Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Halodrol Ingredients & Drug Interactions

by HTP Hi-Tech Pharmaceuticals

Halodrol label
See full label image
Tablet Or Pill Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Halodrol against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Halodrol is a dietary supplement by HTP Hi-Tech Pharmaceuticals with 5 active ingredients. Its ingredients are commonly taken for muscle building and athletic performance, boosting testosterone or androgen levels, supporting libido.Based on those ingredients, 776 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Androstenolone Acetate, Rhaponticum carthamoides 100:1 extract, Androsterone. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Halodrol by HTP Hi-Tech Pharmaceuticals

Ask about any prescription or over-the-counter medication and we check it for interactions with Halodrol by HTP Hi-Tech Pharmaceuticals — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Halodrol by HTP Hi-Tech Pharmaceuticals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 5 active ingredients.
  • “Proprietary Anabolic Blend” is a proprietary blend — the label gives one combined amount (250 mg) without saying how much of each component you get.

Halodrol contains five active ingredients. The first three—Androsterone, 1-Androstene-3b-ol, 17-one, and 4-Androstene-3b-ol, 17-one—are androgenic prohormones (hormone-like compounds your body may convert to testosterone and related androgens).

The fourth is Androstenolone Acetate, a DHEA-derived hormone. The fifth is Rhaponticum carthamoides, a plant extract.

These are supported by inactive ingredients including cellulose, phosphatidylcholine, and food colorings.

Does it work?

Leans against
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Leans against

The strongest graded evidence we hold for the stated purpose leans against a benefit.

Why this rating?
  • The label markets this product for: muscle building and athletic performance enhancement.
  • We looked for evidence on: Athletic performance, Exercise-induced muscle damage, Muscle strength, Physical performance, Lean mass gain, Strength development — and 2 related terms.
  • The closest evidence on file: Dhea is rated "Possibly Ineffective" for Muscle strength (Natural Medicines).
  • Also on file: Dhea is rated "Possibly Ineffective" for Physical performance.
  • Also on file: Dhea is rated "Insufficient Reliable Evidence To Rate" for Athletic performance, Exercise-induced muscle damage.

The evidence for Halodrol's ingredients is limited. Androsterone, the two androsterone compounds, and the maral root extract all have insufficient reliable evidence to support claims about athletic performance, fatigue, sexual function, or obesity.

Androstenolone Acetate (DHEA) shows possibly effective evidence for depression and aging skin, and likely effective evidence for vaginal atrophy, but these uses fall outside the product's apparent athletic focus.

The evidence, ingredient by ingredient Androsterone 1-androsterone 4-androsterone Dhea Maral Root

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 4 of the 5 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 4 of 5.
  • General safety write-ups exist for 5 of 5.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

These are controlled anabolic-androgenic steroids and hormone compounds with real safety concerns and limited human testing. Androsterone is possibly unsafe orally, with concern for serious heart and liver injury.

The other prohormones carry similar risks: the product facts note concerns for stroke, kidney failure, and liver injury. One prohormone study reported significant drops in cholesterol (both the protective kind and the harmful kind) and signs of kidney impairment within four weeks.

DHEA-induced mood changes, acne, insomnia, and in females, masculinization effects (voice deepening, facial hair, irregular periods) have been reported. All active ingredients are unsafe or possibly unsafe in pregnancy and while breastfeeding; do not use if you are pregnant or nursing.

Side effects, ingredient by ingredient Androsterone 1-androsterone 4-androsterone Dhea Maral Root

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 5 of the 5 matched ingredients can interact with medications — Dhea, Maral Root, 1-androsterone, 4-androsterone, Androsterone.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 777 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your pharmacist if you take testosterone or other androgenic drugs, antidepressants (especially SSRIs), blood thinners or antiplatelet drugs like aspirin or warfarin, drugs metabolized by the liver enzyme CYP3A4 (a very large category), triazolam (Halcion) for sleep, estrogen-blocking cancer medications like tamoxifen or aromatase inhibitors, fulvestrant for cancer, or are due for a tuberculosis vaccine.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with graded evidence leaning against its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Halodrol is marketed as a sports supplement but contains potent androgenic and hormonal compounds with serious cardiovascular, liver, and kidney risks and minimal safety data in humans. Anyone considering it should talk with a doctor or pharmacist first, especially if taking medications.

