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Dietary supplement

Glucomannan & Chicory Root (FOS) Vanilla Flavor Ingredients & Drug Interactions

by TerraVita

Glucomannan & Chicory Root (FOS) Vanilla Flavor label
See full label image
Liquid Category: Botanical With Nutrients
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Glucomannan & Chicory Root (FOS) Vanilla Flavor against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Glucomannan & Chicory Root (FOS) Vanilla Flavor is a dietary supplement by TerraVita with 1 active ingredient. Its ingredients are commonly taken for weight loss and appetite control, constipation, high cholesterol.Based on those ingredients, 2,050 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Glucomannan & Chicory Root Glycerite Liquid Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Glucomannan & Chicory Root (FOS) Vanilla Flavor by TerraVita

Ask about any prescription or over-the-counter medication and we check it for interactions with Glucomannan & Chicory Root (FOS) Vanilla Flavor by TerraVita — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Glucomannan & Chicory Root (FOS) Vanilla Flavor by TerraVita

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 30, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 2 active ingredients.
  • “Glucomannan & Chicory Root Glycerite Liquid Extract” is listed as a grouped ingredient — the label gives one combined amount (0.13 mL) without saying how much of each component you get.

This liquid contains two active ingredients: glucomannan, a dietary fiber from the konjac plant root, and chicory root extract (delivered as a glycerite, meaning it's dissolved in glycerin). Glucomannan is a soluble fiber that absorbs water and bulks up in your digestive tract; chicory root is traditionally used for digestion and contains compounds that may affect blood sugar.

The product also includes glycerin and vanilla flavor as inactive ingredients to improve taste and texture.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded its ingredients' overall clinical evidence instead.

Moderate

Some clinical evidence supports its ingredients for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredients' overall clinical evidence instead.
  • On file: Constipation — rated "Possibly Effective" (Glucomannan) (Natural Medicines).
  • On file: Diabetes — rated "Possibly Effective" (Glucomannan) (Natural Medicines).
  • On file: Hyperlipidemia — rated "Possibly Effective" (Glucomannan) (Natural Medicines).

Glucomannan is possibly effective for constipation, diabetes, and high cholesterol. The evidence for chicory root, however, is not established in the data we hold — studies on its use for liver health, joint pain, indigestion, and cholesterol have not yielded reliable evidence yet.

For high blood pressure, there isn't enough reliable evidence to rate either ingredient. If you're considering this product for a specific health goal, talk with your doctor about whether the evidence supports that use in your case.

The evidence, ingredient by ingredient Glucomannan Chicory

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Glucomannan is generally well tolerated when taken with plenty of water, but it can cause gas, bloating, abdominal pain, diarrhea, nausea, or constipation — especially at doses above 3 grams daily. Rare but serious cases of choking or digestive tract blockage have been reported, mainly when the dry powder or tablets were swallowed without enough liquid.

Chicory is generally well tolerated in food amounts and may cause mild gas or bloating, but can trigger allergies in people sensitive to the ragweed family of plants. For pregnancy, the safety data on glucomannan is insufficient — there isn't enough reliable information to know either way, so talk with your doctor before using it during pregnancy.

Chicory in medicinal amounts is possibly unsafe during pregnancy due to concerns about uterine stimulation. For breastfeeding, there's little reliable safety information on either ingredient, so medicinal amounts are best avoided — discuss this with your doctor or pharmacist.

Side effects, ingredient by ingredient Glucomannan Chicory

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Chicory, Glucomannan.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 2,051 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check with your doctor or pharmacist if you take oral medications of any kind (Moderate severity) — glucomannan may reduce how much of the drug your body absorbs — or if you take antidiabetes drugs (Moderate severity), because chicory root may increase the risk of low blood sugar. Timing your doses apart from your medications may help, but your healthcare provider needs to know you're adding this supplement.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

Glucomannan & Chicory Root may help with constipation, blood sugar, or cholesterol if the evidence supports your reason for using it — but the ingredient interactions with oral medications and diabetes drugs are real and worth discussing. If you take any regular medications, especially for diabetes or blood pressure, check with your doctor or pharmacist before starting this product.

Always take it with a full glass of water to avoid choking or blockage.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 13, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Glucomannan & Chicory Root (FOS) Vanilla Flavor, straight from the product label.

