Interactions on record — worth a quick check against your medications. Based on 2 of 4 ingredients. Check your meds →
Dietary supplement

Krill Oil Mini Ingredients & Drug Interactions

by GNC Triple Strength

Krill Oil Mini label
See full label image
Softgel Capsule Category: Fat/fatty Acid
Most serious interaction: Minor
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Krill Oil Mini against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Minor

Krill Oil Mini is a dietary supplement by GNC Triple Strength with 4 active ingredients. Its ingredients are commonly taken for liver health and fatty liver, brain and memory support, prenatal nutrition and fetal development.Based on those ingredients, 16 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Choline. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Krill Oil Mini by GNC Triple Strength

Ask about any prescription or over-the-counter medication and we check it for interactions with Krill Oil Mini by GNC Triple Strength — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Krill Oil Mini by GNC Triple Strength

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 13, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 4 of its 4 active ingredients.
  • “Total Omega-3 Fatty Acids” is listed as a grouped ingredient — the label gives one combined amount (270 mg) without saying how much of each component you get.
  • “Total Phospholipids” is listed as a grouped ingredient — the label gives one combined amount (560 mg) without saying how much of each component you get.

GNC Triple Strength Krill Oil Mini is built around Antarctic krill—tiny shrimp-like creatures—which supply the omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). These are the key omega-3s that krill oil is known for.

The product also contains phosphatidylcholine (a type of fat that helps cells function) and choline (an essential nutrient related to brain and liver health), both naturally present in krill and added to support those roles. Beyond the 4 active ingredients, the softgel capsule includes krill oil, an enteric coating (which helps it survive stomach acid), and natural flavors.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: Supports heart, brain, and joint health.
  • We looked for evidence on: Cardiovascular disease (CVD), Atherosclerosis, Angina, Hypertension, Hyperlipidemia, Hyperlipoproteinemia — and 4 related terms.
  • The closest evidence on file: Choline is rated "Insufficient Reliable Evidence To Rate" for Age-related cognitive decline (Natural Medicines).
  • Also on file: Choline is rated "Insufficient Reliable Evidence To Rate" for Alzheimer disease, Cardiovascular disease (CVD), Hypertension, Metabolic syndrome.
  • Also on file: Phosphatidylcholine is rated "Insufficient Reliable Evidence To Rate" for Alzheimer disease, Angina.

The product contains phosphatidylcholine, which has possibly effective evidence for ulcerative colitis—a serious bowel condition. For other conditions like Alzheimer disease and anxiety, the evidence is insufficient to rate whether it works.

Choline (the nutrient in this formula) shows possibly ineffective evidence for athletic performance and insufficient evidence for Alzheimer disease, age-related cognitive decline, and other conditions we have data on. The omega-3s themselves (EPA and DHA)—the main reason most people buy krill oil—do not have effectiveness ratings in our data, so we cannot tell you whether they're established to work for any specific condition from what we hold.

The evidence, ingredient by ingredient Choline Phosphatidylcholine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Phosphatidylcholine is generally well tolerated when taken by mouth, though high doses may cause digestive upset—bloating, diarrhea, nausea, vomiting, altered taste, and itching have been reported. Choline is also well tolerated at food levels but can cause side effects at high doses (9 grams daily and above), including a fishy body odor, diarrhea, nausea, and vomiting.

The upper safe daily limit for choline is 3.5 grams; krill oil products are typically much lower. For pregnancy, choline is important and likely safe when used as directed, but prenatal decisions should be guided by your doctor.

Phosphatidylcholine supplement safety in pregnancy is not well studied beyond food sources. Breastfeeding needs for choline are higher, and any supplement use should be discussed with your healthcare provider first.

Side effects, ingredient by ingredient Choline Phosphatidylcholine

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — Choline.
  • The most serious interaction on file is rated Minor.
  • For scale: 16 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Minor interaction: Atropine—choline in this product may theoretically decrease its effects. Check your entire medication list before taking krill oil, especially any drugs for blood pressure, heart rhythm, blood clotting, cholesterol, or digestion; we have limited interaction data on the omega-3 fatty acids themselves, but 16 medications overall are flagged across this product's ingredients.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Only minor medication interactions are documented, and safety information is well characterized.

