GlutenEase Extra Strength Ingredients & Drug Interactions
by Enzymedica
What is this page for?
First and foremost: checking GlutenEase Extra Strength against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
GlutenEase Extra Strength is a dietary supplement by Enzymedica with 4 active ingredients. Its ingredients are commonly taken for digestion and bloating, muscle soreness and exercise recovery, inflammation and swelling.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of GlutenEase Extra Strength by Enzymedica
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
GlutenEase Extra Strength contains four active enzymes. Protease is a proteolytic enzyme that breaks down proteins; the other three — Amylase, Glucoamylase, and Dipeptidyl Peptidase-IV — are designed to help break down carbohydrates and peptides related to gluten.
The capsule also contains cellulose and water as inactive ingredients.
Does it work?
Couldn't assess
We hold no effectiveness ratings in our data for any of the four active ingredients in this product, so we cannot tell you whether the evidence supports its use for gluten digestion or any other purpose based on the information available to us.
How safe is it?
Well-documented data
Protease is generally well tolerated in most adults, though digestive upset or allergic reactions can occur in some people. The safety data advises against protease use during pregnancy unless prescribed by a doctor.
During breastfeeding, there is little safety information available, so use is not recommended without medical advice first. Rarely, people exposed to proteases (such as in occupational settings or through detergent products) have reported allergic reactions including allergic rhinoconjunctivitis or asthma.
We do not hold safety information on file for Amylase, Glucoamylase, or Dipeptidyl Peptidase-IV during pregnancy or breastfeeding.
Meds to double-check
No known interactions
No interactions are documented in our data for the ingredients we could check. However, we were unable to check Amylase, Glucoamylase, and Dipeptidyl Peptidase-IV, so please search your specific medications using the tool on this page to be safe.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. No medication interactions are currently documented, and safety information is well characterized.
This enzyme blend is generally well tolerated if you're looking for digestive support with gluten-containing meals. If you're pregnant, breastfeeding, or have a history of allergic reactions to enzyme products, talk with your pharmacist or doctor before starting.
Because we couldn't check all the ingredients against your medications, a quick search of your drug list here is a smart step.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated May 21, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about GlutenEase Extra Strength, straight from the product label.
| Brand | Enzymedica |
|---|---|
| Barcode (UPC) | 670480120118 |
| Net contents | 60 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | May 21, 2025 |
| DSLD ID | 328966 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for GlutenEase Extra Strength by Enzymedica, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Amylase | 0 NP | -- |
| Protease | 0 NP | -- |
| Glucoamylase | 0 NP | -- |
| Dipeptidyl Peptidase-IV | 0 NP | -- |
Other ingredients: Cellulose, Water
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Formulation
Many people have difficulty digesting gluten and casein proteins commonly found in carbohydrates, resulting in discomforts like occasional gas and bloating. Even those on gluten-free/casein-free diets may experience difficulties due to cross-contamination from offending foods.
No fillers added
Made in USA with global ingredients
Non GMO
Digestive
Most advanced Gluten and Casein Formula Optimizes digestion of foods containing gluten and casein Provides enzyme support for gluten-free/casein-free diets
Vegan & Kosher
Contains no: Gluten, milk, casein, soy, egg, artificial colors or flavors
Formula
GlutenEase Extra Strength contains Protease Thera-Blend (G2) enzymes along with DPP-IV activity for providing more than double the digesting power for foods containing gluten and casein compared to GlutenEase. Starch-digesting amylase enzymes assist in the digestion of the carbohydrate portion of grains, such as wheat, which contain gluten.
Thera-blend enzymes are comprised of multiple variants which are blended to work synergistically throughout the broad pH range of the human body.
Vegan & Kosher
Suggested/Recommended/Usage/Directions
Recommended Use: 1 capsule with each meal containing gluten or casein. More may be taken as needed.
Precautions
This product is not intended to replace a gluten-free diet for individuals with Celiac Disease.
Do not use if safety seal is broken or missing.
Please keep out of reach of children
Brand IP Statement(s)
Enzymedica The Enzyme Experts
General Statements
Most Advanced
#1 Selling Enzyme Brand
FDA Statement of Identity
Dietary Supplement
Storage
Keep closed in dry place; avoid excessive heat.
Seals/Symbols
K Parve (Kosher) #K1840
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
GlutenEase Extra Strength by Enzymedica label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in GlutenEase Extra Strength by Enzymedica
These are the 4 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Amylase
Protease
No knowninteractions
Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), tr...
Protease monograph & interactionsGlucoamylase
Dipeptidyl Peptidase-IV
Other (inactive) ingredients: Cellulose, Water. These complete the product’s ingredient list but are not active constituents.
GlutenEase Extra Strength by Enzymedica Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in GlutenEase Extra Strength. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for GlutenEase Extra Strength, from the product label.
Enzymedica
See all Enzymedica products- Name
- Enzymedica, Inc.
- Street Address
- 771 Commerce Drive
- City
- Venice
- State
- FL
- ZipCode
- 34292-1731
- Phone Number
- 1-888-918-1118
- Web Address
- www.enzymedica.com
GlutenEase Extra Strength by Enzymedica: Common Questions
Does GlutenEase Extra Strength by Enzymedica interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take GlutenEase Extra Strength if I'm pregnant?
Is it safe to breastfeed while taking this?
What does protease do in this formula?
Can protease cause allergic reactions?
Does this product have any fillers?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if GlutenEase Extra Strength is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind GlutenEase Extra Strength’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
GlutenEase Extra Strength's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 3 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Proteolytic Enzymes (proteases) 3 references
- Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
- Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
- Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed
See these in context on the Proteolytic Enzymes (proteases) monograph →
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC