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Dietary supplement

For Attention With Phosphatidylserine Complex Ingredients & Drug Interactions

by Vita+Apps By V

For Attention With Phosphatidylserine Complex label
See full label image
Softgel Capsule Category: Fat/fatty Acid
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking For Attention With Phosphatidylserine Complex against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

For Attention With Phosphatidylserine Complex is a dietary supplement by Vita+Apps By V with 1 active ingredient. Its ingredients are commonly taken for memory and cognitive support, age-related cognitive decline, attention and focus (adhd).Based on those ingredients, 219 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Phosphatidylserine Complex. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against For Attention With Phosphatidylserine Complex by Vita+Apps By V

Ask about any prescription or over-the-counter medication and we check it for interactions with For Attention With Phosphatidylserine Complex by Vita+Apps By V — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of For Attention With Phosphatidylserine Complex by Vita+Apps By V

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 30, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 4 of its 4 active ingredients.
  • “Phosphatidylserine Complex” is a proprietary blend — the label gives one combined amount (500 mg) without saying how much of each component you get.

This product contains 4 active ingredients: phosphatidylserine (including a phosphatidylserine complex blend), phosphatidylcholine, phosphatidylethanolamine, and phosphatidylinositol. These are all phospholipids—compounds that naturally occur in cell membranes and are thought to support brain function.

The softgel also contains gelatin, glycerin, polyglycitol syrup, and purified water as inactive ingredients to hold everything together.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: attention and cognitive support.
  • We looked for evidence on: Attention deficit-hyperactivity disorder (ADHD), Cognitive function, Memory, Age-related cognitive decline, focus, mental performance — and 1 related terms.
  • The strongest evidence on file: Phosphatidylserine is rated "Possibly Effective" for Age-related cognitive decline (Natural Medicines).
  • Also on file: Phosphatidylcholine is rated "Insufficient Reliable Evidence To Rate" for Memory.
  • Also on file: Phosphatidylserine is rated "Insufficient Reliable Evidence To Rate" for Attention deficit-hyperactivity disorder (ADHD), Cognitive function.

Phosphatidylserine is rated Possibly Effective for age-related cognitive decline and Alzheimer disease. However, evidence is insufficient to rate it for ADHD, general cognitive function, dementia, or athletic performance.

Phosphatidylcholine is rated Possibly Effective for ulcerative colitis, but evidence is insufficient for nonalcoholic fatty liver disease, alcohol-related liver disease, Alzheimer disease, and anxiety. For phosphatidylethanolamine and phosphatidylinositol, effectiveness data isn't established in the facts we hold.

The evidence, ingredient by ingredient Phosphatidylserine Phosphatidylcholine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Phosphatidylserine is generally well tolerated in studies, though long-term safety hasn't been fully established. Common side effects include flatulence, gastrointestinal upset, headache, insomnia (especially at higher doses around 600 mg), and nausea.

Phosphatidylcholine is also generally well tolerated at typical doses, but high amounts can cause bloating, diarrhea, altered taste, nausea, vomiting, sweating, and itching. Pregnancy and breastfeeding: there isn't enough safety information for phosphatidylserine during pregnancy or breastfeeding—avoidance is advised.

For phosphatidylcholine, choline is needed in pregnancy, but supplement safety beyond food sources is not well studied; breastfeeding safety data is also limited—talk with your doctor or pharmacist for personalized guidance.

Side effects, ingredient by ingredient Phosphatidylserine Phosphatidylcholine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — Phosphatidylserine.
  • The most serious interaction on file is rated Moderate.
  • For scale: 219 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your doctor or pharmacist if you use anticholinergic drugs (like antihistamines, antispasmodics, or certain medications for overactive bladder) or cholinergic drugs (which boost acetylcholine). Phosphatidylserine may decrease the effectiveness of anticholinergics or add to the effects of cholinergics.

For the two ingredients we couldn't check—phosphatidylethanolamine and phosphatidylinositol—we hold no interaction data, so search your medications in the tool below.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product may help with age-related cognitive decline or Alzheimer disease, though the evidence is limited. If you take anticholinergic or cholinergic medications, check with your doctor or pharmacist before starting—the phosphatidylserine could interfere with how they work.

Be aware of potential side effects like nausea, headache, and sleep trouble. Pregnant or breastfeeding?

Talk it over with your healthcare provider first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 23, 2016.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about For Attention With Phosphatidylserine Complex, straight from the product label.

Brand Vita+Apps By V
Barcode (UPC) 766536034048
Net contents 90 Softgel(s)
Market status On market
Date entered into DSLD Feb 23, 2016
DSLD ID 56331
Product type Fat/fatty Acid
Supplement form Softgel Capsule
Dietary claims / uses Nutrient, All Other
Intended target group(s) Adult (18 - 50 Years), Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for For Attention With Phosphatidylserine Complex by Vita+Apps By V, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
3 Softgel(s)
UPC/BARCODE
766536034048
IngredientAmount% DV
Phosphatidylserine Complex500 mg--
Phosphatidylserine100 mg--
Phosphatidylcholine25 mg--
Phosphatidylethanolamine2.5 mg--
Phosphatidylinositol1.5 mg--

Other ingredients: Gelatin, Glycerin, Polyglycitol Syrup, purified Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

Dietary Supplement

General Statements

Plus premium subscription to the Pear Focus App

{softgel} actual size

Visit www.vitaminshoppe.com or call 1-888-482-9424 for more information and to reorder.

access code: FPO123456789

Formulation

dairy free nut free

Does not contain: Yeast, Corn, Wheat, Sugar, Salt, Starch, Dairy, Citrus, Fish, Preservatives, Artificial Colors or Flavors.

Formula

Contains: Soy.

For Attention With Phosphatidylserine Complex

Precautions

Contains: Soy.

WARNING: Consult your healthcare provider prior to use if you are pregnant, nursing, taking any medication or have any medical conditions.

KEEP OUT OF REACH OF CHILDREN.

TAMPER EVIDENT Do not use if outer seal is broken or missing.

Suggested/Recommended/Usage/Directions

DIRECTIONS: As a dietary supplement, take one (1) to three (3) softgels daily, preferably between meals.

Storage

STORE IN A COOL, DRY PLACE.

Brand IP Statement(s)

Sharp-PS is a trademark of Enzymotec Corporation.

General

Item No. VS-3404 2041432 FP 6

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

For Attention With Phosphatidylserine Complex by Vita+Apps By V label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

For Attention With Phosphatidylserine Complex label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in For Attention With Phosphatidylserine Complex by Vita+Apps By V

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Amounts shown are per serving.

Phosphatidylserine Complex

Interacts with
219 drugs
500 mg per serving

Phosphatidylserine is a natural fat-like compound found in cell membranes, especially in the brain, and it is sold mainly to support memory and thinki...

Phosphatidylserine Complex monograph & interactions

Other (inactive) ingredients: Gelatin, Glycerin, Polyglycitol Syrup, Purified Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

For Attention With Phosphatidylserine Complex by Vita+Apps By V Drug Interactions

Want to check YOUR meds against For Attention With Phosphatidylserine Complex?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
219Drugs
219 Moderate

Ingredients driving the most interactions

Phosphatidylserine Complex 219

Individual Drug Interactions

The ingredients in For Attention With Phosphatidylserine Complex interact with 219 drugs. Click any drug to see the details.

1 of the 1 ingredient in For Attention With Phosphatidylserine Complex interact with drugs. Each result below shows which ingredient is responsible. Phosphatidylserine Complex

Each ingredient & the kinds of drugs it affects

For each ingredient in For Attention With Phosphatidylserine Complex with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Phosphatidylserine Complex2 drug types · 219 drugs

Anticholinergic Drugs

Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Phosphatidylserine is thought to increase acetylcholine levels, which could theoretically interfere with the activity of anticholinergic agents.

Likelihood Possible Evidence B
Cholinergic Drugs

Theoretically, phosphatidylserine might have additive effects with cholinergic drugs.
Phosphatidylserine is thought to increase acetylcholine levels, which could theoretically lead to additive cholinergic effects when used with cholinergic drugs.