Krill Oil Mini delivers omega-3 fatty acids EPA and DHA plus phospholipid nutrients in a triple-strength dose. It's reasonable for someone looking to add omega-3s to their diet, but check your medications first—especially if you take atropine or any blood pressure, heart, or blood-thinning drug—with your own doctor or pharmacist before starting.

Pregnancy and breastfeeding use should be cleared with your healthcare provider.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 25, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Krill Oil Mini, straight from the product label.

Brand GNC Triple Strength
Barcode (UPC) 048107170509
Net contents 60 Mini Softgel(s)
Market status On market
Date entered into DSLD Feb 25, 2021
DSLD ID 243663
Product type Fat/fatty Acid
Supplement form Softgel Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Krill Oil Mini by GNC Triple Strength, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Mini Softgel(s)
Maximum serving Sizes:
2 Mini Softgel(s)
Servings per container
30
UPC/BARCODE
048107170509
IngredientAmount% DV
Calories10 Calorie(s)--
Eicosapentaenoic Acid150 mg--
Docosahexaenoic Acid70 mg--
Cholesterol30 mg10%
Total Fat1 Gram(s)1%
Total Omega-3 Fatty Acids270 mg--
Phosphatidyl Choline480 mg--
Choline70 mg13%
Total Phospholipids560 mg--

Other ingredients: Superba Boost Krill Oil, Capsule & Enteric Coating, Natural flavors

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

Keep out of reach of children.

Contains: Crustaceans (Krill).

Storage

Store in a cool, dry place.

Brand IP Statement(s)

Superba Boost is a trademark of the Aker Group.

Formula

220 mg of highly absorbable EPA/DHA Omega-3s

Formulation

Supports heart, brain, & joint health

No sugar, no starch, no artificial colors, no artificial flavors, no preservatives, sodium free, no wheat, gluten free, no corn, no soy, no diary, yeast free.

Enteric coated to help control fishy burps - guaranteed

Free of mercury, lead, heavy metals and PCBs.

FDA Statement of Identity

Omega-3 Supplement

Seals/Symbols

Certified Purified

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take two mini softgel capsules daily.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Krill Oil Mini by GNC Triple Strength label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Krill Oil Mini label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Krill Oil Mini by GNC Triple Strength

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Mini Softgel(s) Dosage formSoftgel Capsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Total Omega-3 Fatty Acids

270 mg per serving
  • › Eicosapentaenoic Acid
  • › Docosahexaenoic Acid

Choline

Interacts with
16 drugs
70 mg per serving

Choline is an essential nutrient your body needs for liver function, brain health, and nerve signaling, and many people get enough from foods like egg...

Choline monograph & interactions

Total Phospholipids

560 mg per serving

Other (inactive) ingredients: Superba Boost Krill Oil, Capsule & Enteric Coating, Natural flavors. These complete the product’s ingredient list but are not active constituents.

Interaction report

Krill Oil Mini by GNC Triple Strength Drug Interactions

Want to check YOUR meds against Krill Oil Mini?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
16Drugs
16 Minor

Ingredients driving the most interactions

Choline 16

Individual Drug Interactions

The ingredients in Krill Oil Mini interact with 16 drugs. Click any drug to see the details.

1 of the 4 ingredients in Krill Oil Mini interact with drugs. Each result below shows which ingredient is responsible. Choline

Each ingredient & the kinds of drugs it affects

For each ingredient in Krill Oil Mini with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Choline1 drug type · 16 drugs

Atropine

Theoretically, choline might decrease the effects of atropine in the brain.
Animal research shows that administering choline one hour before administering atropine can attenuate atropine-induced decreases in brain levels of acetylcholine. Theoretically, concomitant use of choline and atropine may decrease the effects of atropine.

Likelihood Possible Evidence D
Choline full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Krill Oil Mini, from the product label.

