No known drug interactions for the matched ingredients — not a guarantee none exist. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Germanium Ingredients & Drug Interactions

by Angstrom Minerals

Liquid Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

Germanium is a dietary supplement by Angstrom Minerals with 2 active ingredients. Its ingredients are commonly taken for immune support, cancer (unproven, alternative therapy), antioxidant claims.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Germanium by Angstrom Minerals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 2 active ingredients.

This product contains 2 ingredients: 99.9% pure germanium and high energy water. Germanium is a mineral element that some marketers claim supports immune function and overall wellness, but evidence for these uses is insufficient.

We hold no data on high energy water.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Germanium product and its label doesn't state a use — see Germanium's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence we hold doesn't establish that germanium works for cancer, hepatitis B, or other claimed uses — the data rates all of these as having insufficient reliable evidence. No other effectiveness claims are covered in the data.

The evidence, ingredient by ingredient Germanium

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Germanium supplements are rated likely unsafe in pregnancy and lactation. More broadly, the safety data advises against germanium supplements entirely: they have caused serious kidney damage (renal tubular cell damage and renal failure), liver damage (hepatic steatosis), anemia, nerve damage (peripheral neuropathy), spinal cord degeneration, muscle damage, and deaths — sometimes at doses that seemed reasonable.

More than 30 cases of severe harm or death have been reported. Germanium from dietary sources (0.4 to 3.4 mg daily) is generally well tolerated, but supplement doses carry real risk.

Side effects, ingredient by ingredient Germanium

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No medication interactions are documented for the ingredients we could check. However, the germanium in this product carries serious safety risks independent of any drug interaction.

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. No medication interactions are currently documented, and safety information is well characterized.

The safety data is clear: germanium supplements should be avoided due to toxicity risk. The product has no documented drug interactions, but that doesn't make it safe — the harm comes from the germanium itself, not from how it mixes with your medications.

Talk with your doctor or pharmacist before considering it or any germanium supplement.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 31, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Germanium, straight from the product label.

Brand Angstrom Minerals
Net contents 12 Fluid Ounce(s)
Market status On market
Date entered into DSLD Aug 31, 2018
DSLD ID 180344
Product type Non-nutrient/non-botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Children (All)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Germanium by Angstrom Minerals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Not Present
Maximum serving Sizes:
1 Not Present
IngredientAmount% DV
high energy Water0 NP--
99.9% pure Germanium0 NP--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Leading experts have agreed on the fact that many diseases, and often even death, are caused by mineral deficiencies. According to Senate Document #264, 99% of Americans suffer from mineral imbalances. Our physical well-being is directly dependent upon the minerals we consume. Nature's most digestible source of pure minerals Angstrom is a unit used in measuring the length of light waves. Angstrom minerals are in the purest form and are one hundred million times smaller than colloidal minerals making them the most digestible source of minerals available today. The average absorption rate for most of the minerals on the market (colloidal, ionic, etc.) in adults is approximately 10% and even less if digestive problems are present. All of the Angstrom Minerals penetrate to the DNA which means they can cross the blood/brain barrier to supply energy directly to the brain. What's unique about these minerals is the fact they are totally water soluble - which simply means what the body doesn't need it will excrete! Due to the purity and concentration of this product, it has no expiration date.

Minor crystallization may occur, but this does not affect the quality of this product. Expect consistency of result with the Angstrom Minerals

"Improves Cellular Oxygenation"

It's your health It's your choice Choose wisely!! Used for over 50 years in Europe The product of choice Angstrom Minerals Call us to discuss your individual protocol, mineral supplementation and directions. Guaranteed results

Formulation

The minerals are naturally preserved, contain no bacteria and do not lose potency over time.

FDA Disclaimer Statement

Disclaimer: These statements have not been evaluated by the Food and Drug Administration. These statements and the products of this company are not intended to diagnose, treat, cure or prevent any disease.

Precautions

Consult your physician before taking this product.

Angstrom Minerals are not known to interfere with medications or herbal remedies.

Before beginning any new dietary supplementation program, always inform your consulted physician.

Formula

Germanium 50 parts per million

Suggested/Recommended/Usage/Directions

Suggested Dosage: Adults & children 60 pounds & up - 1 teaspoon in the morning. Children 30-60 pounds: 1/2 of adult dosage Children 10-30 pounds: 1/8 of adult dosage These are maintenance dosages. You may need to begin your program at a higher dosage. Before beginning any new dietary supplementation program, always inform your consulted physician.