It is not appropriate during pregnancy or breastfeeding.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 5 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 21, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Halodrol, straight from the product label.

Brand HTP Hi-Tech Pharmaceuticals
Barcode (UPC) 811836023008
Net contents 30 Tablet(s)
Market status On market
Date entered into DSLD Nov 21, 2020
DSLD ID 239453
Product type Other Combinations
Supplement form Tablet Or Pill
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Halodrol by HTP Hi-Tech Pharmaceuticals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
1 Tablet(s)
Servings per container
30
UPC/BARCODE
811836023008
IngredientAmount% DV
Androsterone0 NP--
Proprietary Anabolic Blend250 mg--
1-Androstene-3b-ol, 17-one0 NP--
4-Androstene-3b-ol, 17-one0 NP--
Androstenolone Acetate0 NP--
Rhaponticum carthamoides 100:1 extract0 NP--

Other ingredients: Microcrystalline Cellulose, Phosphatidylcholine, Hydroxypropyl Beta Cyclodextrin, Phytosterols, Magnesium Stearate, Silica, FD&C Blue #2, FD&C Yellow #5

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Maximal muscle myotropic developer Bodybuilding's most anabolically-potent, single-dose tablet! Amino Acid retention catalyst-enhances protein synthesis Natural anabolic and anti-proteolytic formulation Boost testosterone levels and enhance athletic performance

Made in the USA from domestic and international ingredients.

Halodrol is the latest evolution of the legendary Halodrol, made famous over a decade ago. Hi-Tech Pharmaceuticals commissioned the brightest scientific minds to develop a worthy successor to this widely popular product. The goal was to develop an even more potent and effective formula that would be worthy of sporting the Halodrol namesake. Hi-Tech is proud to introduce the new Halodrol, a patented, cutting-edge legal anabolic agent that is undeniable the most scientifically advanced and potent product in its class. Halodrol derives its powerful anabolic effects primarily from patented naturally occurring DHEA derivatives. These compounds provide the body with intense myotropic growth via enhancement of key bodily processes shown to upregulate Androgen Receptor activation, protein synthesis, and net nitrogen retention. Halodrol provides these potent muscle building compounds at the precise levels shown to maximize size, strength, & power output, giving you everything needed to take your gains to entirely new heights. To ensure Halodrol provides you with the results you demand, each tablet is infused with a dual-phase delivery system, systematically designed to allow the active components to bypass stomach & liver degradation, allowing for never-before-seen bioavailability and absorption. This novel delivery system is what makes Halodrol capable of providing you with significantly higher blood hormone levels, resulting in unparalleled gains when compared to absolutely anything else available on the market.

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take one tablet 30 minutes prior to training. On non-training days take one tablet in the morning or afternoon. Do not exceed 2 per day.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Brand IP Statement(s)

2018 Hi-Tech Pharmaceuticals Inc. - All rights reserved.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Halodrol by HTP Hi-Tech Pharmaceuticals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Halodrol label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Halodrol by HTP Hi-Tech Pharmaceuticals

These are the 5 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Other (inactive) ingredients: Microcrystalline Cellulose, Phosphatidylcholine, Hydroxypropyl Beta Cyclodextrin, Phytosterols, Magnesium Stearate, Silica, FD&C Blue #2, FD&C Yellow #5. These complete the product’s ingredient list but are not active constituents.

Interaction report

Halodrol by HTP Hi-Tech Pharmaceuticals Drug Interactions

Want to check YOUR meds against Halodrol?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
776Drugs
771 Moderate 5 Minor

Ingredients driving the most interactions

Androstenolone Acetate 776
Rhaponticum carthamoides 100:1 extract 122
Androsterone 9
1-Androstene-3b-ol, 17-one 8
4-Androstene-3b-ol, 17-one 8

Individual Drug Interactions

The ingredients in Halodrol interact with 776 drugs. Click any drug to see the details.

