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Dietary supplement

GABA Unflavored Ingredients & Drug Interactions

by Dymatize

GABA Unflavored label
See full label image
Powder Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking GABA Unflavored against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

GABA Unflavored is a dietary supplement by Dymatize with 1 active ingredient. Its ingredients are commonly taken for anxiety and stress, sleep problems, relaxation.Based on those ingredients, 419 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Gamma Aminobutyric Acid. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against GABA Unflavored by Dymatize

Ask about any prescription or over-the-counter medication and we check it for interactions with GABA Unflavored by Dymatize — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of GABA Unflavored by Dymatize

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 30, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Dymatize GABA Unflavored is a single-ingredient powder: gamma-aminobutyric acid, or GABA. It's a neurotransmitter — a chemical messenger your brain uses naturally to promote relaxation and calm.

The product contains no inactive fillers or other ingredients.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Gamma-aminobutyric Acid (gaba)'s own graded uses on its monograph.

Why this rating?
  • The label markets this product for: supports relaxation and calming.
  • We looked for evidence on: Anxiety, Stress, Insomnia, emotional balance, nervousness.
  • The closest evidence on file: Gamma-aminobutyric Acid (gaba) is rated "Insufficient Reliable Evidence To Rate" for Anxiety (Natural Medicines).
  • Also on file: Gamma-aminobutyric Acid (gaba) is rated "Insufficient Reliable Evidence To Rate" for Insomnia, Post-traumatic stress disorder (PTSD).

The evidence for GABA supplement effectiveness isn't established in the data we hold. The product's ingredient is listed as having insufficient reliable evidence to rate for conditions including anxiety, ADHD, athletic performance, cerebral palsy, and chronic bronchitis.

That means studies haven't yet proven whether oral GABA supplements work for these purposes — not that they don't, just that the evidence isn't there yet.

The evidence, ingredient by ingredient Gamma-aminobutyric Acid (gaba)

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

GABA is generally well tolerated in the short term when taken by mouth, though a full safety evaluation hasn't been done. The most common side effects reported are drowsiness, stomach upset, minor throat burning, muscle weakness, and nausea.

Long-term safety hasn't been studied well, so use beyond short-term periods should be discussed with your doctor. One case reported a temporary loss of menstrual periods (amenorrhea) when GABA was combined with another supplement.

There isn't enough safety information to recommend GABA during pregnancy or while breastfeeding — talk with your doctor or pharmacist about whether it's right for you in either situation.

Side effects, ingredient by ingredient Gamma-aminobutyric Acid (gaba)

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Gamma-aminobutyric Acid (gaba).
  • The most serious interaction on file is rated Moderate.
  • For scale: 419 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Double-check before starting if you take blood pressure medications — GABA may lower your blood pressure further, and you'll want your doctor to monitor you. Also check if you're on any central nervous system depressants like sleep aids or certain anxiety medications, since additive sedation is theoretically possible, though the real-world risk is unclear.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

GABA Unflavored might be worth considering if you're curious about its potential for relaxation, but the evidence that it actually works for anxiety, sleep, or athletic performance isn't solid yet. Be cautious if you take blood pressure or sleep medications — you'll want to check with your doctor or pharmacist first to make sure it's safe to combine.

Long-term use hasn't been well studied, so keep that conversation going with your healthcare provider.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jan 25, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about GABA Unflavored, straight from the product label.

Brand Dymatize
Barcode (UPC) 705016461103
Net contents 3.92 oz.; 111 Gram(s)
Market status On market
Date entered into DSLD Jan 25, 2018
DSLD ID 83014
Product type Non-nutrient/non-botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for GABA Unflavored by Dymatize, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Gram(s)
Maximum serving Sizes:
2 Gram(s)
Servings per container
56
UPC/BARCODE
705016461103
IngredientAmount% DV
Gamma Aminobutyric Acid2 Gram(s)--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Supports relaxation. Fast absorbing. GABA (gamma aminobutyric acid) is a non-essential amino acid that functions in the body as a neurotransmitter and is associated with calming properties.