See for yourself

Germanium by Angstrom Minerals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Germanium by Angstrom Minerals

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Not Present Dosage formLiquid Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

High energy Water

0 NP per serving

99.9% pure Germanium

No known
interactions
0 NP per serving

Germanium is a chemical element sometimes sold as a dietary supplement, but there is no reliable evidence it treats any disease. More importantly, ger...

99.9% pure Germanium monograph & interactions
Interaction report

Germanium by Angstrom Minerals Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Germanium. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Germanium, from the product label.

Angstrom Minerals

See all Angstrom Minerals products
Name
Dr. LaMar's Products Co., Inc.
City
Emporia
State
KS
ZipCode
66801
Phone Number
800-941-2889
Web Address
www.drlamarsproducts.com
Pharmacist Counseling Corner

Germanium by Angstrom Minerals: Common Questions

Does Germanium by Angstrom Minerals interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Germanium. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Germanium contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is germanium safe to take?
No. The safety data advises against germanium supplements due to toxicity risk. More than 30 cases of serious kidney damage, liver damage, nerve damage, spinal cord degeneration, and death have been reported — sometimes at doses people believed were safe. Talk with your doctor or pharmacist before considering any germanium supplement.
Can I take this if I'm pregnant or breastfeeding?
No. Germanium is rated likely unsafe during pregnancy and lactation. If you're pregnant, planning pregnancy, or breastfeeding, talk with your doctor or pharmacist before taking any germanium product.
Does germanium work for cancer or hepatitis B?
The evidence we hold doesn't establish that germanium works for either condition. Both are rated as having insufficient reliable evidence, which means claims about germanium for these uses aren't backed by solid data.
What are the side effects of germanium?
At dietary levels (0.4 to 3.4 mg daily), germanium is generally well tolerated. But supplements have caused kidney damage and kidney failure, liver damage, anemia, nerve damage, muscle damage, spinal cord degeneration, and deaths — even in people who took what seemed like reasonable doses.
Does this interact with my medications?
No documented interactions are recorded for germanium. However, that's not why you should be cautious about this product — the real concern is the safety risk from germanium itself, not how it mixes with your drugs.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Germanium is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Germanium label
Go deeper

The Full Monographs Behind Germanium’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Germanium's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 30 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Germanium 30 references
  1. Tao SH, Bolger, PM. Hazard assessment of germanium supplements. Regul Toxicol Pharmacol 1997;25:211-9.
  2. Budman DR, Schulman P, Vinciguerra V, Degnan TJ. Phase I trial of spirogermanium given by infusion in a multiple-dose schedule. Cancer Treat Rep 1982;66:173-5..
  3. Mainwaring MG, Poor C, Zander DS, Harman E. Complete remission of pulmonary spindle cell carcinoma after treatment with oral germanium sesquioxide. Chest 2000;117:591-3.. PubMed
  4. Vogelzang NJ, Gesme DH, Kennedy BJ. A phase II study of spirogermanium in advanced human malignancy. Am J Clin Oncol 1985;8:341-4.. PubMed
  5. Ettinger DS, Finkelstein DM, Donehower RC, et al. Phase II study of N-methylformamide, spirogermanium, and 4-demethoxydaunorubicin in the treatment of non-small cell lung cancer (EST 3583): an Eastern Cooperative Oncology Group study. Med Pediatr Oncol 1 PubMed
  6. Higuchi I, Izumo S, Kuriyama M, et al. Germanium myopathy: clinical and experimental pathological studies. Acta Neuropathol (Berl) 1989;79:300-4.. PubMed
  7. Matsusaka T, Fujii M, Nakano T, et al. Germanium-induced nephropathy: report of two cases and review of the literature. Clin Nephrol 1988;30:341-5..
  8. Hess B, Raisin J, Zimmermann A, et al. Tubulointerstitial nephropathy persisting 20 months after discontinuation of chronic intake of germanium lactate citrate. Am J Kidney Dis 1993;21:548-52.. PubMed
  9. Luck BE, Mann H, Melzer H, et al. Renal and other organ failure caused by germanium intoxication. Nephrol Dial Transplant 1999;14:2464-8. PubMed
  10. Schauss AG. Nephrotoxicity and neurotoxicity in humans from organogermanium compounds and germanium dioxide. Biol Trace Elem Res 1991;29:267-80.. PubMed
  11. Schein PS, Slavik M, Smythe T, et al. Phase I clinical trial of spirogermanium. Cancer Treat Rep 1980;64:1051-6..
  12. Trope C, Mattsson W, Gynning I, et al. Phase II study of spirogermanium in advanced ovarian malignancy. Cancer Treat Rep 1981;65:119-20..
  13. Gerber GB, Leonard A. Mutagenicity, carcinogenicity and teratogenicity of germanium compounds. Mutat Res 1997;387:141-6.. PubMed
  14. Asaka T, Nitta E, Makifuchi T, et al. Germanium intoxication with sensory ataxia. J Neurol Sci 1995;130:220-3.. PubMed
  15. Sanai T, Okuda S, Onoyama K, et al. Germanium dioxide-induced nephropathy: a new type of renal disease. Nephron. 1990;54:53-60.. PubMed
  16. Krapf R, Schaffner T, Iten PX. Abuse of germanium associated with fatal lactic acidosis. Nephron 1992;62:351-6.. PubMed
  17. Takeuchi A, Yoshizawa N, Oshima S, et al. Nephrotoxicity of germanium compounds: report of a case and review of the literature. Nephron 1992;60:436-42.. PubMed
  18. Luck, B. E., Mann, H., Melzer, H., Dunemann, L., and Begerow, J. Renal and other organ failure caused by germanium intoxication. Nephrol.Dial.Transplant. 1999;14(10):2464-2468. PubMed
  19. Hirayama, C., Suzuki, H., Ito, M., Okumura, M., and Oda, T. Propagermanium: a nonspecific immune modulator for chronic hepatitis B. J Gastroenterol. 2003;38(6):525-532. PubMed
  20. Tsutsumi, Y., Tanaka, J., Kanamori, H., Musashi, M., Minami, H., Fukushima, A., Yamato, H., Ehira, N., Kawamura, T., Obara, S., Ogura, N., Asaka, M., Imamura, M., and Masauzi, N. Effectiveness of propagermanium treatment in multiple myeloma patients. Eur. PubMed
  21. Fujimoto, M., Ishibashi, H., Shimamura, R., Takahashi, K., Hirata, Y., Kudo, J., Niho, Y., Kira, J., and Miyata, K. [A patient with liver cirrhosis manifesting various symptoms including cerebellar ataxia due to germanium intoxication]. Fukuoka Igaku Zass
  22. Raisin, J., Hess, B., Blatter, M., Zimmermann, A., Descoeudres, C., Horber, F. F., and Jaeger, P. [Toxicity of an organic Germanium compound: deleterious consequences of a "natural remedy"]. Schweiz.Med.Wochenschr. 1-8-1992;122(1-2):11-13.
  23. Kamijo, M., Yagihashi, S., Kida, K., Narita, S., and Nakata, F. [An autopsy case of chronic germanium intoxication presenting peripheral neuropathy, spinal ataxia, and chronic renal failure]. Rinsho Shinkeigaku 1991;31(2):191-196.
  24. Obara, K., Saito, T., Sato, H., Yamakage, K., Watanabe, T., Kakizawa, M., Tsukamoto, T., Kobayashi, K., Hongo, M., and Yoshinaga, K. Germanium poisoning: clinical symptoms and renal damage caused by long-term intake of germanium. Jpn.J.Med. 1991;30(1):67- PubMed
  25. Van der Spoel, J. I., Stricker, B. H., Schipper, M. E., de Bruijn, W., de Smet, P. A., and Esseveld, M. R. [Toxic damage of kidney, liver and muscle attributed to the administration of germanium-lactate-citrate]. Ned.Tijdschr.Geneeskd. 6-22-1991;135(25):1
  26. Schauss, A. G. Nephrotoxicity in humans by the ultratrace element germanium. Ren Fail. 1991;13(1):1-4. PubMed
  27. Iijima, M., Mugishima, M., Takeuchi, M., Uchiyama, S., Kobayashi, I., and Maruyama, S. [A case of inorganic germanium poisoning with peripheral and cranial neuropathy, myopathy and autonomic dysfunction]. No To Shinkei 1990;42(9):851-856.
  28. Nagata, N., Yoneyama, T., Yanagida, K., Ushio, K., Yanagihara, S., Matsubara, O., and Eishi, Y. Accumulation of germanium in the tissues of a long-term user of germanium preparation died of acute renal failure. J.Toxicol.Sci. 1985;10(4):333-341. PubMed
  29. Woolley, P. V., Ahlgren, J. D., Byrne, P. J., Priego, V. M., and Schein, P. S. A Phase I trial of spirogermanium administered on a continuous infusion schedule. Invest New Drugs 1984;2(3):305-309. PubMed
  30. Wang L, Zheng C, Zhao D. Successful management of germanium poisoning-induced multiple organ dysfunctions by combined blood purification therapy. Curr Med Res Opin. 2020 Apr;36(4):687-691. PubMed

See these in context on the Germanium monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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