Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Andriol Ingredients & Drug Interactions

by HTP Hi-Tech Pharmaceuticals

Andriol label
See full label image
Tablet Or Pill Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Andriol against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Andriol is a dietary supplement by HTP Hi-Tech Pharmaceuticals with 1 active ingredient. Its ingredients are commonly taken for muscle building, strength and athletic performance, boosting testosterone.Based on those ingredients, 8 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Androst-4-en-3beta-ol-17-one undecanoate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Andriol by HTP Hi-Tech Pharmaceuticals

Ask about any prescription or over-the-counter medication and we check it for interactions with Andriol by HTP Hi-Tech Pharmaceuticals — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Andriol by HTP Hi-Tech Pharmaceuticals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Andriol contains one active ingredient: 4-androsterone undecanoate, a prohormone that your body may break down into testosterone and related androgens. The tablet also holds several inactive ingredients—microcrystalline cellulose, various medium-chain fatty acids (caprylic, caproic, capric, and lauric acids), beta-cyclodextrin, phytosterols, and silica—which serve as fillers, binders, and absorption enhancers.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: testosterone replenishment and androgen elevation.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

The product facts we have don't include effectiveness ratings for 4-androsterone. That means the evidence for whether it actually works as intended isn't established in the data we hold.

If you're considering this product, that's worth discussing with us or your doctor before you buy.

The evidence, ingredient by ingredient 4-androsterone

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Here's what matters: prohormones like this one can disrupt your natural hormone balance, put stress on your liver, and shift your cholesterol levels—and the long-term safety picture isn't well studied. The ingredient may theoretically cause serious side effects similar to anabolic steroids, including stroke, kidney failure, and liver injury, though detailed adverse effect data is limited.

Don't use Andriol if you're pregnant—androgenic hormones can harm a developing baby. If you're breastfeeding, avoid it too; the hormonal effects on an infant aren't known and could be harmful.

Talk to your doctor or pharmacist about whether this product is right for your situation.

Side effects, ingredient by ingredient 4-androsterone

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — 4-androsterone.
  • The most serious interaction on file is rated Moderate.
  • For scale: 8 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take testosterone replacement therapy or any testosterone product, do not start Andriol without checking first—Moderate interaction risk. Use the medication checker on this page to verify your prescriptions and any over-the-counter testosterone products before you begin.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Andriol is a prohormone product meant to boost testosterone levels, but safety data is sparse and hormone-disrupting effects are a real concern. If you take testosterone therapy, this product poses a documented Moderate interaction risk.

Anyone considering it should check with their pharmacist about their exact medications and talk with their doctor about whether the benefits outweigh the unknowns.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 25, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Andriol, straight from the product label.

Brand HTP Hi-Tech Pharmaceuticals
Net contents 60 Tablet(s)
Market status On market
Date entered into DSLD Mar 25, 2025
DSLD ID 321886
Product type Non-nutrient/non-botanical
Supplement form Tablet Or Pill
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Andriol by HTP Hi-Tech Pharmaceuticals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
1 Tablet(s)
Servings per container
60
IngredientAmount% DV
Androst-4-en-3beta-ol-17-one undecanoate158 mg--

Other ingredients: Microcrystalline Cellulose, Caprylic Acid, Caproic Acid, Capric Acid, Lauric Acid, Beta-Cyclodextrin, Phytosterols, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Testosterone replenishment testocaps SEDDS delivery Elevates androgen and testosterone levels

Seals/Symbols

Sourced from a GMP Certified Facility Good Manufacturing Practice Quality Assured

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Andriol by HTP Hi-Tech Pharmaceuticals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Andriol label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Andriol by HTP Hi-Tech Pharmaceuticals

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container60 Amounts shown are per serving.

Androst-4-en-3beta-ol-17-one undecanoate

Interacts with
8 drugs
158 mg per serving

4-Androsterone (sometimes called 4-DHEA) is a lab-made prohormone marketed to bodybuilders as a way to raise testosterone and build muscle, but human...

Androst-4-en-3beta-ol-17-one undecanoate monograph & interactions

Other (inactive) ingredients: Microcrystalline Cellulose, Caprylic Acid, Caproic Acid, Capric Acid, Lauric Acid, Beta-Cyclodextrin, Phytosterols, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Andriol by HTP Hi-Tech Pharmaceuticals Drug Interactions

Want to check YOUR meds against Andriol?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
8Drugs
8 Moderate

Ingredients driving the most interactions

Androst-4-en-3beta-ol-17-one undecanoate 8

Individual Drug Interactions

The ingredients in Andriol interact with 8 drugs. Click any drug to see the details.

1 of the 1 ingredient in Andriol interact with drugs. Each result below shows which ingredient is responsible. Androst-4-en-3beta-ol-17-one undecanoate

Each ingredient & the kinds of drugs it affects

For each ingredient in Andriol with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Androst-4-en-3beta-ol-17-one undecanoate1 drug type · 8 drugs

Testosterone

4-Androsterone is purportedly converted to testosterone and other androgens upon ingestion. Theoretically, taking 4-androsterone with testosterone may increase the risk for additive adverse effects such as mood disturbances and cardiovascular, kidney, or liver problems.

Likelihood Possible Evidence D
Androst-4-en-3beta-ol-17-one undecanoate full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Andriol, from the product label.

HTP Hi-Tech Pharmaceuticals

See all HTP Hi-Tech Pharmaceuticals products
Name
Hi-Tech Pharmaceuticals
Pharmacist Counseling Corner

Andriol by HTP Hi-Tech Pharmaceuticals: Common Questions

Does Andriol by HTP Hi-Tech Pharmaceuticals interact with any medications?
Yes. Based on its ingredients, Andriol has a known interaction with 8 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Andriol contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take Andriol while I'm pregnant?
No. Androgenic hormones can harm a developing baby, so you should not use Andriol during pregnancy. Talk to your doctor about safer options if you need support during that time.
Can I take Andriol while breastfeeding?
No. The hormonal effects on a nursing infant aren't known and could potentially be harmful, so it's best to avoid this product while you're breastfeeding.
What are the possible side effects of 4-androsterone?
Detailed adverse effect data for 4-androsterone is limited, but since it may be converted to testosterone-like compounds in your body, there's theoretical concern for serious effects including stroke, kidney failure, and liver injury—similar to anabolic steroids. Prohormones can also disrupt hormones, strain the liver, and affect cholesterol.
What is 4-androsterone and how is it supposed to work?
4-androsterone is a prohormone, meaning your body may convert it into testosterone and related male hormones. It's marketed to help boost testosterone levels, though evidence for effectiveness isn't established in our data.
Is Andriol safe for long-term use?
Safety for long-term use isn't well studied. Prohormones can disrupt hormones, strain the liver, and affect cholesterol, so talk to your doctor before starting and keep using it under medical supervision if at all.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Andriol label
Go deeper

The Full Monographs Behind Andriol’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

4-androsterone

Interacts with 8 drugs

4-Androsterone (sometimes called 4-DHEA) is a lab-made prohormone marketed to bodybuilders as a way to raise testosterone and build muscle, but human studies are very limited and it carries...

Read the full 4-androsterone monograph →
Sources

Sources & How We Checked

Andriol's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

4-androsterone 3 references
  1. Anabolic Steroids and Other Appearance and Performance Enhancing Drugs (APEDs) — NIH National Institute on Drug Abuse Source
  2. Dietary Supplements for Exercise and Athletic Performance — NIH Office of Dietary Supplements Source
  3. DHEA — MedlinePlus Source

See these in context on the 4-androsterone monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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