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Dietary supplement

Extra Strength Astragalus 3,000 mg Ingredients & Drug Interactions

by Nature's Truth

Extra Strength Astragalus 3,000 mg label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Extra Strength Astragalus 3,000 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Extra Strength Astragalus 3,000 mg is a dietary supplement by Nature's Truth with 1 active ingredient. Its ingredients are commonly taken for immune support, colds and flu, upper respiratory infections.Based on those ingredients, 208 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Astragalus. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Extra Strength Astragalus 3,000 mg by Nature's Truth

Ask about any prescription or over-the-counter medication and we check it for interactions with Extra Strength Astragalus 3,000 mg by Nature's Truth — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Extra Strength Astragalus 3,000 mg by Nature's Truth

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • “Astragalus” is listed as a grouped ingredient — the label gives one combined amount (3,000 mg) without saying how much of each component you get.

This product is made from astragalus root extract — a traditional herb that's been used for centuries. There's one active ingredient, and it comes in capsule form with a few inactive ingredients (rice powder, gelatin, magnesium stearate, and silica) that help hold the capsule together and keep the powder flowing smoothly.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Astragalus's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: Traditional herbal immune support.
  • We looked for evidence on: Upper respiratory tract infection (URTI), Chronic fatigue syndrome (CFS), Chemotherapy-related fatigue, Post-stroke fatigue, Heart failure, HIV/AIDS — and 3 related terms.
  • The closest evidence on file: Astragalus is rated "Insufficient Reliable Evidence To Rate" for Chemotherapy-related fatigue (Natural Medicines).
  • Also on file: Astragalus is rated "Insufficient Reliable Evidence To Rate" for Chronic fatigue syndrome (CFS), Upper respiratory tract infection (URTI), Heart failure, HIV/AIDS, and more.

The evidence for astragalus falls short right now. The data we hold shows insufficient reliable evidence to rate it for allergic rhinitis (hay fever), amenorrhea, aplastic anemia, angina, asthma, and beta-thalassemia.

That means the research backing its use for these conditions isn't established enough yet to say whether it works.

The evidence, ingredient by ingredient Astragalus

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Astragalus is generally well tolerated in the short term for healthy adults, but human safety data is limited overall. One trial reported a case of angina and another mentioned dizziness, though it's unclear whether astragalus caused them.

Oral dosing has also been linked to dizziness in a small number of people, and IV administration has been associated with temporary palpitations, rash, eczema, and itching. Pregnancy and breastfeeding are off the table — there isn't enough reliable safety data to know whether it's safe during either, so the evidence advises against it.

Talk with your doctor or pharmacist before using this product if you're pregnant, planning to become pregnant, or breastfeeding.

Side effects, ingredient by ingredient Astragalus

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Astragalus.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: immunosuppressants / transplant drugs; diabetes medications; lithium.
  • For scale: 208 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this product, double-check any immunosuppressants you're on (moderate severity), as well as lithium, cyclophosphamide, and antidiabetes medications — all moderate concerns. If you take any of these, run them through the checker on this page or ask your pharmacist.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Astragalus is generally well tolerated short-term, but it does interact with several medication types — especially immunosuppressants, lithium, and diabetes drugs. If you take any prescription medications, especially those three categories, check them against the interaction tool on this page before you start.

A quick conversation with your pharmacist can make sure this product won't interfere with what you're already taking.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 25, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Extra Strength Astragalus 3,000 mg, straight from the product label.

Brand Nature's Truth
Barcode (UPC) 840093113887
Net contents 90 Quick Release Capsule(s)
Market status On market
Date entered into DSLD Jul 25, 2024
DSLD ID 306686
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Extra Strength Astragalus 3,000 mg by Nature's Truth, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Quick Release Capsule(s)
Maximum serving Sizes:
2 Quick Release Capsule(s)
Servings per container
45
UPC/BARCODE
840093113887
IngredientAmount% DV
Astragalus root extract300 mg--
Astragalus3000 mg--

Other ingredients: Rice, Powder, Gelatin, Magnesium Stearate, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Seals/Symbols

100% Quality Satisfaction Guarantee

Our Non-GMO Pledge Visit Our Website

Formula

Extra Strength Astragalus 3,000 mg per serving Equivalent from 300 mg of 10:1 Extract per serving

Formulation

Gluten free Non GMO

Traditional herbal support

No gluten, wheat, yeast, milk, lactose, soy, artificial color, artificial flavor, artificial sweetener, preservatives. Non-GMO

FDA Statement of Identity

Herbal Supplement

Suggested/Recommended/Usage/Directions

Directions: For adults, take two (2) quick release capsules daily, preferably with a meal.

Precautions

Warning: If you are pregnant, nursing, taking any medications or have any medical condition, consult your doctor before use.

If any adverse reactions occur, immediately stop using this product and consult your doctor.

Not intended for use by persons under the age of 18. Keep out of reach of children.

If seal under cap is damaged or missing, do not use.

Storage

Store in a cool, dry place.

Brand IP Statement(s)

Copyright 2021 Nature's Truth LLC

General Statements

Vitamins

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Extra Strength Astragalus 3,000 mg by Nature's Truth label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Extra Strength Astragalus 3,000 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Extra Strength Astragalus 3,000 mg by Nature's Truth

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Quick Release Capsule(s) Dosage formCapsule Servings per container45 Amounts shown are per serving.

Astragalus

Interacts with
208 drugs
3000 mg per serving

Astragalus is a root used for centuries in traditional Chinese medicine, mainly to support the immune system and help the body cope with stress. While...

Astragalus monograph & interactions

Other (inactive) ingredients: Rice, Powder, Gelatin, Magnesium Stearate, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Extra Strength Astragalus 3,000 mg by Nature's Truth Drug Interactions

Want to check YOUR meds against Extra Strength Astragalus 3,000 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
208Drugs
208 Moderate

Ingredients driving the most interactions

Astragalus 208

Individual Drug Interactions

The ingredients in Extra Strength Astragalus 3,000 mg interact with 208 drugs. Click any drug to see the details.

1 of the 1 ingredient in Extra Strength Astragalus 3,000 mg interact with drugs. Each result below shows which ingredient is responsible. Astragalus

Each ingredient & the kinds of drugs it affects

For each ingredient in Extra Strength Astragalus 3,000 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Astragalus4 drug types · 208 drugs

Antidiabetes Drugs

Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research in humans shows that astragalus might have hypoglycemic effects. Theoretically, taking astragalus, especially in combination with other hypoglycemic agents, might increase the risk of hypoglycemia.

Likelihood Probable Evidence A
Cyclophosphamide

Theoretically, astragalus might interfere with cyclophosphamide therapy.
Evidence regarding the effect of astragalus on immunosuppression caused by cyclophosphamide is conflicting. Some animal research suggests that astragalus reverses cyclophosphamide-induced immunosuppression. However, other animal research shows no effect.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, astragalus might interfere with immunosuppressive therapy.
Astragalus seems to stimulate immune function. Theoretically, taking astragalus might decrease the effects of immunosuppressive therapy.

Likelihood Possible Evidence D
Lithium

Theoretically, astragalus might increase levels and adverse effects of lithium.
Animal research suggests that astragalus has diuretic properties. Theoretically, due to this diuretic effect, astragalus might reduce excretion and increase levels of lithium.

Likelihood Probable Evidence D
Astragalus full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Extra Strength Astragalus 3,000 mg, from the product label.

Nature's Truth

See all Nature's Truth products
Name
Nature's Truth LLC
City
Ronkonkoma
State
NY
ZipCode
11779
Phone Number
1-844-544-1030
Web Address
naturestruthproducts.com
Pharmacist Counseling Corner

Extra Strength Astragalus 3,000 mg by Nature's Truth: Common Questions

Does Extra Strength Astragalus 3,000 mg by Nature's Truth interact with any medications?
Yes. Based on its ingredients, Extra Strength Astragalus 3,000 mg has a known interaction with 208 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Extra Strength Astragalus 3,000 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
No — there isn't enough reliable safety data to know either way. The evidence advises against using it during pregnancy and while breastfeeding. Talk with your doctor or pharmacist about whether astragalus is right for you in these situations.
What exactly is astragalus root extract?
It's an extract from the root of the astragalus plant, a traditional herb. This product contains 3,000 mg of it per capsule.
Does this actually work for anything?
The research we have shows insufficient evidence to say whether it works for conditions like hay fever, asthma, angina, or the others listed. That doesn't mean it doesn't work — just that we don't have enough solid research backing it yet.
What side effects might I notice?
Most people tolerate it well short-term, but a small number in studies reported dizziness. Very rarely, rapid IV infusions have caused temporary heart palpitations, though this product is taken by mouth. Rash, eczema, and itching have been reported with IV dosing, not oral.
Is this product safe for long-term use?
The safety data we have focuses on short-term use in healthy adults — so we don't know much about safety over months or years. If you're thinking about taking it regularly, talk with your pharmacist first.
What are the inactive ingredients?
The capsule contains rice powder, gelatin, magnesium stearate, and silica — these are just fillers and binders to keep the capsule intact and the powder stable.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Extra Strength Astragalus 3,000 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Extra Strength Astragalus 3,000 mg label
Go deeper

The Full Monographs Behind Extra Strength Astragalus 3,000 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Astragalus

Interacts with 208 drugs

Astragalus is a root used for centuries in traditional Chinese medicine, mainly to support the immune system and help the body cope with stress. While early studies are interesting, strong h...

Read the full Astragalus monograph →
Sources

Sources & How We Checked

Extra Strength Astragalus 3,000 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 13 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Astragalus 13 references
  1. Upton R, ed. Astragalus Root: Analytical, quality control, and therapeutic monograph. Santa Cruz, CA: American Herbal Pharmacopoeia. 1999:1-25.
  2. Khoo KS, Ang PT. Extract of astragalus membranaceus and ligustrum lucidum does not prevent cyclophosphamide-induced myelosuppression. Singapore Med J 1995;36:387-90.
  3. Chu DT, Wong WL, Mavligit GM. Immunotherapy with Chinese medicinal herbs. II. Reversal of cyclophosphamide-induced immune suppression by administration of fractionated Astragalus membranaceus in vivo. J Clin Lab Immunol 1988;25:125-9.
  4. Sun Y, Hersh EM, Lee SL, et al. Preliminary observations on the effects of the Chinese medicinal herbs Astragalus membranaceus and Ligustrum lucidum on lymphocyte blastogenic responses. J Biol Response Mod 1983;2:227-37..
  5. Ma J, Peng A, Lin S. Mechanisms of the therapeutic effect of astragalus membranaceus on sodium and water retention in experimental heart failure. Chin Med J (Engl) 1998;111:17-23.
  6. Matkovic Z, Zivkovic V, Korica M, et al. Efficacy and safety of Astragalus membranaceus in the treatment of patients with seasonal allergic rhinitis. Phytother Res 2010;24:175-81.
  7. Zhang, J. G., Yang, N., He, H., Wei, G. H., Gao, D. S., Wang, X. L., Wang, X. Z., and Song, G. Y. [Effect of Astragalus injection on plasma levels of apoptosis-related factors in aged patients with chronic heart failure.]. Chin J Integr.Med 2005;11(3):18 PubMed
  8. Chen, H. W., Lin, I. H., Chen, Y. J., Chang, K. H., Wu, M. H., Su, W. H., Huang, G. C., and Lai, Y. L. A novel infusible botanically-derived drug, PG2, for cancer-related fatigue: a phase II double-blind, randomized placebo-controlled study. Clin Invest PubMed
  9. Tian H, Lu J, He H, et al.The effect of Astragalus as an adjuvant treatment in type 2 diabetes mellitus: A (preliminary) meta-analysis. J Ethnopharmacol. 2016;191:206-215. doi: 10.1016/j.jep.2016.05.062. PubMed
  10. Hong KF, Liu PY, Zhang W, Gui DK, Xu YH. The Efficacy and Safety of Astragalus as an Adjuvant Treatment for Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis. J Integr Complement Med 2023. PubMed
  11. Chan KW, Kwong ASK, Tsui PN, et al. Add-on astragalus in type 2 diabetes and chronic kidney disease: A multi-center, assessor-blind, randomized controlled trial. Phytomedicine 2024;130:155457. PubMed
  12. Han X, Yu T, Chen X, Du Z, Yu M, Xiong J. Effect of Astragalus membranaceus on left ventricular remodeling in HFrEF: a systematic review and meta-analysis. Front Pharmacol 2024;15:1345797. PubMed
  13. Jing P, Hongzheng H, Zhenqi WU, Meijuan Z, Zuojing LI, Gang C. Long-term efficacy and safety of Huangqi ()-based Traditional Chinese Medicine in diabetic peripheral neuropathy: a Meta-analysis of randomized controlled trials. J Tradit Chin Med 2024;44(2):

See these in context on the Astragalus monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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