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Dietary supplement

Fadogia Agrestis with Tongkat Ali Ingredients & Drug Interactions

by Dorado Nutrition

Fadogia Agrestis with Tongkat Ali label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Oct 7, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Fadogia Agrestis with Tongkat Ali against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Fadogia Agrestis with Tongkat Ali is a dietary supplement by Dorado Nutrition with 2 active ingredients. Its ingredients are commonly taken for boosting testosterone, improving libido and sexual function, athletic performance and muscle building.Based on those ingredients, 249 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Tongkat Ali powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Fadogia Agrestis with Tongkat Ali by Dorado Nutrition

Ask about any prescription or over-the-counter medication and we check it for interactions with Fadogia Agrestis with Tongkat Ali by Dorado Nutrition — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Fadogia Agrestis with Tongkat Ali by Dorado Nutrition

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains two active ingredients: Fadogia agrestis powder and Tongkat Ali powder. Tongkat Ali (also called Eurycoma longifolia) is a Southeast Asian plant traditionally used to support sexual function and athletic performance.

Fadogia agrestis is an African plant used in traditional medicine, though human safety and effectiveness data are very limited. The capsules also contain inactive ingredients — cellulose, magnesium stearate, and silicon dioxide — which are standard binders and fillers.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded its ingredients' overall clinical evidence instead.

Moderate

Some clinical evidence supports its ingredients for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredients' overall clinical evidence instead.
  • On file: Sexual desire — rated "Possibly Effective" (Eurycoma Longifolia) (Natural Medicines).

The evidence for what these ingredients actually do is thin. Tongkat Ali is rated possibly effective for sexual desire — some clinical studies back that claim.

For athletic performance, though, it's rated possibly ineffective, and evidence for back pain, osteoporosis, and diabetes is insufficient. Fadogia Agrestis has insufficient evidence for athletic performance, erectile dysfunction, and malaria — meaning we don't have reliable research showing whether it works for any of these uses.

If sexual function is your goal, Tongkat Ali has the strongest evidence, but for everything else here, the science just isn't solid yet.

The evidence, ingredient by ingredient Fadogia Agrestis Eurycoma Longifolia

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Tongkat Ali is generally well tolerated in short-term studies, but long-term safety is unclear, and product quality can vary. Fadogia Agrestis is a bigger concern: human safety data don't exist, and animal studies hint at possible damage to the testicles, liver, and kidneys — that's why caution is warranted.

Both ingredients should be avoided in pregnancy and while breastfeeding due to lack of safety data and possible hormonal effects. There's also a theoretical risk: if Tongkat Ali raises your testosterone beyond normal levels, you could develop acne, insulin resistance, liver stress, and other testosterone-related side effects.

Side effects, ingredient by ingredient Fadogia Agrestis Eurycoma Longifolia

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — Eurycoma Longifolia.
  • The most serious interaction on file is rated Moderate.
  • For scale: 249 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this product, double-check it against propranolol (Inderal) or any other beta-blocker — it's a moderate interaction that could weaken the drug's effect. Tongkat Ali may also theoretically raise levels of drugs broken down by your liver's CYP1A2, CYP2C19, and CYP2A6 systems; if you take any prescription metabolized by those pathways, verify it's safe.

And if you're on testosterone replacement or supplements, talk to your pharmacist about the risk of testosterone going too high.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

This product may interest men looking to support sexual function, where Tongkat Ali has some clinical backing. If you take propranolol or other blood pressure medications, or if you're on testosterone therapy, you need to check with your pharmacist before starting — the interactions are real.

Avoid this product if you're pregnant or breastfeeding. Because Fadogia Agrestis has minimal safety data and possible organ toxicity in animals, have a detailed conversation with your pharmacist about whether the benefit is worth the unknown risks.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Fadogia Agrestis with Tongkat Ali, straight from the product label.

Brand Dorado Nutrition
Barcode (UPC) X002QZ8HSZ
Net contents 120 Capsule(s)
Market status On market
Date entered into DSLD Aug 23, 2022
DSLD ID 272302
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Fadogia Agrestis with Tongkat Ali by Dorado Nutrition, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
60
UPC/BARCODE
X002QZ8HSZ
IngredientAmount% DV
Fadogia agrestis powder600 mg--
Tongkat Ali powder400 mg--

Other ingredients: Cellulose, Magnesium Stearate, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

Keep out of the reach of children.

Do not use if safety seal is damaged or missing.

Adult use only.

Caution: Do not exceed recommended dose.

This product is not intended for pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

This product is not intended for pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

Storage

Store in a cool, dry place.

Suggested/Recommended/Usage/Directions

Suggested Use: Take two (1) capsules a day. Take an additional serving 30 minutes prior to activity, if desired, or as directed by your healthcare provider.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

Made in the USA with global ingredients GMP Good Manufacturing Practice Product Third Party Certified

Formulation

Made with Non GMO Ingredients

Maximum Strength

General Statements

Made with Love

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Fadogia Agrestis with Tongkat Ali by Dorado Nutrition label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Fadogia Agrestis with Tongkat Ali label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Fadogia Agrestis with Tongkat Ali by Dorado Nutrition

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Fadogia agrestis powder

No known
interactions
600 mg per serving

Fadogia agrestis is a West African shrub marketed as a testosterone booster, but human evidence is essentially nonexistent and what we know comes most...

Fadogia agrestis powder monograph & interactions

Tongkat Ali powder

Interacts with
249 drugs
400 mg per serving

Eurycoma longifolia (tongkat ali) is a Southeast Asian herb most popular for supporting testosterone, libido, and male fertility, with some small huma...

Tongkat Ali powder monograph & interactions

Other (inactive) ingredients: Cellulose, Magnesium Stearate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Fadogia Agrestis with Tongkat Ali by Dorado Nutrition Drug Interactions

Want to check YOUR meds against Fadogia Agrestis with Tongkat Ali?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
249Drugs
3 Moderate 246 Minor

Ingredients driving the most interactions

Tongkat Ali powder 249

Individual Drug Interactions

The ingredients in Fadogia Agrestis with Tongkat Ali interact with 249 drugs. Click any drug to see the details.

1 of the 2 ingredients in Fadogia Agrestis with Tongkat Ali interact with drugs. Each result below shows which ingredient is responsible. Tongkat Ali powder

Each ingredient & the kinds of drugs it affects

For each ingredient in Fadogia Agrestis with Tongkat Ali with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Tongkat Ali powder5 drug types · 249 drugs

Propranolol (Inderal)

Eurycoma longifolia can reduce the levels and clinical effects of propranolol.
A small clinical study in healthy persons shows that taking a single dose of a water-based Eurycoma longifolia extract 200 mg, in combination with a single dose of propranolol 80 mg, reduces the propranolol area under the curve (AUC) by 29%, reduces the peak concentration by 42%, and increases time to peak concentration by 86% when compared with control. Since the elimination half-life of propranolol did not change, it seems that Eurycoma longifolia alters the kinetics of propranolol by decreasing its absorption in the gut, and not by altering its metabolism. It is not known if separating administration will prevent this interaction.

Likelihood Probable Evidence A
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP1A2 enzymes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2A6 (Cyp2A6) Substrates

Theoretically, Eurycoma longifolia might increase levels of CYP2A6 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP2A6 enzymes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C19 (Cyp2C19) Substrates

Theoretically, Eurycoma longifolia might increase levels of CYP2C19 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP2C19 enzymes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Testosterone

Theoretically, Eurycoma longifolia may further increase levels of testosterone.
A clinical study in aging males with testosterone levels below 300 ng/dL shows that taking a specific water extract of Eurycoma longifolia roots (Physta; Biotropics Malaysia) 100-200 mg daily with breakfast for 12 weeks increases total testosterone levels by 8% to 11% when compared with placebo. It is unclear whether this increase would occur in individuals with normal testosterone levels.

Likelihood Possible Evidence D
Tongkat Ali powder full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Fadogia Agrestis with Tongkat Ali, from the product label.

Dorado Nutrition

See all Dorado Nutrition products
Name
Dorado Nutrition
Street Address
30 N Gould St Ste 3784
City
Sheridan
State
WY
ZipCode
82801
Phone Number
(307) 201-2862
Web Address
www.DoradoNutrition.com
Pharmacist Counseling Corner

Fadogia Agrestis with Tongkat Ali by Dorado Nutrition: Common Questions

Does Fadogia Agrestis with Tongkat Ali by Dorado Nutrition interact with any medications?
Yes. Based on its ingredients, Fadogia Agrestis with Tongkat Ali has a known interaction with 249 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Fadogia Agrestis with Tongkat Ali contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
No. Both ingredients lack safety data in pregnancy and have possible hormonal effects, so the safety data advises against use in both cases. Talk with your doctor or pharmacist before considering it at any point around pregnancy or while nursing.
Does this product actually improve sexual function?
Tongkat Ali is rated possibly effective for sexual desire and has some clinical studies backing that. Fadogia Agrestis, on the other hand, has insufficient evidence — we don't know if it works. So if that's what you're after, Tongkat Ali is the stronger candidate, but neither has airtight proof.
Is this safe to take long-term?
Tongkat Ali is generally tolerated short-term in studies, but long-term safety is uncertain, and product quality varies widely. Fadogia Agrestis is more concerning — there's almost no human safety data, and animal studies suggest possible toxicity to the testicles, liver, and kidneys. This isn't a supplement to take indefinitely without medical oversight.
What are the side effects I should watch for?
If Tongkat Ali raises your testosterone beyond normal, you might develop acne, insulin resistance, liver stress, and other testosterone-related effects. Fadogia Agrestis has no documented adverse effects in humans, but that's only because there's barely any human data at all — not proof it's harmless.
How many active ingredients are in this product?
There are two: Fadogia agrestis powder and Tongkat Ali powder. The rest are inactive ingredients like cellulose and magnesium stearate that help form the capsule.
Should I take this if I'm on blood pressure medication?
It depends on which one. If you take propranolol (Inderal), this product can reduce how well it works — a moderate interaction. For other blood pressure drugs, check with your pharmacist using the medication tool on this page before you start.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Fadogia Agrestis with Tongkat Ali is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Fadogia Agrestis with Tongkat Ali label
Go deeper

The Full Monographs Behind Fadogia Agrestis with Tongkat Ali’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Fadogia Agrestis

Fadogia agrestis is a West African shrub marketed as a testosterone booster, but human evidence is essentially nonexistent and what we know comes mostly from a few small rat studies. Animal...

Read the full Fadogia Agrestis monograph → Herb & supplement monograph

Eurycoma Longifolia

Interacts with 249 drugs

Eurycoma longifolia (tongkat ali) is a Southeast Asian herb most popular for supporting testosterone, libido, and male fertility, with some small human studies suggesting possible benefits....

Read the full Eurycoma Longifolia monograph →
Sources

Sources & How We Checked

Fadogia Agrestis with Tongkat Ali's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Fadogia Agrestis 2 references
  1. Dietary Supplements: What You Need to Know — NIH Office of Dietary Supplements Source
  2. Using Dietary Supplements Wisely — NIH NCCIH Source

See these in context on the Fadogia Agrestis monograph →

Eurycoma Longifolia 4 references
  1. Salman SA, Amrah S, Wahab MS, et al. Modification of propranolol's bioavailability by Eurycoma longifolia water-based extract. J Clin Pharm Ther 2010;35:691-6. PubMed
  2. Tambi MI, Imran MK, Henkel RR. Standardised water-soluble extract of Eurycoma longifolia, Tongkat ali, as testosterone booster for managing men with late-onset hypogonadism? Andrologia 2011 Jun 15. doi: 10.1111/j.1439-0272.2011.01168.x. [Epub ahead of pri PubMed
  3. Han YM, Kim IS, Rehman SU, Choe K, Yoo HH. In vitro evaluation of the effects of Eurycoma longifolia extract on CYP-mediated drug metabolism. Evid Based Complement Alternat Med 2015;2015:631329.
  4. Chinnappan SM, George A, Pandey P, Narke G, Choudhary YK. Effect of Eurycoma longifolia standardised aqueous root extract-Physta ® on testosterone levels and quality of life in ageing male subjects: a randomised, double-blind, placebo-controlled multicent

See these in context on the Eurycoma Longifolia monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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