Brand TerraVita
Barcode (UPC) 064435225247
Net contents 1 Fluid Ounce(s); 30 mL
Market status On market
Date entered into DSLD Dec 13, 2022
DSLD ID 281549
Product type Botanical With Nutrients
Supplement form Liquid
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Glucomannan & Chicory Root (FOS) Vanilla Flavor by TerraVita, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
25 Drop(s)
Maximum serving Sizes:
40 Drop(s)
Servings per container
227
UPC/BARCODE
064435225247
IngredientAmount% DV
Glucomannan0 NP--
Glucomannan & Chicory Root Glycerite Liquid Extract0.13 mL--
Chicory Root Glycerite Liquid Extract0 NP--

Other ingredients: Glycerin, Vanilla Flavor

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

Copyright 2018 TerraVita - Distributed by ZooScape LLC, All Rights Reserved.

Formula

Vanilla Flavored Glycerite liquid extract (1:5)

Formulation

Alcohol free

Suggested/Recommended/Usage/Directions

Suggested Use: Take 25-40 drops of extract in a small amount of warm water 3-4 times daily. Shake well before using.

Precautions

Keep away from children.

Do not use if safety seal around cap is broken or missing.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Glucomannan & Chicory Root (FOS) Vanilla Flavor by TerraVita label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Glucomannan & Chicory Root (FOS) Vanilla Flavor label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Glucomannan & Chicory Root (FOS) Vanilla Flavor by TerraVita

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size25 Drop(s) Dosage formLiquid Servings per container227 Amounts shown are per serving.

Glucomannan & Chicory Root Glycerite Liquid Extract

Interacts with
2,022 drugs
0.13 mL per serving

Glucomannan is a soluble fiber from the konjac root that swells into a gel in your stomach, which may help with mild weight loss, constipation, and mo...

Glucomannan & Chicory Root Glycerite Liquid Extract monograph & interactions

Other (inactive) ingredients: Glycerin, Vanilla Flavor. These complete the product’s ingredient list but are not active constituents.

Interaction report

Glucomannan & Chicory Root (FOS) Vanilla Flavor by TerraVita Drug Interactions

Want to check YOUR meds against Glucomannan & Chicory Root (FOS) Vanilla Flavor?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
2,050Drugs
2,050 Moderate

Ingredients driving the most interactions

Glucomannan & Chicory Root Glycerite Liquid Extract 2,022

Individual Drug Interactions

The ingredients in Glucomannan & Chicory Root (FOS) Vanilla Flavor interact with 2,050 drugs. Click any drug to see the details.

1 of the 1 ingredient in Glucomannan & Chicory Root (FOS) Vanilla Flavor interact with drugs. Each result below shows which ingredient is responsible. Glucomannan & Chicory Root Glycerite Liquid Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Glucomannan & Chicory Root (FOS) Vanilla Flavor with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Glucomannan & Chicory Root Glycerite Liquid Extract1 drug type · 2,022 drugs

Oral Drugs

Theoretically, glucomannan may decrease absorption of drugs taken orally.
Due to its viscosity and bulking effects, there is concern that glucomannan can decrease the absorption of oral drugs. A small clinical study in healthy volunteers shows that taking glyburide 2.5 mg plus glucomannan 3.9 grams with breakfast reduces plasma levels of glyburide when compared with breakfast and glyburide alone. In addition, animal research demonstrates this effect on amoxicillin, but shows increased absorption of metronidazole. This mouse model also demonstrates that metronidazole elimination is prolonged, but amoxicillin elimination is enhanced by 38%; glucomannan may also affect the distribution of some drugs. To avoid changes in absorption, take glucomannan 30-60 minutes after taking oral drugs.

Likelihood Probable Evidence B
Glucomannan & Chicory Root Glycerite Liquid Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Glucomannan & Chicory Root (FOS) Vanilla Flavor, from the product label.

