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Dietary supplement

GABA 60 Capsules Ingredients & Drug Interactions

by Adaptogen Research

GABA 60 Capsules label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking GABA 60 Capsules against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

GABA 60 Capsules is a dietary supplement by Adaptogen Research with 1 active ingredient. Its ingredients are commonly taken for anxiety and stress, sleep problems, relaxation.Based on those ingredients, 419 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are GABA. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against GABA 60 Capsules by Adaptogen Research

Ask about any prescription or over-the-counter medication and we check it for interactions with GABA 60 Capsules by Adaptogen Research — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of GABA 60 Capsules by Adaptogen Research

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 30, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: GABA (gamma-aminobutyric acid), a compound your brain naturally produces to help regulate nerve activity and promote relaxation. The capsule also contains three inactive ingredients — a vegetarian capsule shell, ascorbyl palmitate (a form of vitamin C used as a preservative), and silicon dioxide (an anti-caking agent).

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Gamma-aminobutyric Acid (gaba)'s own graded uses on its monograph.

Why this rating?
  • The label markets this product for: Calm mind support.
  • We looked for evidence on: Anxiety, Stress.
  • The closest evidence on file: Gamma-aminobutyric Acid (gaba) is rated "Insufficient Reliable Evidence To Rate" for Anxiety (Natural Medicines).
  • Also on file: Gamma-aminobutyric Acid (gaba) is rated "Insufficient Reliable Evidence To Rate" for Post-traumatic stress disorder (PTSD).

The evidence for GABA isn't established yet for the conditions it's marketed for. The data we hold shows insufficient evidence to rate it for anxiety, ADHD, athletic performance, cerebral palsy, and chronic bronchitis.

That doesn't mean it doesn't work — it means reliable studies haven't confirmed whether it does. If you're thinking about trying it for a specific reason, talk with your doctor or pharmacist about what the current research actually shows.

The evidence, ingredient by ingredient Gamma-aminobutyric Acid (gaba)

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Orally, GABA is generally well tolerated short-term, but long-term safety hasn't been well studied. The most common side effects reported are drowsiness, nausea, gastric upset, minor throat burning, and muscle weakness.

One case reported a temporary loss of menstruation in a person who took GABA with phosphatidylserine. Because safety data is limited, the product facts advise caution and recommend you only use it if your doctor advises otherwise.

There isn't enough safety information available for breastfeeding — talk with your doctor or pharmacist for personalized guidance.

Side effects, ingredient by ingredient Gamma-aminobutyric Acid (gaba)

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Gamma-aminobutyric Acid (gaba).
  • The most serious interaction on file is rated Moderate.
  • For scale: 419 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check before taking this if you use blood pressure medications — GABA may lower blood pressure further. Also flag any CNS depressants you take (sedatives, sleep aids, anti-anxiety drugs, or prescription pain relievers) because adding GABA might increase drowsiness, though the real-world risk isn't clear.

Talk with your doctor or pharmacist about your full medication list.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

GABA might appeal to someone interested in relaxation or sleep support, but the evidence for those uses isn't solid yet. If you take blood pressure medication or any sedating drugs, check with your doctor or pharmacist before adding this — the interactions could matter.

Long-term safety data is thin, so this isn't a take-forever supplement without expert input. Your own doctor or pharmacist can help you decide if it's right for you and your medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 22, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about GABA 60 Capsules, straight from the product label.

Brand Adaptogen Research
Barcode (UPC) 828054774377
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Apr 22, 2021
DSLD ID 247003
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for GABA 60 Capsules by Adaptogen Research, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
UPC/BARCODE
828054774377
IngredientAmount% DV
GABA420 mg--

Other ingredients: Vegetarian Capsule, Ascorbyl Palmitate, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Calm Mind

Free of the following common allergens: Milk/casein, eggs, fish, shellfish, tree nuts, peanuts, wheat, gluten, soybeans, corn, and yeast. Contains no artificial colors, flavors or preservatives.

Notice: Color, size or shape may appear different between lots.

FDA Statement of Identity

Dietary Supplement

General Statements

Professional Use Only

Produced under a strict quality management system in compliance with Good Manufacturing Practices (GMPs) and third party quality certifications.

Precautions

Report any adverse reactions to (302) 213-0030

Do not use if shrinkwrap is broken or missing.

Keep out of reach of children.

Suggested/Recommended/Usage/Directions

Suggested Use: 1 Capsule, 2 to 4 times daily between meals or as directed by a healthcare practitioner.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Storage

Store in a cool, dry place (59 degrees F-85 degrees F) away from direct sunlight.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

GABA 60 Capsules by Adaptogen Research label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

GABA 60 Capsules label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in GABA 60 Capsules by Adaptogen Research

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

GABA

Interacts with
419 drugs
420 mg per serving

GABA is a calming chemical messenger (neurotransmitter) that your body makes on its own, and it is sold as a supplement for stress, anxiety, and sleep...

GABA monograph & interactions

Other (inactive) ingredients: Vegetarian Capsule, Ascorbyl Palmitate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

GABA 60 Capsules by Adaptogen Research Drug Interactions

Want to check YOUR meds against GABA 60 Capsules?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
419Drugs
172 Moderate 247 Minor

Ingredients driving the most interactions

GABA 419

Individual Drug Interactions

The ingredients in GABA 60 Capsules interact with 419 drugs. Click any drug to see the details.

1 of the 1 ingredient in GABA 60 Capsules interact with drugs. Each result below shows which ingredient is responsible. GABA

Each ingredient & the kinds of drugs it affects

For each ingredient in GABA 60 Capsules with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

GABA2 drug types · 419 drugs

Antihypertensive Drugs

Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.
Some clinical research shows that GABA can decrease blood pressure in patients with hypertension.

Likelihood Possible Evidence B
Cns Depressants

Theoretically, GABA might have additive sedative effects when used in conjunction with CNS depressants. However, it is unclear if this concern is clinically relevant.
Endogenous GABA has well-established relaxant effects and GABA(A) receptors have an established physiological role in sleep. However, the effects of GABA supplements are unclear, as it is unknown whether exogenous GABA crosses the blood-brain barrier. Although there have been limited reports of drowsiness or tiredness with GABA supplements, these effects have not been widely reported in clinical studies. Additionally, intravenous GABA 0.1-1 mg/kg has been shown to induce anxiety in a dose-dependent manner.

Likelihood Unlikely Evidence D
GABA full monograph & interactions
The maker

Brand information

Manufacturer and brand details for GABA 60 Capsules, from the product label.

Adaptogen Research

See all Adaptogen Research products
Name
Adaptogen Research
Street Address
625 Barksdale Road, Suite 113
City
Newark
State
DE
ZipCode
19711
Phone Number
302-213-0030
Pharmacist Counseling Corner

GABA 60 Capsules by Adaptogen Research: Common Questions

Does GABA 60 Capsules by Adaptogen Research interact with any medications?
Yes. Based on its ingredients, GABA 60 Capsules has a known interaction with 419 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
GABA 60 Capsules contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is GABA and what does it do in the body?
GABA (gamma-aminobutyric acid) is a chemical your brain naturally makes to help calm nerve activity. It's involved in relaxation and sleep. This supplement is meant to add more of it from the outside, though how well oral GABA actually reaches the brain and works isn't completely clear.
What side effects has GABA been reported to cause?
The most common ones from oral GABA are drowsiness, nausea, stomach upset, minor throat burning, and muscle weakness. One person taking GABA with another supplement reported temporary loss of menstruation. Overall, it seems well tolerated in short-term use, but long-term safety data is limited.
Is there proof that GABA actually works for anxiety or ADHD?
Not yet. The data we have shows insufficient evidence to rate GABA for anxiety, ADHD, athletic performance, cerebral palsy, or chronic bronchitis. That means reliable studies haven't confirmed it works for those uses — so if you're considering it for one of these reasons, have a conversation with your doctor or pharmacist first.
Is GABA safe to take if I'm breastfeeding?
There isn't enough safety information to know. The facts advise against it while breastfeeding. Talk with your doctor or pharmacist — they can weigh the specifics of your situation and help you decide what's right for you and your baby.
Can I take GABA long-term?
It's often well tolerated in the short term, but long-term safety hasn't been well studied. If you're thinking about taking it regularly for months or longer, check with your doctor or pharmacist first to see if that's a good fit for you.
What's in the capsule besides GABA?
The capsule itself is vegetarian, and there are two other inactive ingredients: ascorbyl palmitate (a preservative) and silicon dioxide (an anti-caking agent). These are just there to keep the supplement stable and in capsule form — they're not active ingredients.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

GABA 60 Capsules label
Go deeper

The Full Monographs Behind GABA 60 Capsules’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Gamma-aminobutyric Acid (gaba)

Interacts with 419 drugs

GABA is a calming chemical messenger (neurotransmitter) that your body makes on its own, and it is sold as a supplement for stress, anxiety, and sleep. The science behind oral GABA supplemen...

Read the full Gamma-aminobutyric Acid (gaba) monograph →
Sources

Sources & How We Checked

GABA 60 Capsules's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Gamma-aminobutyric Acid (gaba) 12 references
  1. Cavagnini F, Invitti C, Pinto M, et al. Effect of acute and repeated administration of gamma aminobutyric acid (GABA) on growth hormone and prolactin secretion in man. Acta Endocrinol (Copenh) 1980;93:149-54.
  2. Nurnberger JI Jr, Berrettini WH, Simmons-Alling S, et al. Intravenous GABA administration is anxiogenic in man. Psychiatry Res 1986;19:113-7. PubMed
  3. Gershman RN, Vasilenko MA, Iliushina GG, et al. [Gammalon in the rehabilitation in infantile cerebral palsy]. Pediatr.Akus.Ginekol. 1977;(6):26-7.
  4. Loeb C, Benassi E, Bo, GP, et al. Preliminary evaluation of the effect of GABA and phosphatidylserine in epileptic patients. Epilepsy Res. 1987;1:209-12 . PubMed
  5. Inoue K, Shirai T, Ochiai H, et al. Blood-pressure-lowering effect of a novel fermented milk containing gamma-aminobutyric acid (GABA) in mild hypertensives. Eur J Clin Nutr 2003;57:490-95.
  6. ELLIOTT, K. A. and JASPER, H. H. Gammaaminobutyric acid. Physiol Rev. 1959;39(2):383-406.
  7. Winsky-Sommerer, R. Role of GABAA receptors in the physiology and pharmacology of sleep. Eur.J.Neurosci. 2009;29(9):1779-1794.
  8. Meldrum, B. S. GABAergic mechanisms in the pathogenesis and treatment of epilepsy. Br.J.Clin.Pharmacol. 1989;27 Suppl 1:3S-11S. PubMed
  9. Loeb, C., Marinari, U. M., Benassi, E., Besio, G., Cottalasso, D., Cupello, A., Maffini, M., Mainardi, P., Pronzato, M. A., and Scotto, P. A. Phosphatidylserine increases in vivo the synaptosomal uptake of exogenous GABA in rats. Exp.Neurol. 1988;99(2):4 PubMed
  10. Melis, G. B., Paoletti, A. M., Mais, V., and Fioretti, P. Interference of dopamine infusion on gamma-amino butyric acid (GABA)-stimulated prolactin increase. J.Endocrinol.Invest 1980;3(4):445-448.
  11. Boonstra E, de Kleijn R, Colzato LS, Alkemade A, Forstmann BU, Nieuwenhuis S. Neurotransmitters as food supplements: the effects of GABA on brain and behavior. Front Psychol. 2015 Oct 6;6:1520. doi: 10.3389/fpsyg.2015.01520. eCollection 2015. PubMed
  12. de Bie TH, Witkamp RF, Balvers MG, Jongsma MA. Effects of ?-aminobutyric acid supplementation on glucose control in adults with prediabetes: A double-blind, randomized, placebo-controlled trial. Am J Clin Nutr 2023;118(3):708-719. PubMed

See these in context on the Gamma-aminobutyric Acid (gaba) monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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