Halodrol Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Halodrol against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Halodrol is a dietary supplement by Gaspari Nutrition with 5 active ingredients. Its ingredients are commonly taken for muscle building and athletic performance, boosting testosterone or androgen levels, supporting libido.Based on those ingredients, 776 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Androstenolone Acetate, Rhaponticum carthamoides 100:1 extract, Androsterone. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Halodrol by Gaspari Nutrition
Ask about any prescription or over-the-counter medication and we check it for interactions with Halodrol by Gaspari Nutrition — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Halodrol by Gaspari Nutrition
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Halodrol contains 5 active ingredients, all of them androgenic or hormonal compounds. Androsterone is an androgenic hormone; 1-androstene-3b-ol, 17-one and 4-androstene-3b-ol, 17-one are prohormones that the body converts to testosterone-like compounds; androstenolone acetate (DHEA) is a naturally occurring hormone precursor that supports a range of functions; and rhaponticum carthamoides extract (maral root) is an adaptogenic plant compound.
The product also contains inactive ingredients including microcrystalline cellulose, phosphatidylcholine, hydroxypropyl beta cyclodextrin, phytosterols, magnesium stearate, silica, and colorants.
Does it work?
Leans against
The evidence we hold is limited. Androstenolone acetate (DHEA) is rated Likely Effective for vaginal atrophy and Possibly Effective for infertility, depression, and aging skin.
Androsterone, 1-androstene-3b-ol, 17-one, 4-androstene-3b-ol, 17-one, and rhaponticum carthamoides all lack sufficient reliable evidence to rate their effectiveness for any claimed use.
How safe is it?
Well-documented data
This product raises serious safety concerns. Androsterone is a controlled anabolic steroid illegal to sell as a dietary supplement in the U.S., and it is possibly unsafe—there is real concern it may cause heart disease and liver injury.
The other prohormones (1-androstene-3b-ol, 17-one and 4-androstene-3b-ol, 17-one) have limited safety testing and may cause anabolic steroid-like effects including stroke, kidney failure, and liver damage. Common adverse effects from the hormonal ingredients include acne, headache, insomnia, mood changes, nausea, and in women, masculinization (voice deepening, irregular periods, increased hair growth).
DHEA-induced mania, anxiety, and depression have been reported. Studies show 1-androstene-3b-ol, 17-one can raise harmful LDL cholesterol and lower protective HDL cholesterol, and may impair kidney function.
None of these ingredients are safe in pregnancy or while breastfeeding—hormonal effects on a developing baby or nursing infant are serious.
Meds to double-check
Moderate interaction found
Before you take this product, check with your pharmacist if you are on testosterone or other androgens (Minor severity), antidepressants, blood thinners (anticoagulants or antiplatelets like aspirin or warfarin), any drug metabolized by the liver enzyme CYP3A4, cancer medications including aromatase inhibitors, tamoxifen, or fulvestrant, triazolam (Halcion), or if you have received a tuberculosis vaccine—all are documented Moderate interactions (Moderate).
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with graded evidence leaning against its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This is a prohormone product containing controlled and research-limited substances. It is not appropriate for most people, and especially not for anyone taking testosterone, antidepressants, blood thinners, or cancer medications.
If you are considering it, speak with your pharmacist or doctor first—the legal and safety issues are substantial.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 5 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 20, 2017.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Halodrol, straight from the product label.
| Brand | Gaspari Nutrition |
|---|---|
| Barcode (UPC) | 646511023529 |
| Net contents | 30 Tablet(s) |
| Market status | On market |
| Date entered into DSLD | Nov 20, 2017 |
| DSLD ID | 80236 |
| Product type | Other Combinations |
| Supplement form | Tablet Or Pill |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Halodrol by Gaspari Nutrition, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Androsterone | 0 NP | -- |
| Proprietary Anabolic Blend | 250 mg | -- |
| 1-Androstene-3b-ol, 17-one | 0 NP | -- |
| 4-Androstene-3b-ol, 17-one | 0 NP | -- |
| Androstenolone Acetate | 0 NP | -- |
| Rhaponticum carthamoides 100:1 extract | 0 NP | -- |
Other ingredients: Microcrystalline Cellulose, Phosphatidylcholine, Hydroxypropyl Beta Cyclodextrin, Phytosterols, Magnesium Stearate, Silica, FD&C Blue # 2, FD&C Yellow #5
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
Maximal muscle myotropic developer
Bodybuilding's most anabolically-potent, single-dose tablet! Amino Acid retention catalyst-enhances protein synthesis Natural anabolic and anti-proteolytic formulation
Boost Testosterone levels and enhance athletic performance
Made in the USA from domestic and international ingredients.
Gaspari Nutrition commissioned the brightest scientific minds to develop a worthy successor to this widely popular product. The goal was to develop an even more potent and effective formula that would be worthy of sporting the Halodrol namesake.
These compounds provide the body with intense myotropic growth via enhancement of key bodily processes shown to upregulate Androgen receptor activation, protein synthesis, and net nitrogen retention.
Precautions
Warning: Not for use by individuals under the age of 18.
Do not use if pregnant or nursing. Consult a physician or licensed qualified healthcare professional before using this product if you have, or have a family history of, breast cancer, prostate cancer, prostate enlargement, heart disease, low "good" cholesterol (HDL), or if you are using any other dietary supplement, prescription drug, or over-the-counter drug.
Do not exceed recommended serving. Exceeding recommended serving may cause serious adverse health effects.
Possible side effects include acne, hair loss, hair growth on the face (in women), aggressiveness, irritability, and increased levels of estrogen. Discontinue use and call a physician or licensed qualified healthcare professional immediately if you experience rapid heartbeat, dizziness, blurred vision, or other similar symptoms.
Keep out of reach of children.
Suggested/Recommended/Usage/Directions
Directions: As a dietary supplement, take one tablet 30 minutes prior to training. On non-training days take one tablet in the morning or afternoon. Do not exceed 2 per day.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
General
REV 0416
Brand IP Statement(s)
2016 Gaspari Nutrition –All rights reserved.
Halodrol is the latest evolution of the legendary Halodrol-50 made famous by Gaspari Nutrition over a decade ago.
Gaspari is proud to introduce the new Halodrol, a patented, cutting-edge legal anabolic agent that is undeniably the most scientifically advanced and potent product in its class.
Halodrol derives its powerful anabolic effects primarily from patented naturally occurring DHEA derivatives.
Halodrol provides these potent muscle building compounds at the precise levels shown to maximize size, strength, & output, giving you everything needed to take your gains to entirely new heights. To ensure Halodrol provides you with the results you demand, each tablet is infused with a dual-phase delivery system, systematically designed to allow the active components to bypass stomach & liver degradation, allowing for never-before-seen bioavailability and absorption.
This novel delivery system is what makes Halodrol capable of providing you with significantly higher blood hormone levels, resulting in unparalleled gains when compared to absolutely anything else available on the market.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Halodrol by Gaspari Nutrition label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Halodrol by Gaspari Nutrition
These are the 5 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Proprietary Anabolic Blend
Other (inactive) ingredients: Microcrystalline Cellulose, Phosphatidylcholine, Hydroxypropyl Beta Cyclodextrin, Phytosterols, Magnesium Stearate, Silica, FD&C Blue # 2, FD&C Yellow #5. These complete the product’s ingredient list but are not active constituents.
Halodrol by Gaspari Nutrition Drug Interactions
HelloPharmacist Interaction Report
Halodrol by Gaspari Nutrition contains several androgenic and hormonal compounds that interact with medications.
The most serious concern is androsterone, which may cause additive adverse effects (cardiovascular, kidney, and liver problems, plus mood changes) when combined with testosterone or other androgens.
Read the full breakdown — every affected drug type, severity by severity
The product's other active ingredients carry multiple Moderate-severity interactions. Androstenolone Acetate (DHEA) interacts with antidepressants—there's a documented case of mania when an SSRI was used alongside DHEA—as well as with blood thinners (anticoagulants and antiplatelets), drugs metabolized by the liver enzyme CYP3A4, certain cancer medications (aromatase inhibitors, tamoxifen, and fulvestrant), the sleep medication triazolam (Halcion), and the tuberculosis vaccine.
