Fenugreek Alcohol Free Ingredients & Drug Interactions
by Hawaii Pharm
What is this page for?
First and foremost: checking Fenugreek Alcohol Free against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Fenugreek Alcohol Free is a dietary supplement by Hawaii Pharm with 1 active ingredient. Its ingredients are commonly taken for blood sugar control, boosting breast milk supply, high cholesterol.Based on those ingredients, 389 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Fenugreek Fruit Extract, Dry. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Fenugreek Alcohol Free by Hawaii Pharm
Ask about any prescription or over-the-counter medication and we check it for interactions with Fenugreek Alcohol Free by Hawaii Pharm — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Fenugreek Alcohol Free by Hawaii Pharm
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: fenugreek fruit extract in a dry form, suspended in a liquid base. The inactive ingredients are glycerin and water, which make up the liquid formulation.
Does it work?
Moderate evidence
Fenugreek is rated possibly effective for sexual dysfunction and dysmenorrhea (painful periods). It's also rated possibly effective for diabetes based on research showing it can lower fasting blood sugar and post-meal blood sugar levels.
The evidence we hold doesn't establish how strong these effects are or how they compare to other approaches—talk with your doctor or pharmacist about whether it fits your situation.
How safe is it?
Well-documented data
Fenugreek is generally well tolerated in food amounts, though supplement doses may cause side effects in some people. The most common ones are abdominal pain, bloating, diarrhea, indigestion, gas, and nausea.
Rare but serious allergic reactions—including severe swelling (angioedema), airway constriction (bronchospasm), and shock—have been reported. Some people also develop skin reactions or experience wheezing and facial swelling.
Fenugreek at medicinal doses is likely unsafe in pregnancy because it may affect the uterus. If you're pregnant, avoid supplement use.
For breastfeeding, the safety data rates it possibly safe, but evidence is limited—discuss it with your doctor or midwife before using it to boost milk supply. One known side effect: fenugreek can cause an unusual body odor in both adults and infants exposed during pregnancy, sometimes mistaken for a serious metabolic condition—but this appears to resolve without long-term harm.
Meds to double-check
Moderate interaction found
Before you start this fenugreek product, double-check these with your own doctor or pharmacist: blood thinners and antiplatelet drugs (including warfarin and clopidogrel), diabetes medications, theophylline, phenytoin, sildenafil, and metoprolol. All are rated Moderate-severity interactions.
Fenugreek may lower their effectiveness or increase side effects.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.
Fenugreek is possibly effective for sexual dysfunction, painful periods, and diabetes, but it interacts with a large number of medications—especially blood thinners, diabetes drugs, and drugs your liver clears quickly. It's likely unsafe in pregnancy.
Before taking it, talk with your doctor or pharmacist about your current medications and whether this product is right for you.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 24, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Fenugreek Alcohol Free, straight from the product label.
| Brand | Hawaii Pharm |
|---|---|
| Barcode (UPC) | 840253621764 |
| Net contents | 4 Fluid Ounce(s); 120 mL |
| Market status | On market |
| Date entered into DSLD | Aug 24, 2023 |
| DSLD ID | 300670 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Fenugreek Alcohol Free by Hawaii Pharm, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Fenugreek Fruit Extract, Dry | 1156 mg | -- |
Other ingredients: Glycerin, Water
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)
Hawaii Pharm Herbal Extract Highest quality since 2008
Suggested/Recommended/Usage/Directions
Suggested use: Shake well before using. For adults add about 20-30 drops (0.7-1 mL, one full squeeze of the dropper bulb) to some juice or water, up to 4 times a day.
Precautions
Warning: We recommend to seek expert medical advice before taking.
Do not use if you are allergic to any ingredients.
Consult your physician before giving to children under 18, during pregnancy, if nursing or taking medications.
Consult your physician before giving to children under 18, during pregnancy, if nursing or taking medications.
May affect the ability to drive and operate machinery. May have contraindications, can cause side effects and adverse reactions. Do not use if seal is broken or missing.
Keep out of the reach of children!
Storage
Store in a cool dry place.
Seals/Symbols
cGMP Made in compliance with cGMP 21 CFR 111 in an FDA registered and inspected facility.
C2H5OH Alcohol free USA Made in United States of America
FDA Disclaimer Statement
This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure or prevent any disease.
General Statements
Scan this QR-code to get 15% discount on your next purchase. Limited time deal.
Formula
Trigonella foenum-graecum
Formulation
Only natural ingredients Purity is laboratory tested and verified
All the raw materials are gluten-free by their nature No artificial colors, flavors, or preservatives
Not tested on animals
C2H5OH Alcohol free
Made in USA, Hawaii
FDA Statement of Identity
Herbal Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Fenugreek Alcohol Free by Hawaii Pharm label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Fenugreek Alcohol Free by Hawaii Pharm
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size0.7 mL Dosage formLiquid Servings per container120 Amounts shown are per serving.
Fenugreek Fruit Extract, Dry
Interacts with389 drugs
Fenugreek is a common kitchen spice that is also taken as a supplement, mainly for blood sugar, cholesterol, and to support breast milk production. So...
Fenugreek Fruit Extract, Dry monograph & interactionsOther (inactive) ingredients: Glycerin, Water. These complete the product’s ingredient list but are not active constituents.
Fenugreek Alcohol Free by Hawaii Pharm Drug Interactions
HelloPharmacist Interaction Report
Hawaii Pharm's Fenugreek Alcohol Free interacts with a substantial number of medications through its fenugreek fruit extract.
The most serious documented interaction is Moderate in severity: fenugreek may theoretically lower blood sugar (glucose) levels additively with diabetes medications, and it can reduce blood thinning (anticoagulant) or blood-clotting-prevention (antiplatelet) effects. Clinical research confirms fenugreek seed reduces fasting blood sugar and post-meal blood sugar levels in people with type 2 diabetes.
Read the full breakdown — every affected drug type, severity by severity
Additionally, fenugreek may reduce how your body processes certain drugs. It can lower theophylline levels by as much as 28%, decrease phenytoin concentrations by roughly 44%, and reduce sildenafil levels by up to 27%—all potentially weakening their effects.
It may also interfere with clopidogrel's conversion to its active form and add to blood-pressure-lowering effects when combined with metoprolol.
Finally, fenugreek may increase bleeding risk or raise INR (a blood-thinning marker) in people taking warfarin. Altogether, these interactions span 389 individual medications.
Before you start this product, check your exact medications with the search tool on this page or with your doctor or pharmacist.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Fenugreek Alcohol Free?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Fenugreek Alcohol Free interact with 389 drugs. Click any drug to see the details.
1 of the 1 ingredient in Fenugreek Alcohol Free interact with drugs. Each result below shows which ingredient is responsible. Fenugreek Fruit Extract, Dry
AbciximabReoPro
How Abciximab interacts with Fenugreek Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Fruit Extract, DryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Fruit Extract, Dry + Abciximab interactionAbrocitinibCibinqo
How Abrocitinib interacts with Fenugreek Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Fruit Extract, DryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Fruit Extract, Dry + Abrocitinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Fenugreek Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Fruit Extract, DryAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, fenugreek seed might have additive hypoglycemic effects when used with antidiabetes drugs.
Read the full Fenugreek Fruit Extract, Dry + Acarbose interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Fenugreek Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Fruit Extract, DryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Fruit Extract, Dry + Acenocoumarol interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Fenugreek Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Fruit Extract, DryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Fruit Extract, Dry + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Fenugreek Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Fruit Extract, DryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Fruit Extract, Dry + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with Fenugreek Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Fruit Extract, DryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Fruit Extract, Dry + Acetaminophen, Ibuprofen interactionAcetohexamideDymelor
How Acetohexamide interacts with Fenugreek Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Fruit Extract, DryAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, fenugreek seed might have additive hypoglycemic effects when used with antidiabetes drugs.
Read the full Fenugreek Fruit Extract, Dry + Acetohexamide interactionAcetylsalicylic AcidEntrophen
How Acetylsalicylic Acid interacts with Fenugreek Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Fruit Extract, DryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Fruit Extract, Dry + Acetylsalicylic Acid interactionAlbiglutideTanzeum
How Albiglutide interacts with Fenugreek Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Fruit Extract, DryAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, fenugreek seed might have additive hypoglycemic effects when used with antidiabetes drugs.
Read the full Fenugreek Fruit Extract, Dry + Albiglutide interactionAlogliptinNesina
How Alogliptin interacts with Fenugreek Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Fruit Extract, DryAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, fenugreek seed might have additive hypoglycemic effects when used with antidiabetes drugs.
Read the full Fenugreek Fruit Extract, Dry + Alogliptin interactionAlogliptin, MetforminKazano
How Alogliptin, Metformin interacts with Fenugreek Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Fruit Extract, DryAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, fenugreek seed might have additive hypoglycemic effects when used with antidiabetes drugs.
Read the full Fenugreek Fruit Extract, Dry + Alogliptin, Metformin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with Fenugreek Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Fruit Extract, DryAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, fenugreek seed might have additive hypoglycemic effects when used with antidiabetes drugs.
Read the full Fenugreek Fruit Extract, Dry + Alogliptin, Pioglitazone interactionAlteplase, TpaActilyse, Activase
How Alteplase, Tpa interacts with Fenugreek Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Fruit Extract, DryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Fruit Extract, Dry + Alteplase, Tpa interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with Fenugreek Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Fruit Extract, DryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Fruit Extract, Dry + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
How Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interacts with Fenugreek Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Fruit Extract, DryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Fruit Extract, Dry + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAnacaulase-bcdbNexoBrid
How Anacaulase-bcdb interacts with Fenugreek Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Fruit Extract, DryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Fruit Extract, Dry + Anacaulase-bcdb interactionAnagrelideAgrylin
How Anagrelide interacts with Fenugreek Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Fruit Extract, DryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Fruit Extract, Dry + Anagrelide interactionAnisindioneMiradon
How Anisindione interacts with Fenugreek Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Fruit Extract, DryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Fruit Extract, Dry + Anisindione interactionAntidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) InhibitorGlyxambi
How Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interacts with Fenugreek Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Fruit Extract, DryAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, fenugreek seed might have additive hypoglycemic effects when used with antidiabetes drugs.
Read the full Fenugreek Fruit Extract, Dry + Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interactionAntithrombin IiiThrombate III
How Antithrombin Iii interacts with Fenugreek Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Fruit Extract, DryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Fruit Extract, Dry + Antithrombin Iii interactionApixabanEliquis
How Apixaban interacts with Fenugreek Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Fruit Extract, DryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Fruit Extract, Dry + Apixaban interactionArgatrobanArgatroban
How Argatroban interacts with Fenugreek Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Fruit Extract, DryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Fruit Extract, Dry + Argatroban interactionAspirinAngettes 75, ASA, Asaphen, Aspirin, Caprin, Cartia +8 more
How Aspirin interacts with Fenugreek Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Fruit Extract, DryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Fruit Extract, Dry + Aspirin interactionAspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #3
How Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium Hydroxide interacts with Fenugreek Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Fruit Extract, DryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Fruit Extract, Dry + Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium Hydroxide interactionAspirin, ButalbitalAxotal
How Aspirin, Butalbital interacts with Fenugreek Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Fruit Extract, DryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Fruit Extract, Dry + Aspirin, Butalbital interactionAspirin, Butalbital, CaffeineFiorinal
How Aspirin, Butalbital, Caffeine interacts with Fenugreek Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Fruit Extract, DryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Fruit Extract, Dry + Aspirin, Butalbital, Caffeine interactionAspirin, Butalbital, Caffeine, Codeine PhosphateFiorinal w/ Codeine
How Aspirin, Butalbital, Caffeine, Codeine Phosphate interacts with Fenugreek Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Fruit Extract, DryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Fruit Extract, Dry + Aspirin, Butalbital, Caffeine, Codeine Phosphate interactionAspirin, Butalbital, Caffeine, PhenacetinMarnal
How Aspirin, Butalbital, Caffeine, Phenacetin interacts with Fenugreek Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Fruit Extract, DryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Fruit Extract, Dry + Aspirin, Butalbital, Caffeine, Phenacetin interactionAspirin, CaffeineAnacin
How Aspirin, Caffeine interacts with Fenugreek Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek Fruit Extract, DryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek Fruit Extract, Dry + Aspirin, Caffeine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Fenugreek Alcohol Free with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Fenugreek Fruit Extract, Dry
Anticoagulant/Antiplatelet Drugs
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Some of the constituents in fenugreek have antiplatelet effects in animal and in vitro research. However, common fenugreek products might not contain sufficient concentrations of these constituents for clinical effects. A clinical study in patients with coronary artery disease or diabetes shows that taking fenugreek seed powder 2.5 grams twice daily for 3 months does not affect platelet aggregation, fibrinolytic activity, or fibrinogen levels .
Antidiabetes Drugs
Theoretically, fenugreek seed might have additive hypoglycemic effects when used with antidiabetes drugs.
Clinical research shows that fenugreek seed can reduce fasting blood glucose and 2-hour postprandial glucose levels in adults with type 2 diabetes.
Clopidogrel (Plavix)
Theoretically, fenugreek seed might alter the clinical effects of clopidogrel by inhibiting its conversion to the active form.
Animal research shows that fenugreek seed 200 mg/kg daily for 14 days increases the maximum serum concentration of clopidogrel by 21%. It is unclear how this affects the pharmacokinetics of the active metabolite of clopidogrel; however, this study found that concomitant use of fenugreek seed and clopidogrel prolonged bleeding time by an additional 11%.
Metoprolol (Toprol)
Theoretically, fenugreek seed might have additive hypotensive effects when used with metoprolol.
Animal research shows that fenugreek seed 300 mg/kg daily for 2 weeks decreases systolic and diastolic blood pressure by 9% and 11%, respectively, when administered alone, and by 15% and 22%, respectively, when given with metoprolol 10 mg/kg.
Phenytoin (Dilantin)
Theoretically, fenugreek might decrease plasma levels of phenytoin.
Animal research shows that taking fenugreek seeds for 1 week decreases maximum concentrations and the area under the curve of a single dose of phenytoin by 44% and 72%, respectively. This seems to be related to increased clearance. So far, this interaction has not been reported in humans.
Sildenafil (Viagra)
Theoretically, concurrent use of sildenafil and fenugreek might reduce levels and therapeutic effects of sildenafil.
Animal research shows that taking fenugreek seeds for 1 week reduces maximum concentrations and the area under the curve of a single dose of sildenafil by 27% and 48%, respectively. So far, this interaction has not been reported in humans.
Theophylline
Theoretically, fenugreek may reduce the levels and clinical effects of theophylline.
Animal research shows that fenugreek 50 grams daily for 7 days reduces the maximum serum concentration (Cmax) of theophylline by 28% and the area under the plasma drug concentration-time curve (AUC) by 22%.
Warfarin (Coumadin)
Theoretically, fenugreek might have additive effects with warfarin and increase the international normalized ratio (INR).
Some fenugreek constituents have antiplatelet effects, although these might not be present in concentrations that are clinically significant. In one case report, a patient taking warfarin experienced an increased INR when starting to take fenugreek in combination with boldo.
Antihypertensive Drugs
Fenugreek may also have an additive effect on blood pressure-lowering medications. Studies on animals have shown that fenugreek seed can decrease both systolic and diastolic blood pressure by up to 22% when combined with metoprolol. Therefore, it is essential to monitor your blood pressure regularly if you are taking fenugreek and metoprolol together or any other antihypertensive drugs.
Brand information
Manufacturer and brand details for Fenugreek Alcohol Free, from the product label.
Hawaii Pharm
See all Hawaii Pharm products- Name
- Hawaii Pharm LLC
- Street Address
- 510 Sumner St. Ste. 613
- City
- Honolulu
- State
- HI
- ZipCode
- 96817
- Phone Number
- 888-854-2924
- Web Address
- www.hawaiipharm.com
Fenugreek Alcohol Free by Hawaii Pharm: Common Questions
Does Fenugreek Alcohol Free by Hawaii Pharm interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Will fenugreek help my blood sugar if I take diabetes medication?
Can I take this if I'm on a blood thinner like warfarin?
Is fenugreek safe to use while pregnant?
Can I use fenugreek while breastfeeding?
What are the common side effects?
Is there anything else in this product besides fenugreek?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Fenugreek Alcohol Free is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Fenugreek Alcohol Free’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Fenugreek Alcohol Free's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 30 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Fenugreek 30 references
- Madar Z, Thorne R. Dietary fiber. Prog Food Nutr Sci 1987;11:153-74.
- Sharma RD, Raghuram TC, Rao NS. Effect of fenugreek seeds on blood glucose and serum lipids in type I diabetes. Eur J Clin Nutr 1990;44:301-6.
- Patil SP, Niphadkar PV, Bapat MM. Allergy to fenugreek (Trigonella foenum graecum). Ann Allergy Asthma Immunol 1997;78:297-300. PubMed
- Lambert J, Cormier J. Potential interaction between warfarin and boldo-fenugreek. Pharmacotherapy 2001;21:509-12. PubMed
- Bordia A, Verma SK, Srivastava KC. Effect of ginger (Zingiber officinale Rosc.) and fenugreek (Trigonella foenumgraecum L.) on blood lipids, blood sugar and platelet aggregation in patients with coronary artery disease. Prostaglandins Leukot Essent Fatty PubMed
- Yalcin SS, Tekinalp G, Ozalp I. Peculiar odor of traditional food and maple syrup urine disease. Pediatr Int 1999;41:108-9. PubMed
- Sewell AC, Mosandl A, Bohles H. False diagnosis of maple syrup urine disease owing to ingestion of herbal tea. N Engl J Med 1999;341:769.. PubMed
- Abdo MS, al-Kafawi AA. Experimental studies on the effect of Trigonella foenum-graecum (abstract). Planta Med 1969;17:14-8.
- Gupta A, Gupta R, Lal B. Effect of Trigonella foenum-graecum (fenugreek) seeds on glycaemic control and insulin resistance in type 2 diabetes mellitus: a double blind placebo controlled study. J Assoc Physicians India 2001;49:1057-61.
- Gabay MP. Galactogogues: medications that induce lactation. J Hum Lact 2002;18:274-9. PubMed
- Chevassus H, Gaillard JB, Farret A, et al. A fenugreek seed extract selectively reduces spontaneous fat intake in overweight subjects. Eur J Clin Pharmacol 2010;66(5):449-55. PubMed
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