Fish Oil +Resveratrol Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Fish Oil +Resveratrol against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Fish Oil +Resveratrol is a dietary supplement by GNC Triple Strength with 3 active ingredients. Its ingredients are commonly taken for heart and blood vessel health, antioxidant support, anti-aging.Based on those ingredients, 822 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Resveratrol. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Fish Oil +Resveratrol by GNC Triple Strength
Ask about any prescription or over-the-counter medication and we check it for interactions with Fish Oil +Resveratrol by GNC Triple Strength — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Fish Oil +Resveratrol by GNC Triple Strength
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains 3 active ingredients: two omega-3 fatty acids from fish oil (eicosapentaenoic acid and docosahexaenoic acid) and resveratrol, a plant compound. The inactive ingredients are fish body oil, gelatin, glycerin, an enteric coating (which helps the capsule dissolve in your intestines rather than your stomach), titanium dioxide, soy lecithin, and riboflavin.
Does it work?
Not established
Resveratrol shows possibly effective evidence for obesity and allergic rhinitis (hay fever). For cardiovascular disease and high cholesterol, the evidence currently leans toward possibly ineffective.
The fish oil ingredients themselves have no effectiveness ratings in our data, so we can't speak to what they may or may not do in this formulation.
How safe is it?
Well-documented data
Resveratrol is generally well tolerated at typical supplement doses. At higher doses, some people report diarrhea, loose stools, and general digestive upset.
A small number of trial participants and case reports have noted headache, fatigue, memory loss, or skin rashes, though in most cases these went away once the supplement was stopped. The safety data advises against this concentrated supplement during pregnancy and breastfeeding — there isn't enough information to know whether it's safe for you or your baby at those times.
Meds to double-check
Moderate interaction found
Double-check this product if you take blood thinners or antiplatelet medications like warfarin, aspirin, or clopidogrel — resveratrol may add to the bleeding risk. Also check if you take drugs metabolized by liver enzymes CYP2C19, CYP1A2, CYP2E1, or CYP3A4, since resveratrol may raise their levels.
The bottom line
Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.
If you take blood thinners, antiplatelet drugs, or medications your liver processes through CYP enzymes, you'll want to check this product with your pharmacist or doctor first. Otherwise, for general use, resveratrol is generally well tolerated, though some people get digestive upset at higher doses.
Talk to your pharmacist about your own medications before starting.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 26, 2011.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Fish Oil +Resveratrol, straight from the product label.
| Brand | GNC Triple Strength |
|---|---|
| Net contents | 60 Softgel(s) |
| Market status | On market |
| Date entered into DSLD | Oct 26, 2011 |
| DSLD ID | 1071 |
| Product type | Other Combinations |
| Supplement form | Softgel Capsule |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Fish Oil +Resveratrol by GNC Triple Strength, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Calories | 15 {Calories} | -- |
| Calories from Fat | 15 {Calories} | -- |
| Total Fat | 1.5 g | 2% |
| Eicosapentaenoic Acid | 647 mg | -- |
| Docosahexaenoic Acid | 253 mg | -- |
| Resveratrol | 125 mg | -- |
Other ingredients: Fish Body Oil, Gelatin, Glycerin, Enteric Coating, Titanium Dioxide, Soy Lecithin, Riboflavin
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Disclaimer Statement
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
FDA Statement of Identity
DIETARY SUPPLEMENT
Formula
• 900 mg of total omega-3 fatty acids and 125 mg of trans-resveratrol • Breakthrough antioxidant protection to fight cell-aging* • Provides heart, brain, joint, eye and skin heaIth*
Formulation
No Sugar, No Starch, No Artificial Colors, No Artificial Flavors, No Preservatives, No Wheat, No Gluten, No Corn, No Dairy, Yeast Free.
Precautions
KEEP OUT OF REACH OF CHILDREN.