TerraVita

See all TerraVita products
Name
ZooScape LLC
Phone Number
844-449-0444
Web Address
www.ZooScape.com
Pharmacist Counseling Corner

Glucomannan & Chicory Root (FOS) Vanilla Flavor by TerraVita: Common Questions

Does Glucomannan & Chicory Root (FOS) Vanilla Flavor by TerraVita interact with any medications?
Yes. Based on its ingredients, Glucomannan & Chicory Root (FOS) Vanilla Flavor has a known interaction with 2,050 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Glucomannan & Chicory Root (FOS) Vanilla Flavor contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm on diabetes medication?
Not without checking with your doctor first. Chicory root in this product may increase the risk of low blood sugar if you take antidiabetes drugs, and glucomannan may also reduce how well your medication absorbs. Your doctor can advise you on whether it's safe and how to time your doses.
What are the most common side effects?
Mild digestive upset is most common — abdominal pain, bloating, gas, diarrhea, or nausea. These usually happen when you take it without enough water or at higher doses. Serious blockage or choking is rare but can occur if you don't drink plenty of liquid with it.
Is this safe during pregnancy?
There isn't enough reliable safety data on glucomannan to know either way, and chicory in medicinal amounts is considered possibly unsafe because of concerns about uterine effects. Talk with your doctor before using this product while pregnant.
Do I need to space this out from my other medications?
Possibly yes — because glucomannan can interfere with how your body absorbs oral drugs, your doctor or pharmacist may want you to take this product a few hours apart from your medications. Don't assume a timing on your own; ask them for a specific schedule.
What is chicory root used for in this product?
Chicory root is included as a digestive herb and for its potential effects on blood sugar and cholesterol. However, we don't have reliable evidence that it works for those purposes yet, so it's mainly a traditional ingredient.
Can I take this while breastfeeding?
There isn't enough reliable safety information on either glucomannan or chicory to know whether medicinal amounts are safe during breastfeeding. Talk with your doctor or pharmacist about whether it's okay in your situation.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Glucomannan & Chicory Root (FOS) Vanilla Flavor label
Go deeper

The Full Monographs Behind Glucomannan & Chicory Root (FOS) Vanilla Flavor’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Glucomannan

Interacts with 2,022 drugs

Glucomannan is a soluble fiber from the konjac root that swells into a gel in your stomach, which may help with mild weight loss, constipation, and modestly lowering cholesterol. It is gener...

Read the full Glucomannan monograph → Herb & supplement monograph

Chicory

Interacts with 86 drugs

Chicory is best known as a caffeine-free coffee substitute and as a source of inulin, a soluble prebiotic fiber that may support digestion and regularity. Strong human evidence for most othe...

Read the full Chicory monograph →
Sources

Sources & How We Checked

Glucomannan & Chicory Root (FOS) Vanilla Flavor's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 28 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Glucomannan 15 references
  1. Henry DA, Mitchell AS, Aylward J, et al. Glucomannan and risk of oesophageal obstruction. Br Med J 1986;292:591-2. PubMed
  2. Shima K, Tanaka A, Ikegami H, et al. Effect of dietary fiber, glucomannan, on absorption of sulfonylurea in man. Horm Metab Res 1983;15:1-3. PubMed
  3. Villaverde, A. F., Benlloch, S., Berenguer, M., Miguel, Rayon J., Pina, R., and Berenguer, J. Acute hepatitis of cholestatic type possibly associated with the use of glucomannan (amorphophalus konjac). J Hepatol. 2004;41(6):1061-1062. PubMed
  4. Yoshida, M., Vanstone, C. A., Parsons, W. D., Zawistowski, J., and Jones, P. J. Effect of plant sterols and glucomannan on lipids in individuals with and without type II diabetes. Eur.J Clin Nutr. 2006;60(4):529-537. PubMed
  5. Wood, R. J., Fernandez, M. L., Sharman, M. J., Silvestre, R., Greene, C. M., Zern, T. L., Shrestha, S., Judelson, D. A., Gomez, A. L., Kraemer, W. J., and Volek, J. S. Effects of a carbohydrate-restricted diet with and without supplemental soluble fiber
  6. Vanderbeek, P. B., Fasano, C., O'Malley, G., and Hornstein, J. Esophageal obstruction from a hygroscopic pharmacobezoar containing glucomannan. Clin Toxicol.(Phila) 2007;45(1):80-82. PubMed
  7. Bernstein, J. A., Crandall, M. S., and Floyd, R. Respiratory sensitization of a food manufacturing worker to konjac glucomannan. J Asthma 2007;44(8):675-680. PubMed
  8. Shichijo, K., Kobayashi, Y., Fueki, R., Shimoyama, K., and Masaya, M. [2 cases of konjac bronchial asthma found outside the "konnyaku" producing district]. Arerugi 1969;18(2):97-100.
  9. Carabin IG, Lyon MR, Wood S, et al. Supplementation of the diet with the functional fiber PolyGlycoplex is well tolerated by healthy subjects in a clinical trial. Nutr J 2009;8:9. PubMed
  10. Lyon MR, Reichert RG. The effect of a novel viscous polysaccharide along with lifestyle changes on short-term weight loss and associated risk factors in overweight and obese adults: an observational retrospective clinical program analysis. Altern Med Rev
  11. Lyon M, Wood S, Pelletier X, et al. Effects of a 3-month supplementation with a novel soluble highly viscous polysaccharide on anthropometry and blood lipids in nondieting overweight or obese adults. J Hum Nutr Diet 2011;24(4):351-9. PubMed
  12. Han Y, Zhang L, Liu XQ, Zhao ZJ, Lv LX. Effect of glucomannan on functional constipation in children: a systematic review and meta-analysis of randomised controlled trials. Asia Pac J Clin Nutr 2017;26(3):471-7.
  13. Health Canada Safety Alert. Health Canada Advises Canadians that natural health products containing glucomannan may cause serious choking if used with insufficient fluid. January 29, 2010. Alert # RA-110003825. https://healthycanadians.gc.ca/recall-alert-
  14. Mortensen A, Aguilar F, Crebelli, et al. EFSA Panel on Food Additives and Nutrient Sources added to Food. Re-evaluation of konjac gum (E 425 i) and konjac glucomannan (E425 ii) as food additives. EFSA Journal 2017;15(6):4864.
  15. Zhang Y, Aldamarany WAS, Song G, et al. Influence of konjac glucomannan and its derivatives on the oral pharmacokinetics of antimicrobial agent in antibiotics cocktails: Keep vigilant on dietary fiber supplement. Int J Biol Macromol 2023;251:126306. PubMed

See these in context on the Glucomannan monograph →

Chicory 13 references
  1. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  2. Stone-Dorshow T, Levitt MD. Gaseous response to ingestion of a poorly absorbed fructo-oligosaccharide sweetener. Am J Clin Nutr 1987;46:61-5. PubMed
  3. Briet F, et al. Symptomatic response to varying levels of fructo-oligosaccharides consumed occasionally or regularly. Eur J Clin Nutr 1995;49:501-7.
  4. Bouhnik Y, Vahedi K, Achour L, et al. Short-chain fructo-oligosaccharide administration dose-dependently increases fecal bifidobacteria in healthy humans. J Nutr 1999;129:113-6. PubMed
  5. Cummings JH, Macfarlane GT, Englyst HN. Prebiotic digestion and fermentation. Am J Clin Nutr 2001;73:415S-420S. PubMed
  6. Cadot, P., Kochuyt, A. M., van Ree, R., and Ceuppens, J. L. Oral allergy syndrome to chicory associated with birch pollen allergy. Int.Arch.Allergy Immunol. 2003;131(1):19-24. PubMed
  7. Friis, B., Hjorth, N., Vail, J. T., Jr., and Mitchell, J. C. Occupational contact dermatitis from Cichorium (chicory, endive) and Lactuca (lettuce). Contact Dermatitis 1975;1(5):311-313.
  8. Nemery, B. and Demedts, M. Occupational asthma in a chicory grower. Lancet 3-25-1989;1(8639):672-673. PubMed
  9. Pirson F, Detry B, Pilette C. Occupational rhinoconjunctivitis and asthma caused by chicory and oral allergy syndrome associated with bet v 1-related protein. J Investig Allergol Clin Immunol 2009;19(4):306-10.
  10. Willi R, Pfab F, Huss-Marp J, et al. Contact anaphylaxis and protein contact dermatitis in a cook handling chicory leaves. Contact Dermatitis 2009;60(4):226-7. PubMed
  11. Street RA, Sidana J, Prinsloo G. Cichorium intybus: traditional uses, phytochemistry, pharmacology, and toxicology. Evid Based Complement Alternat Med 2013;2013:579319.
  12. Bonnema AL, Kolberg LW, Thomas W, Slavin JL. Gastrointestinal tolerance of chicory inulin products. J Am Diet Assoc 2010;110(6):865-8. PubMed
  13. Devi Kt R, Sivalingam N. Cichorium intybus attenuates Streptozotocin-induced pancreatic ß-cell damage by inhibiting NF-?B activation and oxidative stress. J Appl Biomed 2020;18(2-3):70-9. PubMed

See these in context on the Chicory monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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