Fenugreek Extra Strength 2400 mg Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Fenugreek Extra Strength 2400 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Fenugreek Extra Strength 2400 mg is a dietary supplement by Futurebiotics with 1 active ingredient. Its ingredients are commonly taken for blood sugar control, boosting breast milk supply, high cholesterol.Based on those ingredients, 389 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Fenugreek, Powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Fenugreek Extra Strength 2400 mg by Futurebiotics
Ask about any prescription or over-the-counter medication and we check it for interactions with Fenugreek Extra Strength 2400 mg by Futurebiotics — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Fenugreek Extra Strength 2400 mg by Futurebiotics
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: fenugreek seed extract at 2400 mg per serving. Fenugreek is the seed of a plant used traditionally in cooking and herbal medicine, and research suggests it may have effects on blood sugar, blood flow, and reproductive health.
The capsule also contains inactive ingredients — microcrystalline cellulose, modified cellulose, magnesium stearate, and silicon dioxide — which are binders, fillers, and flow agents common in supplement capsules.
Does it work?
Moderate evidence
The evidence for fenugreek in this product is modest. Research rates it possibly effective for sexual dysfunction and sexual arousal, possibly effective for dysmenorrhea (period pain), and possibly effective for type 2 diabetes. 'Possibly effective' means there's some clinical support, but the evidence isn't definitive.
If you're considering it for any of these uses, talk with your doctor or pharmacist about what the data actually shows and whether it makes sense for your situation.
How safe is it?
Well-documented data
Fenugreek seed is generally well tolerated in food amounts, but supplement doses — like what's in this product — can cause side effects. The most common are abdominal pain, bloating, diarrhea, indigestion, gas, nausea, and low blood sugar (hypoglycemia).
Rare but serious allergic reactions including severe swelling, difficulty breathing, and shock have been reported. Don't use medicinal amounts of fenugreek during pregnancy — it may affect the uterus.
If you're breastfeeding and interested in fenugreek to boost milk supply, the evidence is limited; talk with your doctor or lactation consultant first. Taking fenugreek near delivery may cause a distinctive body odor in newborns that could be confused with a serious metabolic condition, though the odor doesn't appear to cause lasting harm.
Meds to double-check
Moderate interaction found
Before you take this product, check with your pharmacist if you're on blood thinners or antiplatelet drugs (like warfarin or clopidogrel), diabetes medications, theophylline, phenytoin (Dilantin), sildenafil (Viagra), or metoprolol (Toprol). All of these have documented Moderate interactions with fenugreek, and your pharmacist can tell you whether it's safe for your specific situation.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Fenugreek Extra Strength may be worth considering if you're interested in its effects on blood sugar or sexual function, but it's not for everyone. If you take any prescription medication — especially blood thinners, diabetes drugs, theophylline, phenytoin, sildenafil, or metoprolol — check with your pharmacist first.
Pregnant women should avoid it.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 25, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Fenugreek Extra Strength 2400 mg, straight from the product label.
| Brand | Futurebiotics |
|---|---|
| Barcode (UPC) | X003KDL47X |
| Net contents | 300 Vegetarian Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Mar 25, 2025 |
| DSLD ID | 321922 |
| Product type | Botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Women (not pregnant or lactating) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Fenugreek Extra Strength 2400 mg by Futurebiotics, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Fenugreek seed extract | 240 mg | -- |
| Fenugreek, Powder | 2400 mg | -- |
Other ingredients: Microcrystalline Cellulose, Modified Cellulose, Magnesium Stearate, Silicon Dioxide
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Formulation
Supports overall good health & well-being
Soy-free Lab tested GMO free
Formula
Traditional Herb
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Directions: As a dietary supplement for adults, take 2 capsules daily, preferably with a meal or as directed by a healthcare professional.
Precautions
Warnings: Do not take this product if you are pregnant or nursing. Consult a healthcare professional before taking this product if you have a medical condition, or are taking any medications.
Discontinue use and consult a healthcare professional in case of adverse reaction. Do not use if seal under cap is broken or missing.
Keep out of reach of children.
Storage
Protect from light.
Seals/Symbols
Lab Tested GMO free
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Fenugreek Extra Strength 2400 mg by Futurebiotics label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Fenugreek Extra Strength 2400 mg by Futurebiotics
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size2 Capsule(s) Dosage formCapsule Servings per container150 Amounts shown are per serving.
