No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 3 of 6 ingredients. Check your meds →
Dietary supplement

Digestive Enzymes 75 mg Ingredients & Drug Interactions

by Pure Prescriptions

Capsule Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

Digestive Enzymes 75 mg is a dietary supplement by Pure Prescriptions with 6 active ingredients. Its ingredients are commonly taken for digestive support, bloating and gas, fat digestion.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Digestive Enzymes 75 mg by Pure Prescriptions

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 1 of its 6 active ingredients.

This product contains six active digestive enzymes in a 75 mg capsule. Lipase breaks down fats, lactase helps digest dairy sugar (lactose), and neutral protease breaks down proteins — these are the three enzymes we have safety and effectiveness data for.

The other three — amylase (which works on starches), cellulase, and digezyme — round out the blend. The capsule also contains rice flour as an inactive ingredient.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded its ingredients' overall clinical evidence instead.

Strong

Strong clinical evidence supports its ingredients for:

Why this rating?
  • The label markets general wellness (“digestive support”), not a specific health condition, so there is no single claim to grade against clinical-evidence data.
  • Since the label doesn't commit to one use, we graded the ingredients' overall clinical evidence instead.
  • On file: Lactose intolerance — rated "Effective" (Lactase) (Natural Medicines).

The evidence varies by enzyme. Lactase is effective for lactose intolerance — if you have trouble digesting dairy, this ingredient has solid backing.

For lipase and the other enzymes in conditions like dyspepsia (indigestion) or inflammatory bowel disease, the data we hold shows insufficient reliable evidence to rate how well they work. That doesn't mean they don't help, only that the research isn't clear enough yet to say one way or the other.

The evidence, ingredient by ingredient Lipase Lactase Proteolytic Enzymes (proteases)

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lipase, lactase, and neutral protease are generally well tolerated when used as directed. One rare allergic reaction to lactase itself has been reported in a worker exposed to powdered lactase — actual supplement use carries little reported risk.

Proteolytic enzymes (the neutral protease here) are commonly used but may occasionally cause digestive upset or, rarely, allergic reactions. Regarding pregnancy and breastfeeding: lactase is likely safe, but lipase has little safety data in pregnancy so use only if your doctor advises it.

Neutral protease should be avoided in pregnancy unless prescribed, and there is limited data during breastfeeding — check with your healthcare provider before regular use in either case.

Side effects, ingredient by ingredient Lipase Lactase Proteolytic Enzymes (proteases)

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 3 matched ingredients has a documented medication interaction on file.

No interactions are documented in our data for the ingredients we could check. That said, we couldn't verify interaction data for amylase, cellulase, or digezyme — if you take any medications and want to be thorough, mention this product to your pharmacist or doctor.

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with strong clinical evidence behind its ingredients' uses. No medication interactions are currently documented, and safety information is well characterized.

If you have lactose intolerance, lactase in this product has good evidence behind it. For general digestive support, the evidence is less clear.

Because some ingredients' interaction data couldn't be verified and pregnancy/breastfeeding safety varies by enzyme, talk it over with your own doctor or pharmacist before starting, especially if you're pregnant, breastfeeding, or have a serious digestive condition.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 24, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Digestive Enzymes 75 mg, straight from the product label.

Brand Pure Prescriptions
Barcode (UPC) 852980001894
Net contents 90 Capsule(s)
Market status On market
Date entered into DSLD Jun 24, 2020
DSLD ID 228182
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Digestive Enzymes 75 mg by Pure Prescriptions, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
90
UPC/BARCODE
852980001894
IngredientAmount% DV
Amylase0 NP--
Lipase0 NP--
Lactase0 NP--
Cellulase0 NP--
Neutral Protease0 NP--
Digezyme75 mg--

Other ingredients: Rice Flour

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement take 1 or more capsules at mealtime or as recommended by a qualified healthcare professional.

Precautions

Read first: Children, women who are pregnant or nursing, and those being treated for a medical condition should consult a healthcare professional before using any supplement.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General Statements

Natural health solutions

75 mg /capsule

Formulation

Professional grade

Complete plant-based digestive support

FDA Statement of Identity

Dietary Supplement

Brand IP Statement(s)

DigeZyme is a registered trademark of Sabinsa Corporation.

See for yourself

Digestive Enzymes 75 mg by Pure Prescriptions label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Digestive Enzymes 75 mg by Pure Prescriptions

These are the 6 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Amylase

0 NP per serving

Lipase

No known
interactions
0 NP per serving

Lipase is a digestive enzyme that helps your body break down dietary fats. It is well established as part of prescription pancreatic enzyme therapy fo...

Lipase monograph & interactions

Lactase

No known
interactions
0 NP per serving

Lactase is a digestive enzyme supplement that helps people who lack enough natural lactase break down lactose, the sugar in milk and dairy. It can red...

Lactase monograph & interactions

Cellulase

0 NP per serving

Neutral Protease

No known
interactions
0 NP per serving

Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), tr...

Neutral Protease monograph & interactions

Digezyme

75 mg per serving

Other (inactive) ingredients: Rice Flour. These complete the product’s ingredient list but are not active constituents.

Interaction report

Digestive Enzymes 75 mg by Pure Prescriptions Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Digestive Enzymes 75 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Digestive Enzymes 75 mg, from the product label.

Pure Prescriptions

See all Pure Prescriptions products
Name
Pure Prescriptions, Inc.
Phone Number
1.800.860.9583
Web Address
www.PurePrescriptions.com
Pharmacist Counseling Corner

Digestive Enzymes 75 mg by Pure Prescriptions: Common Questions

Does Digestive Enzymes 75 mg by Pure Prescriptions interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Digestive Enzymes 75 mg. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Digestive Enzymes 75 mg contains 6 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this help with lactose intolerance?
Lactase, one of the six enzymes here, is effective for lactose intolerance. If that's your main concern, this product contains that ingredient.
Can I take this if I'm pregnant?
It depends on the enzyme. Lactase is likely safe, but lipase has little safety data in pregnancy and neutral protease should be avoided unless your doctor prescribes it. Check with your healthcare provider before starting.
Are there any side effects?
No adverse effects have been reported in adults for lipase or lactase in supplement form. Neutral protease is generally well tolerated but may rarely cause digestive upset or allergic reactions. One case of allergic reaction to lactase itself was reported in occupational exposure, not typical supplement use.
Does this work for indigestion?
The product contains enzymes like lipase and neutral protease that might help, but the data we hold shows insufficient reliable evidence to say how well they work for indigestion.
Is it safe to breastfeed while taking this?
Lactase is considered likely safe, but lipase and neutral protease have limited safety data during breastfeeding. Ask your doctor or pharmacist first before regular use.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Digestive Enzymes 75 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Digestive Enzymes 75 mg label
Sources

Sources & How We Checked

Digestive Enzymes 75 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lipase 1 reference
  1. Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed

See these in context on the Lipase monograph →

Lactase 1 reference
  1. Laukkanen A, Ruoppi P, Remes S, Koistinen T, Mäkinen-Kiljunen S. Lactase-induced occupational protein contact dermatitis and allergic rhinoconjunctivitis. Contact Dermatitis. 2007;57(2):89-93. PubMed

See these in context on the Lactase monograph →

Proteolytic Enzymes (proteases) 3 references
  1. Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
  2. Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
  3. Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed

See these in context on the Proteolytic Enzymes (proteases) monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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