5 of the 5 ingredients in Halodrol interact with drugs. Each result below shows which ingredient is responsible. Androstenolone Acetate Rhaponticum carthamoides 100:1 extract Androsterone 1-Androstene-3b-ol, 17-one 4-Androstene-3b-ol, 17-one

Each ingredient & the kinds of drugs it affects

For each ingredient in Halodrol with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Androstenolone Acetate10 drug types · 776 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, DHEA might increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Human and laboratory research show that DHEA and DHEA-S can inhibit platelet aggregation.

Likelihood Possible Evidence D
Antidepressant Drugs

Theoretically, DHEA might increase the risk of psychiatric adverse events when used with antidepressants.
In a human case report, the use of a selective serotonin reuptake inhibitor (SSRI) with DHEA caused a manic episode. Concern for this interaction may be greater in younger individuals with higher baseline DHEA levels.

Likelihood Possible Evidence D
Aromatase Inhibitors

Theoretically, DHEA might interfere with the clinical effects of aromatase inhibitors.
DHEA is a potent estrogen agonist, which may antagonize the anti-estrogen activity of aromatase inhibitors.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, DHEA might increase the levels of drugs metabolized by CYP3A4.
Some preliminary evidence shows that DHEA may inhibit CYP3A4; however, the clinical significance of this potential interaction is not known.

Likelihood Possible Evidence D
Fulvestrant (Faslodex)

Theoretically, DHEA might interfere with the anti-estrogen effects of fulvestrant.
DHEA is a potent estrogen agonist. Some research shows that it can overcome the estrogen receptor antagonist action of fulvestrant in estrogen-receptor positive cancer cells.

Likelihood Possible Evidence D
Tamoxifen (Nolvadex)

Theoretically, DHEA might interfere with the anti-estrogen effects of tamoxifen.
DHEA is a potent estrogen agonist. Some research shows that it can overcome the estrogen receptor antagonist activity of tamoxifen in estrogen-receptor positive cancer cells.

Likelihood Possible Evidence D
Triazolam (Halcion)

DHEA can increase blood levels of triazolam.
Administration of DHEA 200 mg daily for two weeks was shown to inhibit the cytochrome P450 3A4 (CYP3A4) metabolism of triazolam. This inhibition appears to be due to DHEA-S, rather than DHEA.

Likelihood Probable Evidence D
Tuberculosis Vaccine

DHEA might reduce the effectiveness of the tuberculosis vaccine.
Animal research shows that high doses of DHEA can reduce the efficacy of the Bacillus Calmette-Guérin (BCG) tuberculosis vaccine.

Likelihood Possible Evidence D
Estrogens

Theoretically, DHEA might increase the effects and adverse effects of estrogen therapy.
DHEA is a precursor to estrogen and androgen and is metabolized into those substances. In clinical research, DHEA supplements increase the levels of these hormones. Also, in clinical research, estrogen-progestin oral contraceptives and conjugated estrogens reduce blood levels of DHEA and DHEA-S. The clinical significance of these findings is unclear.

Likelihood Possible Evidence D
Testosterone

Theoretically, DHEA might increase the effects and side effects of testosterone therapy.
DHEA is a precursor to estrogen and androgen and is metabolized into those substances. In clinical research, DHEA supplements increase the levels of these hormones. The clinical significance of these findings is unclear.

Likelihood Possible Evidence D
Androstenolone Acetate full monograph & interactions

Rhaponticum carthamoides 100:1 extract1 drug type · 122 drugs

Anticoagulant/Antiplatelet Drugs

In vitro research shows that maral root tincture can reduce platelet aggregation. Theoretically, maral root might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs. Some of these drugs include aspirin, clopidogrel (Plavix), nonsteroidal anti-inflammatory drugs (NSAIDs) such as diclofenac (Voltaren, Cataflam, others), ibuprofen (Advil, Motrin, others), naproxen (Anaprox, Naprosyn, others), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, warfarin (Coumadin), and others.

