Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Full Spectrum Beet Leaf 400 mg Ingredients & Drug Interactions

by Swanson Premium Brand

Capsule Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Full Spectrum Beet Leaf 400 mg is a dietary supplement by Swanson Premium Brand with 1 active ingredient. Its ingredients are commonly taken for high blood pressure, exercise and athletic performance, heart and circulation support.Based on those ingredients, 861 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Beet. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Full Spectrum Beet Leaf 400 mg by Swanson Premium Brand

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: beet leaf at 400 mg per capsule. The capsule itself is made with gelatin, rice flour, magnesium stearate, and silica — inactive ingredients that help deliver the beet powder.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Beet's overall clinical evidence instead.

Moderate

Some clinical evidence supports Beet for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Athletic performance — rated "Possibly Effective" (Natural Medicines).
  • On file: Exercise-induced muscle soreness — rated "Possibly Effective" (Natural Medicines).

Beet shows possibly effective evidence for athletic performance and exercise-induced muscle soreness. The data on its use for chronic obstructive pulmonary disease (COPD) points to possibly ineffective.

For cholesterol management (dyslipidemia) and brain function (cognitive function), we don't have reliable evidence yet to rate whether it works.

The evidence, ingredient by ingredient Beet

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Beet eaten as a food is widely consumed and generally well tolerated by most adults. When it comes to concentrated supplements like this one, safety data is limited, so use caution.

Short-term use of beet for medicinal purposes appears well tolerated overall. The most common side effect is red-colored stools and urine — harmless and temporary.

Rarely, black stools have been reported. In very large amounts, beet theoretically could lower calcium levels (hypocalcemia) or cause kidney damage, though these are uncommon.

There isn't enough data on file regarding safety during breastfeeding — talk with your doctor or pharmacist about whether this product is right for you if you're nursing.

Side effects, ingredient by ingredient Beet

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Beet.
  • The most serious interaction on file is rated Moderate.
  • For scale: 862 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check whether you take any drugs broken down by the liver enzyme CYP3A4 — beet may raise their levels (Moderate severity). Also confirm you're not on blood pressure medications, since beet's nitrate content could theoretically lower pressure further (Minor).

If you take CYP1A2 substrates, those levels might decrease (Minor). Your pharmacist can look up your exact medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

If you're an athlete or recovering from exercise soreness and want to try beet for possibly effective support, this is a reasonable option. Because it can affect how your liver processes over 800 medications, you must check your exact prescriptions against the interaction tool before you start.

Talk with your doctor or pharmacist about whether the potential benefits outweigh any risks for your situation, especially if you take blood pressure or heart medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jan 25, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Full Spectrum Beet Leaf 400 mg, straight from the product label.

Brand Swanson Premium Brand
Barcode (UPC) 087614112879
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Jan 25, 2020
DSLD ID 212601
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Full Spectrum Beet Leaf 400 mg by Swanson Premium Brand, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
UPC/BARCODE
087614112879
IngredientAmount% DV
Beet400 mg--

Other ingredients: Gelatin, Rice Flour, Magnesium Stearate, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Bringing wellness to the world since 1969

To reorder, call toll free 1-800-437-4148 or visit our website at www.swansonvitamins.com

FDA Statement of Identity

Herbal Supplement

Seals/Symbols

Guaranteed purity & potency

Precautions

Do not use if seal is broken.

Keep out of reach of children.

Storage

Store in a cool, dry place.

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, take one capsule one to two times per day with water.

See for yourself

Full Spectrum Beet Leaf 400 mg by Swanson Premium Brand label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Full Spectrum Beet Leaf 400 mg by Swanson Premium Brand

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.

Beet

Interacts with
861 drugs
400 mg per serving

Beet, especially beetroot juice, is a nitrate-rich food that may modestly lower blood pressure and slightly improve exercise performance in some peopl...

Beet monograph & interactions

Other (inactive) ingredients: Gelatin, Rice Flour, Magnesium Stearate, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Full Spectrum Beet Leaf 400 mg by Swanson Premium Brand Drug Interactions

Want to check YOUR meds against Full Spectrum Beet Leaf 400 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
861Drugs
643 Moderate 218 Minor

Ingredients driving the most interactions

Beet 861

Each ingredient & the kinds of drugs it affects

For each ingredient in Full Spectrum Beet Leaf 400 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Beet3 drug types · 861 drugs

Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, beet might increase the levels of CYP3A4 substrates.
In vitro research suggests that betanin, the major pigment in beet, competitively inhibits CYP3A4 in a dose-dependent manner similarly to strong CYP3A4 inhibitor ketoconazole.

Likelihood Possible Evidence D
Antihypertensive Drugs

Beet and beetroot contain nitrates, which can cause vasodilation, potentially leading to lower blood pressure. However, a study published in the European Journal of Clinical Nutrition using concentrated beetroot juice found no significant impact on blood pressure or heart rate in different age groups. Other small clinical studies suggest that while beet consumption might transiently lower blood pressure due to vessel dilation, there's no consistent evidence of a lasting effect. Overall, the theoretical risk of reduced blood pressure due to beet's nitrate content exists, but studies generally indicate a low and temporary impact rather than a sustained decrease.

Likelihood Possible Evidence A
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, beet might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research suggests that beet induces CYP1A2 enzymes.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Full Spectrum Beet Leaf 400 mg, from the product label.

Swanson Premium Brand

See all Swanson Premium Brand products
Name
Swanson Health Products
City
Fargo
State
ND
ZipCode
58104
Phone Number
1-800-437-4148
Web Address
www.swansonvitamins.com
Pharmacist Counseling Corner

Full Spectrum Beet Leaf 400 mg by Swanson Premium Brand: Common Questions

Does Full Spectrum Beet Leaf 400 mg by Swanson Premium Brand interact with any medications?
Yes. Based on its ingredients, Full Spectrum Beet Leaf 400 mg has a known interaction with 861 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Full Spectrum Beet Leaf 400 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does beet really help with athletic performance?
Research suggests it's possibly effective for athletic performance and for reducing soreness after exercise. The evidence isn't overwhelming, but beet has enough clinical support to be worth trying if you're interested.
Why might my stools turn red or black after taking this?
Red coloring is the most common side effect and is harmless — it's just beet pigment passing through. Black stools have also been reported rarely. Neither means anything is wrong, but if you're on blood thinners and see black stools, mention it to your doctor to rule out bleeding.
Is concentrated beet supplement as safe as eating beets?
Beet as food is generally well tolerated, but concentrated supplements don't have the same safety track record. Use caution with this form, and stick to short-term use unless your doctor advises otherwise.
Can I take this if I'm on blood pressure medicine?
Beet contains nitrates that can relax blood vessels and lower pressure. While a clinical study of beetroot juice showed no major effect, the theoretical risk is there — check with your doctor or pharmacist before combining it with blood pressure drugs.
What should I do if I take a lot of medications?
Use the medication interaction checker on this page to search each of your prescriptions. Because beet affects how your liver processes over 860 medications, it's especially important to confirm your specific drugs are safe to combine with it.
Is this safe to take while breastfeeding?
We don't have enough safety data on concentrated beet supplements during breastfeeding. Talk with your doctor or pharmacist about whether this product is right for you if you're nursing.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Full Spectrum Beet Leaf 400 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Full Spectrum Beet Leaf 400 mg label
Go deeper

The Full Monographs Behind Full Spectrum Beet Leaf 400 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Full Spectrum Beet Leaf 400 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 14 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Beet 14 references
  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  2. Clifford T, Berntzen B, Davison GW, et al. Effects of beetroot juice on recovery of muscle function and performance between bouts of repeated sprint exercise. Nutrients 2016;8. pii: E506. PubMed
  3. Siervo M, Lara J, Ogbonmwan I, Mathers JC. Inorganic nitrate and beetroot juice supplementation reduces blood pressure in adults: a systematic review and meta-analysis. J Nutr 2013;143:818-26. PubMed
  4. Clifford T, Howatson G, West DJ, Stevenson EJ. Beetroot juice is more beneficial than sodium nitrate for attenuating muscle pain after strenuous eccentric-bias exercise. Appl Physiol Nutr Metab. 2017;42(11):1185-1191. PubMed
  5. Clifford T, Bell O, West DJ, Howatson G, Stevenson EJ. The effects of beetroot juice supplementation on indices of muscle damage following eccentric exercise. Eur J Appl Physiol. 2016;116(2):353-62. PubMed
  6. Wylie LJ, Kelly J, Bailey SJ, et al. Beetroot juice and exercise: pharmacodynamic and dose-response relationships. J Appl Physiol (1985). 2013;115(3):325-36. PubMed
  7. Garnacho-Castaño MV, Palau-Salvà G, Cuenca E, et al. Effects of a single dose of beetroot juice on cycling time trial performance at ventilatory thresholds intensity in male triathletes. J Int Soc Sports Nutr. 2018;15(1):49. PubMed
  8. Rasica L, Porcelli S, Marzorati M, et al. Ergogenic effects of beetroot juice supplementation during severe-intensity exercise in obese adolescents. Am J Physiol Regul Integr Comp Physiol. 2018;315(3):R453-R460. PubMed
  9. Henrohn D, Björkstrand K, Lundberg JO, et al. Effects of oral supplementation with nitrate-rich beetroot juice in patients with pulmonary arterial hypertension-results from BEET-PAH, an exploratory randomized, double-blind, placebo-controlled, crosso
  10. Serra-Payá N, Garnacho-Castaño MV, Sánchez-Nuño S, et al. The relationship between resistance exercise performance and ventilatory efficiency after beetroot juice intake in well-trained athletes. Nutrients 2021;13(4):1094. PubMed
  11. Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed
  12. Hemmatinafar M, Zaremoayedi L, Koushkie Jahromi M, et al. Effect of Beetroot Juice Supplementation on Muscle Soreness and Performance Recovery after Exercise-Induced Muscle Damage in Female Volleyball Players. Nutrients 2023;15(17):3763. PubMed
  13. Lim SH, Bae S, Lee HS, Han HK, Choi CI. Effect of Betanin, the Major Pigment of Red Beetroot (Beta vulgaris L.), on the Activity of Recombinant Human Cytochrome P450 Enzymes. Pharmaceuticals (Basel) 2023;16(9):1224. PubMed
  14. Oscherwitz M, Tamayo RM, Heudebert A, Centor R. A Case of Pseudo-Hematochezia from Beet Supplement Ingestion. Am J Med 2023;136(9):e177-e178. PubMed

See these in context on the Beet monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring