Garlic 1000 mg Gummies Natural Grape Flavor Ingredients & Drug Interactions
by Lifeable
What is this page for?
First and foremost: checking Garlic 1000 mg Gummies Natural Grape Flavor against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Garlic 1000 mg Gummies Natural Grape Flavor is a dietary supplement by Lifeable with 2 active ingredients. Its ingredients are commonly taken for replacing fluids and electrolytes, preventing dehydration during exercise or illness, treating low blood sodium (under medical care).Based on those ingredients, 1,007 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Black Garlic Bulb Extract, Sodium. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Garlic 1000 mg Gummies Natural Grape Flavor by Lifeable
Ask about any prescription or over-the-counter medication and we check it for interactions with Garlic 1000 mg Gummies Natural Grape Flavor by Lifeable — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Garlic 1000 mg Gummies Natural Grape Flavor by Lifeable
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product has two active ingredients: sodium and black garlic bulb extract. Sodium is an electrolyte your body needs in small amounts for nerve and muscle function, though the facts note it's essential to avoid excess intake.
Black garlic bulb extract is a concentrated form of garlic, which has traditionally been used to support various aspects of cardiovascular and metabolic health. The gummies also contain several inactive ingredients — glucose syrup, sugar, pectin, citric acid, black carrot concentrate, chlorophyll, and carnauba wax — that serve as sweeteners, thickeners, colors, and coatings.
Does it work?
Moderate evidence
For black garlic bulb extract, the research we hold suggests it is possibly effective for periodontitis (gum disease), nonalcoholic fatty liver disease, diabetes, hypertension (high blood pressure), and atherosclerosis (artery hardening). For sodium itself, the evidence shows it is likely effective for cystic fibrosis and possibly effective for amphotericin B nephrotoxicity (a drug's kidney damage); however, sodium's role in this product as a supplement ingredient is not the same as its established uses in those conditions.
How safe is it?
Well-documented data
Black garlic bulb extract is generally well tolerated when taken orally. The most common side effects are mild — abdominal pain, body odor, flatulence, bad breath, and nausea.
A small number of people may have allergic reactions, and there are rare case reports of increased bleeding risk. Sodium is well tolerated when you stay within normal dietary amounts, but too much sodium is linked to high blood pressure, worsened heart disease, and kidney strain.
The product's safety notes advise against sodium supplements or very high intake without medical guidance. For pregnancy and lactation, sodium is rated likely safe, but black garlic data on pregnancy and lactation isn't on file, so you'd need to talk with your doctor or pharmacist for personalized advice.
Meds to double-check
Moderate interaction found
Check your medications if you take lithium (sodium can alter its levels dangerously), blood pressure medications (both ingredients may lower pressure further), blood thinners or anticoagulants like warfarin (garlic may increase bleeding), diabetes medications (garlic may lower blood sugar further), corticosteroids, protease inhibitors, tacrolimus, or any drugs your liver metabolizes heavily. These are Moderate-severity interactions; use the medication checker below with your full list.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
These gummies may appeal to someone looking for garlic's traditional health benefits in an easy-to-take form. However, if you take lithium, blood pressure medications, blood thinners, diabetes drugs, or any medication metabolized by your liver, you should check your exact medications with the tool on this page before starting.
Also speak with your pharmacist or doctor if you're pregnant, breastfeeding, or have heart, kidney, or blood pressure concerns.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 24, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Garlic 1000 mg Gummies Natural Grape Flavor, straight from the product label.
| Brand | Lifeable |
|---|---|
| Barcode (UPC) | 850023062796 |
| Net contents | 60 Gummy(ies) |
| Market status | On market |
| Date entered into DSLD | Jul 24, 2025 |
| DSLD ID | 333129 |
| Product type | Botanical |
| Supplement form | Gummy Or Jelly |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Children 4 or More Years of Age, Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Garlic 1000 mg Gummies Natural Grape Flavor by Lifeable, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Calories | 20 Calorie(s) | -- |
| Total Carbohydrates | 5 Gram(s) | 2% |
| Sodium | 5 mg | 1% |
| Added Sugars | 3 Gram(s) | 6% |
| Total Sugars | 3 Gram(s) | -- |
| Black Garlic Bulb Extract | 100 mg | -- |
Other ingredients: Glucose Syrup, Sugar, Water, Pectin, Citric Acid, Black Carrot Concentrate, Chlorophyll, Trisodium Citrate, Natural Flavors, Carnauba Wax
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
Don't sacrifice great taste for great health. Lifeable gummy vitamins and supplements are bursting with nutrients and fruit flavors so you will actually enjoy taking them. Lifeable - Health gone tasty!
Suggested/Recommended/Usage/Directions
Suggested use: As a dietary supplement, take two (2) gummies per day. Chew thoroughly before swallowing.
Precautions
Do not exceed suggested serving size. Do not use this product if safety seal under cap is torn or missing.
If you have a medical condition, are taking medication, or are pregnant or nursing, ask a doctor before using.
Not for children under 2 years of age due to risk of choking. Child resistant cap Keep out of reach of children
Storage
Store at room temperature. Avoid excessive heat.
Formulation
Product of Israel Packaged in the USA The benefits of Garlic in a delicious gummy! Cardiovascular health
Vegan
Gluten free Nut free
Does not contain eggs, wheat (gluten), milk, peanuts, tree nuts, sesame, soy or shellfish. Processed in a nut free facility.
Seals/Symbols
Vegan OU (Kosher)
Formula
OU (Kosher)
FDA Statement of Identity
Dietary Supplement
FDA Disclaimer Statement
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Garlic 1000 mg Gummies Natural Grape Flavor by Lifeable label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Garlic 1000 mg Gummies Natural Grape Flavor by Lifeable
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Gummy(ies) Dosage formGummy Or Jelly Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Sodium
Interacts with205 drugs
Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets g...
Sodium monograph & interactionsBlack Garlic Bulb Extract
Interacts with989 drugs
Garlic is a common food and supplement that may modestly help with blood pressure and cholesterol, though the evidence is mixed and effects are usuall...
Black Garlic Bulb Extract monograph & interactionsOther (inactive) ingredients: Glucose Syrup, Sugar, Water, Pectin, Citric Acid, Black Carrot Concentrate, Chlorophyll, Trisodium Citrate, Natural Flavors, Carnauba Wax. These complete the product’s ingredient list but are not active constituents.
Garlic 1000 mg Gummies Natural Grape Flavor by Lifeable Drug Interactions
HelloPharmacist Interaction Report
Lifeable's Garlic 1000 mg Gummies contain sodium and black garlic bulb extract, both of which interact with medications.
The most serious concern involves sodium's interaction with lithium — high sodium intake can reduce lithium levels and effectiveness, while low sodium intake can raise them to toxic levels, so anyone on lithium needs to be very careful with sodium supplements.
Read the full breakdown — every affected drug type, severity by severity
Sodium also interacts with blood pressure medications (antihypertensive drugs), corticosteroids, didanosine, sodium phosphates, tolvaptan, and other sodium-containing drugs — all at Moderate severity. High sodium can blunt blood pressure control and increase the risk of dangerously high sodium levels (hypernatremia) in your blood.
Black garlic bulb extract carries Moderate interactions with blood pressure medications (may lower blood pressure further), blood thinners and anticoagulants (may increase bleeding risk), diabetes medications (may lower blood sugar further), and certain enzyme-metabolized drugs including protease inhibitors, CYP3A4 substrates, CYP2E1 substrates, warfarin, and tacrolimus. Altogether, these interactions span 995 individual medications.
Use the medication checker below to look up your exact drugs before starting these gummies.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Garlic 1000 mg Gummies Natural Grape Flavor?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Garlic 1000 mg Gummies Natural Grape Flavor interact with 1,007 drugs. Click any drug to see the details.
2 of the 2 ingredients in Garlic 1000 mg Gummies Natural Grape Flavor interact with drugs. Each result below shows which ingredient is responsible. Black Garlic Bulb Extract Sodium
Ado-trastuzumab EmtansineKadcyla
How Ado-trastuzumab Emtansine interacts with Garlic 1000 mg Gummies Natural Grape Flavor — through 1 ingredient. Tap an ingredient for the detail:
Black Garlic Bulb ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, garlic products containing allicin might induce intestinal CYP3A4 and inhibit hepatic CYP3A4.
Read the full Black Garlic Bulb Extract + Ado-trastuzumab Emtansine interactionAbciximabReoPro
How Abciximab interacts with Garlic 1000 mg Gummies Natural Grape Flavor — through 1 ingredient. Tap an ingredient for the detail:
Black Garlic Bulb ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Garlic may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Black Garlic Bulb Extract + Abciximab interactionAbemaciclibVerzenio
How Abemaciclib interacts with Garlic 1000 mg Gummies Natural Grape Flavor — through 1 ingredient. Tap an ingredient for the detail:
Black Garlic Bulb ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, garlic products containing allicin might induce intestinal CYP3A4 and inhibit hepatic CYP3A4.
Read the full Black Garlic Bulb Extract + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Garlic 1000 mg Gummies Natural Grape Flavor — through 1 ingredient. Tap an ingredient for the detail:
Black Garlic Bulb ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, garlic products containing allicin might induce intestinal CYP3A4 and inhibit hepatic CYP3A4.
Read the full Black Garlic Bulb Extract + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Garlic 1000 mg Gummies Natural Grape Flavor — through 1 ingredient. Tap an ingredient for the detail:
Black Garlic Bulb ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, garlic products containing allicin might induce intestinal CYP3A4 and inhibit hepatic CYP3A4.
Read the full Black Garlic Bulb Extract + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Garlic 1000 mg Gummies Natural Grape Flavor — through 1 ingredient. Tap an ingredient for the detail:
Black Garlic Bulb ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Garlic may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Black Garlic Bulb Extract + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Garlic 1000 mg Gummies Natural Grape Flavor — through 1 ingredient. Tap an ingredient for the detail:
Black Garlic Bulb ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, garlic products containing allicin might induce intestinal CYP3A4 and inhibit hepatic CYP3A4.
Read the full Black Garlic Bulb Extract + Acalabrutinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Garlic 1000 mg Gummies Natural Grape Flavor — through 1 ingredient. Tap an ingredient for the detail:
Black Garlic Bulb ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking garlic with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Black Garlic Bulb Extract + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Garlic 1000 mg Gummies Natural Grape Flavor — through 2 ingredients. Tap an ingredient for the detail:
SodiumAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
Read the full Sodium + Acebutolol interactionBlack Garlic Bulb ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking garlic with antihypertensive drugs might increase the risk of hypotension.
Read the full Black Garlic Bulb Extract + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Garlic 1000 mg Gummies Natural Grape Flavor — through 1 ingredient. Tap an ingredient for the detail:
Black Garlic Bulb ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Garlic may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Black Garlic Bulb Extract + Acenocoumarol interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Garlic 1000 mg Gummies Natural Grape Flavor — through 1 ingredient. Tap an ingredient for the detail:
Black Garlic Bulb ExtractCytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Garlic might increase levels of drugs metabolized by CYP2E1.
Read the full Black Garlic Bulb Extract + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Garlic 1000 mg Gummies Natural Grape Flavor — through 1 ingredient. Tap an ingredient for the detail:
Black Garlic Bulb ExtractCytochrome P450 2e1 (cyp2e1) Substrates, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Garlic might increase levels of drugs metabolized by CYP2E1.
Read the full Black Garlic Bulb Extract + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Garlic 1000 mg Gummies Natural Grape Flavor — through 1 ingredient. Tap an ingredient for the detail:
Black Garlic Bulb ExtractAnticoagulant/antiplatelet Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Garlic may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Black Garlic Bulb Extract + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Garlic 1000 mg Gummies Natural Grape Flavor — through 1 ingredient. Tap an ingredient for the detail:
Black Garlic Bulb ExtractCytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Garlic might increase levels of drugs metabolized by CYP2E1.
Read the full Black Garlic Bulb Extract + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Garlic 1000 mg Gummies Natural Grape Flavor — through 1 ingredient. Tap an ingredient for the detail:
Black Garlic Bulb ExtractCytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Garlic might increase levels of drugs metabolized by CYP2E1.
Read the full Black Garlic Bulb Extract + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Garlic 1000 mg Gummies Natural Grape Flavor — through 1 ingredient. Tap an ingredient for the detail:
Black Garlic Bulb ExtractCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Garlic might increase levels of drugs metabolized by CYP2E1.
Read the full Black Garlic Bulb Extract + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Garlic 1000 mg Gummies Natural Grape Flavor — through 1 ingredient. Tap an ingredient for the detail:
Black Garlic Bulb ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, garlic products containing allicin might induce intestinal CYP3A4 and inhibit hepatic CYP3A4.
Read the full Black Garlic Bulb Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Garlic 1000 mg Gummies Natural Grape Flavor — through 1 ingredient. Tap an ingredient for the detail:
Black Garlic Bulb ExtractCytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Garlic might increase levels of drugs metabolized by CYP2E1.