Likelihood Possible Evidence B
Phosphatidylserine Complex full monograph & interactions
The maker

Brand information

Manufacturer and brand details for For Attention With Phosphatidylserine Complex, from the product label.

Vita+Apps By V

See all Vita+Apps By V products
Name
Vitamin Shoppe, Inc.
City
Secaucus
State
NJ
ZipCode
07094
Phone Number
1-888-482-9424
Web Address
www.vitaminshoppe.com
Pharmacist Counseling Corner

For Attention With Phosphatidylserine Complex by Vita+Apps By V: Common Questions

Does For Attention With Phosphatidylserine Complex by Vita+Apps By V interact with any medications?
Yes. Based on its ingredients, For Attention With Phosphatidylserine Complex has a known interaction with 219 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
For Attention With Phosphatidylserine Complex contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
Not without checking first. There isn't enough safety information for phosphatidylserine during pregnancy or breastfeeding, so avoidance is advised. Phosphatidylcholine contains choline, which your body needs in pregnancy, but supplement safety beyond what's in food is not well studied. Talk with your doctor or pharmacist—they can weigh the pros and cons for your situation.
What side effects should I expect?
Most people tolerate it well, but you might notice flatulence, stomach upset, headache, nausea, or trouble sleeping. Insomnia is more likely if you take a higher dose. Phosphatidylcholine can also cause bloating, diarrhea, altered taste, or sweating. If side effects bother you, mention them to your pharmacist.
Does this actually work for attention or ADHD?
Phosphatidylserine has some evidence for age-related cognitive decline and Alzheimer disease, but the evidence isn't strong enough to say whether it helps with ADHD or everyday attention. It's a "possibly effective" rating at best, so results vary.
Why can't you check phosphatidylethanolamine and phosphatidylinositol for interactions?
We don't hold monograph data for those two ingredients yet, so we can't assess their interaction potential. Use the medication checker on this page with your full list, and ask your pharmacist if you have questions about those specific components.
Is this safe to take long-term?
Phosphatidylserine is generally well tolerated, but long-term safety hasn't been fully studied. If you plan to take it for months or longer, talk it over with your doctor or pharmacist to make sure it's the right choice for you.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

For Attention With Phosphatidylserine Complex label
Go deeper

The Full Monographs Behind For Attention With Phosphatidylserine Complex’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Phosphatidylserine

Interacts with 219 drugs

Phosphatidylserine is a natural fat-like compound found in cell membranes, especially in the brain, and it is sold mainly to support memory and thinking. Some research suggests possible bene...

Read the full Phosphatidylserine monograph → Herb & supplement monograph

Phosphatidylcholine

Phosphatidylcholine is a phospholipid that is part of every cell membrane and a source of choline. People take it for liver, brain, and gut health, but solid human evidence is limited for mo...

Read the full Phosphatidylcholine monograph →
Sources

Sources & How We Checked

For Attention With Phosphatidylserine Complex's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 24 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Phosphatidylserine 9 references
  1. Crook T, Petrie W, Wells C, Massari DC. Effects of phosphatidylserine in Alzheimer's disease. Psychopharmacol Bull 1992;28:61-6.
  2. Pepping J. Phosphatidylserine. Am J Health-Syst Pharm 1999;56:2038,2043-4.
  3. Kidd PM. Phosphatidylserine; Membrane nutrient for memory. A clinical and mechanistic assessment. Altern Med Rev 1996;1:70-84.
  4. Kim HY, Akbar M, Lau A, et al. Inhibition of neuronal apoptosis by docosahexaenoic acid (22:6n-3). Role of phosphatidylserine in antiapoptotic effect. J Biol Chem 2000;275:35215-23.. PubMed
  5. Zanotti A, Valzelli L, Toffano G. Chronic phosphatidylserine treatment improves spatial memory and passive avoidance in aged rats. Psychopharmacology (Berl) 1989;99:316-21.. PubMed
  6. Schreiber S, Kampf-Sherf O, Gorfine M, et al. An open trial of plant-source derived phosphatydilserine for treatment of age-related cognitive decline. Isr J Psychiatry Relat Sci 2000;37:302-7.
  7. Pepping, J. Phosphatidylserine. Am J Health Syst.Pharm. 10-15-1999;56(20):2038, 2043-2038, 2044.
  8. Monteverde, A., Gnemmi, P., Rossi, F., Monteverde, A., and Finali, G. C. Selegiline in the treatment of mild to moderate Alzheimer-type dementia. Clin.Ther 1990;12(4):315-322.
  9. Vakhapova V, Cohen T, Richter Y, Herzog Y, Kam Y, Korczyn AD. Phosphatidylserine containing omega-3 Fatty acids may improve memory abilities in nondemented elderly individuals with memory complaints: results from an open-label extension study. Dement Geri PubMed