GNC Triple Strength

See all GNC Triple Strength products
Name
General Nutrition Corporation
City
Pittsburgh
State
PA
ZipCode
15222
Phone Number
1-888-462-2548
Web Address
gnc.com
Pharmacist Counseling Corner

Krill Oil Mini by GNC Triple Strength: Common Questions

Does Krill Oil Mini by GNC Triple Strength interact with any medications?
Yes. Based on its ingredients, Krill Oil Mini has a known interaction with 16 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Krill Oil Mini contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is krill oil safe while I'm pregnant?
Choline (in this product) is likely safe and important during pregnancy, but you should only use it as your doctor advises. Phosphatidylcholine safety beyond food sources isn't well studied in pregnancy, so talk with your doctor about whether this supplement is right for you.
Can I take this while breastfeeding?
Choline needs are higher while breastfeeding, but supplement use should be cleared with your healthcare provider first. We don't have enough reliable data on phosphatidylcholine for breastfeeding, so speak with your doctor before starting.
What side effects might I experience?
Most people tolerate krill oil well at typical doses. Phosphatidylcholine and choline can cause bloating, diarrhea, nausea, altered taste, or itching—though these are usually seen at higher doses. A fishy body odor is a known effect of choline supplements in some people.
Does this product actually work for anything?
Phosphatidylcholine is possibly effective for ulcerative colitis. The evidence for choline and other conditions in this product is either insufficient or not established. The omega-3s EPA and DHA are the main components people buy krill oil for, but we don't have effectiveness ratings on those in our data.
What's the difference between krill oil and regular fish oil?
Both contain EPA and DHA omega-3 fatty acids, but krill oil is extracted from Antarctic krill (small shrimp-like creatures) and naturally includes phospholipids like phosphatidylcholine. Fish oil comes from larger fish. The facts we hold don't compare their effectiveness directly.
Is there choline in here, and is it safe?
Yes—this product contains both phosphatidylcholine (a form of choline) and choline itself. Choline is well tolerated at food and normal supplement amounts, but very high doses (9 grams daily and above) can cause diarrhea, nausea, and a fishy body odor. The safe daily upper limit is 3.5 grams.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Krill Oil Mini label
Go deeper

The Full Monographs Behind Krill Oil Mini’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Choline

Interacts with 16 drugs

Choline is an essential nutrient your body needs for liver function, brain health, and nerve signaling, and many people get enough from foods like eggs, meat, and fish. Supplements may help...

Read the full Choline monograph → Herb & supplement monograph

Phosphatidylcholine

Phosphatidylcholine is a phospholipid that is part of every cell membrane and a source of choline. People take it for liver, brain, and gut health, but solid human evidence is limited for mo...

Read the full Phosphatidylcholine monograph →
Sources

Sources & How We Checked

Krill Oil Mini's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 29 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Phosphatidylcholine 15 references
  1. Domino EF, May WW, Demetriou S, et al. Lack of clinically significant improvement of patients with tardive dyskinesia following phosphatidylcholine therapy. Biol Psychiatry 1985;20:1189-96. PubMed
  2. Aronson PJ, Lorincz AL. Promotion of palmar sweating with oral phosphatidylcholine. Acta Derm Venereol 1985;65:19-24. DOI
  3. Hexsel DM, Serra M, de Oliveira Dal'Forno T, et al. Cosmetic uses of injectable phosphatidylcholine on the face. Otolaryngol Clin North Am 2005;38:1119-29. PubMed
  4. Kopera D, Binder B, Toplak H, et al. Histopathologic changes after intralesional application of phosphatidylcholine for lipoma reduction: report of a case. Am J Dermatopathol 2006;28:331-3. PubMed
  5. Rittes PG. The use of phosphatidylcholine for correction of lower lid bulging due to prominent fat pads. Dermatol Surg 2001;27:391-2. PubMed
  6. Rotunda AM, Kolodney MS. Mesotherapy and phosphatidylcholine injections: historical clarification and review. Dermatol Surg 2006;32:465-80. PubMed
  7. Hexsel D, Serra M, Mazzuco R, et al. Phosphatidylcholine in the treatment of localized fat. J Drugs Dermatol 2003;2:511-8.
  8. Hasengschwandtner F. Phosphatidylcholine treatment to induce lipolysis. Cosmet Dermatol 2005;4:308-13. PubMed
  9. Rittes PG. The use of phosphatidylcholine for correction of localized fat deposits. Aesthetic Plast Surg 2003;27:315-8. PubMed
  10. Ablon G, Rotunda AM. Treatment of lower eyelid fat pads using phosphatidylcholine: clinical trial and review. Dermatol Surg 2004;30:422-7. PubMed
  11. Loguercio C, Andreone P, Brisc C, et al. Silybin combined with phosphatidylcholine and vitamin E in patients with nonalcoholic fatty liver disease: a randomized controlled trial. Free Radic Biol Med 2012;52(9):1658-65. PubMed
  12. Panos, J. M., Palson, R., Johnson, R., Portmann, B., and Williams, R. Polyunsaturated phosphatidylcholine for acute alcoholic hepatitis: a double blind randomized placebo controlled trial. Eur.J.Gastroenterol 1990;2:351-355.
  13. Stremmel W, Braun A, Hanemann A, Ehehalt R, Autschbach F, Karner M. Delayed release phosphatidylcholine in chronic-active ulcerative colitis: a randomized, double-blinded, dose finding study. J Clin Gastroenterol 2010;44(5):e101-7. PubMed
  14. Stremmel W, Ehehalt R, Autschbach F, Karner M. Phosphatidylcholine for steroid-refractory chronic ulcerative colitis: a randomized trial. Ann Intern Med. 2007;147(9):603-10. PubMed
  15. Stremmel W, Vural H, Evliyaoglu O, Weiskirchen R. Delayed Release Phosphatidylcholine is Effective for Treatment of Ulcerative Colitis: A Meta-Analysis. Dig Dis 2021;39(5):508-515. PubMed

