GluDaZyme Ingredients & Drug Interactions
What is this page for?
First and foremost: checking GluDaZyme against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
GluDaZyme is a dietary supplement by Metabolic Maintenance with 10 active ingredients. Its ingredients are commonly taken for lactose intolerance, gas and bloating after dairy, diarrhea from dairy foods.Based on those ingredients, 2 medications have a known interaction with it, the most serious rated moderate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against GluDaZyme by Metabolic Maintenance
Ask about any prescription or over-the-counter medication and we check it for interactions with GluDaZyme by Metabolic Maintenance — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of GluDaZyme by Metabolic Maintenance
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
GluDaZyme contains 14 active ingredients—all digestive enzymes designed to help break down food in your gut. Lactase breaks down lactose (milk sugar); lipase works on fats; cellulase, xylanase, and hemicellulase break down plant fiber; glucoamylase and the amylases break down starches; and multiple proteases (protease I through V) break down proteins.
The formula also includes alpha galactosidase and dipeptidyl peptidase IV (DPP-IV) to help with complex carbohydrates and peptides. The capsule itself is vegetarian cellulose; tapioca maltodextrin is an inactive filler.
Does it work?
Strong evidence
Lactase in this product is effective for lactose intolerance—if you have trouble digesting milk products, it can help. For the other active ingredients—lipase, the proteases, and the rest—the evidence we hold is insufficient to rate whether they work for digestive complaints like indigestion (dyspepsia) or inflammatory bowel conditions.
That means the studies so far haven't been conclusive enough for us to say yes or no.
How safe is it?
Well-documented data
Lactase and lipase are generally well tolerated when used as directed. The proteolytic enzymes are also generally well tolerated for most adults, though digestive upset or allergic reactions are possible.
Rarely, occupational exposure to airborne proteases has caused allergic rhinoconjunctivitis or asthma, but that's not the typical risk from taking a capsule by mouth. For pregnancy: lactase is likely safe, but there's limited data on lipase and proteases in pregnancy—use only if your doctor advises it.
Breastfeeding safety data for lipase and proteases is scant; check with your healthcare provider first. A very rare risk: premature infants given certain recombinant lipases have had gastrointestinal side effects, but that's a neonatal concern, not a general one.
Meds to double-check
Moderate interaction found
No interactions are documented in our data for the ingredients we could check. That said, we weren't able to verify several of the enzymes in this product against our medication database, so if you take any prescription drugs, check them with the tool below or ask your pharmacist before you start.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
GluDaZyme is a multi-enzyme supplement aimed at people with digestive complaints or lactose intolerance. Lactase is proven effective for lactose intolerance; the other enzymes' effectiveness isn't well established in the data we hold.
If you're pregnant, breastfeeding, or have a serious digestive condition, talk with your doctor or pharmacist before using it regularly.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 7 of 14 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 22, 2022.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about GluDaZyme, straight from the product label.
| Brand | Metabolic Maintenance |
|---|---|
| Barcode (UPC) | 838287007050 |
| Net contents | 60 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Sep 22, 2022 |
| DSLD ID | 274036 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for GluDaZyme by Metabolic Maintenance, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Lactase | 0 NP | -- |
| Lipase | 0 NP | -- |
| Cellulase | 0 NP | -- |
| Xylanase | 0 NP | -- |
| Hemicellulase | 0 NP | -- |
| Glucoamylase | 0 NP | -- |
| Protease I | 0 NP | -- |
| Protease II | 0 NP | -- |
| Proprietary Enzyme Blend | 500 mg | -- |
| Alpha Galactosidase | 0 NP | -- |
| Dipeptidyl peptidase (DPP-IV) | 0 NP | -- |
| Protease III | 0 NP | -- |
| Protease IV | 0 NP | -- |
| Protease V | 0 NP | -- |
| Amylase I | 0 NP | -- |
| Amylase II | 0 NP | -- |
Other ingredients: Tapioca Maltodextrin, Vegetarian Cellulose Capsule
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions
Caution: Pregnant or lactating women consult your healthcare professional before taking this product.
Keep tightly closed in a cool, dry place, out of reach of children.
Storage
Keep tightly closed in a cool, dry place, out of reach of children.
Formulation
Egg free Gluten free Free of nuts Dairy free
Manufactured in a GMP Compliant Facility
Enzymatic Breakdown Gluten, dairy, sugar, fat
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Directions: One to two (1-2) capsules before a meal, or as directed by a healthcare professional.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
GluDaZyme by Metabolic Maintenance label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in GluDaZyme by Metabolic Maintenance
These are the 10 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Other (inactive) ingredients: Tapioca Maltodextrin, Vegetarian Cellulose Capsule. These complete the product’s ingredient list but are not active constituents.
GluDaZyme by Metabolic Maintenance Drug Interactions
HelloPharmacist Interaction Report
GluDaZyme by Metabolic Maintenance is a digestive enzyme product, and no interactions are documented in our data for the ingredients we could check.
Lactase, lipase, and the proteolytic enzymes (proteases) in this formula have not shown interaction activity with medications in the monographs we hold.
