Interactions on record — worth a quick check against your medications. Based on 4 of 12 ingredients. Check your meds →
Dietary supplement

DigestMore Fats & Proteins Ingredients & Drug Interactions

by Renew Life

DigestMore Fats & Proteins label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking DigestMore Fats & Proteins against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

DigestMore Fats & Proteins is a dietary supplement by Renew Life with 12 active ingredients. Its ingredients are commonly taken for lactose intolerance, gas and bloating after dairy, diarrhea from dairy foods.Based on those ingredients, 141 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Bromelain. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against DigestMore Fats & Proteins by Renew Life

Ask about any prescription or over-the-counter medication and we check it for interactions with DigestMore Fats & Proteins by Renew Life — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of DigestMore Fats & Proteins by Renew Life

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 12 active ingredients.
  • “Dairy Enzyme Blend” is a proprietary blend — the label gives one combined amount (1 mg) without saying how much of each component you get.
  • “Protein Enzyme Blend” is a proprietary blend — the label gives one combined amount (36 mg) without saying how much of each component you get.
  • “Fat Enzyme Blend” is a proprietary blend — the label gives one combined amount (21 mg) without saying how much of each component you get.

DigestMore contains 12 active ingredients — enzymes designed to break down fats, proteins, and carbohydrates to help with digestion. The product includes lactase (which helps digest milk sugar), bromelain (from pineapple), fungal and bacterial proteases and lipases (to break down proteins and fats), and various carbohydrate-digesting enzymes like amylase and diastase.

Several ingredients are grouped into blends — dairy enzyme, protein enzyme, fat enzyme, and carbohydrate enzyme blends — whose individual components are listed separately in the label. The capsule also contains maltodextrin and medium-chain triglycerides as inactive ingredients.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Support fat and protein digestion, reduce gas and bloating.
  • We looked for evidence on: Dyspepsia, Lactose intolerance, Indigestion, Flatulence.
  • The strongest evidence on file: Lactase is rated "Effective" for Lactose intolerance (Natural Medicines).
  • Also on file: Lipase is rated "Insufficient Reliable Evidence To Rate" for Dyspepsia.

Lactase is rated effective for lactose intolerance. The evidence isn't established in our data for lactase's use in prematurity or colic, and there's insufficient evidence for bromelain across the conditions we have on file — including hay fever, burns, and chronic venous insufficiency.

For the other active ingredients (the various proteases, lipases, and carbohydrate enzymes), effectiveness ratings are not available in the data we hold.

The evidence, ingredient by ingredient Lactase Proteolytic Enzymes (proteases) Bromelain Lipase

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 4 of the 4 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 4 of 4.
  • General safety write-ups exist for 4 of 4.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lactase is generally well tolerated when used as directed, though a rare case of allergic reaction (contact dermatitis and allergic rhinitis) has been reported in someone exposed to powdered lactase. Bromelain is generally well tolerated short-term, but long-term safety data is limited.

It may cause diarrhea, flatulence, gastric upset, or headache, and rarely can trigger allergic reactions including asthma if inhaled. The proteases are generally well tolerated for most adults but may cause digestive upset or allergic reactions.

Lipase has no reported adverse effects in adults, though serious gastrointestinal effects have occurred rarely in premature infants given recombinant lipase. During pregnancy, lactase is rated likely safe.

Bromelain, fungal protease, and acid protease should be avoided in pregnancy unless prescribed — the safety data doesn't support their use. There isn't enough safety data on lipase in pregnancy, so talk with your doctor first.

During breastfeeding, there's limited data for all enzymes; check with your healthcare provider before use.

Side effects, ingredient by ingredient Lactase Proteolytic Enzymes (proteases) Bromelain Lipase

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 4 matched ingredients can interact with medications — Bromelain.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 141 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take blood thinners or antiplatelet drugs (like warfarin or aspirin), or tetracycline antibiotics, run them through the medication checker on this page before starting DigestMore — bromelain poses a Moderate risk of increased bleeding with the first group and a Minor theoretical risk with the second.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product is an enzyme blend meant to help digest fats and proteins. If you take blood thinners, antiplatelet drugs, or tetracycline antibiotics, check with us or your doctor first — bromelain may increase bleeding risk or affect how your antibiotics work.

Talk to your pharmacist, especially if you're pregnant, breastfeeding, or have a serious digestive condition.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 5 of 12 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 27, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about DigestMore Fats & Proteins, straight from the product label.

Brand Renew Life
Net contents 90 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Jul 27, 2021
DSLD ID 250761
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for DigestMore Fats & Proteins by Renew Life, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
90
IngredientAmount% DV
Lactase0 NP--
Cellulase0 NP--
Alpha-Galactosidase0 NP--
Pectinase0 NP--
Dairy Enzyme Blend1 mg--
Beta Glucanase0 NP--
Protein Enzyme Blend36 mg--
Fungal Protease0 NP--
Peptidase0 NP--
Bromelain0 NP--
Acid Protease0 NP--
Fat Enzyme Blend21 mg--
Lipase Blend0 NP--
Carbohydrate & Plant Enzyme Blend6 mg--
Fungal Amylase0 NP--
Diastase0 NP--

Other ingredients: Maltodextrin, Capsule, Medium Chain Triglycerides

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Enzyme formula Take with meals to support fat and protein digestion Relieves occasional gas, bloating and indigestion

Quality, purity and potency guaranteed through expiration.

Ideal for diets high in fats and proteins Made with vegetarian capsules

Renew Life plant-based enzymes work with your digestive system to reduce occasional digestive discomforts and unlock the nutrient goodness in your foods.

FDA Statement of Identity

Enzyme Supplement

Suggested/Recommended/Usage/Directions

Directions: Take one (1) capsule with each meal.

Precautions

Contains: Soy, milk and wheat traces from fermentation media.

Keep out of reach of children.

Consult your physician prior to using this or any product if you are pregnant, nursing, taking any medication or have a medical condition.

Storage

Store at 77 degrees F (25 degrees C) or below.

Brand IP Statement(s)

Copyright 2018 Made in USA of global ingredients Patents: www.renewlife.com/patents

General Statements

Listen to your gut... you'll be glad you did. Did you know taking an enzyme can help improve your digestion? Many processed and cooked foods often lack the digestive enzymes found in their raw forms, so your body may have to work harder to break down and absorb nutrients.

At Renew Life, we're gut wellness pioneers with double decades of experience and innovation on our side to help keep you and your gut healthy and help you comfortably enjoy the foods you love. Visit RenewLife.com for help finding the right product for you.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formula

Contains a blend of naturally derived, plant-based enzymes

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

DigestMore Fats & Proteins by Renew Life label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

DigestMore Fats & Proteins label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in DigestMore Fats & Proteins by Renew Life

These are the 12 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Dairy Enzyme Blend

1 mg per serving

Protein Enzyme Blend

36 mg per serving

Fat Enzyme Blend

21 mg per serving

Carbohydrate & Plant Enzyme Blend

6 mg per serving
  • › Cellulase
  • › Alpha-Galactosidase
  • › Pectinase
  • › Beta Glucanase
  • › Fungal Amylase
  • › Diastase

Other (inactive) ingredients: Maltodextrin, Capsule, Medium Chain Triglycerides. These complete the product’s ingredient list but are not active constituents.

Interaction report

DigestMore Fats & Proteins by Renew Life Drug Interactions

Want to check YOUR meds against DigestMore Fats & Proteins?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
141Drugs
122 Moderate 19 Minor

Ingredients driving the most interactions

Bromelain 141

Individual Drug Interactions

The ingredients in DigestMore Fats & Proteins interact with 141 drugs. Click any drug to see the details.

1 of the 12 ingredients in DigestMore Fats & Proteins interact with drugs. Each result below shows which ingredient is responsible. Bromelain

Each ingredient & the kinds of drugs it affects

For each ingredient in DigestMore Fats & Proteins with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Bromelain2 drug types · 141 drugs

Anticoagulant/Antiplatelet Drugs

Bromelain may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
There is one case report of a patient experiencing minor bruising while taking bromelain with naproxen. Bromelain is thought to have antiplatelet activity. Whether this interaction is of concern with topical bromelain is unclear. Interference with coagulation of burn wounds has been reported in a patient receiving bromelain-based enzymatic debridement. However, observational research has found that topical bromelain debridement is not associated with increases or decreases in laboratory markers of coagulation when compared with surgical debridement.

Likelihood Possible Evidence D
Tetracycline Antibiotics

Theoretically, bromelain might increase levels of tetracycline antibiotics.
Laboratory research suggests that bromelain might increase the absorption of tetracycline antibiotics. However, a study in healthy adults reported no difference in tetracycline plasma levels when a 500 mg dose was taken with or without bromelain 80 mg.

Likelihood Possible Evidence B
Bromelain full monograph & interactions
The maker

Brand information

Manufacturer and brand details for DigestMore Fats & Proteins, from the product label.

Renew Life

Name
Renew Life Formulas, Inc.
City
Palm Harbor
State
FL
ZipCode
34683
Phone Number
1-800-830-1800
Web Address
www.renewlife.com
Pharmacist Counseling Corner

DigestMore Fats & Proteins by Renew Life: Common Questions

Does DigestMore Fats & Proteins by Renew Life interact with any medications?
Yes. Based on its ingredients, DigestMore Fats & Proteins has a known interaction with 141 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
DigestMore Fats & Proteins contains 12 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this help me digest dairy if I'm lactose intolerant?
Yes — lactase, one of the active ingredients here, is rated effective for lactose intolerance. It breaks down milk sugar so your gut can absorb it without bloating or discomfort.
Can I take this if I'm pregnant?
Lactase is rated likely safe in pregnancy, but bromelain and the proteases should be avoided unless your doctor prescribes them. There's also limited data on lipase in pregnancy, so ask your doctor or pharmacist for personalized advice.
What side effects might I experience?
Most people tolerate the enzymes well. Bromelain may cause diarrhea, flatulence, gastric upset, or headache. The proteases may cause digestive upset or allergic reactions. Rarely, allergic reactions to any of these enzymes can occur, including asthma if you inhale them.
Is this safe to use long-term?
Lactase is generally well tolerated with regular use. Bromelain has limited long-term safety data, so evidence on long-term use is not well established. For the other enzymes, we don't have detailed long-term safety information on file, so check with your doctor if you plan to use this regularly.
Does this product contain any fillers or additives?
The capsule contains maltodextrin and medium-chain triglycerides as inactive ingredients — these are excipients to make the capsule work, not active enzymes.
Can I take this while breastfeeding?
Safety data on these enzymes during breastfeeding is limited or not well studied. Talk with your healthcare provider before using this product while breastfeeding.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if DigestMore Fats & Proteins is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

DigestMore Fats & Proteins label
Go deeper

The Full Monographs Behind DigestMore Fats & Proteins’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Lactase

Lactase is a digestive enzyme supplement that helps people who lack enough natural lactase break down lactose, the sugar in milk and dairy. It can reduce gas, bloating, cramping, and diarrhe...

Read the full Lactase monograph → Herb & supplement monograph

Proteolytic Enzymes (proteases)

Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), trypsin, chymotrypsin, and pancreatin. Peo...

Read the full Proteolytic Enzymes (proteases) monograph → Herb & supplement monograph

Bromelain

Interacts with 141 drugs

Bromelain is a group of protein-digesting enzymes from pineapple that people take mainly for inflammation, swelling, and sinus problems. Some early studies are promising, but the overall evi...

Read the full Bromelain monograph → Herb & supplement monograph

Lipase

Lipase is a digestive enzyme that helps your body break down dietary fats. It is well established as part of prescription pancreatic enzyme therapy for people who cannot make enough of their...

Read the full Lipase monograph →
Sources

Sources & How We Checked

DigestMore Fats & Proteins's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 24 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lactase 1 reference
  1. Laukkanen A, Ruoppi P, Remes S, Koistinen T, Mäkinen-Kiljunen S. Lactase-induced occupational protein contact dermatitis and allergic rhinoconjunctivitis. Contact Dermatitis. 2007;57(2):89-93. PubMed

See these in context on the Lactase monograph →

Proteolytic Enzymes (proteases) 3 references
  1. Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
  2. Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
  3. Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed

See these in context on the Proteolytic Enzymes (proteases) monograph →

Bromelain 19 references
  1. Nettis E, Napoli G, Ferrannini A, Tursi A. IgE-mediated allergy to bromelain. Allergy 2001;56:257-8. PubMed
  2. Taussig SJ, Batkin S. Bromelain, the enzyme complex of pineapple (Ananas comosus) and its clinical application. An update. J Ethnopharmacol 1988;22:191-203.. PubMed
  3. Bradbrook ID, Morrison PJ, Rogers HJ. The effect of bromelain on the absorption of orally administered tetracycline. Br J Clin Pharmacol 1978;6:552-4. PubMed
  4. Bush TM, Rayburn KS, Holloway SW, et al. Adverse interactions between herbal and dietary substances and prescription medications: a clinical survey. Altern Ther Health Med 2007;13:30-5.
  5. Brien S, Lewith G, Walker AF, et al. Bromelain as an adjunctive treatment for moderate-to-severe osteoarthritis of the knee: a randomized placebo-controlled pilot study. QJM 2006;99:841-50. PubMed
  6. Mori S, Ojima Y, Hirose T, et al. The clinical effect of proteolytic enzyme containing bromelain and trypsin on urinary tract infection evaluated by double blind method. Acta Obstet Gynaecol Jpn 1972;19:147-53.
  7. Glaser D, Hilberg T. The influence of bromelain on platelet count and platelet activity in vitro. Platelets 2006;17:37-41. PubMed
  8. Heinicke R M, van der Wal L, Yokoyama M. Effect of bromelain (Ananase) on human platelet aggregation. Experientia 1972;28:844-5. PubMed
  9. Gailhofer, G., Wilders-Truschnig, M., Smolle, J., and Ludvan, M. Asthma caused by bromelain: an occupational allergy. Clin Allergy 1988;18(5):445-450. PubMed
  10. Mattei, O., Fabri, G., and Farina, G. [Occupational health experience regarding four cases of asthma due to bromelain (author's transl)]. Medicina del Lavoro 1979;70(5):404-409.
  11. Galleguillos, F. and Rodriguez, J. C. Asthma caused by bromelin inhalation. Clin Allergy 1978;8(1):21-24. PubMed
  12. Perez-Camo I, Quirce S, Duran MA, and et al. Latex allergy: evidence of cross-reactivity with papain and bromelain [abstract]. Allergy 1996;51(suppl 31):48.
  13. Martin GJ, Ehrenreich J, and Asbell N. Bromelain: pineapple proteases with anti-edema activity. Exp Med Surg 1962;20:227-247.
  14. Kasemsuk T, Saengpetch N, Sibmooh N, Unchern S. Improved WOMAC score following 16-week treatment with bromelain for knee osteoarthritis. Clin Rheumatol. 2016 Oct;35(10):2531-40. PubMed
  15. Kutlu Ö, DemirbaS A, Elmas ÖF, Güvenç U, Metin A. Fixed drug eruption: a new side effect of bromelain. Contact Dermatitis 2020. Online ahead of print. PubMed
  16. Shoham Y, Shapira E, Haik J, et al. Bromelain-based enzymatic debridement of chronic wounds: Results of a multicentre randomized controlled trial. Wound Repair Regen 2021;29(6):899-907. PubMed
  17. Pfister P, Garcia Wendel PD, Kim BS, et al. Coagulation side effects of enzymatic debridement in burned patients. Burns 2022. PubMed
  18. Hasham S, Riyat H, Fletcher A, O'Boyle CP, Alexander S. To bleed or not to bleed? Case series and discussion of haemorrhage risk with enzymatic debridement in burn injuries. Scars Burn Heal 2023;9:20595131231168333. PubMed
  19. Leelakanok N, Petchsomrit A, Janurai T, Saechan C, Sunsandee N. Efficacy and safety of bromelain: A systematic review and meta-analysis. Nutr Health 2023. PubMed

See these in context on the Bromelain monograph →

Lipase 1 reference
  1. Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed

See these in context on the Lipase monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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