Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

GI Renew (Normal - 1) Glycerin Ingredients & Drug Interactions

by Dr. Morse's Cellular Botanicals

GI Renew (Normal - 1) Glycerin label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking GI Renew (Normal - 1) Glycerin against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

GI Renew (Normal - 1) Glycerin is a dietary supplement by Dr. Morse's Cellular Botanicals with 8 active ingredients. Its ingredients are commonly taken for cough and chest congestion, sore throat, bronchitis and respiratory irritation.Based on those ingredients, 2,098 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Marshmallow, Plantain, Slippery Elm. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against GI Renew (Normal - 1) Glycerin by Dr. Morse's Cellular Botanicals

Ask about any prescription or over-the-counter medication and we check it for interactions with GI Renew (Normal - 1) Glycerin by Dr. Morse's Cellular Botanicals — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of GI Renew (Normal - 1) Glycerin by Dr. Morse's Cellular Botanicals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 30, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 8 active ingredients.
  • “Proprietary Blend” is a proprietary blend — the label gives one combined amount (1.60 mL) without saying how much of each component you get.

GI Renew is a liquid herbal blend with 8 ingredients: a proprietary mix of mullein, slippery elm, marshmallow, fennel, wild yam, gentian, plantain, and chickweed, plus glycerin, raw honey, water, and alcohol. The active botanicals are traditionally used for digestive support, though the evidence for most of them is limited or not yet established.

Mullein and plantain are included for respiratory and digestive tract function, while marshmallow and slippery elm contain soothing mucilage compounds. The blend also contains fennel for digestive comfort, wild yam and gentian for digestive wellness, and chickweed as a supporting ingredient.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: support cellular regeneration and GI health.
  • We looked for evidence on: Bronchitis, Cough, Constipation, Diarrhea, Dyspepsia, Flatulence — and 4 related terms.
  • The strongest evidence on file: Black Psyllium is rated "Effective" for Constipation (Natural Medicines).
  • Also on file: Black Psyllium is rated "Insufficient Reliable Evidence To Rate" for Diarrhea.
  • Also on file: Fennel is rated "Insufficient Reliable Evidence To Rate" for Bronchitis, Constipation, Cough, Dyspepsia, and more.

The evidence for most ingredients in this blend is not yet firmly established. Fennel is possibly effective for period pain (dysmenorrhea), and plantain is effective for constipation and likely effective for heart disease prevention.

For the other ingredients—mullein, slippery elm, marshmallow, wild yam, gentian, and chickweed—we hold insufficient reliable evidence to rate how well they work for any of the conditions they're traditionally used for. Because this is a blend rather than a single-ingredient supplement, we cannot tell you the dose of each component or how that affects its potential benefit.

The evidence, ingredient by ingredient Mullein Slippery Elm Marshmallow Fennel Wild Yam Gentian Black Psyllium Chickweed

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 7 of the 8 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 8 of 8.
  • General safety write-ups exist for 8 of 8.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Most ingredients in this blend are generally well tolerated for short-term use, though human safety data are limited overall. Mullein, slippery elm, marshmallow, wild yam, gentian, and plantain can all cause digestive upset (bloating, nausea, stomach discomfort) in some people.

Fennel may trigger allergic reactions, photosensitivity, or—very rarely—seizures; it can also cause bronchial asthma in susceptible individuals. Chickweed has caused contact dermatitis when applied to skin.

Plantain (psyllium) can cause bowel obstruction or choking if not taken with plenty of water, and occupational exposure to psyllium powder can trigger severe allergic reactions. The product contains alcohol, which may matter to you if you avoid it.

Because this is a proprietary blend, you cannot adjust individual ingredient amounts if one causes you trouble.

Side effects, ingredient by ingredient Mullein Slippery Elm Marshmallow Fennel Wild Yam Gentian Black Psyllium Chickweed

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 7 of the 8 matched ingredients can interact with medications — Black Psyllium, Fennel, Mullein, Gentian, Marshmallow, among others.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; heart-rhythm medications; lithium.
  • For scale: 2,099 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your doctor or pharmacist if you take birth control pills, estrogen therapy, or tamoxifen—fennel may reduce their effectiveness (Moderate severity). Also flag blood thinners or antiplatelet drugs like warfarin or aspirin, blood pressure medication, metformin, lithium, carbamazepine, olanzapine, or digoxin, as these may interact with one or more ingredients.