WARNING: Consult your physician prior to using this product if you are pregnant, nursing, taking medication, or have a medical condition. Discontinue use two weeks prior to surgery.
Storage
Store in a cool, dry place.
General Statements
ACTUAL SIZE
Conforms to USP <2091> for weight.
Enteric Coated
GNC GUARANTEE Use any GNC supplement for as little as 10 days. If you are not 100% completely satisfied, return the unused portion of the product with proof of purchase to your GNC store for a complete refund of your purchase price. No questions asked!
GNC QUALITY COMMITMENT GNC, the leader in the development and manufacture of dietary supplements, is committed to producing the highest quality products available. This commitment begins with quality designed supplement formulations. Every raw material that goes into a GNC supplement is guaranteed as to quality and potency. Each product is dated and then shipped immediately to our stores, so you can be sure you are purchasing the freshest supplements available. At GNC, we extend our quality commitment to you by offering our money-back guarantee.
GNC Triple Strength Fish Oil plus Resveratrol combines a total of 900 mg of heart-healthy omega-3 fatty acids, EPA and DHA, with 125 mg of trans-resveratrol the potent cell protector and polyphenol found in the skin of red grapes and in some plants and berries. This formula has been enteric coated to control or reduce fishy burps by allowing the softgel capsule to break down and absorb in the small intestine. GNC Triple Strength Fish Oil plus Resveratrol offers many health benefits: The omega-3 fatty acids found in fish oil: • Are necessary for heart health and help support healthy joints* • Support normal, healthy cholesterol levels and are necessary in the maintenance of normal blood pressure* • Support skin heaIth* Resveratrol: • Helps protect against free radicals that can destroy healthy cells, damage tissue and promote the celI-aging process* GNC Triple Strength Fish Oil plus Resveratrol has been purified and manufactured for freshness and found to be free of detectable levels of mercury, cadmium, lead and PCBs. We use only the best quality ingredients derived from wild, deep ocean fish.
Please recycle this box.
Potency verified by GNC procedureS #5123 & #5297.
General
CODE 883411 AMG
Suggested/Recommended/Usage/Directions
Directions: As a dietary supplement, take one softgel capsule daily with food.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Fish Oil +Resveratrol by GNC Triple Strength label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Fish Oil +Resveratrol by GNC Triple Strength
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Softgel(s) Dosage formSoftgel Capsule Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Eicosapentaenoic Acid
Docosahexaenoic Acid
Resveratrol
Interacts with822 drugs
Resveratrol is a plant compound found in red grapes, berries, and peanuts that is popular for heart health, anti-aging, and antioxidant support. While...
Resveratrol monograph & interactionsOther (inactive) ingredients: Fish Body Oil, Gelatin, Glycerin, Enteric Coating, Titanium Dioxide, Soy Lecithin, Riboflavin. These complete the product’s ingredient list but are not active constituents.
Fish Oil +Resveratrol by GNC Triple Strength Drug Interactions
HelloPharmacist Interaction Report
GNC Triple Strength Fish Oil + Resveratrol has documented interactions with several medication types, all involving the resveratrol ingredient.
The most serious concern is with blood thinners and antiplatelet drugs (like warfarin, aspirin, and clopidogrel): resveratrol may have mild blood-thinning effects of its own and could increase your bleeding risk if you're already on these medications.
Read the full breakdown — every affected drug type, severity by severity
Resveratrol may also affect how your body processes drugs metabolized by three liver enzymes — CYP2C19, CYP1A2, and CYP2E1 — potentially raising levels of those medications. A fourth group, drugs broken down by CYP3A4, showed theoretical risk in the lab, though a clinical study at high doses (3000 mg daily) found no dose adjustments were needed.
All four enzyme-related interactions are rated Moderate severity. We could not check the two fish oil ingredients (eicosapentaenoic acid and docosahexaenoic acid) — we hold no interaction data for them.
Altogether, these interactions span 812 individual medications. If you take any prescription medication — especially blood thinners, antiplatelet drugs, or anything your doctor says your liver metabolizes — run it through the checker below before you start this product.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Fish Oil +Resveratrol?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Fish Oil +Resveratrol interact with 822 drugs. Click any drug to see the details.
1 of the 3 ingredients in Fish Oil +Resveratrol interact with drugs. Each result below shows which ingredient is responsible. Resveratrol
Ado-trastuzumab EmtansineKadcyla
How Ado-trastuzumab Emtansine interacts with Fish Oil +Resveratrol — through 1 ingredient. Tap an ingredient for the detail:
ResveratrolCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, resveratrol might increase levels of drugs metabolized by CYP3A4.
Read the full Resveratrol + Ado-trastuzumab Emtansine interactionAbciximabReoPro
How Abciximab interacts with Fish Oil +Resveratrol — through 1 ingredient. Tap an ingredient for the detail:
ResveratrolAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Resveratrol may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Resveratrol + Abciximab interactionAbemaciclibVerzenio
How Abemaciclib interacts with Fish Oil +Resveratrol — through 1 ingredient. Tap an ingredient for the detail:
ResveratrolCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, resveratrol might increase levels of drugs metabolized by CYP3A4.
Read the full Resveratrol + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Fish Oil +Resveratrol — through 1 ingredient. Tap an ingredient for the detail:
ResveratrolCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, resveratrol might increase levels of drugs metabolized by CYP3A4.
Read the full Resveratrol + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Fish Oil +Resveratrol — through 1 ingredient. Tap an ingredient for the detail:
ResveratrolCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, resveratrol might increase levels of drugs metabolized by CYP3A4.
Read the full Resveratrol + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Fish Oil +Resveratrol — through 1 ingredient. Tap an ingredient for the detail:
ResveratrolAnticoagulant/antiplatelet Drugs, Cytochrome P450 2c19 (cyp2c19) Substrates Moderate
Interaction Summary
Resveratrol may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Resveratrol + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Fish Oil +Resveratrol — through 1 ingredient. Tap an ingredient for the detail:
ResveratrolCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, resveratrol might increase levels of drugs metabolized by CYP3A4.
Read the full Resveratrol + Acalabrutinib interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Fish Oil +Resveratrol — through 1 ingredient. Tap an ingredient for the detail:
ResveratrolAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Resveratrol may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Resveratrol + Acenocoumarol interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Fish Oil +Resveratrol — through 1 ingredient. Tap an ingredient for the detail:
ResveratrolCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Resveratrol might increase levels of drugs metabolized by CYP2E1.
Read the full Resveratrol + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Fish Oil +Resveratrol — through 1 ingredient. Tap an ingredient for the detail:
ResveratrolCytochrome P450 1a2 (cyp1a2) Substrates, Anticoagulant/antiplatelet Drugs +1 Moderate
Interaction Summary
Theoretically, resveratrol might increase levels of drugs metabolized by CYP1A2.
Read the full Resveratrol + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Fish Oil +Resveratrol — through 1 ingredient. Tap an ingredient for the detail:
ResveratrolCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +2 Moderate
Interaction Summary
Resveratrol might increase levels of drugs metabolized by CYP2E1.
Read the full Resveratrol + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Fish Oil +Resveratrol — through 1 ingredient. Tap an ingredient for the detail:
ResveratrolCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Resveratrol might increase levels of drugs metabolized by CYP2E1.
Read the full Resveratrol + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Fish Oil +Resveratrol — through 1 ingredient. Tap an ingredient for the detail:
ResveratrolCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, resveratrol might increase levels of drugs metabolized by CYP1A2.
Read the full Resveratrol + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Fish Oil +Resveratrol — through 1 ingredient. Tap an ingredient for the detail:
ResveratrolCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Resveratrol might increase levels of drugs metabolized by CYP2E1.