Sold by weight no volume

56 servings

Produced in the USA with international ingredients

Formula

Known for quality and proven performance, Dymatize GABA is the choice of athletes and serious trainers worldwide.

Gamma Aminobutyric Acid

Suggested/Recommended/Usage/Directions

Dymatize GABA mixes easily and can be used by itself or blended into shakes or other beverages.

Directions: Mix 1 scoop with 4 fl. oz. of cold water or your favorite beverage.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Brand IP Statement(s)

Get Dymatized

FDA Statement of Identity

Dietary Supplement

Formulation

Gluten free/No dyes

Precautions

Keep out of the reach of children.

Consult a physician prior to use if you have any medical condition or are pregnant or lactating.

Use only as directed.

Storage

Storage Conditions: Store in a cool, dry place.

General

REV002

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

GABA Unflavored by Dymatize label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

GABA Unflavored label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in GABA Unflavored by Dymatize

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Gram(s) Dosage formPowder Servings per container56 Amounts shown are per serving.

Gamma Aminobutyric Acid

Interacts with
419 drugs
2 Gram(s) per serving

GABA is a calming chemical messenger (neurotransmitter) that your body makes on its own, and it is sold as a supplement for stress, anxiety, and sleep...

Gamma Aminobutyric Acid monograph & interactions
Interaction report

GABA Unflavored by Dymatize Drug Interactions

Want to check YOUR meds against GABA Unflavored?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
419Drugs
172 Moderate 247 Minor

Ingredients driving the most interactions

Gamma Aminobutyric Acid 419

Individual Drug Interactions

The ingredients in GABA Unflavored interact with 419 drugs. Click any drug to see the details.

1 of the 1 ingredient in GABA Unflavored interact with drugs. Each result below shows which ingredient is responsible. Gamma Aminobutyric Acid

Each ingredient & the kinds of drugs it affects

For each ingredient in GABA Unflavored with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Gamma Aminobutyric Acid2 drug types · 419 drugs

Antihypertensive Drugs

Theoretically, taking GABA with antihypertensive drugs might increase the risk of hypotension.
Some clinical research shows that GABA can decrease blood pressure in patients with hypertension.

Likelihood Possible Evidence B
Cns Depressants

Theoretically, GABA might have additive sedative effects when used in conjunction with CNS depressants. However, it is unclear if this concern is clinically relevant.
Endogenous GABA has well-established relaxant effects and GABA(A) receptors have an established physiological role in sleep. However, the effects of GABA supplements are unclear, as it is unknown whether exogenous GABA crosses the blood-brain barrier. Although there have been limited reports of drowsiness or tiredness with GABA supplements, these effects have not been widely reported in clinical studies. Additionally, intravenous GABA 0.1-1 mg/kg has been shown to induce anxiety in a dose-dependent manner.

Likelihood Unlikely Evidence D
Gamma Aminobutyric Acid full monograph & interactions
The maker

Brand information

Manufacturer and brand details for GABA Unflavored, from the product label.

Dymatize

See all Dymatize products
Name
Dymatize Enterprises, LLC
City
Dallas
State
TX
ZipCode
75207
Phone Number
(888) 334-5326
Web Address
Dymatize.com
Pharmacist Counseling Corner

GABA Unflavored by Dymatize: Common Questions

Does GABA Unflavored by Dymatize interact with any medications?
Yes. Based on its ingredients, GABA Unflavored has a known interaction with 419 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
GABA Unflavored contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does GABA actually help with anxiety?
The data we hold shows insufficient reliable evidence to say whether GABA supplements work for anxiety. Your body makes GABA naturally as a calming neurotransmitter, but whether taking it as a supplement actually changes anxiety hasn't been proven yet.
What are the main side effects I might feel?
The most common ones are drowsiness, stomach upset, minor throat burning, muscle weakness, and nausea. Keep in mind that a thorough safety evaluation hasn't been done, so other effects may occur that we don't know about yet.
Is this safe to take long-term?
GABA seems well tolerated in the short term, but long-term safety hasn't been well studied. If you're thinking about taking it regularly, talk with your doctor about what makes sense for you.
Can I take this while pregnant or breastfeeding?
There isn't enough safety information to know either way. Talk with your doctor or pharmacist about whether it's right for you in pregnancy or while breastfeeding — they can give you personalized advice.
Why is this just powder with no other ingredients?
This product is GABA by itself with no fillers, binders, or other additives — you're getting the active ingredient and nothing else.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if GABA Unflavored is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

