Interactions on record — worth a quick check against your medications. Based on 7 of 11 ingredients. Check your meds →
Dietary supplement

FiberMax Caps Ingredients & Drug Interactions

by Advanced Naturals

FiberMax Caps label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking FiberMax Caps against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

FiberMax Caps is a dietary supplement by Advanced Naturals with 11 active ingredients. Its ingredients are commonly taken for constipation, diarrhea, high cholesterol.Based on those ingredients, 2,153 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Marshmallow, Dietary Fiber, Guar Gum. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against FiberMax Caps by Advanced Naturals

Ask about any prescription or over-the-counter medication and we check it for interactions with FiberMax Caps by Advanced Naturals — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of FiberMax Caps by Advanced Naturals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 1 of its 12 active ingredients.
  • “Probiotic Blend” is a proprietary blend — the label doesn't break down how much of each component you get.
  • “FiberMax Blend” is a proprietary blend — the label gives one combined amount (3,200 mg) without saying how much of each component you get.

FiberMax Caps contains 13 ingredients, including multiple sources of fiber and probiotics aimed at digestive support. The active ingredients are L-glutamine (an amino acid), soluble and insoluble fiber for bulk, slippery elm inner bark, marshmallow root, two probiotic bacteria (Bifidobacterium bifidum and Lactobacillus acidophilus), fennel seed, fructooligosaccharides (FOS), triphala (a traditional herbal blend), Bifidobacterium infantis, organic flax, and guar gum.

The product is encased in a vegetable capsule.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: optimal digestion and healthy bowel function.
  • We looked for evidence on: Antibiotic-associated diarrhea, Antiretroviral-associated diarrhea, Chemotherapy-induced diarrhea, Clostridioides difficile infection, Colic, Constipation — and 4 related terms.
  • The strongest evidence on file: Black Psyllium is rated "Effective" for Constipation (Natural Medicines).
  • Also on file: Lactobacillus Acidophilus is rated "Possibly Effective" for Antibiotic-associated diarrhea.
  • Also on file: Guar Gum is rated "Possibly Effective" for Constipation.

The evidence for these ingredients is mixed. L-glutamine is rated effective for sickle cell disease and possibly effective for HIV-related wasting, postoperative recovery, and critical illness.

Both probiotics — L. acidophilus and B. bifidum — are possibly effective for irritable bowel syndrome; L. acidophilus is also possibly effective for H. pylori, antibiotic-associated diarrhea, and bacterial vaginosis. Guar gum is possibly effective for high blood pressure, high cholesterol, IBS, and constipation.

Fennel is possibly effective for period pain. For the other ingredients — slippery elm, marshmallow, FOS, triphala, B. infantis, and organic flax — the evidence in our data is insufficient to rate their effectiveness, or no rating is held.

The evidence, ingredient by ingredient Black Psyllium Glutamine Slippery Elm Marshmallow Fennel Lactobacillus Acidophilus Guar Gum

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 7 of the 8 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 8 of 8.
  • General safety write-ups exist for 8 of 8.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

L-glutamine is rated likely safe in pregnancy but should be used only under medical supervision in people with kidney or liver disease, and should be avoided in supplemental doses while breastfeeding unless a doctor recommends it. B. bifidum is possibly safe in pregnancy and generally well tolerated in healthy people, though those with weakened immune systems should be cautious.

L. acidophilus is possibly safe in pregnancy and generally well tolerated in healthy adults. Marshmallow is possibly unsafe in pregnancy and should be avoided while breastfeeding due to insufficient safety data.

Fennel is rated possibly unsafe in pregnancy and possibly unsafe while breastfeeding. Guar gum is possibly safe in pregnancy but must be taken with plenty of water to avoid choking or intestinal blockage; common side effects include bloating, gas, and diarrhea.

Slippery elm should be used cautiously during pregnancy and breastfeeding because safety data are limited. L-glutamine may cause belching, bloating, constipation, diarrhea, nausea, vomiting, and gastrointestinal pain at higher doses; a small number of people have reported dizziness or headache.

Fennel can cause gastrointestinal discomfort, photosensitivity, or allergic reactions; rare serious reactions include seizures or bronchial asthma. Guar gum may cause abdominal cramps, heartburn, or loose stools; rare serious effects include bowel obstruction if taken with insufficient water.

Probiotics may cause bloating, flatulence, or other mild gastrointestinal effects in some users.

Side effects, ingredient by ingredient Black Psyllium Glutamine Slippery Elm Marshmallow Fennel Lactobacillus Acidophilus Guar Gum

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 8 of the 8 matched ingredients can interact with medications — Black Psyllium, Fennel, Marshmallow, Lactobacillus Acidophilus, Glutamine, among others.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; seizure medications; heart-rhythm medications; lithium.
  • For scale: 2,154 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking FiberMax Caps, double-check moderate-severity interactions with hormonal birth control and hormone therapy (fennel), blood thinners (fennel and marshmallow), antibiotics including ciprofloxacin and penicillin (fennel and both probiotics), anticonvulsants or seizure drugs (L-glutamine), lithium (marshmallow), diabetes medications like metformin (guar gum), digoxin (guar gum), and cancer drugs like tamoxifen (fennel). Space any oral medication 30–60 minutes from this product if you take penicillin, metformin, ciprofloxacin, or other oral drugs affected by slippery elm, marshmallow, or guar gum.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

FiberMax Caps is a multi-ingredient fiber and probiotic supplement with several notable medication interactions, especially with birth control, hormone replacement, blood thinners, antibiotics, and certain other drugs. If you take any prescription medication — particularly anticonvulsants, lithium, diabetes drugs, or any hormone-based therapy — check your exact medications with the tool on this page before starting.

Talk with your pharmacist or doctor about whether the timing of doses or the product itself makes sense for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 8 of 12 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated May 24, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about FiberMax Caps, straight from the product label.

Brand Advanced Naturals
Barcode (UPC) 631257535658
Net contents 200 Vegetable Capsule(s)
Market status Off market
Date entered into DSLD May 24, 2018
DSLD ID 176838
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for FiberMax Caps by Advanced Naturals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
4 Capsule(s)
Maximum serving Sizes:
4 Capsule(s)
Servings per container
50
UPC/BARCODE
631257535658
IngredientAmount% DV
Calories15 Calorie(s)--
Total Carbohydrates2 Gram(s)1%
L-Glutamine0 NP--
Dietary Fiber1 Gram(s)4%
Protein1 Gram(s)2%
Soluble Fiber0.25 Gram(s)--
Insoluble Fiber0.75 Gram(s)--
Slippery Elm0 NP--
Marshmallow0 NP--
B. bifidum0 NP--
Fennel0 NP--
L. acidophilus0 NP--
FOS0 NP--
Triphala0 NP--
B. infantis0 NP--
Probiotic Blend0 NP--
organic Flax0 NP--
Guar Gum0 NP--
FiberMax Blend3200 mg--

Other ingredients: Vegetable Capsule

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

FiberMax is an advanced daily fiber supplement with added ingredients for optimal digestion and healthy bowel function.

Quality, purity, and potency guaranteed through expiration.

Manufactured in USA in a GMP facility.

Packed by weight, not volume. Contents may settle during storage and handling.

Natural digestive care

Promotes regularity Supports intestinal health

Not a significant source of saturated fat or cholesterol.

Formula

It contains: Organic Flax fiber, FOS, L-Glutamine, and probiotics.

Advanced fiber for sensitive colons

May contain mild traces of milk proteins from fermentation ingredients.

Formulation

Gluten free Soy free No artificial ingredients

Gluten free & psyllium free

Storage

Store in a dry place at 59-86 degrees F (15-30 degrees C).

Precautions

Keep out of reach of children.

Consult your healthcare professional before using this or any product if you are pregnant, nursing, trying to conceive, taking medication, or have a medical condition.

Notice: Using this supplement without at least a full glass of liquid may cause choking. Do not use this supplement if you have difficulty in swallowing, acute cough, or obstructed bowel.

Tamper evident: Do not use if safety seal is broken or missing.

May contain mild traces of milk proteins from fermentation ingredients.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

General

#16903 021115 90542B

FDA Statement of Identity

Fiber Supplement

Suggested/Recommended/Usage/Directions

Directions: Take 4 capsules in the morning with 8 oz. of water. May be repeated at midday and in the evening. Drink plenty of water while using this product.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

FiberMax Caps by Advanced Naturals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

FiberMax Caps label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in FiberMax Caps by Advanced Naturals

These are the 11 active ingredients this product is made of. Select any to open its full monograph.