Read the full Resveratrol + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Fish Oil +Resveratrol — through 1 ingredient. Tap an ingredient for the detail:
ResveratrolCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, resveratrol might increase levels of drugs metabolized by CYP3A4.
Read the full Resveratrol + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Fish Oil +Resveratrol — through 1 ingredient. Tap an ingredient for the detail:
ResveratrolCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Resveratrol might increase levels of drugs metabolized by CYP2E1.
Read the full Resveratrol + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Fish Oil +Resveratrol — through 1 ingredient. Tap an ingredient for the detail:
ResveratrolCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, resveratrol might increase levels of drugs metabolized by CYP1A2.
Read the full Resveratrol + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Fish Oil +Resveratrol — through 1 ingredient. Tap an ingredient for the detail:
ResveratrolCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Resveratrol might increase levels of drugs metabolized by CYP2E1.
Read the full Resveratrol + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Fish Oil +Resveratrol — through 1 ingredient. Tap an ingredient for the detail:
ResveratrolCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, resveratrol might increase levels of drugs metabolized by CYP3A4.
Read the full Resveratrol + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Fish Oil +Resveratrol — through 1 ingredient. Tap an ingredient for the detail:
ResveratrolCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Resveratrol might increase levels of drugs metabolized by CYP2E1.
Read the full Resveratrol + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Fish Oil +Resveratrol — through 1 ingredient. Tap an ingredient for the detail:
ResveratrolCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, resveratrol might increase levels of drugs metabolized by CYP3A4.
Read the full Resveratrol + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Fish Oil +Resveratrol — through 1 ingredient. Tap an ingredient for the detail:
ResveratrolCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Resveratrol might increase levels of drugs metabolized by CYP2E1.
Read the full Resveratrol + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Fish Oil +Resveratrol — through 1 ingredient. Tap an ingredient for the detail:
ResveratrolCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, resveratrol might increase levels of drugs metabolized by CYP3A4.
Read the full Resveratrol + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Fish Oil +Resveratrol — through 1 ingredient. Tap an ingredient for the detail:
ResveratrolCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Resveratrol might increase levels of drugs metabolized by CYP2E1.
Read the full Resveratrol + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Fish Oil +Resveratrol — through 1 ingredient. Tap an ingredient for the detail:
ResveratrolCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Resveratrol might increase levels of drugs metabolized by CYP2E1.
Read the full Resveratrol + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Fish Oil +Resveratrol — through 1 ingredient. Tap an ingredient for the detail:
ResveratrolCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2e1 (cyp2e1) Substrates +1 Moderate
Interaction Summary
Theoretically, resveratrol might increase levels of drugs metabolized by CYP1A2.
Read the full Resveratrol + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Fish Oil +Resveratrol — through 1 ingredient. Tap an ingredient for the detail:
ResveratrolCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2e1 (cyp2e1) Substrates +1 Moderate
Interaction Summary
Theoretically, resveratrol might increase levels of drugs metabolized by CYP3A4.
Read the full Resveratrol + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Fish Oil +Resveratrol — through 1 ingredient. Tap an ingredient for the detail:
ResveratrolCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2e1 (cyp2e1) Substrates +1 Moderate
Interaction Summary
Theoretically, resveratrol might increase levels of drugs metabolized by CYP1A2.
Read the full Resveratrol + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with Fish Oil +Resveratrol — through 1 ingredient. Tap an ingredient for the detail:
ResveratrolCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, resveratrol might increase levels of drugs metabolized by CYP3A4.
Read the full Resveratrol + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, SalicylamideRhinogesic GG
How Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interacts with Fish Oil +Resveratrol — through 1 ingredient. Tap an ingredient for the detail:
ResveratrolCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Resveratrol might increase levels of drugs metabolized by CYP2E1.
Read the full Resveratrol + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Fish Oil +Resveratrol with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Resveratrol
Anticoagulant/Antiplatelet Drugs
Resveratrol may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Resveratrol seems to have antiplatelet effects.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, resveratrol might increase levels of drugs metabolized by CYP1A2.