Fenugreek, Powder
Interacts with389 drugs
Fenugreek is a common kitchen spice that is also taken as a supplement, mainly for blood sugar, cholesterol, and to support breast milk production. So...
Fenugreek, Powder monograph & interactionsOther (inactive) ingredients: Microcrystalline Cellulose, Modified Cellulose, Magnesium Stearate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.
Fenugreek Extra Strength 2400 mg by Futurebiotics Drug Interactions
HelloPharmacist Interaction Report
Fenugreek Extra Strength 2400 mg by Futurebiotics has documented interactions with a number of common medications.
The most serious concern is with blood thinners (anticoagulants) and antiplatelet drugs like clopidogrel (Plavix) and warfarin (Coumadin) — fenugreek might add to their effects or change how they work, potentially raising bleeding risk.
Read the full breakdown — every affected drug type, severity by severity
Fenugreek also interacts with diabetes medications. It can lower blood sugar on its own, so taking it alongside antidiabetes drugs could push your glucose too low.
You'll want to monitor closely if you're on insulin or oral diabetes medications.
Additionally, this supplement may reduce levels of several other drugs: theophylline (a breathing medication), phenytoin (an antiseizure drug), and sildenafil (Viagra). It could also have additive blood pressure–lowering effects with metoprolol (a beta-blocker).
All of these interactions are rated Moderate.
Altogether, these interactions span 386 individual medications. Before you start fenugreek, run your exact medications through the checker below — it's the only way to know if any of yours are on this list.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Fenugreek Extra Strength 2400 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Fenugreek Extra Strength 2400 mg interact with 389 drugs. Click any drug to see the details.
1 of the 1 ingredient in Fenugreek Extra Strength 2400 mg interact with drugs. Each result below shows which ingredient is responsible. Fenugreek, Powder
AbciximabReoPro
How Abciximab interacts with Fenugreek Extra Strength 2400 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek, Powder + Abciximab interactionAbrocitinibCibinqo
How Abrocitinib interacts with Fenugreek Extra Strength 2400 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek, Powder + Abrocitinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Fenugreek Extra Strength 2400 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek, PowderAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, fenugreek seed might have additive hypoglycemic effects when used with antidiabetes drugs.
Read the full Fenugreek, Powder + Acarbose interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Fenugreek Extra Strength 2400 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek, Powder + Acenocoumarol interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Fenugreek Extra Strength 2400 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek, Powder + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Fenugreek Extra Strength 2400 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek, Powder + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with Fenugreek Extra Strength 2400 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek, Powder + Acetaminophen, Ibuprofen interactionAcetohexamideDymelor
How Acetohexamide interacts with Fenugreek Extra Strength 2400 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek, PowderAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, fenugreek seed might have additive hypoglycemic effects when used with antidiabetes drugs.
Read the full Fenugreek, Powder + Acetohexamide interactionAcetylsalicylic AcidEntrophen
How Acetylsalicylic Acid interacts with Fenugreek Extra Strength 2400 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek, Powder + Acetylsalicylic Acid interactionAlbiglutideTanzeum
How Albiglutide interacts with Fenugreek Extra Strength 2400 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek, PowderAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, fenugreek seed might have additive hypoglycemic effects when used with antidiabetes drugs.
Read the full Fenugreek, Powder + Albiglutide interactionAlogliptinNesina
How Alogliptin interacts with Fenugreek Extra Strength 2400 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek, PowderAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, fenugreek seed might have additive hypoglycemic effects when used with antidiabetes drugs.
Read the full Fenugreek, Powder + Alogliptin interactionAlogliptin, MetforminKazano
How Alogliptin, Metformin interacts with Fenugreek Extra Strength 2400 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek, PowderAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, fenugreek seed might have additive hypoglycemic effects when used with antidiabetes drugs.
Read the full Fenugreek, Powder + Alogliptin, Metformin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with Fenugreek Extra Strength 2400 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek, PowderAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, fenugreek seed might have additive hypoglycemic effects when used with antidiabetes drugs.