Serving size4 Capsule(s) Dosage formCapsule Servings per container50 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Dietary Fiber

Interacts with
2,025 drugs
1 Gram(s) per serving

Black psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. I...

Dietary Fiber monograph & interactions
  • › Soluble Fiber
  • › Insoluble Fiber

Protein

1 Gram(s) per serving

FiberMax Blend

3200 mg per serving

Other (inactive) ingredients: Vegetable Capsule. These complete the product’s ingredient list but are not active constituents.

Interaction report

FiberMax Caps by Advanced Naturals Drug Interactions

Want to check YOUR meds against FiberMax Caps?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
2,153Drugs
2,153 Moderate

Ingredients driving the most interactions

Marshmallow 2,040
Dietary Fiber 2,025
Guar Gum 2,025
Slippery Elm 2,022
Fennel 740

Individual Drug Interactions

The ingredients in FiberMax Caps interact with 2,153 drugs. Click any drug to see the details.

7 of the 11 ingredients in FiberMax Caps interact with drugs. Each result below shows which ingredient is responsible. Marshmallow Dietary Fiber Guar Gum Slippery Elm Fennel Probiotic Blend L-Glutamine

Each ingredient & the kinds of drugs it affects

For each ingredient in FiberMax Caps with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Marshmallow3 drug types · 2,040 drugs

Lithium

Theoretically, due to potential diuretic effects, marshmallow might reduce excretion and increase levels of lithium.
Marshmallow is thought to have diuretic properties. To avoid lithium toxicity, the dose of lithium might need to be decreased when used with marshmallow.

Likelihood Probable Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, marshmallow flower might have antiplatelet effects.
Animal research suggests that marshmallow flower extract has antiplatelet effects. However, the root and leaf of marshmallow, not the flower, are the plant parts most commonly found in dietary supplements. Theoretically, use of marshmallow flower with anticoagulant/antiplatelet drugs can have additive effects, and might increase the risk for bleeding in some patients.

Likelihood Unlikely Evidence D
Oral Drugs

Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Marshmallow contains mucilage which can affect oral drug absorption. To avoid changes in absorption, take marshmallow 30-60 minutes after oral medications.

Likelihood Possible Evidence D
Marshmallow full monograph & interactions

Dietary Fiber7 drug types · 2,025 drugs

Carbamazepine (Tegretol)

Theoretically, black psyllium might reduce the effects of carbamazepine and increase the risk for convulsions.
Theoretically, black psyllium might reduce carbamazepine absorption. A preliminary study using blond psyllium reported decreased carbamazepine bioavailability due to binding of the drug to psyllium, as well as reduction of available fluid in the gut for dissolution of the drug. This interaction may also occur with black psyllium.

Likelihood Probable Evidence D
Lithium

Theoretically, taking black psyllium at the same time as lithium might reduce lithium absorption.
The fiber in black psyllium might reduce lithium absorption and plasma levels. Some case reports describe a reduction in plasma lithium levels with concomitant administration of blond psyllium. This was reversed when psyllium was stopped. This interaction may also occur with black psyllium.

Likelihood Probable Evidence D
Metformin (Glucophage)

Theoretically, black psyllium might increase the therapeutic and adverse effects of metformin.
Animal research shows that concurrent consumption of blond psyllium with metformin slows and increases the absorption of metformin. This interaction may also occur with black psyllium. To avoid changes in absorption, take psyllium 30-60 minutes after metformin.

Likelihood Possible Evidence D
Olanzapine (Zyprexa)

Theoretically, taking black psyllium at the same time as olanzapine might reduce olanzapine absorption.
The fiber in black psyllium might decrease the absorption of olanzapine. A single case report describes a reduction in the effectiveness of olanzapine when it was concomitantly administered with an unspecified type of psyllium 3 grams orally twice daily. This effect was reversed when psyllium was stopped.

Likelihood Possible Evidence D
Digoxin (Lanoxin)

Theoretically, taking black psyllium at the same time as digoxin might reduce digoxin absorption and decrease digoxin levels.
Psyllium might bind digoxin in the gut. However, some clinical evidence suggests that psyllium does not impact digoxin absorption.

Likelihood Unlikely Evidence B
Ethinyl Estradiol

Theoretically, taking black psyllium at the same time as ethinyl estradiol might alter levels of estradiol.
Concurrent use of blond psyllium with ethinyl estradiol results in a slight increase in the extent of ethinyl estradiol absorption and a slower rate of absorption. This is unlikely to be clinically significant.

Likelihood Unlikely Evidence D
Oral Drugs

Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Psyllium seems to have variable effects on drug absorption. To avoid changes in absorption, take psyllium 30-60 minutes after oral medications. Animal research shows that blond psyllium delays and increases the absorption of metformin and ethinyl estradiol. Case reports and animal research suggest that blond psyllium might reduce absorption of lithium, digoxin, olanzapine, and carbamazepine. Finally, some pharmacokinetic studies show that psyllium does not affect the absorption of levothyroxine or warfarin. Although many of these studies evaluated blond psyllium, the fiber content in black psyllium may have similar effects.

Likelihood Possible Evidence B
Dietary Fiber full monograph & interactions

Guar Gum5 drug types · 2,025 drugs

Ethinyl Estradiol

Theoretically, guar gum might reduce the absorption of ethinyl estradiol, potentially decreasing its effectiveness.
Animal research shows that taking guar gum with ethinyl estradiol decreases ethinyl estradiol absorption. However, this effect has not been reported in humans.

Likelihood Possible Evidence D
Metformin (Glucophage)

Guar gum might reduce the absorption of metformin, potentially decreasing its effectiveness.
A small study in healthy volunteers shows that guar gum reduces the absorption rate of metformin.

Likelihood Probable Evidence B
Oral Drugs

Guar gum might reduce the absorption of some oral drugs, potentially decreasing their effectiveness.
Clinical research shows that guar gum reduces or slows absorption of medications such as penicillin and metformin. To avoid changes in absorption, take guar gum 30-60 minutes after oral medications.

Likelihood Possible Evidence B
Penicillin

Guar gum might reduce the absorption of penicillin, potentially decreasing its effectiveness.
A small clinical study in healthy volunteers shows that taking guar gum with penicillin results in decreased penicillin absorption and reduced penicillin levels.

Likelihood Probable Evidence B
Digoxin (Lanoxin)

Guar gum might slow digoxin absorption, but it does not seem to impact how much digoxin is absorbed overall.
Two small studies in healthy volunteers show no change in the overall extent of digoxin absorption, although early absorption was slowed, when taken with guar gum.

Likelihood Possible Evidence B
Guar Gum full monograph & interactions

Slippery Elm1 drug type · 2,022 drugs

Oral Drugs

Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Slippery elm inner bark contains mucilage, which may interfere with the absorption of orally administered drugs.

Likelihood Possible Evidence D
Slippery Elm full monograph & interactions

Fennel6 drug types · 740 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, fennel might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.

Animal research suggests that fennel oil has antithrombotic and antiplatelet effects.

Likelihood Possible Evidence D
Ciprofloxacin (Cipro)

Theoretically, fennel might decrease the levels and clinical effects of ciprofloxacin.

Animal research shows that fennel reduces ciprofloxacin bioavailability by nearly 50%, possibly due to the metal cations such as calcium, iron, and magnesium contained in fennel. This study also found that fennel increased tissue distribution and slowed elimination of ciprofloxacin.

Likelihood Probable Evidence D
Contraceptive Drugs

Theoretically, taking large amounts of fennel might decrease the effects of contraceptive drugs due to competition for estrogen receptors.

Some constituents of fennel have estrogenic activity.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.

In vitro research suggests that fennel inhibits CYP3A4 enzyme activity. This effect has not been reported in humans.

Likelihood Possible Evidence D
Estrogens

Theoretically, taking large amounts of fennel might interfere with hormone replacement therapy due to competition for estrogen receptors.

Some constituents of fennel have estrogenic activity.

Likelihood Possible Evidence D
Tamoxifen (Nolvadex)

Theoretically, taking large amounts of fennel might decrease the antiestrogenic effect of tamoxifen.

Some constituents of fennel have estrogenic activity, which may interfere with the antiestrogenic activity of tamoxifen.

Likelihood Possible Evidence D
Fennel full monograph & interactions

Probiotic Blend1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L. acidophilus.
L. acidophilus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. acidophilus preparations by at least two hours.

Likelihood Probable Evidence D
Probiotic Blend full monograph & interactions

L-Glutamine1 drug type · 50 drugs

Anticonvulsants

Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Glutamine is metabolized to the excitatory neurotransmitter glutamate. Glutamate might have antagonistic effects with anticonvulsant drugs. However, this interaction has not yet been reported in humans.