In vitro research shows that resveratrol can inhibit CYP1A2 enzymes. However, this interaction has not been reported in humans.
Cytochrome P450 2C19 (Cyp2C19) Substrates
Theoretically, resveratrol might increase levels of drugs metabolized by CYP2C19.
In vitro research shows that resveratrol can inhibit CYP2C19 enzymes. However, this interaction has not been reported in humans.
Cytochrome P450 2E1 (Cyp2E1) Substrates
Resveratrol might increase levels of drugs metabolized by CYP2E1.
In vitro research suggests that resveratrol inhibits CYP2E1 isoenzyme. Also, a pharmacokinetic study shows that taking resveratrol 500 mg daily for 10 days prior to taking a single dose of chlorzoxazone 250 mg increases the maximum concentration of chlorzoxazone by about 54%, the area under the curve of chlorzoxazone by about 72%, and the half-life of chlorzoxazone by about 35%. Chlorzoxazone is used as a probe drug for CYP2E1.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, resveratrol might increase levels of drugs metabolized by CYP3A4.
In vitro research shows that resveratrol can inhibit the CYP3A4 enzyme. However, clinical research shows that taking resveratrol 3000 mg daily for 8 weeks does not necessitate dose adjustments to medications metabolized by CYP3A4.
Brand information
Manufacturer and brand details for Fish Oil +Resveratrol, from the product label.
Fish Oil +Resveratrol by GNC Triple Strength: Common Questions
Does Fish Oil +Resveratrol by GNC Triple Strength interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Will this help me lose weight?
Can I take this if I'm pregnant or breastfeeding?
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The Full Monographs Behind Fish Oil +Resveratrol’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Fish Oil +Resveratrol's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 24 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Resveratrol 24 references
- Soleas GJ, Diamandis EP, Goldberg DM. Resveratrol: a molecule whose time has come? And gone? Clin Biochem 1997;30:91-113.
- Pace-Asciak CR, Rounova O, Hahn SE, et al. Wines and grape juices as modulators of platelet aggregation in healthy human subjects. Clin Chim Acta 1996;246:163-82. PubMed
- Bertelli AA, Giovannini L, Bernini W, et al. Antiplatelet activity of cis-resveratrol. Drugs Exp Clin Res 1996;22:61-3.
- Pace-Asciak CR, Hahn S, Diamandis EP, et al. The red wine phenolics trans-resveratrol and quercetin block human platelet aggregation and eicosanoid synthesis: implications for protection against coronary heart disease. Clin Chim Acta 1995;235:207-19.
- Bertelli A, Bertelli AA, Gozzini A, Giovannini L. Plasma and tissue resveratrol concentrations and pharmacological activity. Drugs Exp Clin Res 1998;24:133-8.
- Bertelli AA, Giovannini L, Giannessi D, et al. Antiplatelet activity of synthetic and natural resveratrol in red wine. Int J Tissue React 1995;17:1-3.
- Piver B, Berthou F, Dreano Y, Lucas D. Inhibition of CYP3A, CYP1A and CYP2E1 activities by resveratrol and other non volatile red wine components. Toxicol Lett 2001;125:83-91. PubMed
- Chang, T. K., Chen, J., and Lee, W. B. Differential inhibition and inactivation of human CYP1 enzymes by trans-resveratrol: evidence for mechanism-based inactivation of CYP1A2. J.Pharmacol.Exp.Ther. 2001;299(3):874-882.
- Dobrydneva, Y., Williams, R. L., and Blackmore, P. F. trans-Resveratrol inhibits calcium influx in thrombin-stimulated human platelets. Br.J.Pharmacol. 1999;128(1):149-157.