GABA Unflavored label
Go deeper

The Full Monographs Behind GABA Unflavored’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Gamma-aminobutyric Acid (gaba)

Interacts with 419 drugs

GABA is a calming chemical messenger (neurotransmitter) that your body makes on its own, and it is sold as a supplement for stress, anxiety, and sleep. The science behind oral GABA supplemen...

Read the full Gamma-aminobutyric Acid (gaba) monograph →
Sources

Sources & How We Checked

GABA Unflavored's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Gamma-aminobutyric Acid (gaba) 12 references
  1. Cavagnini F, Invitti C, Pinto M, et al. Effect of acute and repeated administration of gamma aminobutyric acid (GABA) on growth hormone and prolactin secretion in man. Acta Endocrinol (Copenh) 1980;93:149-54.
  2. Nurnberger JI Jr, Berrettini WH, Simmons-Alling S, et al. Intravenous GABA administration is anxiogenic in man. Psychiatry Res 1986;19:113-7. PubMed
  3. Gershman RN, Vasilenko MA, Iliushina GG, et al. [Gammalon in the rehabilitation in infantile cerebral palsy]. Pediatr.Akus.Ginekol. 1977;(6):26-7.
  4. Loeb C, Benassi E, Bo, GP, et al. Preliminary evaluation of the effect of GABA and phosphatidylserine in epileptic patients. Epilepsy Res. 1987;1:209-12 . PubMed
  5. Inoue K, Shirai T, Ochiai H, et al. Blood-pressure-lowering effect of a novel fermented milk containing gamma-aminobutyric acid (GABA) in mild hypertensives. Eur J Clin Nutr 2003;57:490-95.
  6. ELLIOTT, K. A. and JASPER, H. H. Gammaaminobutyric acid. Physiol Rev. 1959;39(2):383-406.
  7. Winsky-Sommerer, R. Role of GABAA receptors in the physiology and pharmacology of sleep. Eur.J.Neurosci. 2009;29(9):1779-1794.
  8. Meldrum, B. S. GABAergic mechanisms in the pathogenesis and treatment of epilepsy. Br.J.Clin.Pharmacol. 1989;27 Suppl 1:3S-11S. PubMed
  9. Loeb, C., Marinari, U. M., Benassi, E., Besio, G., Cottalasso, D., Cupello, A., Maffini, M., Mainardi, P., Pronzato, M. A., and Scotto, P. A. Phosphatidylserine increases in vivo the synaptosomal uptake of exogenous GABA in rats. Exp.Neurol. 1988;99(2):4 PubMed
  10. Melis, G. B., Paoletti, A. M., Mais, V., and Fioretti, P. Interference of dopamine infusion on gamma-amino butyric acid (GABA)-stimulated prolactin increase. J.Endocrinol.Invest 1980;3(4):445-448.
  11. Boonstra E, de Kleijn R, Colzato LS, Alkemade A, Forstmann BU, Nieuwenhuis S. Neurotransmitters as food supplements: the effects of GABA on brain and behavior. Front Psychol. 2015 Oct 6;6:1520. doi: 10.3389/fpsyg.2015.01520. eCollection 2015. PubMed
  12. de Bie TH, Witkamp RF, Balvers MG, Jongsma MA. Effects of ?-aminobutyric acid supplementation on glucose control in adults with prediabetes: A double-blind, randomized, placebo-controlled trial. Am J Clin Nutr 2023;118(3):708-719. PubMed

See these in context on the Gamma-aminobutyric Acid (gaba) monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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