Both 1-androstene-3b-ol, 17-one and 4-androstene-3b-ol, 17-one are converted to testosterone-like compounds and may cause similar additive effects with testosterone itself. Rhaponticum carthamoides extract may increase bleeding risk with blood thinners.
Additionally, note that androsterone is a controlled anabolic steroid illegal to sell as a dietary supplement in the U.S., and the other hormonal ingredients have limited safety testing. Altogether, these interactions span 766 individual medications.
Please check your exact medications with the search tool on this page before starting.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Halodrol?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Halodrol interact with 776 drugs. Click any drug to see the details.
5 of the 5 ingredients in Halodrol interact with drugs. Each result below shows which ingredient is responsible. Androstenolone Acetate Rhaponticum carthamoides 100:1 extract Androsterone 1-Androstene-3b-ol, 17-one 4-Androstene-3b-ol, 17-one
Ado-trastuzumab EmtansineKadcyla
How Ado-trastuzumab Emtansine interacts with Halodrol — through 1 ingredient. Tap an ingredient for the detail:
Androstenolone AcetateCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, DHEA might increase the levels of drugs metabolized by CYP3A4.
Read the full Androstenolone Acetate + Ado-trastuzumab Emtansine interactionAbciximabReoPro
How Abciximab interacts with Halodrol — through 2 ingredients. Tap an ingredient for the detail:
Rhaponticum Carthamoides 100:1 ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
In vitro research shows that maral root tincture can reduce platelet aggregation.
Read the full Rhaponticum Carthamoides 100:1 Extract + Abciximab interactionAndrostenolone AcetateAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, DHEA might increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Androstenolone Acetate + Abciximab interactionAbemaciclibVerzenio
How Abemaciclib interacts with Halodrol — through 1 ingredient. Tap an ingredient for the detail:
Androstenolone AcetateCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, DHEA might increase the levels of drugs metabolized by CYP3A4.
Read the full Androstenolone Acetate + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Halodrol — through 1 ingredient. Tap an ingredient for the detail:
Androstenolone AcetateCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, DHEA might increase the levels of drugs metabolized by CYP3A4.
Read the full Androstenolone Acetate + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Halodrol — through 1 ingredient. Tap an ingredient for the detail:
Androstenolone AcetateCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, DHEA might increase the levels of drugs metabolized by CYP3A4.
Read the full Androstenolone Acetate + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Halodrol — through 2 ingredients. Tap an ingredient for the detail:
Androstenolone AcetateAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, DHEA might increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Androstenolone Acetate + Abrocitinib interactionRhaponticum Carthamoides 100:1 ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
In vitro research shows that maral root tincture can reduce platelet aggregation.
Read the full Rhaponticum Carthamoides 100:1 Extract + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Halodrol — through 1 ingredient. Tap an ingredient for the detail:
Androstenolone AcetateCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, DHEA might increase the levels of drugs metabolized by CYP3A4.
Read the full Androstenolone Acetate + Acalabrutinib interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Halodrol — through 2 ingredients. Tap an ingredient for the detail:
Rhaponticum Carthamoides 100:1 ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
In vitro research shows that maral root tincture can reduce platelet aggregation.
Read the full Rhaponticum Carthamoides 100:1 Extract + Acenocoumarol interactionAndrostenolone AcetateAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, DHEA might increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Androstenolone Acetate + Acenocoumarol interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Halodrol — through 2 ingredients. Tap an ingredient for the detail:
Androstenolone AcetateAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, DHEA might increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Androstenolone Acetate + Acetaminophen, Aspirin interactionRhaponticum Carthamoides 100:1 ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
In vitro research shows that maral root tincture can reduce platelet aggregation.
Read the full Rhaponticum Carthamoides 100:1 Extract + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Halodrol — through 2 ingredients. Tap an ingredient for the detail:
Androstenolone AcetateAnticoagulant/antiplatelet Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, DHEA might increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Androstenolone Acetate + Acetaminophen, Aspirin, Caffeine interactionRhaponticum Carthamoides 100:1 ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
In vitro research shows that maral root tincture can reduce platelet aggregation.