- Kirk, R. I., Deitch, J. A., Wu, J. M., and Lerea, K. M. Resveratrol decreases early signaling events in washed platelets but has little effect on platalet in whole food. Blood Cells Mol.Dis. 2000;26(2):144-150.
- Zbikowska, H. M. and Olas, B. Antioxidants with carcinostatic activity (resveratrol, vitamin E and selenium) in modulation of blood platelet adhesion. J Physiol Pharmacol. 2000;51(3):513-520.
- Olas, B., Wachowicz, B., Saluk-Juszczak, J., and Zielinski, T. Effect of resveratrol, a natural polyphenolic compound, on platelet activation induced by endotoxin or thrombin. Thromb.Res 8-15-2002;107(3-4):141-145. PubMed
- Yu, C., Shin, Y. G., Kosmeder, J. W., Pezzuto, J. M., and van Breemen, R. B. Liquid chromatography/tandem mass spectrometric determination of inhibition of human cytochrome P450 isozymes by resveratrol and resveratrol-3-sulfate. Rapid Commun.Mass Spectro PubMed
- Ma, Z. H. and Ma, Q. Y. Resveratrol: a medical drug for acute pancreatitis. World J Gastroenterol. 6-7-2005;11(21):3171-3174. PubMed
- la, Porte C., Voduc, N., Zhang, G., Seguin, I., Tardiff, D., Singhal, N., and Cameron, D. W. Steady-State pharmacokinetics and tolerability of trans-resveratrol 2000 mg twice daily with food, quercetin and alcohol (ethanol) in healthy human subjects. Cli PubMed
- Brown, V. A., Patel, K. R., Viskaduraki, M., Crowell, J. A., Perloff, M., Booth, T. D., Vasilinin, G., Sen, A., Schinas, A. M., Piccirilli, G., Brown, K., Steward, W. P., Gescher, A. J., and Brenner, D. E. Repeat dose study of the cancer chemopreventive
- Pendurthi, U. R., Williams, J. T., and Rao, L. V. Resveratrol, a polyphenolic compound found in wine, inhibits tissue factor expression in vascular cells : A possible mechanism for the cardiovascular benefits associated with moderate consumption of wine. PubMed
- Chachay VS, Macdonald GA, Martin JH, Whitehead JP, O'Moore-Sullivan TM, Lee P, Franklin M, Klein K, Taylor PJ, Ferguson M, Coombes JS, Thomas GP, Cowin GJ, Kirkpatrick CM, Prins JB, Hickman IJ. Resveratrol does not benefit patients with nonalcoholic fatty
- Bedada SK, Neerati P. Resveratrol Pretreatment Affects CYP2E1 Activity of Chlorzoxazone in Healthy Human Volunteers. Phytother Res. 2016;30(3):463-8. PubMed
- Lin CT, Sun XY, Lin AX. Supplementation with high-dose trans-resveratrol improves ultrafiltration in peritoneal dialysis patients: a prospective, randomized, double-blind study. Ren Fail. 2016;38(2):214-21. PubMed
- Li Q, Yang G, Xu H, Tang S, Lee WY. Effects of resveratrol supplementation on bone quality: a systematic review and meta-analysis of randomized controlled trials. BMC Complement Med Ther 2021;21(1):214. PubMed
- McCreary MR, Schnell PM, Rhoda DA. Randomized double-blind placebo-controlled proof-of-concept trial of resveratrol for outpatient treatment of mild coronavirus disease (COVID-19). Sci Rep 2022;12(1):10978. PubMed
- Abdelhaleem IA, Brakat AM, Adayel HM, Asla MM, Rizk MA, Aboalfetoh AY. The effects of resveratrol on glycemic control and cardiometabolic parameters in patients with T2DM: A systematic review and meta-analysis. Med Clin (Barc) 2022;158(12):576-585. PubMed
- Badaoui A. Allergic contact dermatitis to resveratrol and Scutellaria baicalensis root extract in a cosmetic product. Contact Dermatitis 2022.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC