asbell N. Bromelain: pineapple proteases with anti-edema activity. Exp Med Surg 1962;20:227-247.
  14. Kasemsuk T, Saengpetch N, Sibmooh N, Unchern S. Improved WOMAC score following 16-week treatment with bromelain for knee osteoarthritis. Clin Rheumatol. 2016 Oct;35(10):2531-40. PubMed
  15. Kutlu Ö, DemirbaS A, Elmas ÖF, Güvenç U, Metin A. Fixed drug eruption: a new side effect of bromelain. Contact Dermatitis 2020. Online ahead of print. PubMed
  16. Shoham Y, Shapira E, Haik J, et al. Bromelain-based enzymatic debridement of chronic wounds: Results of a multicentre randomized controlled trial. Wound Repair Regen 2021;29(6):899-907. PubMed
  17. Pfister P, Garcia Wendel PD, Kim BS, et al. Coagulation side effects of enzymatic debridement in burned patients. Burns 2022. PubMed
  18. Hasham S, Riyat H, Fletcher A, O'Boyle CP, Alexander S. To bleed or not to bleed? Case series and discussion of haemorrhage risk with enzymatic debridement in burn injuries. Scars Burn Heal 2023;9:20595131231168333. PubMed
  19. Leelakanok N, Petchsomrit A, Janurai T, Saechan C, Sunsandee N. Efficacy and safety of bromelain: A systematic review and meta-analysis. Nutr Health 2023. PubMed

See these in context on the Bromelain monograph →

Lactase 1 reference
  1. Laukkanen A, Ruoppi P, Remes S, Koistinen T, Mäkinen-Kiljunen S. Lactase-induced occupational protein contact dermatitis and allergic rhinoconjunctivitis. Contact Dermatitis. 2007;57(2):89-93. PubMed

See these in context on the Lactase monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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