Read the full Rhaponticum Carthamoides 100:1 Extract + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Halodrol — through 1 ingredient. Tap an ingredient for the detail:
Androstenolone AcetateCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, DHEA might increase the levels of drugs metabolized by CYP3A4.
Read the full Androstenolone Acetate + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Halodrol — through 1 ingredient. Tap an ingredient for the detail:
Androstenolone AcetateCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, DHEA might increase the levels of drugs metabolized by CYP3A4.
Read the full Androstenolone Acetate + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Halodrol — through 1 ingredient. Tap an ingredient for the detail:
Androstenolone AcetateCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, DHEA might increase the levels of drugs metabolized by CYP3A4.
Read the full Androstenolone Acetate + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Halodrol — through 1 ingredient. Tap an ingredient for the detail:
Androstenolone AcetateCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, DHEA might increase the levels of drugs metabolized by CYP3A4.
Read the full Androstenolone Acetate + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Halodrol — through 1 ingredient. Tap an ingredient for the detail:
Androstenolone AcetateCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, DHEA might increase the levels of drugs metabolized by CYP3A4.
Read the full Androstenolone Acetate + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Halodrol — through 1 ingredient. Tap an ingredient for the detail:
Androstenolone AcetateCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, DHEA might increase the levels of drugs metabolized by CYP3A4.
Read the full Androstenolone Acetate + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Halodrol — through 1 ingredient. Tap an ingredient for the detail:
Androstenolone AcetateCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, DHEA might increase the levels of drugs metabolized by CYP3A4.
Read the full Androstenolone Acetate + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Halodrol — through 1 ingredient. Tap an ingredient for the detail:
Androstenolone AcetateCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, DHEA might increase the levels of drugs metabolized by CYP3A4.
Read the full Androstenolone Acetate + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Halodrol — through 1 ingredient. Tap an ingredient for the detail:
Androstenolone AcetateCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, DHEA might increase the levels of drugs metabolized by CYP3A4.
Read the full Androstenolone Acetate + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Halodrol — through 1 ingredient. Tap an ingredient for the detail:
Androstenolone AcetateCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, DHEA might increase the levels of drugs metabolized by CYP3A4.
Read the full Androstenolone Acetate + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Halodrol — through 1 ingredient. Tap an ingredient for the detail:
Androstenolone AcetateCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, DHEA might increase the levels of drugs metabolized by CYP3A4.
Read the full Androstenolone Acetate + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Halodrol — through 1 ingredient. Tap an ingredient for the detail:
Androstenolone AcetateCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, DHEA might increase the levels of drugs metabolized by CYP3A4.
Read the full Androstenolone Acetate + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Halodrol — through 1 ingredient. Tap an ingredient for the detail:
Androstenolone AcetateCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, DHEA might increase the levels of drugs metabolized by CYP3A4.
Read the full Androstenolone Acetate + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with Halodrol — through 1 ingredient. Tap an ingredient for the detail:
Androstenolone AcetateCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, DHEA might increase the levels of drugs metabolized by CYP3A4.
Read the full Androstenolone Acetate + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, SalicylamideRhinogesic GG
How Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interacts with Halodrol — through 1 ingredient. Tap an ingredient for the detail:
Androstenolone AcetateCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, DHEA might increase the levels of drugs metabolized by CYP3A4.
Read the full Androstenolone Acetate + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylephrineAlka-Seltzer PLUS, Histex SR, Protid
How Acetaminophen, Chlorpheniramine, Phenylephrine interacts with Halodrol — through 1 ingredient. Tap an ingredient for the detail:
Androstenolone AcetateCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, DHEA might increase the levels of drugs metabolized by CYP3A4.
Read the full Androstenolone Acetate + Acetaminophen, Chlorpheniramine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, Phenylephrine, SalicylamideRhinogesic, Rhinogesic JR
How Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interacts with Halodrol — through 1 ingredient. Tap an ingredient for the detail:
Androstenolone AcetateCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, DHEA might increase the levels of drugs metabolized by CYP3A4.
Read the full Androstenolone Acetate + Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylpropanolamineAlumadrine, Conex, Sinadrin Max Strength, Sinulin
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine interacts with Halodrol — through 1 ingredient. Tap an ingredient for the detail:
Androstenolone AcetateCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, DHEA might increase the levels of drugs metabolized by CYP3A4.
Read the full Androstenolone Acetate + Acetaminophen, Chlorpheniramine, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, OpiumHista-Derfule
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interacts with Halodrol — through 1 ingredient. Tap an ingredient for the detail:
Androstenolone AcetateCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, DHEA might increase the levels of drugs metabolized by CYP3A4.
Read the full Androstenolone Acetate + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, PhenyltoloxamineNorel Plus
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interacts with Halodrol — through 1 ingredient. Tap an ingredient for the detail:
Androstenolone AcetateCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, DHEA might increase the levels of drugs metabolized by CYP3A4.
Read the full Androstenolone Acetate + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Halodrol with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Androstenolone Acetate
Anticoagulant/Antiplatelet Drugs
Theoretically, DHEA might increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Human and laboratory research show that DHEA and DHEA-S can inhibit platelet aggregation.
Antidepressant Drugs
Theoretically, DHEA might increase the risk of psychiatric adverse events when used with antidepressants.
In a human case report, the use of a selective serotonin reuptake inhibitor (SSRI) with DHEA caused a manic episode. Concern for this interaction may be greater in younger individuals with higher baseline DHEA levels.
Aromatase Inhibitors
Theoretically, DHEA might interfere with the clinical effects of aromatase inhibitors.
DHEA is a potent estrogen agonist, which may antagonize the anti-estrogen activity of aromatase inhibitors.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, DHEA might increase the levels of drugs metabolized by CYP3A4.
Some preliminary evidence shows that DHEA may inhibit CYP3A4; however, the clinical significance of this potential interaction is not known.
Fulvestrant (Faslodex)
Theoretically, DHEA might interfere with the anti-estrogen effects of fulvestrant.
DHEA is a potent estrogen agonist. Some research shows that it can overcome the estrogen receptor antagonist action of fulvestrant in estrogen-receptor positive cancer cells.
Tamoxifen (Nolvadex)
Theoretically, DHEA might interfere with the anti-estrogen effects of tamoxifen.
DHEA is a potent estrogen agonist. Some research shows that it can overcome the estrogen receptor antagonist activity of tamoxifen in estrogen-receptor positive cancer cells.
Triazolam (Halcion)
DHEA can increase blood levels of triazolam.
Administration of DHEA 200 mg daily for two weeks was shown to inhibit the cytochrome P450 3A4 (CYP3A4) metabolism of triazolam. This inhibition appears to be due to DHEA-S, rather than DHEA.
Tuberculosis Vaccine
DHEA might reduce the effectiveness of the tuberculosis vaccine.
Animal research shows that high doses of DHEA can reduce the efficacy of the Bacillus Calmette-Guérin (BCG) tuberculosis vaccine.
Estrogens
Theoretically, DHEA might increase the effects and adverse effects of estrogen therapy.
DHEA is a precursor to estrogen and androgen and is metabolized into those substances. In clinical research, DHEA supplements increase the levels of these hormones. Also, in clinical research, estrogen-progestin oral contraceptives and conjugated estrogens reduce blood levels of DHEA and DHEA-S. The clinical significance of these findings is unclear.
Testosterone
Theoretically, DHEA might increase the effects and side effects of testosterone therapy.
DHEA is a precursor to estrogen and androgen and is metabolized into those substances. In clinical research, DHEA supplements increase the levels of these hormones. The clinical significance of these findings is unclear.
Rhaponticum carthamoides 100:1 extract
Anticoagulant/Antiplatelet Drugs
In vitro research shows that maral root tincture can reduce platelet aggregation. Theoretically, maral root might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs. Some of these drugs include aspirin, clopidogrel (Plavix), nonsteroidal anti-inflammatory drugs (NSAIDs) such as diclofenac (Voltaren, Cataflam, others), ibuprofen (Advil, Motrin, others), naproxen (Anaprox, Naprosyn, others), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, warfarin (Coumadin), and others.
Androsterone
Androgens
Androsterone, as an androgenic hormone, may interact with other androgenic drugs, such as testosterone, due to their similar mechanisms of action. Both androsterone and testosterone bind to androgen receptors in various tissues throughout the body, leading to similar physiological effects related to the development and maintenance of male secondary sexual characteristics. When taken together, these compounds can potentially amplify these effects, leading to an increased risk of androgenic side effects, such as acne, hair loss, and changes in libido. Additionally, combining androsterone with testosterone or other androgenic drugs may also affect hormone levels and balance in the body, potentially leading to hormonal imbalances or disruptions in the endocrine system.
1-Androstene-3b-ol, 17-one
Testosterone
Theoretically, taking 1-androsterone with testosterone might increase the risk for additive adverse effects such as mood disturbances and cardiovascular, kidney, or liver problems.
1-Androsterone is converted to 1-testosterone and other androgens upon ingestion.
4-Androstene-3b-ol, 17-one
Testosterone
4-Androsterone is purportedly converted to testosterone and other androgens upon ingestion. Theoretically, taking 4-androsterone with testosterone may increase the risk for additive adverse effects such as mood disturbances and cardiovascular, kidney, or liver problems.
Brand information
Manufacturer and brand details for Halodrol, from the product label.
Gaspari Nutrition
See all Gaspari Nutrition products- Name
- Gaspari Nutrition
- Street Address
- 575 Prospect Street, Suite 301
- City
- Lakewood
- State
- NJ
- ZipCode
- 08701
- Phone Number
- 1-732-364-3777
- Web Address
- gasparinutrition.com
Halodrol by Gaspari Nutrition: Common Questions
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Halodrol is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Halodrol’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Androsterone
Interacts with 9 drugsAndrosterone is a natural androgenic steroid hormone made in the body, but supplement versions are classified as anabolic-androgenic steroids and are banned from U.S. dietary supplements und...
Read the full Androsterone monograph → Herb & supplement monograph1-androsterone
Interacts with 8 drugs1-Androsterone (1-DHEA or 1-Andro) is a synthetic prohormone marketed to bodybuilders for muscle and strength gains, but it has not been proven safe or effective in quality human studies. It...
Read the full 1-androsterone monograph → Herb & supplement monograph4-androsterone
Interacts with 8 drugs4-Androsterone (sometimes called 4-DHEA) is a lab-made prohormone marketed to bodybuilders as a way to raise testosterone and build muscle, but human studies are very limited and it carries...
Read the full 4-androsterone monograph → Herb & supplement monographDhea
Interacts with 776 drugsDHEA is a natural hormone that the body makes and that declines with age, and it is sold as a supplement claiming many benefits. The evidence is mixed and limited for most uses, and because...
Read the full Dhea monograph → Herb & supplement monographMaral Root
Interacts with 122 drugsMaral Root (Rhaponticum carthamoides) is a Siberian herb used as an 'adaptogen' and is popular among athletes for stamina and muscle building, largely because it contains plant compounds cal...
Read the full Maral Root monograph →Sources & How We Checked
Halodrol's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 106 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Androsterone 1 reference
- Joseph JF, Parr MK. Synthetic androgens as designer supplements. Curr Neuropharmacol. 2015;13(1):89-100. PubMed
1-androsterone 2 references
- Parr MK, Opfermann G, Geyer H, et al. Seized designer supplement named "1-Androsterone": identification as 3ß-hydroxy-5a-androst-1-en-17-one and its urinary elimination. Steroids 2011;76(6):540-7.
- Granados J, Gillum TL, Christmas KM, et al. Prohormone supplement 3b-hydroxy-5a-androst-1-en-17-one enhances resistance training gains but impairs user health. J Appl Physiol (1985). 2014;116(5):560-9.
4-androsterone 3 references
Dhea 98 references
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