Likelihood Possible Evidence D
Rhaponticum carthamoides 100:1 extract full monograph & interactions

Androsterone1 drug type · 9 drugs

Androgens

Androsterone, as an androgenic hormone, may interact with other androgenic drugs, such as testosterone, due to their similar mechanisms of action. Both androsterone and testosterone bind to androgen receptors in various tissues throughout the body, leading to similar physiological effects related to the development and maintenance of male secondary sexual characteristics. When taken together, these compounds can potentially amplify these effects, leading to an increased risk of androgenic side effects, such as acne, hair loss, and changes in libido. Additionally, combining androsterone with testosterone or other androgenic drugs may also affect hormone levels and balance in the body, potentially leading to hormonal imbalances or disruptions in the endocrine system.

Likelihood Possible Evidence C
Androsterone full monograph & interactions

1-Androstene-3b-ol, 17-one1 drug type · 8 drugs

Testosterone

Theoretically, taking 1-androsterone with testosterone might increase the risk for additive adverse effects such as mood disturbances and cardiovascular, kidney, or liver problems.
1-Androsterone is converted to 1-testosterone and other androgens upon ingestion.

Likelihood Possible Evidence D
1-Androstene-3b-ol, 17-one full monograph & interactions

4-Androstene-3b-ol, 17-one1 drug type · 8 drugs

Testosterone

4-Androsterone is purportedly converted to testosterone and other androgens upon ingestion. Theoretically, taking 4-androsterone with testosterone may increase the risk for additive adverse effects such as mood disturbances and cardiovascular, kidney, or liver problems.

Likelihood Possible Evidence D
4-Androstene-3b-ol, 17-one full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Halodrol, from the product label.

HTP Hi-Tech Pharmaceuticals

See all HTP Hi-Tech Pharmaceuticals products
Name
Hi-Tech Pharmaceuticals
Street Address
6015-B Unity Drive
City
Norcross
State
GA
Phone Number
1.888.855.7919
Web Address
www.hitechpharma.com
Pharmacist Counseling Corner

Halodrol by HTP Hi-Tech Pharmaceuticals: Common Questions

Does Halodrol by HTP Hi-Tech Pharmaceuticals interact with any medications?
Yes. Based on its ingredients, Halodrol has a known interaction with 776 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Halodrol contains 5 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is Halodrol legal?
Androsterone, one of the main ingredients, is a controlled anabolic-androgenic steroid that is illegal to sell as a dietary supplement in the U.S. The product's legal status is problematic.
Can I take this if I'm pregnant or breastfeeding?
No. All the active ingredients are unsafe or possibly unsafe during pregnancy—androgenic hormones can harm a developing baby. Do not use while breastfeeding either, as the hormonal effects on an infant are unknown and potentially harmful.
What are the main side effects I should watch for?
Serious concerns include heart disease, liver injury, kidney problems, and stroke. More common effects reported include acne, headache, insomnia, mood changes, and nausea. In women, masculinization can occur (voice deepening, facial hair, irregular periods). One study showed significant drops in protective cholesterol and early signs of kidney impairment within four weeks.
Will this help my athletic performance?
The evidence isn't there. Both the athletic performance claims lack reliable evidence to support them in the data we hold. You're taking serious health risks for unproven benefit.
Why does it have so many drug interactions?
Because these are hormone-like compounds that affect your body's hormone system and how your liver processes drugs. Hormones and prohormones influence everything from mood to blood clotting to how fast your liver breaks down medications, which is why the interaction list is so long.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Halodrol is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Halodrol label
Go deeper

The Full Monographs Behind Halodrol’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Androsterone

Interacts with 9 drugs

Androsterone is a natural androgenic steroid hormone made in the body, but supplement versions are classified as anabolic-androgenic steroids and are banned from U.S. dietary supplements und...

Read the full Androsterone monograph → Herb & supplement monograph

1-androsterone

Interacts with 8 drugs

1-Androsterone (1-DHEA or 1-Andro) is a synthetic prohormone marketed to bodybuilders for muscle and strength gains, but it has not been proven safe or effective in quality human studies. It...