Read the full Black Garlic Bulb Extract + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Garlic 1000 mg Gummies Natural Grape Flavor — through 1 ingredient. Tap an ingredient for the detail:
Black Garlic Bulb ExtractCytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Garlic might increase levels of drugs metabolized by CYP2E1.
Read the full Black Garlic Bulb Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Garlic 1000 mg Gummies Natural Grape Flavor — through 1 ingredient. Tap an ingredient for the detail:
Black Garlic Bulb ExtractCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Garlic might increase levels of drugs metabolized by CYP2E1.
Read the full Black Garlic Bulb Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Garlic 1000 mg Gummies Natural Grape Flavor — through 1 ingredient. Tap an ingredient for the detail:
Black Garlic Bulb ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, garlic products containing allicin might induce intestinal CYP3A4 and inhibit hepatic CYP3A4.
Read the full Black Garlic Bulb Extract + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Garlic 1000 mg Gummies Natural Grape Flavor — through 1 ingredient. Tap an ingredient for the detail:
Black Garlic Bulb ExtractCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Garlic might increase levels of drugs metabolized by CYP2E1.
Read the full Black Garlic Bulb Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Garlic 1000 mg Gummies Natural Grape Flavor — through 1 ingredient. Tap an ingredient for the detail:
Black Garlic Bulb ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, garlic products containing allicin might induce intestinal CYP3A4 and inhibit hepatic CYP3A4.
Read the full Black Garlic Bulb Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Garlic 1000 mg Gummies Natural Grape Flavor — through 1 ingredient. Tap an ingredient for the detail:
Black Garlic Bulb ExtractCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Garlic might increase levels of drugs metabolized by CYP2E1.
Read the full Black Garlic Bulb Extract + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Garlic 1000 mg Gummies Natural Grape Flavor — through 1 ingredient. Tap an ingredient for the detail:
Black Garlic Bulb ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, garlic products containing allicin might induce intestinal CYP3A4 and inhibit hepatic CYP3A4.
Read the full Black Garlic Bulb Extract + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Garlic 1000 mg Gummies Natural Grape Flavor — through 1 ingredient. Tap an ingredient for the detail:
Black Garlic Bulb ExtractCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Garlic might increase levels of drugs metabolized by CYP2E1.
Read the full Black Garlic Bulb Extract + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Garlic 1000 mg Gummies Natural Grape Flavor — through 1 ingredient. Tap an ingredient for the detail:
Black Garlic Bulb ExtractCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Garlic might increase levels of drugs metabolized by CYP2E1.
Read the full Black Garlic Bulb Extract + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Garlic 1000 mg Gummies Natural Grape Flavor — through 1 ingredient. Tap an ingredient for the detail:
Black Garlic Bulb ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, garlic products containing allicin might induce intestinal CYP3A4 and inhibit hepatic CYP3A4.
Read the full Black Garlic Bulb Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Garlic 1000 mg Gummies Natural Grape Flavor — through 1 ingredient. Tap an ingredient for the detail:
Black Garlic Bulb ExtractCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Garlic might increase levels of drugs metabolized by CYP2E1.
Read the full Black Garlic Bulb Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Garlic 1000 mg Gummies Natural Grape Flavor — through 1 ingredient. Tap an ingredient for the detail:
Black Garlic Bulb ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, garlic products containing allicin might induce intestinal CYP3A4 and inhibit hepatic CYP3A4.
Read the full Black Garlic Bulb Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Garlic 1000 mg Gummies Natural Grape Flavor with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Black Garlic Bulb Extract
Anticoagulant/Antiplatelet Drugs
Garlic may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Raw garlic and a variety of garlic extracts have antiplatelet activity and can increase prothrombin time.
Antidiabetes Drugs
Theoretically, taking garlic with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research suggests that garlic and garlic extract lower blood glucose levels in healthy and diabetic individuals.
Antihypertensive Drugs
Theoretically, taking garlic with antihypertensive drugs might increase the risk of hypotension.
In human research, both garlic and garlic extracts have blood pressure-lowering effects.
Atazanavir (Reyataz)
Theoretically, garlic might decrease levels and effects of atazanavir.
In a case report, a patient consuming six stir-fried garlic cloves three times weekly developed suboptimal atazanavir levels and increases in HIV viral load. While the exact cause of this interaction is unclear, there is speculation that garlic might decrease the intestinal absorption of atazanavir or increase its metabolism by inducing cytochrome P450 3A4 (CYP3A4). Until more is known, advise patients not to consume large amounts of garlic while taking atazanavir.
Cytochrome P450 2E1 (Cyp2E1) Substrates
Garlic might increase levels of drugs metabolized by CYP2E1.
Clinical research suggests garlic oil can inhibit the activity of CYP2E1 by 39%. Use garlic oil cautiously in patients taking drugs metabolized by these enzymes.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, garlic products containing allicin might induce intestinal CYP3A4 and inhibit hepatic CYP3A4. This may increase or decrease levels of drugs metabolized by CYP3A4.
Some human research suggests that garlic may induce INTESTINAL CYP3A4, reducing levels of drugs metabolized by this enzyme. This is primarily based on a study showing that taking a specific allicin-containing garlic product (GarliPure Maximum Allicin Formula, Natrol Inc.) twice daily for 3 days reduces saquinavir levels by approximately 50%. It is speculated that the allicin constituent induced CYP3A4 in the gut mucosa. Another study shows that giving docetaxel intravenously, bypassing the CYP3A4 enzymes in the gut mucosa, along with the same specific garlic product for 12 consecutive days, does not affect docetaxel levels. Conversely, there is concern that garlic may inhibit HEPATIC CYP3A4. In a single case report, increased tacrolimus levels and liver injury occurred in a liver transplant patient after taking a specific garlic supplement (Garlicin Cardio, Nature's Way) at up to three times the manufacturer recommended dose for 7 days. Several other studies have evaluated the impact of other garlic formulations on CYP3A4 substrates and have found no effect. Most of the products in these studies provided little or no allicin.
Isoniazid
Theoretically, garlic might decrease levels of isoniazid.
Animal research suggests that an aqueous extract of garlic reduces isoniazid levels by about 65%. Garlic reduced the maximum concentration (Cmax) and area under the curve (AUC), but not the half-life, of isoniazid. This suggests that garlic extract might inhibit isoniazid absorption across the intestinal mucosa; however, the exact mechanism of this potential interaction is not known.
Protease Inhibitors (Pis)
Theoretically, garlic products containing allicin might decrease levels of PIs.
Protease inhibitors are metabolized by cytochrome P450 3A4 (CYP3A4) isoenzymes. There is concern that garlic products containing allicin might induce intestinal CYP3A4, reducing plasma levels of protease inhibitors. This is primarily based on a study showing that taking a specific garlic product (GarliPure Maximum Allicin Formula, Natrol Inc.) twice daily for 3 days reduces levels of saquinavir, a PI, by approximately 50%. It is speculated that the allicin constituent induce CYP3A4 in the gut mucosa. Several studies have evaluated the impact of other garlic formulations on CYP3A4 substrates and have found no effect. Most of the products in these studies provided little or no allicin.
Saquinavir (Fortovase, Invirase)
Theoretically, garlic containing allicin might decrease levels of saquinavir.
Saquinavir is a substrate of cytochrome P450 3A4 (CYP3A4) isoenzymes. There is concern that garlic products containing allicin might induce intestinal CYP3A4 and cause subtherapeutic levels of saquinavir. This is primarily based on a pharmacokinetic study showing that taking a specific garlic product (GarliPure Maximum Allicin Formula, Natrol Inc.) twice daily for 3 days reduces saquinavir levels by approximately 50%. It is speculated that the allicin constituent induces CYP3A4 in the gut mucosa. Several pharmacokinetic studies have evaluated the impact of other garlic formulations on CYP3A4 substrates and have found no effect. Most of the products in these studies provided little or no allicin. Until more is known about this potential interaction, use garlic containing allicin cautiously in patients taking saquinavir.
Sofosbuvir (Sovaldi)
Theoretically, taking garlic with sofosbuvir might decrease its effectiveness.
Animal research in rats shows that giving aged garlic extract 120 mg/kg orally daily for 14 days decreases the area under the concentration time curve (AUC) after a single sofosbuvir dose of 40 mg/kg by 36%, increases the clearance by 63%, and decreases the plasma concentrations at 1 and 8 hours by 35% and 58%, respectively. This interaction is hypothesized to be due to induction of intestinal P-glycoprotein expression by garlic.
Tacrolimus (Prograf)
Theoretically, garlic might increase levels of tacrolimus.
In one case report, a liver transplant patient taking tacrolimus experienced increased tacrolimus levels and liver injury after taking a specific garlic supplement (Garlicin Cardio, Nature's Way) at up to three times the manufacturer recommended dose for 7 days. It is speculated that garlic inhibited hepatic cytochrome P450 3A4 (CYP3A4), which increased plasma levels of tacrolimus.
Warfarin (Coumadin)
Theoretically, garlic might increase the risk of bleeding with warfarin.
Raw garlic and a variety of garlic extracts have antiplatelet activity and can increase prothrombin time. In addition, there is a report of two patients who experienced an increase in a previously stabilized international normalized ratio (INR) with concomitant garlic and warfarin use. However, this report has been subsequently debated due to limited clinical information. Other clinical studies have not identified an effect of garlic on INR, warfarin pharmacokinetics, or bleeding risk. More evidence is needed to determine the safety of using garlic with warfarin.
Sodium
Antihypertensive Drugs
Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
High intake of dietary sodium can increase systolic and diastolic blood pressure. Also, high intake of sodium may necessitate increased use of antihypertensive medications to achieve blood pressure control in some patients, such as those with chronic kidney disease.
Corticosteroids
Concomitant use of mineralocorticoids and some glucocorticoids with sodium supplements might increase the risk of hypernatremia.
Mineralocorticoids and some glucocorticoids (corticosteroids) cause sodium retention. This effect is dose-related and depends on mineralocorticoid potency. It is most common with hydrocortisone, cortisone, and fludrocortisone, followed by prednisone and prednisolone.
Didanosine (Videx)
Concomitant use of didanosine with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia.
Didanosine formulations contain a significant amount of sodium.
Lithium
Altering dietary intake of sodium might alter the levels and clinical effects of lithium.
High sodium intake can reduce plasma concentrations of lithium by increasing lithium excretion. Reducing sodium intake can significantly increase plasma concentrations of lithium and cause lithium toxicity in patients being treated with lithium carbonate. Stabilizing sodium intake is shown to reduce the percentage of patients with lithium level fluctuations above 0.8 mEq/L. Patients taking lithium should avoid significant alterations in their dietary intake of sodium.
Sodium Phosphates
Theoretically, concomitant use of sodium phosphate with sodium supplements might increase the risk of hypernatremia.
Use of high doses (> 45 mL in 24 hours) of sodium phosphate, such as those used for bowel cleansing before surgery, can lead to serious electrolyte disturbances, including hypernatremia. The risk of hypernatremia is highest in the elderly and people with other risk factors for electrolyte disturbances.
Sodium-Containing Drugs
Concomitant use of sodium-containing drugs with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia and long-term sodium-related complications.
The Chronic Disease Risk Reduction (CDRR) intake level of 2.3 grams of sodium daily indicates the intake at which it is believed that chronic disease risk increases for the apparently healthy population. Some medications contain high quantities of sodium. When used in conjunction with sodium supplements or high-sodium diets, the CDRR may be exceeded. Additionally, concomitant use may increase the risk for hypernatremia; this risk is highest in the elderly and people with other risk factors for electrolyte disturbances.
Tolvaptan (Samsca)
Theoretically, concomitant use of tolvaptan with sodium might increase the risk of hypernatremia.
Tolvaptan is a vasopressin receptor 2 antagonist that is used to increase sodium levels in patients with hyponatremia. Patients taking tolvaptan should use caution with the use of sodium salts such as sodium chloride.
Brand information
Manufacturer and brand details for Garlic 1000 mg Gummies Natural Grape Flavor, from the product label.
Lifeable
See all Lifeable products- Name
- Lifeable
- City
- Brooklyn
- State
- NY
- ZipCode
- 11204
- Phone Number
- 1-855-889-6757
- Web Address
- www.lifeable.com
Garlic 1000 mg Gummies Natural Grape Flavor by Lifeable: Common Questions
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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The Full Monographs Behind Garlic 1000 mg Gummies Natural Grape Flavor’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sodium
Interacts with 205 drugsSodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets get more than enough—often too much—from...
Read the full Sodium monograph → Herb & supplement monographGarlic
Interacts with 989 drugsGarlic is a common food and supplement that may modestly help with blood pressure and cholesterol, though the evidence is mixed and effects are usually small. It is generally safe in food am...
Read the full Garlic monograph →Sources & How We Checked
Garlic 1000 mg Gummies Natural Grape Flavor's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 192 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Sodium 38 references
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Garlic 154 references
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