Space any oral medications at least 30–60 minutes away from this liquid to reduce absorption problems from the mucilage and fiber content.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This is a traditional herbal digestive blend with limited evidence backing most of its ingredients. If you take birth control pills, estrogen therapy, blood thinners, blood pressure medication, metformin, lithium, carbamazepine, olanzapine, digoxin, or several other medications, check your specific drugs with the tool on this page before starting—the interactions are real and could affect how your medicine works.

Talk with your doctor or pharmacist before adding this to your routine, especially if you're pregnant, breastfeeding, or have any digestive or bleeding concerns.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 8 of 8 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about GI Renew (Normal - 1) Glycerin, straight from the product label.

Brand Dr. Morse's Cellular Botanicals
Net contents 2 Ounce(s); 59 Milliliter(s)
Market status On market
Date entered into DSLD Feb 22, 2024
DSLD ID 302932
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for GI Renew (Normal - 1) Glycerin by Dr. Morse's Cellular Botanicals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.67 Dropperful(s)
Maximum serving Sizes:
2 Dropperful(s)
Servings per container
36
IngredientAmount% DV
Proprietary Blend1.6 mL--
Mullein0 NP--
Slippery Elm0 NP--
Marshmallow0 NP--
Fennel0 NP--
Wild Yam0 NP--
Gentian0 NP--
Plantain0 NP--
Chickweed0 NP--

Other ingredients: Glycerin, raw Honey, Water, Alcohol

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Support cellular regeneration with our tissue specific formulas! Created with over 45 years of experience and the highest quality ingredients available. Experience health and vitality like never before! Our Formulas are made with Organic, Wildcrafted or Consciously Cultivated Herbs

Made in the USA with global ingredients

Our Formulas are made with Organic, Wildcrafted or Consciously Cultivated Herbs

Suggested/Recommended/Usage/Directions

Suggested use by weight 25 lbs - 50 lbs 2/3 dropperful 50 lbs - 75 lbs 1 dropperful 75 lbs - 150 lbs 2 dropperfuls Add to a little water or juice 3 times a day.

Precautions

See our website for any precautions.

Keep out of reach of children.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Formula

Our Formulas are made with Organic, Wildcrafted or Consciously Cultivated Herbs

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

GI Renew (Normal - 1) Glycerin by Dr. Morse's Cellular Botanicals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

GI Renew (Normal - 1) Glycerin label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in GI Renew (Normal - 1) Glycerin by Dr. Morse's Cellular Botanicals

These are the 8 active ingredients this product is made of. Select any to open its full monograph.

Serving size0.67 Dropperful(s) Dosage formLiquid Servings per container36 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Blend

1.6 mL per serving

Other (inactive) ingredients: Glycerin, Raw Honey, Water, Alcohol. These complete the product’s ingredient list but are not active constituents.

Interaction report

GI Renew (Normal - 1) Glycerin by Dr. Morse's Cellular Botanicals Drug Interactions

Want to check YOUR meds against GI Renew (Normal - 1) Glycerin?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
2,098Drugs
2,098 Moderate

Ingredients driving the most interactions

Marshmallow 2,040
Plantain 2,025
Slippery Elm 2,022
Fennel 740
Gentian 172

Individual Drug Interactions

The ingredients in GI Renew (Normal - 1) Glycerin interact with 2,098 drugs. Click any drug to see the details.

7 of the 8 ingredients in GI Renew (Normal - 1) Glycerin interact with drugs. Each result below shows which ingredient is responsible. Marshmallow Plantain Slippery Elm Fennel Gentian Mullein Wild Yam

Each ingredient & the kinds of drugs it affects

For each ingredient in GI Renew (Normal - 1) Glycerin with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Marshmallow3 drug types · 2,040 drugs

Lithium

Theoretically, due to potential diuretic effects, marshmallow might reduce excretion and increase levels of lithium.
Marshmallow is thought to have diuretic properties. To avoid lithium toxicity, the dose of lithium might need to be decreased when used with marshmallow.

Likelihood Probable Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, marshmallow flower might have antiplatelet effects.
Animal research suggests that marshmallow flower extract has antiplatelet effects. However, the root and leaf of marshmallow, not the flower, are the plant parts most commonly found in dietary supplements. Theoretically, use of marshmallow flower with anticoagulant/antiplatelet drugs can have additive effects, and might increase the risk for bleeding in some patients.

Likelihood Unlikely Evidence D
Oral Drugs

Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Marshmallow contains mucilage which can affect oral drug absorption. To avoid changes in absorption, take marshmallow 30-60 minutes after oral medications.

Likelihood Possible Evidence D
Marshmallow full monograph & interactions

Plantain7 drug types · 2,025 drugs

Carbamazepine (Tegretol)

Theoretically, black psyllium might reduce the effects of carbamazepine and increase the risk for convulsions.
Theoretically, black psyllium might reduce carbamazepine absorption. A preliminary study using blond psyllium reported decreased carbamazepine bioavailability due to binding of the drug to psyllium, as well as reduction of available fluid in the gut for dissolution of the drug. This interaction may also occur with black psyllium.

Likelihood Probable Evidence D
Lithium

Theoretically, taking black psyllium at the same time as lithium might reduce lithium absorption.
The fiber in black psyllium might reduce lithium absorption and plasma levels. Some case reports describe a reduction in plasma lithium levels with concomitant administration of blond psyllium. This was reversed when psyllium was stopped. This interaction may also occur with black psyllium.

Likelihood Probable Evidence D
Metformin (Glucophage)

Theoretically, black psyllium might increase the therapeutic and adverse effects of metformin.
Animal research shows that concurrent consumption of blond psyllium with metformin slows and increases the absorption of metformin. This interaction may also occur with black psyllium. To avoid changes in absorption, take psyllium 30-60 minutes after metformin.

Likelihood Possible Evidence D
Olanzapine (Zyprexa)

Theoretically, taking black psyllium at the same time as olanzapine might reduce olanzapine absorption.
The fiber in black psyllium might decrease the absorption of olanzapine. A single case report describes a reduction in the effectiveness of olanzapine when it was concomitantly administered with an unspecified type of psyllium 3 grams orally twice daily. This effect was reversed when psyllium was stopped.

Likelihood Possible Evidence D
Digoxin (Lanoxin)

Theoretically, taking black psyllium at the same time as digoxin might reduce digoxin absorption and decrease digoxin levels.
Psyllium might bind digoxin in the gut. However, some clinical evidence suggests that psyllium does not impact digoxin absorption.

Likelihood Unlikely Evidence B
Ethinyl Estradiol

Theoretically, taking black psyllium at the same time as ethinyl estradiol might alter levels of estradiol.
Concurrent use of blond psyllium with ethinyl estradiol results in a slight increase in the extent of ethinyl estradiol absorption and a slower rate of absorption. This is unlikely to be clinically significant.

Likelihood Unlikely Evidence D
Oral Drugs

Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Psyllium seems to have variable effects on drug absorption. To avoid changes in absorption, take psyllium 30-60 minutes after oral medications. Animal research shows that blond psyllium delays and increases the absorption of metformin and ethinyl estradiol. Case reports and animal research suggest that blond psyllium might reduce absorption of lithium, digoxin, olanzapine, and carbamazepine. Finally, some pharmacokinetic studies show that psyllium does not affect the absorption of levothyroxine or warfarin. Although many of these studies evaluated blond psyllium, the fiber content in black psyllium may have similar effects.

Likelihood Possible Evidence B
Plantain full monograph & interactions

Slippery Elm1 drug type · 2,022 drugs

Oral Drugs

Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Slippery elm inner bark contains mucilage, which may interfere with the absorption of orally administered drugs.

Likelihood Possible Evidence D
Slippery Elm full monograph & interactions

Fennel6 drug types · 740 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, fennel might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.

Animal research suggests that fennel oil has antithrombotic and antiplatelet effects.

Likelihood Possible Evidence D
Ciprofloxacin (Cipro)

Theoretically, fennel might decrease the levels and clinical effects of ciprofloxacin.

Animal research shows that fennel reduces ciprofloxacin bioavailability by nearly 50%, possibly due to the metal cations such as calcium, iron, and magnesium contained in fennel. This study also found that fennel increased tissue distribution and slowed elimination of ciprofloxacin.

Likelihood Probable Evidence D
Contraceptive Drugs

Theoretically, taking large amounts of fennel might decrease the effects of contraceptive drugs due to competition for estrogen receptors.

Some constituents of fennel have estrogenic activity.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.

In vitro research suggests that fennel inhibits CYP3A4 enzyme activity. This effect has not been reported in humans.

Likelihood Possible Evidence D
Estrogens

Theoretically, taking large amounts of fennel might interfere with hormone replacement therapy due to competition for estrogen receptors.

Some constituents of fennel have estrogenic activity.

Likelihood Possible Evidence D
Tamoxifen (Nolvadex)

Theoretically, taking large amounts of fennel might decrease the antiestrogenic effect of tamoxifen.

Some constituents of fennel have estrogenic activity, which may interfere with the antiestrogenic activity of tamoxifen.

Likelihood Possible Evidence D
Fennel full monograph & interactions

Gentian1 drug type · 172 drugs

Antihypertensive Drugs

Theoretically, taking gentian with antihypertensive drugs might increase the risk of hypotension.
In vitro research shows that gentian can cause vasodilation and lower blood pressure.

Likelihood Possible Evidence D
Gentian full monograph & interactions

Mullein1 drug type · 122 drugs

Anticoagulant/Antiplatelet Drugs

Lab tests on extracts from different parts of common and dense-flowered mullein plants show that they do have some blood-thinning effects, as they increase the time it takes for blood to clot. This is likely due to at least one of the known constituents of muellein, triterpenoid saponins. However, the effects appear to be mild and results have been inconsistent. Extracts from different plant parts have been show to have varying anticoagulant strengths, with water-based ones being more potent than alcohol-based extracts.

Likelihood Unlikely Evidence A
Mullein full monograph & interactions

Wild Yam1 drug type · 41 drugs

Estrogens

Theoretically, wild yam might increase or decrease the effects of estrogen.
Wild yam root shows estrogenic and anti-estrogenic effects in vitro. Theoretically, wild yam might interfere with hormone therapy.

Likelihood Possible Evidence D
Wild Yam full monograph & interactions
The maker

Brand information

Manufacturer and brand details for GI Renew (Normal - 1) Glycerin, from the product label.

Dr. Morse's Cellular Botanicals

See all Dr. Morse's Cellular Botanicals products
Name
Western Botanicals FL, LLC
City
Spanish Fork
State
UT
ZipCode
84660
Web Address
DMHHC.com
Pharmacist Counseling Corner

GI Renew (Normal - 1) Glycerin by Dr. Morse's Cellular Botanicals: Common Questions

Does GI Renew (Normal - 1) Glycerin by Dr. Morse's Cellular Botanicals interact with any medications?
Yes. Based on its ingredients, GI Renew (Normal - 1) Glycerin has a known interaction with 2,098 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
GI Renew (Normal - 1) Glycerin contains 8 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does fennel in this product affect birth control?
Fennel has estrogenic activity—meaning it mimics some effects of estrogen—which theoretically could reduce how well birth control pills and hormone replacement therapy work. The risk is higher with concentrated amounts. If you're on hormonal birth control or estrogen therapy, check with your doctor or pharmacist before starting this blend.
Is this safe during pregnancy?
Most ingredients in this blend lack enough safety data during pregnancy and are best avoided—mullein, slippery elm, marshmallow, fennel, wild yam, and gentian all carry cautions against pregnancy use. Plantain is considered likely safe, and chickweed also carries a likely-safe rating, but because this is a blend of multiple ingredients with uncertain safety, talk with your doctor or pharmacist before taking it while pregnant.
Can I take this with my blood pressure medication?
Gentian in this blend may lower blood pressure and theoretically add to the effect of your medication. Space the doses apart and let your doctor or pharmacist know you're taking both so they can monitor your blood pressure.
What does plantain do in this product?
Plantain (also called psyllium) is a source of soluble fiber traditionally used to support digestive health. It's effective for constipation and likely effective for heart health, but it can interfere with absorption of several medications, so space it at least 30–60 minutes away from any pills you take and drink plenty of water with it.
Does this product have fillers or just herbs?
This liquid contains the herbal blend plus glycerin, raw honey, water, and alcohol as inactive ingredients that help preserve and deliver the herbs. These are common in liquid supplements and serve a purpose—there are no truly "empty" fillers here, but yes, other ingredients are present beyond the botanicals themselves.
Can I take this if I'm on metformin for diabetes?
Plantain in this product may slow and increase how your body absorbs metformin, which could change your blood sugar levels. Space the two at least 30–60 minutes apart and check with your doctor or pharmacist to make sure they work well together in your situation.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if GI Renew (Normal - 1) Glycerin is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

GI Renew (Normal - 1) Glycerin label
Go deeper

The Full Monographs Behind GI Renew (Normal - 1) Glycerin’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Mullein

Interacts with 122 drugs

Mullein is a traditional herbal remedy most often used as a tea or syrup to soothe coughs, sore throats, and respiratory irritation. High-quality human studies are lacking, so its benefits a...

Read the full Mullein monograph → Herb & supplement monograph

Slippery Elm

Interacts with 2,022 drugs

Slippery elm is a traditional herbal remedy made from the inner bark of a North American elm tree, used mainly to soothe sore throats and irritated digestive tracts. Its mucilage can coat an...

Read the full Slippery Elm monograph → Herb & supplement monograph

Marshmallow

Interacts with 2,040 drugs

Marshmallow root is a traditional herb rich in soothing, gel-like fibers called mucilage, which is why it has long been used for coughs, sore throats, and stomach irritation. Evidence for th...

Read the full Marshmallow monograph → Herb & supplement monograph

Fennel

Interacts with 740 drugs

Fennel is a Mediterranean herb widely used as a food and spice, and traditionally taken for digestive complaints, colic, and menstrual cramps. Some small studies suggest possible benefit for...

Read the full Fennel monograph → Herb & supplement monograph

Wild Yam

Interacts with 41 drugs

Wild yam is a root traditionally used for menopausal symptoms, cramps, and as a so-called 'natural' hormone supplement, but solid human evidence for these uses is lacking. Despite popular cl...

Read the full Wild Yam monograph → Herb & supplement monograph

Gentian

Interacts with 172 drugs

Gentian is a very bitter root traditionally used to stimulate appetite and ease mild digestive complaints, often as part of "bitters" before meals. The evidence is mostly traditional and pre...

Read the full Gentian monograph → Herb & supplement monograph

Black Psyllium

Interacts with 2,025 drugs

Black psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. It is best known and most studied for rel...

Read the full Black Psyllium monograph → Herb & supplement monograph

Chickweed

Chickweed is a common edible wild plant traditionally used on the skin for itching and minor irritation, and taken as a tea or tincture for various complaints. Solid human studies are lackin...

Read the full Chickweed monograph →
Sources

Sources & How We Checked

GI Renew (Normal - 1) Glycerin's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 61 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Mullein 2 references
  1. Castro AI, Carmona JB, Gonzales FG, Nestar OB. Occupational airborne dermatitis from gordolobo (Verbascum densiflorum). Contact Dermatitis 2006;55(5):301.
  2. Flores Echaiz C, Al Ali A, Cao AQ, Sasseville D. Simultaneous contact dermatitis caused by Asteraceae and Verbascum thapsus. Contact Dermatitis 2017;76(5):316-8.

See these in context on the Mullein monograph →

Slippery Elm 3 references
  1. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  2. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  3. Czarnecki D, Nixon R, Bekhor P, and et al. Delayed prolonged contact urticaria from the elm tree. Contact Dermatitis 1993;28:196-197. PubMed

See these in context on the Slippery Elm monograph →

Marshmallow 5 references
  1. Monographs on the medicinal uses of plant drugs. Exeter, UK: European Scientific Co-op Phytother, 1997.
  2. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
  3. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  4. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  5. Hage-Sleiman R, Mroueh M, Daher CF. Pharmacological evaluation of aqueous extract of Althaea officinalis flower grown in Lebanon. Pharm Biol 2011;49(3):327-33.

See these in context on the Marshmallow monograph →

Fennel 17 references
  1. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
  2. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  3. Zhu M, Wong PY, Li RC. Effect of oral administration of fennel (Foeniculum vulgare) on ciprofloxacin absorption and disposition in the rat. J Pharm Pharmacol 1999;51:1391-6.
  4. Gral N, Beani JC, Bonnot D, et al. [Plasma levels of psoralens after celery ingestion]. Ann Dermatol Venereol 1993;120:599-603.
  5. Burkhard PR, Burkhardt K, Haenggeli CA, Landis T. Plant-induced seizures: reappearance of an old problem. J Neurol 1999;246:667-70. PubMed
  6. Rosti L, Nardini A, Bettinelli ME, Rosti D. Toxic effects of a herbal tea mixture in two newborns. Acta Paediatrica 1994;83:683. PubMed
  7. Cuzzolin L, Zaffani S, and Benoni G. Safety implications regarding use of phytomedicines. Eur.J Clin Pharmacol. 2006;62:37-42. PubMed
  8. Tognolini, M., Ballabeni, V., Bertoni, S., Bruni, R., Impicciatore, M., and Barocelli, E. Protective effect of Foeniculum vulgare essential oil and anethole in an experimental model of thrombosis. Pharmacol.Res 2007;56(3):254-260. PubMed
  9. Subehan, Usia, T., Iwata, H., Kadota, S., and Tezuka, Y. Mechanism-based inhibition of CYP3A4 and CYP2D6 by Indonesian medicinal plants. J Ethnopharmacol. 5-24-2006;105(3):449-455. PubMed
  10. Tognolini, M., Barocelli, E., Ballabeni, V., Bruni, R., Bianchi, A., Chiavarini, M., and Impicciatore, M. Comparative screening of plant essential oils: phenylpropanoid moiety as basic core for antiplatelet activity. Life Sci. 2-23-2006;78(13):1419-1432. PubMed
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Wild Yam 7 references
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  6. Zeng M, Zhang L, Li M, et al. Estrogenic effects of the extracts from the Chinese Yam (Dioscorea opposite Thunb.) and its effective compounds in vitro and in vivo. Molecules. 2018 Jan 23;23(2). Pii: E11. PubMed
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Gentian 5 references
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  2. Marz RW, Ismail C, Popp MA. Action profile and efficacy of a herbal combination preparation for the treatment of sinusitis. Wien Med Wochenschr 1999;149:202-8.
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See these in context on the Gentian monograph →

Black Psyllium 18 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
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See these in context on the Black Psyllium monograph →

Chickweed 4 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Jovanovic M, Mimica-Dukic N, Poljacki M, Boza P. Erythema multiforme due to contact with weeds: a recurrence after patch testing. Contact Dermatitis 2003;48:17-25. PubMed
  3. Jovanovic, M., Poljacki, M., Mimica-Dukic, N., Boza, P., Vujanovic, Lj, Duran, V., and Stojanovic, S. Sesquiterpene lactone mix patch testing supplemented with dandelion extract in patients with allergic contact dermatitis, atopic dermatitis and non-alle
  4. Poljacki, M., Jovanovic, M., Boza, P., Mimica-Dukic, N., Petrovic, A., and Novovic, Z. [Is Vojvodina a risk area for contact weed allergies?]. Med Pregl. 2005;58(3-4):123-126. PubMed

See these in context on the Chickweed monograph →

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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