Read the full 1-androsterone monograph → Herb & supplement monograph

4-androsterone

Interacts with 8 drugs

4-Androsterone (sometimes called 4-DHEA) is a lab-made prohormone marketed to bodybuilders as a way to raise testosterone and build muscle, but human studies are very limited and it carries...

Read the full 4-androsterone monograph → Herb & supplement monograph

Dhea

Interacts with 776 drugs

DHEA is a natural hormone that the body makes and that declines with age, and it is sold as a supplement claiming many benefits. The evidence is mixed and limited for most uses, and because...

Read the full Dhea monograph → Herb & supplement monograph

Maral Root

Interacts with 122 drugs

Maral Root (Rhaponticum carthamoides) is a Siberian herb used as an 'adaptogen' and is popular among athletes for stamina and muscle building, largely because it contains plant compounds cal...

Read the full Maral Root monograph →
Sources

Sources & How We Checked

Halodrol's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 106 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Androsterone 1 reference
  1. Joseph JF, Parr MK. Synthetic androgens as designer supplements. Curr Neuropharmacol. 2015;13(1):89-100. PubMed

See these in context on the Androsterone monograph →

1-androsterone 2 references
  1. Parr MK, Opfermann G, Geyer H, et al. Seized designer supplement named "1-Androsterone": identification as 3ß-hydroxy-5a-androst-1-en-17-one and its urinary elimination. Steroids 2011;76(6):540-7.
  2. Granados J, Gillum TL, Christmas KM, et al. Prohormone supplement 3b-hydroxy-5a-androst-1-en-17-one enhances resistance training gains but impairs user health. J Appl Physiol (1985). 2014;116(5):560-9.

See these in context on the 1-androsterone monograph →

4-androsterone 3 references
  1. Anabolic Steroids and Other Appearance and Performance Enhancing Drugs (APEDs) — NIH National Institute on Drug Abuse Source
  2. Dietary Supplements for Exercise and Athletic Performance — NIH Office of Dietary Supplements Source
  3. DHEA — MedlinePlus Source

See these in context on the 4-androsterone monograph →

Dhea 98 references
  1. Frye RF, Kroboth PD, Folan MM, et al. Effect of DHEA on CYP3A-mediated metabolism of triazolam. Clin Pharmacol Ther 2000;67:109 (abstract PI-82).
  2. Kuritzky L. DHEA: Science or wishful thinking? Hosp Pract 1998;33:85-6. PubMed
  3. Van Vollenhoven RF, Morabito LM, Engleman EG, et al. Treatment of systemic lupus erythematosus with dehydroepiandrosterone: 50 patients treated up to 12 months. J Rheumatol 1998;25:285-9.
  4. Van Vollenhoven RF, Engleman EG, McGurie JL. Dehydroepiandrosterone in Systemic Lupus Erythematosus. Arth Rheum 1995;38:1826-31. DOI
  5. Ebeling P, Koivisto VA. Physiological importance of dehydroepiandrosterone. Lancet 1994;343:1479-81. PubMed
  6. Yen SS, Morales AJ, Khorram O. Replacement of DHEA in aging men and women. Potential remedial effects. Ann N Y Acad Sci 1995;774:128-42. PubMed
  7. Labrie F, Diamond P, Cusan L, et al. Effect of 12 month dehydroepiandrosterone replacement therapy on bone, vagina, and endometrium in postmenopausal women. J Clin Endocrinol Metab 1997;82:3498-505. PubMed
  8. Casson PR, Faquin LC, Stentz FB. Replacement of dehydroepiandrosterone enhances T-lymphocyte insulin binding in postmenopausal women. (abstract) Fertil Steril 1995;63:1027-31. DOI
  9. Morales AJ, Haubrich RH, Hwang JY, et al. The effect of six months treatment with a 100 mg daily dose of dehydroepiandrosterone (DHEA) on circulating sex steroids, body composition and muscle strength in age-advanced men and women. Clin Endocrinol (Oxf)1 PubMed
  10. Arlt W, Justl H, Callies F, et al. Oral dehydroepiandrosterone for adrenal androgen replacement: pharmacokinetics and peripheral conversion to androgens and estrogens in young healthy females after dexamethasone suppression. [Abstract] J Clin Endocrinol PubMed
  11. Kline MD, Jaggers ED. Mania onset while using dehydroepiandrosterone (letter). Am J Psychiatry 1999;156:971. PubMed
  12. Callies F, Arlt W, Siekmann L, et al. Influence of oral dehydroepiandrosterone (DHEA) on urinary steroid metabolites in males and females. Steroids 2000;65:98-102. PubMed
  13. Markowitz JS, Carson WH, Jackson CW. Possible dihydroepiandrosterone-induced mania. Biol Psychiatry 1999;45:241-2. PubMed
  14. Stoll BA. Dietary supplements of dehydroepiandrosterone in relation to breast cancer risk. Eur J Clin Nutr 1999;53:771-5. PubMed
  15. Dean CE. Prasterone (DHEA) and mania. Ann Pharmacother 2000;34:1419-22. PubMed
  16. Himmel PB, Seligman TM. A Pilot Study Employing Dehydroepiandrosterone (DHEA) in the Treatment of Chronic Fatigue Syndrome. [Abstract]. J Clin Rheumatol 1999:5:56-9. PubMed
  17. Hunt PJ, Gurnell EM, Huppert FA, et al. Improvement in mood and fatigue after dehydroepiandrosterone replacement in Addison's disease in a randomized, double blind trial. J Clin Endocrinol Metab 2000;85:4650-6.. PubMed
  18. Johannsson G, Burman P, Wiren L, et al. Low dose dehydroepiandrosterone affects behavior in hypopituitary androgen-deficient women: a placebo-controlled trial. J Clin Endocrinol Metab 2002;87:2046-52. PubMed
  19. Calhoun KE, Pommier RF, Muller P, et al. Dehydroepiandrosterone sulfate causes proliferation of estrogen receptor-positive breast cancer cells despite treatment with fulvestrant. Arch Surg 2003;138:879-83.. PubMed
  20. Morris KT, Toth-Fejel S, Schmidt J, et al. High dehydroepiandrosterone-sulfate predicts breast cancer progression during new aromatase inhibitor therapy and stimulates breast cancer cell growth in tissue culture: a renewed role for adrenalectomy. Surgery PubMed
  21. Calhoun K, Pommier R, Cheek J, et al. The effect of high dehydroepiandrosterone sulfate levels on tamoxifen blockade and breast cancer progression. Am J Surg 2003;185:411-5.. PubMed
  22. Stomati M, Monteleone P, Casarosa E, et al. Six-month oral dehydroepiandrosterone supplementation in early and late postmenopause. Gynecol Endocrinol 2000;14:342-63.. PubMed
  23. Petri MA, Mease PJ, Merrill JT, et al. Effects of prasterone on disease activity and symptoms in women with active systemic lupus erythematosus. Arthritis Rheum 2004;50:2858-68. PubMed
  24. Villareal DT, Holloszy JO, Kohrt WM. Effects of DHEA replacement on bone mineral density and body composition in elderly women and men. Clin Endocrinol (Oxf) 2000;53:561-8. PubMed
  25. Acacio BD, Stanczyk FZ, Mullin P, et al. Pharmacokinetics of dehydroepiandrosterone and its metabolites after long-term daily oral administration to healthy young men. Fertil Steril 2004;81:595-604. PubMed
  26. Petri MA, Lahita RG, Van Vollenhoven RF, et al. Effects of prasterone on corticosteroid requirements of women with systemic lupus erythematosus: a double-blind, randomized, placebo-controlled trial. Arthritis Rheum 2002;46:1820-9. PubMed
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Maral Root 2 references
  1. Koleckar V, Brojerova E, Rehakova Z, et al. In vitro antiplatelet activity of flavonoids from Leuzea carthamoides. Drug Chem Toxicol 2008;31(1):27-35.
  2. Ryan ED, Gerstner GR, Mota JA, et al. The Acute Effects of a Multi-Ingredient Herbal Supplement on Performance Fatigability: A Double-Blind, Randomized, and Placebo-Controlled Trial. J Diet Suppl 2021;18(5):507-516. PubMed

See these in context on the Maral Root monograph →

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