Interactions on record — worth a quick check against your medications. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

1-Andro Max V2 Ingredients & Drug Interactions

by Primeval Labs

1-Andro Max V2 label
See full label image
Tablet Or Pill Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking 1-Andro Max V2 against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

1-Andro Max V2 is a dietary supplement by Primeval Labs with 2 active ingredients. Its ingredients are commonly taken for muscle building, increasing strength, athletic performance.Based on those ingredients, 8 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are 1-Androsterone. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against 1-Andro Max V2 by Primeval Labs

Ask about any prescription or over-the-counter medication and we check it for interactions with 1-Andro Max V2 by Primeval Labs — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of 1-Andro Max V2 by Primeval Labs

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This product has 2 active ingredients. The main one is 1-androsterone, a prohormone that your body converts into testosterone-like androgens after you ingest it.

The other active ingredient is 6,7 dihydroxybergamottin. The rest are inactive ingredients — binders, fillers, and capsule material like microcrystalline cellulose, dicalcium phosphate, and magnesium stearate.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see 1-androsterone's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: lean muscle mass and strength building.
  • We looked for evidence on: Athletic performance, muscle strength, body composition, lean mass.
  • The closest evidence on file: 1-androsterone is rated "Insufficient Reliable Evidence To Rate" for Athletic performance (Natural Medicines).

The evidence for 1-androsterone and athletic performance is insufficient — we don't have reliable data to say whether it works for that goal. The safety testing on this compound is also very limited, so we can't say much about what it actually does in real use.

The evidence, ingredient by ingredient 1-androsterone

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 0 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

This is a hormonal compound with real health risks and limited safety testing. The most common side effects reported are changes in cholesterol (LDL goes up, HDL goes down), liver enzyme elevations, and kidney problems.

In studies lasting just 4 weeks, people showed significant drops in kidney function (GFR dropped below normal range, around 16 points) and rises in a marker of kidney stress, even though creatinine itself stayed in normal range. That's concerning for potential kidney impairment.

Do not use this during pregnancy — it's a hormone-altering compound and safety data advises against it. Avoid while breastfeeding too, because we don't know the hormonal risks to your baby.

Side effects, ingredient by ingredient 1-androsterone

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — 1-androsterone.
  • The most serious interaction on file is rated Moderate.
  • For scale: 8 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your pharmacist if you take testosterone or any testosterone-based hormone therapy (patches, injections, gels, or creams). 1-androsterone can add to testosterone's effects and raise the risk of mood, heart, kidney, and liver problems.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and some safety-information gaps remain.

This is a hormone-based supplement with documented effects on cholesterol, liver, and kidney function in short-term studies. If you take testosterone or any hormonal medication, you need to check with your pharmacist before using it.

Even if you don't, the limited safety data means talking with your doctor first is a smart move — especially if you have liver, kidney, or heart concerns.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 21, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about 1-Andro Max V2, straight from the product label.

Brand Primeval Labs
Net contents 60 Tab(s)
Market status On market
Date entered into DSLD Nov 21, 2018
DSLD ID 172307
Product type Non-nutrient/non-botanical
Supplement form Tablet Or Pill
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for 1-Andro Max V2 by Primeval Labs, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
2 Tablet(s)
Servings per container
60
IngredientAmount% DV
1-Androsterone100 mg--
6,7 Dihydroxybergamottin15 mg--

Other ingredients: Phospholipids from non-GMO Soy Lecithin, Microcrystalline Cellulose, Dicalcium Phosphate, Hydroxy Propyl Beta Cyclodextrin, Polyvinylpolypyrrolidone, Silica, Colloidal Anhydrous, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Lean mass / Muscle builder

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions for 1-Andro Max v2: As a dietary supplement, take 1-2 tablets twice daily. Do not use 1-Andro Max v2 for longer than 8 weeks continuously. Take at least 8 weeks off between cycles.

Precautions

Warnings: Read entire label and obtain clearance from a licensed healthcare practitioner before use. This product is to be used by healthy adults only.

Do not use if you have or could develop any medical condition or are taking any prescription drugs. Do not use if you are pregnant, nursing, or may become pregnant.

Do not use more than the recommended dosage. Discontinue use and consult a physician if any adverse reactions occur.

As with all supplements, keep out of reach of children and animals.

Storage

Keep lid tightly closed and in cool, dry place.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

1-Andro Max V2 by Primeval Labs label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

1-Andro Max V2 label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in 1-Andro Max V2 by Primeval Labs

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

1-Androsterone

Interacts with
8 drugs
100 mg per serving

1-Androsterone (1-DHEA or 1-Andro) is a synthetic prohormone marketed to bodybuilders for muscle and strength gains, but it has not been proven safe o...

1-Androsterone monograph & interactions

6,7 Dihydroxybergamottin

15 mg per serving

Other (inactive) ingredients: Phospholipids from non-GMO Soy Lecithin, Microcrystalline Cellulose, Dicalcium Phosphate, Hydroxy Propyl Beta Cyclodextrin, Polyvinylpolypyrrolidone, Silica, Colloidal Anhydrous, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

1-Andro Max V2 by Primeval Labs Drug Interactions

Want to check YOUR meds against 1-Andro Max V2?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
8Drugs
8 Moderate

Ingredients driving the most interactions

1-Androsterone 8

Individual Drug Interactions

The ingredients in 1-Andro Max V2 interact with 8 drugs. Click any drug to see the details.

1 of the 2 ingredients in 1-Andro Max V2 interact with drugs. Each result below shows which ingredient is responsible. 1-Androsterone

Each ingredient & the kinds of drugs it affects

For each ingredient in 1-Andro Max V2 with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

1-Androsterone1 drug type · 8 drugs

Testosterone

Theoretically, taking 1-androsterone with testosterone might increase the risk for additive adverse effects such as mood disturbances and cardiovascular, kidney, or liver problems.
1-Androsterone is converted to 1-testosterone and other androgens upon ingestion.

Likelihood Possible Evidence D
1-Androsterone full monograph & interactions
The maker

Brand information

Manufacturer and brand details for 1-Andro Max V2, from the product label.

Primeval Labs

See all Primeval Labs products
Name
Primeval Labs
Pharmacist Counseling Corner

1-Andro Max V2 by Primeval Labs: Common Questions

Does 1-Andro Max V2 by Primeval Labs interact with any medications?
Yes. Based on its ingredients, 1-Andro Max V2 has a known interaction with 8 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
1-Andro Max V2 contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
No. The safety data advises against using this during pregnancy because it alters hormones. Avoid while breastfeeding too — we don't know what hormonal risks it could pose to your baby.
What are the most common side effects?
The most reported are changes in cholesterol (LDL cholesterol goes up, HDL goes down), liver enzyme elevations, and kidney dysfunction. Even in short studies, kidney function markers showed significant drops, which could signal early kidney problems.
Does this actually improve athletic performance?
The evidence isn't established in our data — we don't have reliable research to say whether it works for that.
What does 1-androsterone do in my body?
It's a prohormone that converts to testosterone and other hormone-like compounds once you ingest it. That's why it can affect your mood, heart, kidneys, and liver.
How long can I safely take this?
We don't have safety data on long-term use. The only studies we have are 4 weeks long and already showed significant changes in cholesterol and kidney function — talk to your doctor about whether it's right for you at all.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

1-Andro Max V2 label
Go deeper

The Full Monographs Behind 1-Andro Max V2’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

1-androsterone

Interacts with 8 drugs

1-Androsterone (1-DHEA or 1-Andro) is a synthetic prohormone marketed to bodybuilders for muscle and strength gains, but it has not been proven safe or effective in quality human studies. It...

Read the full 1-androsterone monograph →
Sources

Sources & How We Checked

1-Andro Max V2's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 2 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

1-androsterone 2 references
  1. Parr MK, Opfermann G, Geyer H, et al. Seized designer supplement named "1-Androsterone": identification as 3ß-hydroxy-5a-androst-1-en-17-one and its urinary elimination. Steroids 2011;76(6):540-7.
  2. Granados J, Gillum TL, Christmas KM, et al. Prohormone supplement 3b-hydroxy-5a-androst-1-en-17-one enhances resistance training gains but impairs user health. J Appl Physiol (1985). 2014;116(5):560-9.

See these in context on the 1-androsterone monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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