Read the full Fenugreek, Powder + Alogliptin, Pioglitazone interactionAlteplase, TpaActilyse, Activase
How Alteplase, Tpa interacts with Fenugreek Extra Strength 2400 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek, Powder + Alteplase, Tpa interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with Fenugreek Extra Strength 2400 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek, Powder + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
How Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interacts with Fenugreek Extra Strength 2400 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek, Powder + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAnacaulase-bcdbNexoBrid
How Anacaulase-bcdb interacts with Fenugreek Extra Strength 2400 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek, Powder + Anacaulase-bcdb interactionAnagrelideAgrylin
How Anagrelide interacts with Fenugreek Extra Strength 2400 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek, Powder + Anagrelide interactionAnisindioneMiradon
How Anisindione interacts with Fenugreek Extra Strength 2400 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek, Powder + Anisindione interactionAntidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) InhibitorGlyxambi
How Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interacts with Fenugreek Extra Strength 2400 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek, PowderAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, fenugreek seed might have additive hypoglycemic effects when used with antidiabetes drugs.
Read the full Fenugreek, Powder + Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interactionAntithrombin IiiThrombate III
How Antithrombin Iii interacts with Fenugreek Extra Strength 2400 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek, Powder + Antithrombin Iii interactionApixabanEliquis
How Apixaban interacts with Fenugreek Extra Strength 2400 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek, Powder + Apixaban interactionArgatrobanArgatroban
How Argatroban interacts with Fenugreek Extra Strength 2400 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek, Powder + Argatroban interactionAspirinAngettes 75, ASA, Asaphen, Aspirin, Caprin, Cartia +8 more
How Aspirin interacts with Fenugreek Extra Strength 2400 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek, Powder + Aspirin interactionAspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #3
How Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium Hydroxide interacts with Fenugreek Extra Strength 2400 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek, Powder + Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium Hydroxide interactionAspirin, ButalbitalAxotal
How Aspirin, Butalbital interacts with Fenugreek Extra Strength 2400 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek, Powder + Aspirin, Butalbital interactionAspirin, Butalbital, CaffeineFiorinal
How Aspirin, Butalbital, Caffeine interacts with Fenugreek Extra Strength 2400 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek, Powder + Aspirin, Butalbital, Caffeine interactionAspirin, Butalbital, Caffeine, Codeine PhosphateFiorinal w/ Codeine
How Aspirin, Butalbital, Caffeine, Codeine Phosphate interacts with Fenugreek Extra Strength 2400 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek, Powder + Aspirin, Butalbital, Caffeine, Codeine Phosphate interactionAspirin, Butalbital, Caffeine, PhenacetinMarnal
How Aspirin, Butalbital, Caffeine, Phenacetin interacts with Fenugreek Extra Strength 2400 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek, Powder + Aspirin, Butalbital, Caffeine, Phenacetin interactionAspirin, CaffeineAnacin
How Aspirin, Caffeine interacts with Fenugreek Extra Strength 2400 mg — through 1 ingredient. Tap an ingredient for the detail:
Fenugreek, PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Read the full Fenugreek, Powder + Aspirin, Caffeine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Fenugreek Extra Strength 2400 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Fenugreek, Powder
Anticoagulant/Antiplatelet Drugs
Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Some of the constituents in fenugreek have antiplatelet effects in animal and in vitro research. However, common fenugreek products might not contain sufficient concentrations of these constituents for clinical effects. A clinical study in patients with coronary artery disease or diabetes shows that taking fenugreek seed powder 2.5 grams twice daily for 3 months does not affect platelet aggregation, fibrinolytic activity, or fibrinogen levels .
Antidiabetes Drugs
Theoretically, fenugreek seed might have additive hypoglycemic effects when used with antidiabetes drugs.
Clinical research shows that fenugreek seed can reduce fasting blood glucose and 2-hour postprandial glucose levels in adults with type 2 diabetes.
Clopidogrel (Plavix)
Theoretically, fenugreek seed might alter the clinical effects of clopidogrel by inhibiting its conversion to the active form.
Animal research shows that fenugreek seed 200 mg/kg daily for 14 days increases the maximum serum concentration of clopidogrel by 21%. It is unclear how this affects the pharmacokinetics of the active metabolite of clopidogrel; however, this study found that concomitant use of fenugreek seed and clopidogrel prolonged bleeding time by an additional 11%.
Metoprolol (Toprol)
Theoretically, fenugreek seed might have additive hypotensive effects when used with metoprolol.
Animal research shows that fenugreek seed 300 mg/kg daily for 2 weeks decreases systolic and diastolic blood pressure by 9% and 11%, respectively, when administered alone, and by 15% and 22%, respectively, when given with metoprolol 10 mg/kg.
Phenytoin (Dilantin)
Theoretically, fenugreek might decrease plasma levels of phenytoin.
Animal research shows that taking fenugreek seeds for 1 week decreases maximum concentrations and the area under the curve of a single dose of phenytoin by 44% and 72%, respectively. This seems to be related to increased clearance. So far, this interaction has not been reported in humans.
Sildenafil (Viagra)
Theoretically, concurrent use of sildenafil and fenugreek might reduce levels and therapeutic effects of sildenafil.
Animal research shows that taking fenugreek seeds for 1 week reduces maximum concentrations and the area under the curve of a single dose of sildenafil by 27% and 48%, respectively. So far, this interaction has not been reported in humans.
Theophylline
Theoretically, fenugreek may reduce the levels and clinical effects of theophylline.
Animal research shows that fenugreek 50 grams daily for 7 days reduces the maximum serum concentration (Cmax) of theophylline by 28% and the area under the plasma drug concentration-time curve (AUC) by 22%.
Warfarin (Coumadin)
Theoretically, fenugreek might have additive effects with warfarin and increase the international normalized ratio (INR).
Some fenugreek constituents have antiplatelet effects, although these might not be present in concentrations that are clinically significant. In one case report, a patient taking warfarin experienced an increased INR when starting to take fenugreek in combination with boldo.
Antihypertensive Drugs
Fenugreek may also have an additive effect on blood pressure-lowering medications. Studies on animals have shown that fenugreek seed can decrease both systolic and diastolic blood pressure by up to 22% when combined with metoprolol. Therefore, it is essential to monitor your blood pressure regularly if you are taking fenugreek and metoprolol together or any other antihypertensive drugs.
Brand information
Manufacturer and brand details for Fenugreek Extra Strength 2400 mg, from the product label.
Futurebiotics
See all Futurebiotics products- Name
- Futurebiotics
- City
- Hauppauge
- State
- NY
- ZipCode
- 11788
- Phone Number
- (800) 367-5433
- Web Address
- www.futurebiotics.com
Fenugreek Extra Strength 2400 mg by Futurebiotics: Common Questions
Does Fenugreek Extra Strength 2400 mg by Futurebiotics interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What does fenugreek actually do?
What are the most common side effects?
Can I take this if I'm pregnant?
Could this cause an allergic reaction?
Can I use this alongside blood thinners like warfarin?
Will this lower my blood sugar if I have diabetes?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Fenugreek Extra Strength 2400 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Fenugreek Extra Strength 2400 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Fenugreek Extra Strength 2400 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 30 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Fenugreek 30 references
- Madar Z, Thorne R. Dietary fiber. Prog Food Nutr Sci 1987;11:153-74.
- Sharma RD, Raghuram TC, Rao NS. Effect of fenugreek seeds on blood glucose and serum lipids in type I diabetes. Eur J Clin Nutr 1990;44:301-6.
- Patil SP, Niphadkar PV, Bapat MM. Allergy to fenugreek (Trigonella foenum graecum). Ann Allergy Asthma Immunol 1997;78:297-300. PubMed
- Lambert J, Cormier J. Potential interaction between warfarin and boldo-fenugreek. Pharmacotherapy 2001;21:509-12. PubMed
- Bordia A, Verma SK, Srivastava KC. Effect of ginger (Zingiber officinale Rosc.) and fenugreek (Trigonella foenumgraecum L.) on blood lipids, blood sugar and platelet aggregation in patients with coronary artery disease. Prostaglandins Leukot Essent Fatty PubMed
- Yalcin SS, Tekinalp G, Ozalp I. Peculiar odor of traditional food and maple syrup urine disease. Pediatr Int 1999;41:108-9. PubMed
- Sewell AC, Mosandl A, Bohles H. False diagnosis of maple syrup urine disease owing to ingestion of herbal tea. N Engl J Med 1999;341:769.. PubMed
- Abdo MS, al-Kafawi AA. Experimental studies on the effect of Trigonella foenum-graecum (abstract). Planta Med 1969;17:14-8.
- Gupta A, Gupta R, Lal B. Effect of Trigonella foenum-graecum (fenugreek) seeds on glycaemic control and insulin resistance in type 2 diabetes mellitus: a double blind placebo controlled study. J Assoc Physicians India 2001;49:1057-61.
- Gabay MP. Galactogogues: medications that induce lactation. J Hum Lact 2002;18:274-9. PubMed
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