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Dietary supplement

Glow Skin Ingredients & Drug Interactions

by AdvoCare

Glow Skin label
See full label image
Softgel Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Glow Skin against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Glow Skin is a dietary supplement by AdvoCare with 2 active ingredients. Its ingredients are commonly taken for antioxidant support, skin health and aging, eye health.Based on those ingredients, 758 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Astaxanthin, mixed Tocotrienols. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Glow Skin by AdvoCare

Ask about any prescription or over-the-counter medication and we check it for interactions with Glow Skin by AdvoCare — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Glow Skin by AdvoCare

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 30, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 2 active ingredients.

Glow Skin is a 2-ingredient softgel capsule centered on astaxanthin and mixed tocotrienols — both are compounds with antioxidant properties. The capsules also contain extra virgin olive oil, gelatin, purified water, and glycerin as inactive ingredients to deliver and stabilize the active compounds.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded its ingredients' overall clinical evidence instead.

Moderate

Some clinical evidence supports its ingredients for:

  • Diabetes via Tocotrienols Possibly Effective
Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredients' overall clinical evidence instead.
  • On file: Diabetes — rated "Possibly Effective" (Tocotrienols) (Natural Medicines).

The evidence supporting these ingredients is mixed. Astaxanthin has insufficient reliable evidence to rate its use for age-related cognitive decline, macular degeneration, aging skin, Alzheimer disease, athletic performance, or carpal tunnel syndrome — meaning the science just isn't solid enough yet to say whether it works for those purposes.

Mixed tocotrienols show possibly effective evidence for diabetes, but possibly ineffective evidence for cholesterol, and insufficient evidence for alopecia areata and breast cancer. In short, neither ingredient has strong proof it delivers the results this product implies.

The evidence, ingredient by ingredient Astaxanthin Tocotrienols

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Both ingredients are generally well tolerated in studies, but long-term safety data — especially at supplement doses — is limited. Astaxanthin may cause abdominal pain, diarrhea, or reddish-colored stool; a small number of trial participants on higher doses reported severe stomach pain.

Mixed tocotrienols appear to have no adverse effects in oral trials, though topical formulations have rarely caused mild itching or contact dermatitis. For pregnancy and breastfeeding, the safety data are not sufficient to recommend this product.

Astaxanthin should be avoided during pregnancy and while breastfeeding. Mixed tocotrienols should also be avoided in pregnancy, and while breastfeeding there's little safety information — so talk with your doctor or pharmacist before using it.

Neither ingredient has enough data on file to know whether supplemental doses are safe during these periods.

Side effects, ingredient by ingredient Astaxanthin Tocotrienols

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Astaxanthin, Tocotrienols.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 759 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking AdvoCare Glow Skin, double-check any medications metabolized by your liver's CYP3A4 or CYP2B6 enzyme systems — astaxanthin may lower their levels (Moderate severity). Also flag any blood thinners or antiplatelet drugs you take, since mixed tocotrienols theoretically could increase bleeding risk (Minor severity), though this hasn't been reported in humans.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

Glow Skin may appeal to you if you're interested in antioxidant support, but the evidence that either ingredient works for skin aging or other common uses is not established in our data. If you take any medications — especially blood thinners, heart drugs, or anything metabolized by your liver — you should check your exact prescriptions with the tool on this page and discuss them with your own doctor or pharmacist before starting.

Pregnant or breastfeeding? Talk it over with your healthcare provider first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated May 19, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Glow Skin, straight from the product label.

Brand AdvoCare
Net contents 30 Softgel(s)
Market status On market
Date entered into DSLD May 19, 2022
DSLD ID 265478
Product type Other Combinations
Supplement form Softgel Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Glow Skin by AdvoCare, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
Servings per container
30
IngredientAmount% DV
Astaxanthin0 NP--
mixed Tocotrienols0 NP--

Other ingredients: extra virgin Olive Oil, Gelatin, Water, Purified, Glycerin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

For more information go to advocare.com

Suggested/Recommended/Usage/Directions

Directions For Use: Take one softgel per day with a meal.

Precautions

Caution: Check with your healthcare professional before using this product.

This product is not intended for pregnant or nursing women.

Keep out of reach of children.

Storage

Store away from excessive heat, light and humidity.

Formula

Astaxanthin and mixed tocotrienols

FDA Statement of Identity

Dietary Supplement

Brand IP Statement(s)

AstaReal is a registered trademark of Fuji Chemical Industries Co., Ltd.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Glow Skin by AdvoCare label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Glow Skin label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Glow Skin by AdvoCare

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Astaxanthin

Interacts with
671 drugs
0 NP per serving

Astaxanthin is a reddish carotenoid pigment with strong antioxidant activity in the lab, and it is widely promoted for skin, eye, heart, and exercise...

Astaxanthin monograph & interactions

Mixed Tocotrienols

Interacts with
122 drugs
0 NP per serving

Tocotrienols are a less common form of vitamin E with strong antioxidant activity studied mostly for cholesterol, liver, and heart health. Early resea...

Mixed Tocotrienols monograph & interactions

Other (inactive) ingredients: Extra virgin Olive Oil, Gelatin, Water, Purified, Glycerin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Glow Skin by AdvoCare Drug Interactions

Want to check YOUR meds against Glow Skin?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
758Drugs
671 Moderate 87 Minor

Ingredients driving the most interactions

Astaxanthin 671
mixed Tocotrienols 122

Individual Drug Interactions

The ingredients in Glow Skin interact with 758 drugs. Click any drug to see the details.

2 of the 2 ingredients in Glow Skin interact with drugs. Each result below shows which ingredient is responsible. Astaxanthin mixed Tocotrienols

Each ingredient & the kinds of drugs it affects

For each ingredient in Glow Skin with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Astaxanthin2 drug types · 671 drugs

Cytochrome P450 2B6 (Cyp2B6) Substrates

Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP2B6.
In vitro research shows that astaxanthin induces cytochrome CYP2B6 enzyme activity in human hepatocytes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP3A4.
In vitro research shows that astaxanthin induces CYP3A4 enzyme activity in human hepatocytes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Astaxanthin full monograph & interactions

mixed Tocotrienols1 drug type · 122 drugs

Anticoagulant/Antiplatelet Drugs

Concomitant use of tocotrienols with anticoagulant or antiplatelet agents might increase the risk of bleeding. However, this has not been reported in humans.
Taking tocotrienols orally inhibits experimentally-induced platelet aggregation in humans. Theoretically tocotrienols might increase the risk of bleeding if taken with antiplatelet or anticoagulant drugs. However, tocotrienols 400-800 mg daily have been used with aspirin and/or clopidogrel for 1 year with no clear cumulative antiplatelet effects and no reports of bleeding.

Likelihood Unlikely Evidence B
mixed Tocotrienols full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Glow Skin, from the product label.

AdvoCare

Name
AdvoCare International, LLC
City
Richardson
State
TX
ZipCode
75082
Phone Number
800-542-4800
Web Address
advocare.com
Pharmacist Counseling Corner

Glow Skin by AdvoCare: Common Questions

Does Glow Skin by AdvoCare interact with any medications?
Yes. Based on its ingredients, Glow Skin has a known interaction with 758 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Glow Skin contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
No — there isn't enough safety data for astaxanthin during pregnancy or breastfeeding, so it's best to avoid it. Mixed tocotrienols should also be avoided in pregnancy, and safety while breastfeeding is unclear. Talk with your doctor or pharmacist before using this product.
Does astaxanthin actually work for aging skin?
We don't have reliable evidence to say. The data we hold rates astaxanthin as having insufficient reliable evidence for aging skin, so it's not proven to work for that purpose.
What are the most common side effects?
Astaxanthin may cause abdominal pain, diarrhea, or red-colored stool. Mixed tocotrienols appear to have no reported side effects from oral use in clinical trials. Both ingredients are generally well tolerated, but long-term safety data are limited.
I take a blood thinner — is this safe?
Mixed tocotrienols in this product may theoretically increase bleeding risk with blood thinners, though this hasn't been reported in humans. Use the interaction checker on this page to search your exact medication, then talk with your doctor or pharmacist before taking it.
What do tocotrienols do?
Tocotrienols are antioxidant compounds; mixed tocotrienols show possibly effective evidence for diabetes but possibly ineffective evidence for cholesterol. Their effects for other uses aren't well established.
Are there fillers in this product?
Yes — beyond the two active ingredients, the capsule contains extra virgin olive oil, gelatin, purified water, and glycerin as inactive ingredients to deliver the formula.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Glow Skin is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Glow Skin label
Go deeper

The Full Monographs Behind Glow Skin’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Astaxanthin

Interacts with 671 drugs

Astaxanthin is a reddish carotenoid pigment with strong antioxidant activity in the lab, and it is widely promoted for skin, eye, heart, and exercise benefits. Early human studies are promis...

Read the full Astaxanthin monograph → Herb & supplement monograph

Tocotrienols

Interacts with 122 drugs

Tocotrienols are a less common form of vitamin E with strong antioxidant activity studied mostly for cholesterol, liver, and heart health. Early research is interesting but far from conclusi...

Read the full Tocotrienols monograph →
Sources

Sources & How We Checked

Glow Skin's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 7 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Astaxanthin 3 references
  1. Kupcinskas L, Lafolie P, Lignell A, et al. Efficacy of the natural antioxidant astaxanthin in the treatment of functional dyspepsia in patients with or without Helicobacter pylori infection: A prospective, randomized, double blind, and placebo-controlled
  2. Kistler, A., Liechti, H., Pichard, L., Wolz, E., Oesterhelt, G., Hayes, A., and Maurel, P. Metabolism and CYP-inducer properties of astaxanthin in man and primary human hepatocytes. Arch.Toxicol. 2002;75(11-12):665-675. PubMed
  3. Choi HD, Youn YK, Shin WG. Positive effects of astaxanthin on lipid profiles and oxidative stress in overweight subjects. Plant Foods Hum Nutr. 2011;66:363-369. PubMed

See these in context on the Astaxanthin monograph →

Tocotrienols 4 references
  1. Mensink RP, van Houwelingen AC, Kromhout D, Hornstra G. A vitamin E concentrate rich in tocotrienols had no effect on serum lipids, lipoproteins, or platelet function in men with mildly elevated serum lipid concentrations. Am J Clin Nutr 1999;69:213-9. PubMed
  2. Baumann LS, Spencer JS. The effects of topical vitamin E on the cosmetic appearance of scars. Dermatol Surg 1999;25:311-5. PubMed
  3. Khoo TL, Halim AS, Zakaria Z, Mat Saad AZ, Wu LY, Lau HY. A prospective, randomised, double-blinded trial to study the efficacy of topical tocotrienol in the prevention of hypertrophic scars. J Plast Reconstr Aesthet Surg. 2011 Jun;64(6):e137-45. Epub 201 PubMed
  4. Slivka A, Rink C, Paoletto D, Sen CK. Platelet function in stroke/transient ischemic attack patients treated with tocotrienol. FASEB J. 2020;34(9):11838-11843. PubMed

See these in context on the Tocotrienols monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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