Read the full breakdown — every affected drug type, severity by severity
We were unable to check several other ingredients in this product—cellulase, xylanase, hemicellulase, glucoamylase, alpha galactosidase, protease III, and both amylase forms—because we don't hold interaction data for them. That doesn't mean they interact with drugs; it means we simply haven't reviewed them against our medication database.
Even though no interactions are documented for the ingredients we evaluated, absence of documented interactions is not a guarantee that none exist. If you take any prescription medications, run them through the checker below or talk with your pharmacist before starting this product.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against GluDaZyme?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in GluDaZyme interact with 2 drugs. Click any drug to see the details.
0 of the 10 ingredients in GluDaZyme interact with drugs. Each result below shows which ingredient is responsible.
WarfarinWarfarin
How Warfarin interacts with GluDaZyme — through 1 ingredient. Tap an ingredient for the detail:
Protease IiiWarfarin (coumadin) Moderate
Interaction Summary
Theoretically, papain might increase the effects and side effects of warfarin.
Read the full Protease Iii + Warfarin interactionWarfarin SodiumCoumadin, Panwarfin, Sofarin
How Warfarin Sodium interacts with GluDaZyme — through 1 ingredient. Tap an ingredient for the detail:
Protease IiiWarfarin (coumadin) Moderate
Interaction Summary
Theoretically, papain might increase the effects and side effects of warfarin.
Read the full Protease Iii + Warfarin Sodium interactionEach ingredient & the kinds of drugs it affects
For each ingredient in GluDaZyme with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Brand information
Manufacturer and brand details for GluDaZyme, from the product label.
Metabolic Maintenance
See all Metabolic Maintenance products- Name
- Metabolic Maintenance
- Street Address
- 601 N Larch Street
- City
- Sisters
- State
- Oregon
- ZipCode
- 97759
- Phone Number
- 800-772-7873
- Web Address
- MetabolicMaintenance.com
GluDaZyme by Metabolic Maintenance: Common Questions
Does GluDaZyme by Metabolic Maintenance interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Will GluDaZyme help with bloating and gas?
Can I take this if I'm lactose intolerant?
Is it safe to take while pregnant?
Could I have an allergic reaction to this?
What exactly are these enzymes?
Can I take this with my other supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if GluDaZyme is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind GluDaZyme’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Lactase
Lactase is a digestive enzyme supplement that helps people who lack enough natural lactase break down lactose, the sugar in milk and dairy. It can reduce gas, bloating, cramping, and diarrhe...
Read the full Lactase monograph → Herb & supplement monographLipase
Lipase is a digestive enzyme that helps your body break down dietary fats. It is well established as part of prescription pancreatic enzyme therapy for people who cannot make enough of their...
Read the full Lipase monograph →Sources & How We Checked
GluDaZyme's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 16 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Lactase 1 reference
- Laukkanen A, Ruoppi P, Remes S, Koistinen T, Mäkinen-Kiljunen S. Lactase-induced occupational protein contact dermatitis and allergic rhinoconjunctivitis. Contact Dermatitis. 2007;57(2):89-93. PubMed
Lipase 1 reference
- Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed
Proteolytic Enzymes (proteases) 3 references
- Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
- Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
- Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed
See these in context on the Proteolytic Enzymes (proteases) monograph →
Papain 11 references
- The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
- Shaw D, Leon C, Kolev S, Murray V. Traditional remedies and food supplements: a 5-year toxicological study (1991-1995). Drug Saf 1997;17:342-56.
- Shuttleworth D, Hill S, Marks R, Connelly DM. Relief of experimentally induced pruritus with a novel eutectic mixture of local anaesthetic agents. Br J Dermatol 1988;119:535-40.
- Mansfield LE, Ting S, Haverly RW, Yoo TJ. The incidence and clinical implications of hypersensitivity to papain in an allergic population, confirmed by blinded oral challenge. Ann Allergy 1985;55:541-3.
- Martin, T., Uhder, K., Kurek, R., Roeddiger, S., Schneider, L., Vogt, H. G., Heyd, R., and Zamboglou, N. Does prophylactic treatment with proteolytic enzymes reduce acute toxicity of adjuvant pelvic irradiation? Results of a double-blind randomized trial PubMed
- Walker-Renard, P. Update on the medicinal management of phytobezoars. Am J Gastroenterol. 1993;88(10):1663-1666.
- Tymoszuk D, Wiszniewska M, Walusiak-Skorupa J. Papain-induced occupational rhinoconjunctivitis and asthma - A case report. Med Pr 2016;67(1):109-12. PubMed
- Soto-Mera MT, López-Rico MR, Filgueira JF, et al. Occupational allergy to papain. Allergy 2000;55(10):983-4. PubMed
- Tarlo SM, Shaikh W, Bell B, et al. Papain-induced allergic reactions. Clin Allergy 1978;8(3):207-15. PubMed
- Baur X, König G, Bencze K, Fruhmann G. Clinical symptoms and results of skin test, RAST and bronchial provocation test in thirty-three papain workers: Evidence for strong immunogenic potency and clinically relevant proteolytic e?ects of airborne papain. C
- Novey HS, Keenan WJ, Fairshter RD, Wells ID, Wilson AF, Culver BD. Pulmonary disease in workers exposed to papain: clinico-physiological and immunological studies. Clin Allergy 1980;10(6):721-31. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC