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Dietary supplement

FDgard Caraway Oil and I-Manthol Ingredients & Drug Interactions

by FDgard

FDgard Caraway Oil and I-Manthol label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking FDgard Caraway Oil and I-Manthol against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

FDgard Caraway Oil and I-Manthol is a dietary supplement by FDgard with 2 active ingredients. Its ingredients are commonly taken for digestive upset and bloating, gas (flatulence), indigestion (dyspepsia).Based on those ingredients, 413 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Caraway (Carum carvi) seed Oil. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against FDgard Caraway Oil and I-Manthol by FDgard

Ask about any prescription or over-the-counter medication and we check it for interactions with FDgard Caraway Oil and I-Manthol by FDgard — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of FDgard Caraway Oil and I-Manthol by FDgard

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

FDgard contains 2 active ingredients. Caraway seed oil is included for digestive support, particularly for indigestion (dyspepsia), where research suggests it may be helpful.

L-Menthol is the second active ingredient; we hold no detailed data on its specific role in this formulation. The product also contains several inactive ingredients — gelatin capsule material, cellulose compounds, and colorants — that serve as binders and fillers but don't contribute to the therapeutic effect.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: manage occasional indigestion and gut symptoms.
  • We looked for evidence on: Dyspepsia, Flatulence, Irritable bowel syndrome (IBS), Bloating, Digestive upset, Gas — and 1 related terms.
  • The strongest evidence on file: Caraway is rated "Possibly Effective" for Dyspepsia (Natural Medicines).
  • Also on file: Caraway is rated "Insufficient Reliable Evidence To Rate" for Flatulence, Irritable bowel syndrome (IBS).

Caraway oil is rated possibly effective for indigestion (dyspepsia). For other uses listed — amenorrhea (absent periods), asthma, constipation, and flatulence — the evidence is insufficient to rate it.

We have no effectiveness data on file for L-Menthol in this product.

The evidence, ingredient by ingredient Caraway

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Caraway oil is generally well tolerated in food amounts, but concentrated oils and supplement doses are less studied. In trials combining caraway with peppermint oil, some people reported substernal burning, belching, nausea, and vomiting — though it's unclear whether caraway, peppermint, or the combination caused these.

One allergic reaction was reported in someone with a history of asthma who took the combination. For pregnancy, caraway is rated possibly unsafe at medicinal or oil doses; food amounts are likely fine but data are limited.

Breastfeeding safety with concentrated supplements isn't well studied; food amounts are likely okay. We hold no safety data on L-Menthol.

Side effects, ingredient by ingredient Caraway

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Caraway.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications; lithium.
  • For scale: 413 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking FDgard, double-check your medications if you take CNS depressants (sedatives, sleep aids, anxiety meds), antidiabetes drugs, water pills (diuretics), or lithium — all carry moderate interaction risks with caraway. Also mention older tuberculosis drugs (isoniazid, rifampin, pyrazinamide) if you take them, though the risk is minor.

We could not check L-Menthol for interactions.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

FDgard may help with indigestion, but it's important to check it against your medications first — particularly if you take blood sugar drugs, sedatives, water pills, or lithium. Talk to your pharmacist or doctor before starting, especially if you're pregnant, breastfeeding, or have asthma.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about FDgard Caraway Oil and I-Manthol, straight from the product label.

Brand FDgard
Barcode (UPC) 369266000361
Net contents 36 Capsule(s)
Market status On market
Date entered into DSLD Sep 25, 2023
DSLD ID 288648
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for FDgard Caraway Oil and I-Manthol by FDgard, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
18
UPC/BARCODE
369266000361
IngredientAmount% DV
Caraway (Carum carvi) seed Oil50 mg--
L-Menthol41.5 mg--

Other ingredients: Gelatin, Microcrystalline Cellulose, Methylcellulose, Hypromellose, Methacrylic Acid Copolymer, Triethyl Citrate, Sodium Croscarmellose, Polysorbate 80, Glyceryl Monostearate, Titanium Dioxide, Red 3, Blue 1

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Powered by nature...perfected by science

Illustrative depiction of FDgard delivery Vista Color

Among gastroenterologists who recommended an herbal product for meal-triggered indigestion. Lieberman 2021. Chey WD, Lacy BE, Cash BD, Epstein M, et al. Clin Transl Gastroenterol. 2019; 10(4). Individual results may vary. Questions/comments: Call us toll free 1-855-GUT-GARD (1-855-488-4273) or visit www.FDgard.com Share your story #1 gastroenterologist recommended brand New look!

Share your story

Formulation

Say yes to dinner again knowing that your gut is supported.

Patented Site-Specific Targeting (SST) Technology delivers FDgard where it is needed in the gut FDgard started working on meal-triggered indigestion in as little as 24 hours

Meal-triggered indigestion Helps manage a combination of occasional symptoms: Bloating Nausea Upset stomach Difficulty finishing a meal

Suggested/Recommended/Usage/Directions

Take FDgard daily to help manage your occasional indigestion.

Suggested usage Adults, take two capsules, two times a day or as directed by a healthcare provider. Take 30 to 60 minutes before a meal, with water. If the pre-meal dose is missed, FDgard can be taken with or after a meal.

Formula

Caraway oil and l-Menthol work together to help relax the digestive system and manage occasional symptoms in the gut.

Precautions

Warnings: Consult with your healthcare provider before use if you are pregnant, nursing, taking any medications or have any medical condition.

Do not exceed 6 capsules a day. Discontinue use and consult your healthcare provider if symptoms persist or worsen, or any adverse reaction occurs.

Keep out of reach of children.

Do not use if blister is torn or ripped or if there is any other evidence of tampering.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Brand IP Statement(s)

All trademarks are owned by Societe des Produits Nestle S.A., Vevey, Switzerland, or used with permission. Copyright 2021 Nestle. Patents www.nestlehealthscience.us/consumerpatents

FDgard The PreMeal Companion

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

FDgard Caraway Oil and I-Manthol by FDgard label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

FDgard Caraway Oil and I-Manthol label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in FDgard Caraway Oil and I-Manthol by FDgard

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container18 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Caraway (Carum carvi) seed Oil

Interacts with
413 drugs
50 mg per serving

Caraway is a common cooking spice that has long been used to ease gas, bloating, and indigestion. Some evidence suggests caraway oil—often combined wi...

Caraway (Carum carvi) seed Oil monograph & interactions

L-Menthol

41.5 mg per serving Form: Mentha arvensis

Other (inactive) ingredients: Gelatin, Microcrystalline Cellulose, Methylcellulose, Hypromellose, Methacrylic Acid Copolymer, Triethyl Citrate, Sodium Croscarmellose, Polysorbate 80, Glyceryl Monostearate, Titanium Dioxide, Red 3, Blue 1. These complete the product’s ingredient list but are not active constituents.

Interaction report

FDgard Caraway Oil and I-Manthol by FDgard Drug Interactions

Want to check YOUR meds against FDgard Caraway Oil and I-Manthol?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
413Drugs
408 Moderate 5 Minor

Ingredients driving the most interactions

Caraway (Carum carvi) seed Oil 413

Individual Drug Interactions

The ingredients in FDgard Caraway Oil and I-Manthol interact with 413 drugs. Click any drug to see the details.

1 of the 2 ingredients in FDgard Caraway Oil and I-Manthol interact with drugs. Each result below shows which ingredient is responsible. Caraway (Carum carvi) seed Oil

Each ingredient & the kinds of drugs it affects

For each ingredient in FDgard Caraway Oil and I-Manthol with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Caraway (Carum carvi) seed Oil7 drug types · 413 drugs

Antidiabetes Drugs

Theoretically, caraway might increase the risk of hypoglycemia when used with antidiabetes drugs.
Animal research suggests that caraway can reduce blood glucose levels. Monitor blood glucose levels closely. Medication dose adjustments may be necessary.

Likelihood Possible Evidence D
Cns Depressants

Theoretically, caraway might increase the effects and adverse effects of CNS depressants.
Animal research suggests that (S)-(+)-carvone, a major constituent of caraway seed extract, has sedative effects.

Likelihood Possible Evidence D
Diuretic Drugs

Theoretically, caraway might increase the risk of hypokalemia when used with diuretics that deplete potassium.
Animal research suggests that a single dose of caraway fruit extract can promote diuresis and increase the urinary excretion of sodium and potassium. However, sub-chronic use of caraway fruit extract does not seem to significantly increase potassium excretion, although urine output continues to be increased for up to 6 days.

Likelihood Possible Evidence D
Lithium

Theoretically, caraway might reduce excretion and increase levels of lithium due to diuretic effects.
Animal research suggests that caraway fruit extract has diuretic properties.

Likelihood Possible Evidence D
Isoniazid

Theoretically, caraway might increase the effects and adverse effects of isoniazid.
Animal research suggests that a specific fraction of caraway seed extract (CC-1a) can increase plasma levels of isoniazid when administered concomitantly. This interaction has not been reported in humans.

Likelihood Possible Evidence D
Pyrazinamide

Theoretically, caraway might increase the effects and adverse effects of pyrazinamide.
Animal research suggests that a specific fraction of caraway seed extract (CC-1a) can increase plasma levels of pyrazinamide when administered concomitantly. This interaction has not been reported in humans.

Likelihood Possible Evidence D
Rifampin (Rifadin)

Theoretically, caraway might increase the effects and adverse effects of rifampin.
Animal research suggests that a specific fraction of caraway seed extract (CC-1a) can increase plasma levels of rifampin when administered concomitantly. This interaction has not been reported in humans.

Likelihood Possible Evidence D
Caraway (Carum carvi) seed Oil full monograph & interactions
The maker

Brand information

Manufacturer and brand details for FDgard Caraway Oil and I-Manthol, from the product label.

FDgard

See all FDgard products
Name
Nestle HealthCare Nutrition, Inc.
City
Bridgewater
State
NJ
ZipCode
08807
Phone Number
1-855-488-4273
Web Address
www.FDgard.com
Pharmacist Counseling Corner

FDgard Caraway Oil and I-Manthol by FDgard: Common Questions

Does FDgard Caraway Oil and I-Manthol by FDgard interact with any medications?
Yes. Based on its ingredients, FDgard Caraway Oil and I-Manthol has a known interaction with 413 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
FDgard Caraway Oil and I-Manthol contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take FDgard if I'm pregnant?
Caraway is rated possibly unsafe at medicinal or oil doses during pregnancy, so you should avoid supplement amounts. Food amounts of caraway are likely fine, but data are limited. Talk with your doctor or pharmacist before starting — it's an individual decision based on your situation.
Is FDgard safe while breastfeeding?
We don't have solid safety data on concentrated caraway supplements during breastfeeding. Food amounts are likely fine, but the supplement form isn't well studied. Check with your pharmacist or doctor before taking it.
What is caraway oil supposed to do?
Caraway oil is included for indigestion (dyspepsia), where research suggests it may be helpful — it's rated possibly effective for that use. It's not proven for constipation, flatulence, asthma, or absent periods.
Did anyone have side effects in trials?
When caraway was combined with peppermint oil in studies, some people reported chest burning, belching, nausea, and vomiting — though it's unclear if caraway alone caused them. One allergic reaction occurred in someone with asthma taking the combination.
What does L-Menthol do in this product?
L-Menthol is one of the two active ingredients in FDgard, but we don't have detailed data on its specific role or how well it works in this formulation.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if FDgard Caraway Oil and I-Manthol is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

FDgard Caraway Oil and I-Manthol label
Go deeper

The Full Monographs Behind FDgard Caraway Oil and I-Manthol’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Caraway

Interacts with 413 drugs

Caraway is a common cooking spice that has long been used to ease gas, bloating, and indigestion. Some evidence suggests caraway oil—often combined with peppermint oil—may help with indigest...

Read the full Caraway monograph →
Sources

Sources & How We Checked

FDgard Caraway Oil and I-Manthol's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Caraway 11 references
  1. Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
  2. May B, Kuntz HD, Kieser M, Kohler S. Efficacy of a fixed peppermint oil/caraway oil combination in non-ulcer dyspepsia. Arzneimittelforschung 1996;46:1149-53.
  3. Micklefield GH, Greving I, May B. Effects of peppermint oil and caraway oil on gastroduodenal motility. Phytother Res 2000;14:20-3. DOI
  4. Herb Info Canada. Caraway website. www.herb.plant.org/caraway.htm (Accessed 11 September 2000).
  5. May B, Kohler S, Schneider B. Efficacy and tolerability of a fixed combination of peppermint oil and caraway oil in patients suffering from functional dyspepsia. Aliment Pharmacol Ther 2000;14:1671-7. PubMed
  6. Eddouks M, Lemhardri A, Michel JB. Caraway and caper: potential anti-hyperglycaemic plants in diabetic rats. J Ethnopharmacol 2004;94:143-8. PubMed
  7. Sachin BS, Monica P, Sharma SC, et al. Pharmacokinetic interaction of some antitubercular drugs with caraway: implications in the enhancement of drug bioavailability. Hum Exp Toxicol. 2009;28(4):175-84. PubMed
  8. Lahlou, S., Tahraoui, A., Israili, Z., and Lyoussi, B. Diuretic activity of the aqueous extracts of Carum carvi and Tanacetum vulgare in normal rats. J Ethnopharmacol. 4-4-2007;110(3):458-463. PubMed
  9. de Sousa, D. P., Farias Nobrega, F. F., and de Almeida, R. N. Influence of the chirality of (R)-(-)- and (S)-(+)-carvone in the central nervous system: a comparative study. Chirality 5-5-2007;19(4):264-268.
  10. Modu S, Gohla K Umar IA. The hypoglycaemic and hypocholrsterolaemic properties of black caraway (Carum carvi L.) oil in alloxan diabetic rats. Biokemistri (Nigeria) 1997;7:91-97.
  11. Rich G, Shah A, Koloski N, et al. A randomized placebo-controlled trial on the effects of Menthacarin, a proprietary peppermint- and caraway-oil-preparation, on symptoms and quality of life in patients with functional dyspepsia. Neurogastroenterol Motil 2 PubMed

See these in context on the Caraway monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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