Likelihood Possible Evidence D
L-Glutamine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for FiberMax Caps, from the product label.

Advanced Naturals

See all Advanced Naturals products
Name
Advanced Naturals
City
Palm Harbor
State
FL
ZipCode
34683
Phone Number
1-800-690-9988
Web Address
www.advancednaturals.com
Pharmacist Counseling Corner

FiberMax Caps by Advanced Naturals: Common Questions

Does FiberMax Caps by Advanced Naturals interact with any medications?
Yes. Based on its ingredients, FiberMax Caps has a known interaction with 2,153 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
FiberMax Caps contains 11 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take FiberMax Caps if I'm on birth control?
Fennel in this product may reduce the effectiveness of hormonal birth control by competing for estrogen receptors. Talk with your pharmacist or doctor before adding this supplement to your routine — you may need a different form of contraception or to avoid this product.
Is it safe to take with antibiotics?
No. The live probiotic bacteria in FiberMax Caps can be killed by antibiotics, which defeats the purpose of taking them. Space your antibiotic dose at least 2 hours away from this supplement — preferably take antibiotics first, then FiberMax Caps later.
Will this help with my constipation?
Possibly. Guar gum in the product is rated possibly effective for constipation, and the fiber sources are designed to support bowel regularity. However, the effectiveness ratings for slippery elm and marshmallow are insufficient — the evidence doesn't establish whether they help. Start with a small dose and drink plenty of water to avoid bloating or cramping.
Is it safe during pregnancy?
L-glutamine is likely safe, and B. bifidum and L. acidophilus are possibly safe in pregnancy. However, fennel is rated possibly unsafe, marshmallow is possibly unsafe, and guar gum has not been well studied in pregnancy. Talk with your doctor or midwife before starting any new supplement during pregnancy.
What are the most common side effects?
Bloating, gas, diarrhea, and constipation are typical, especially when you first start. L-glutamine at higher doses may also cause nausea or vomiting. These effects often improve as your body adjusts — starting with a smaller dose and gradually increasing can help.
Can I take this with metformin or other diabetes medications?
Guar gum in this product may reduce how well metformin is absorbed. Take your metformin at least 30–60 minutes before or after taking FiberMax Caps. Check with your pharmacist about your specific diabetes medication, as fennel also has other drug interactions.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

FiberMax Caps label
Go deeper

The Full Monographs Behind FiberMax Caps’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Black Psyllium

Interacts with 2,025 drugs

Black psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. It is best known and most studied for rel...

Read the full Black Psyllium monograph → Herb & supplement monograph

Glutamine

Interacts with 50 drugs

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle cell disease complications, but for most...

Read the full Glutamine monograph → Herb & supplement monograph

Slippery Elm

Interacts with 2,022 drugs

Slippery elm is a traditional herbal remedy made from the inner bark of a North American elm tree, used mainly to soothe sore throats and irritated digestive tracts. Its mucilage can coat an...

Read the full Slippery Elm monograph → Herb & supplement monograph

Marshmallow

Interacts with 2,040 drugs

Marshmallow root is a traditional herb rich in soothing, gel-like fibers called mucilage, which is why it has long been used for coughs, sore throats, and stomach irritation. Evidence for th...

Read the full Marshmallow monograph → Herb & supplement monograph

Fennel

Interacts with 740 drugs

Fennel is a Mediterranean herb widely used as a food and spice, and traditionally taken for digestive complaints, colic, and menstrual cramps. Some small studies suggest possible benefit for...

Read the full Fennel monograph → Herb & supplement monograph

Lactobacillus Acidophilus

Interacts with 182 drugs

Lactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy people, and there is reasonable evidence...

Read the full Lactobacillus Acidophilus monograph → Herb & supplement monograph

Guar Gum

Interacts with 2,025 drugs

Guar gum is a soluble, gel-forming fiber from the guar bean that may modestly help with cholesterol, blood sugar, and bowel regularity. It is generally safe in food amounts, but concentrated...

Read the full Guar Gum monograph →
Sources

Sources & How We Checked

FiberMax Caps's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 102 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Glutamine 11 references
  1. Miller AL. Therapeutic considerations of L-glutamine: a review of the literature. Altern Med Rev 1999;4:239-48..
  2. Bozzetti F, Biganzoli L, Gavazzi C, et al. Glutamine supplementation in cancer patients receiving chemotherapy: a double-blind randomized study. Nutrition 1997;13:748-51.. PubMed
  3. Mebane AH. L-Glutamine and mania. Am J Psychiatry 984;141:1302-3.
  4. Meldrum BS. Glutamate as a neurotransmitter in the brain: review of physiology and pathology. J Nutr 2000;130:1007S-15S.. PubMed
  5. Garlick PJ. Assessment of the safety of glutamine and other amino acids. J Nutr 2001;131:2556S-61S.. PubMed
  6. Chapman AG. Glutamate and epilepsy. J Nutr 2000;130:1043S-5S.. PubMed
  7. Ziegler TR. Glutamine supplementation in cancer patients receiving bone marrow transplantation and high dose chemotherapy. J Nutr 2001;131:2578S-84S.. PubMed
  8. Laviano A, Molfino A, Lacaria MT, Canelli A, De Leo S, Preziosa I, Rossi Fanelli F. Glutamine supplementation favors weight loss in nondieting obese female patients. A pilot study. Eur J Clin Nutr. 2014 Nov;68(11):1264-6. PubMed
  9. Endari (l-glutamine) [package insert]. Torrance, CA: Emmaus Medical,Inc; 2017.
  10. Niihara Y, Miller ST, Kanter J, et al. A Phase 3 Trial of l-Glutamine in Sickle Cell Disease. N Engl J Med 2018;379(3):226-35. doi: 10.1056/NEJMoa1715971.
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Black Psyllium 18 references
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Slippery Elm 3 references
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Marshmallow 5 references
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Bifidobacterium Bifidum 7 references
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Fennel 17 references
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Lactobacillus Acidophilus 15 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
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  5. Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
  6. Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
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  9. Xiao SD, Zhang DZ, Lu H, et al. Multicenter, randomized, controlled trial of heat-killed Lactobacillus acidophilus LB in patients with chronic diarrhea. Adv Ther. 2003;20(5):253-60.
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  13. Stoffer JN, Slingsby TJ, Giuliari GP. Lactobacillus acidophilus endophthalmitis after intravitreal bevacizumab injection requiring intraocular lens explantation. Can J Ophthalmol 2022;57(1):e21-e22. PubMed
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Guar Gum 26 references
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  14. Patrick PG, Gohman SM, Marx SC, et al. Effect of supplements of partially hydrolyzed guar gum on the occurrence of constipation and use of laxative agents. J Am Diet Assoc 1998;98:912-4. PubMed
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  17. Riikonen, S., Savonius, H., Gylling, H., Nikkila, K., Tuomi, A. M., and Miettinen, T. A. Oral guar gum, a gel-forming dietary fiber relieves pruritus in intrahepatic cholestasis of pregnancy. Acta Obstet.Gynecol.Scand. 2000;79(4):260-264. DOI
  18. Kovacs, E. M., Westerterp-Plantenga, M. S., Saris, W. H., Goossens, I., Geurten, P., and Brouns, F. The effect of addition of modified guar gum to a low-energy semisolid meal on appetite and body weight loss. Int.J.Obes.Relat Metab Disord. 2001;25(3):307 PubMed
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  21. Cicero, A. F., Derosa, G., Manca, M., Bove, M., Borghi, C., and Gaddi, A. V. Different effect of psyllium and guar dietary supplementation on blood pressure control in hypertensive overweight patients: a six-month, randomized clinical trial. Clin.Exp.Hyp PubMed
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  23. Salenius JP, Harju E, Jokela H, et al. Long term effects of guar gum on lipid metabolism after carotid endarterectomy. BMJ 1-14-1995;310:95-96. PubMed
  24. Gylling, H., Riikonen, S., Nikkila, K., Savonius, H., and Miettinen, T. A. Oral guar gum treatment of intrahepatic cholestasis and pruritus in pregnant women: effects on serum cholestanol and other non-cholesterol sterols. Eur.J.Clin.Invest 1998;28(5):35 PubMed
  25. Brillantino A, Iacobellis F, Izzo G, et al. Maintenance therapy with partially hydrolyzed guar gum in the conservative treatment of chronic anal fissure: results of a prospective, randomized study. Biomed Res Int 2014;2014:964942. PubMed
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See these in context on the Guar Gum monograph →

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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