See these in context on the Phosphatidylserine monograph →

Phosphatidylcholine 15 references
  1. Domino EF, May WW, Demetriou S, et al. Lack of clinically significant improvement of patients with tardive dyskinesia following phosphatidylcholine therapy. Biol Psychiatry 1985;20:1189-96. PubMed
  2. Aronson PJ, Lorincz AL. Promotion of palmar sweating with oral phosphatidylcholine. Acta Derm Venereol 1985;65:19-24. DOI
  3. Hexsel DM, Serra M, de Oliveira Dal'Forno T, et al. Cosmetic uses of injectable phosphatidylcholine on the face. Otolaryngol Clin North Am 2005;38:1119-29. PubMed
  4. Kopera D, Binder B, Toplak H, et al. Histopathologic changes after intralesional application of phosphatidylcholine for lipoma reduction: report of a case. Am J Dermatopathol 2006;28:331-3. PubMed
  5. Rittes PG. The use of phosphatidylcholine for correction of lower lid bulging due to prominent fat pads. Dermatol Surg 2001;27:391-2. PubMed
  6. Rotunda AM, Kolodney MS. Mesotherapy and phosphatidylcholine injections: historical clarification and review. Dermatol Surg 2006;32:465-80. PubMed
  7. Hexsel D, Serra M, Mazzuco R, et al. Phosphatidylcholine in the treatment of localized fat. J Drugs Dermatol 2003;2:511-8.
  8. Hasengschwandtner F. Phosphatidylcholine treatment to induce lipolysis. Cosmet Dermatol 2005;4:308-13. PubMed
  9. Rittes PG. The use of phosphatidylcholine for correction of localized fat deposits. Aesthetic Plast Surg 2003;27:315-8. PubMed
  10. Ablon G, Rotunda AM. Treatment of lower eyelid fat pads using phosphatidylcholine: clinical trial and review. Dermatol Surg 2004;30:422-7. PubMed
  11. Loguercio C, Andreone P, Brisc C, et al. Silybin combined with phosphatidylcholine and vitamin E in patients with nonalcoholic fatty liver disease: a randomized controlled trial. Free Radic Biol Med 2012;52(9):1658-65. PubMed
  12. Panos, J. M., Palson, R., Johnson, R., Portmann, B., and Williams, R. Polyunsaturated phosphatidylcholine for acute alcoholic hepatitis: a double blind randomized placebo controlled trial. Eur.J.Gastroenterol 1990;2:351-355.
  13. Stremmel W, Braun A, Hanemann A, Ehehalt R, Autschbach F, Karner M. Delayed release phosphatidylcholine in chronic-active ulcerative colitis: a randomized, double-blinded, dose finding study. J Clin Gastroenterol 2010;44(5):e101-7. PubMed
  14. Stremmel W, Ehehalt R, Autschbach F, Karner M. Phosphatidylcholine for steroid-refractory chronic ulcerative colitis: a randomized trial. Ann Intern Med. 2007;147(9):603-10. PubMed
  15. Stremmel W, Vural H, Evliyaoglu O, Weiskirchen R. Delayed Release Phosphatidylcholine is Effective for Treatment of Ulcerative Colitis: A Meta-Analysis. Dig Dis 2021;39(5):508-515. PubMed

See these in context on the Phosphatidylcholine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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