See these in context on the Phosphatidylcholine monograph →

Choline 14 references
  1. Yates AA, Schlicker SA, Suitor CW. Dietary reference intakes: The new basis for recommendations for calcium and related nutrients, B vitamins, and choline. J Am Diet Assoc 1998;98:699-706. PubMed
  2. Cho E, Willett WC, Colditz GA, et al. Dietary choline and betaine and the risk of distal colorectal adenoma in women. J Natl Cancer Inst 2007;99:1224-31. PubMed
  3. Schmidt, C., Abicht, A., Krampfl, K., Voss, W., Stucka, R., Mildner, G., Petrova, S., Schara, U., Mortier, W., Bufler, J., Huebner, A., and Lochmuller, H. Congenital myasthenic syndrome due to a novel missense mutation in the gene encoding choline acetyl
  4. Tamminga, C., Smith, R. C., Chang, S., Haraszti, J. S., and Davis, J. M. Depression associated with oral choline. Lancet 10-23-1976;2(7991):905. PubMed
  5. Wood, J. L. and Allison, R. G. Effects of consumption of choline and lecithin on neurological and cardiovascular systems. Fed.Proc. 1982;41(14):3015-3021.
  6. Growdon, J. H. and Gelenberg, A. J. Choline and lecithin administration to patients with tardive dyskinesia. Trans.Am.Neurol.Assoc. 1978;103:95-99.
  7. Smith, C. M., Swash, M., Exton-Smith, A. N., Phillips, M. J., Overstall, P. W., Piper, M. E., and Bailey, M. R. Choline therapy in Alzheimer's disease. Lancet 8-5-1978;2(8084):318. PubMed
  8. Morrison, L. M. and W. F. Gonzales. Choline in coronary atherosclerosis. Amer.Heart J. 1950;39:729.
  9. Christie, J. G. Blackburn 1. M. Glen A. I. M. Zeisel S. Shering A. & Yates C. M. Effects of choline and lecithin on CSF choline levels and on cognitive functioning in patients with presenile dementia of the Alzheimer type. Nutrition and the brain 1979;5
  10. Sidhu N, Davies S, Nadarajah A, et al. Oral choline supplementation for postoperative pain. Br J Anaesth 2013;111(2):249-55. PubMed
  11. Wozniak JR, Fuglestad AJ, Eckerle JK, et al. Choline supplementation in children with fetal alcohol spectrum disorders has high feasibility and tolerability. Nutr Res. 2013;33(11):897-904. PubMed
  12. Wozniak JR, Fuglestad AJ, Eckerle JK, et al. Choline supplementation in children with fetal alcohol disorders: a randomized, double-blind, placebo-controlled trial. Am J Clin Nutr. 2015;102(5): 1113-25.
  13. Ross RG, Hunter SK, McCarthy L, et al. Perinatal choline effects on neonatal pathophysiology related to later schizophrenia risk. Am J Psychiatry. 2013;170(3):290-8. PubMed
  14. Food and Nutrition Board, Institute of Medicine. Choline. Dietary Reference Intakes: Thiamin, Riboflavin, Niacin, Vitamin B-6, Vitamin B-12, Pantothenic Acid, Biotin, and Choline. Washington D.C.: National Academy Press; 1998:390-422.

See these in context on the Choline monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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