No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

EPI-GH Ingredients & Drug Interactions

by Primeval Labs

Capsule Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

EPI-GH is a dietary supplement by Primeval Labs with 2 active ingredients. Its ingredients are commonly taken for muscle building and strength, bodybuilding 'prohormone' supplement, boosting androgen/dht levels.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of EPI-GH by Primeval Labs

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

EPI-GH contains two active ingredients: epiandrosterone and MK-677. Epiandrosterone is a hormone-related compound, and MK-677 is included to support the product's stated purposes.

The capsules also contain rice flour and gelatin as inactive ingredients.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Epiandrosterone's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: strength gains and muscle density.
  • We looked for evidence on: Athletic performance, Exercise-induced muscle damage, Muscle strength, Lean muscle mass, Body composition, Power output.
  • The closest evidence on file: Epiandrosterone is rated "Insufficient Reliable Evidence To Rate" for Athletic performance (Natural Medicines).
  • Also on file: Epiandrosterone is rated "Insufficient Reliable Evidence To Rate" for Muscle strength, Exercise-induced muscle damage.

The evidence we hold doesn't establish that epiandrosterone works for athletic performance, erectile dysfunction, muscle strength, sexual arousal, or obesity—the data simply isn't there to support any of these claims. We couldn't assess MK-677 either because we have no effectiveness data on file for it.

The evidence, ingredient by ingredient Epiandrosterone

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 0 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Epiandrosterone is a hormone-related supplement with limited safety data and a real potential for androgenic side effects (effects tied to male hormones)—that's why we flag it as one to be cautious with. The safety data advises against using it during pregnancy or while breastfeeding.

We have no safety information on file for MK-677. If you have any hormone-sensitive conditions, liver concerns, or are on any medications, talk with your pharmacist or doctor before starting.

Side effects, ingredient by ingredient Epiandrosterone

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for epiandrosterone. We could not check MK-677.

Even so, because this is a hormone-related supplement, run your exact medications—especially anything for blood sugar, hormones, or the liver—through the search tool on this page before you take it.

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. No medication interactions are currently documented, and some safety-information gaps remain.

This is a hormone-related product with incomplete safety data and no established effectiveness in our records. Anyone curious about it should check with their pharmacist first, especially if they're pregnant, breastfeeding, or have any liver or hormone-related health concerns.

Your pharmacist can help you weigh the unknowns.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 21, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about EPI-GH, straight from the product label.

Brand Primeval Labs
Net contents 60 Cap(s)
Market status On market
Date entered into DSLD Nov 21, 2018
DSLD ID 180673
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses No Claim
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for EPI-GH by Primeval Labs, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
IngredientAmount% DV
Epiandrosterone75 mg--
MK-67710 mg--

Other ingredients: Rice Flour, Gelatin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Strength gains Muscle density

FDA Statement of Identity

Dietary Supplement

See for yourself

EPI-GH by Primeval Labs label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in EPI-GH by Primeval Labs

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Epiandrosterone

No known
interactions
75 mg per serving

Epiandrosterone is a steroid-related compound (a metabolite of DHEA) sold as a 'prohormone' supplement, mostly for muscle building and athletic perfor...

Epiandrosterone monograph & interactions

MK-677

10 mg per serving

Other (inactive) ingredients: Rice Flour, Gelatin. These complete the product’s ingredient list but are not active constituents.

Interaction report

EPI-GH by Primeval Labs Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in EPI-GH. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for EPI-GH, from the product label.

Primeval Labs

See all Primeval Labs products
Name
Primeval Labs
Pharmacist Counseling Corner

EPI-GH by Primeval Labs: Common Questions

Does EPI-GH by Primeval Labs interact with any medications?
We do not currently list a known interaction for the mapped ingredients in EPI-GH. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
EPI-GH contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe to take while I'm pregnant or breastfeeding?
No. The safety data advises against epiandrosterone during pregnancy, and there's no safety data for it while breastfeeding. Hormone-related products should be avoided in both cases. Talk with your doctor or pharmacist before considering any supplement if you're pregnant or nursing.
Does this actually work for muscle strength or athletic performance?
The evidence we hold doesn't establish that epiandrosterone works for muscle strength, athletic performance, or any of the other claims on the label. We have no effectiveness data on file for MK-677 either. You'd want to discuss what the research actually shows with your pharmacist.
What's epiandrosterone, and why is it in here?
Epiandrosterone is a hormone-related compound—a prohormone meant to influence your body's hormone levels. It's included because the product is marketed for athletic performance and muscle, but it has limited safety data and real potential for androgenic side effects (effects related to male hormones).
What's MK-677?
MK-677 is the other active ingredient in this product. We don't hold interaction or effectiveness data for it, so we can't tell you what it does or how it interacts with medications. Your pharmacist may be able to help you find more information about it.
Are there any side effects I should know about?
Epiandrosterone is a hormone-related supplement with limited safety data and real potential for androgenic side effects. Because we have no adverse effect data on file for it or for MK-677, we can't give you a full picture. Talk with your pharmacist about what to watch for.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if EPI-GH is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

EPI-GH label
Sources

Sources & How We Checked

EPI-GH's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 1 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Epiandrosterone 1 reference
  1. Joseph JF, Parr MK. Synthetic androgens as designer supplements. Curr Neuropharmacol. 2015;13(1):89-100. PubMed

See these in context on the Epiandrosterone monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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