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Dietary supplement

Goat's Rue Ingredients & Drug Interactions

by Motherlove

Goat's Rue label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Goat's Rue against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Goat's Rue is a dietary supplement by Motherlove with 1 active ingredient. Its ingredients are commonly taken for boosting breast milk supply, blood sugar support, traditional digestive remedy.Based on those ingredients, 122 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Goat's Rue. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Goat's Rue by Motherlove

Ask about any prescription or over-the-counter medication and we check it for interactions with Goat's Rue by Motherlove — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Goat's Rue by Motherlove

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: goat's rue, a traditional herbal supplement. Motherlove's liquid form includes deionized water and alcohol as inactive ingredients to preserve and deliver the herb.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Goat's Rue's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: boost breast milk supply for breastfeeding.
  • We looked for evidence on: Lactation, Milk supply, Insufficient lactation, Galactagogue.
  • The closest evidence on file: Goat's Rue is rated "Insufficient Reliable Evidence To Rate" for Lactation (Natural Medicines).

The data we hold rates goat's rue for lactation support as having insufficient reliable evidence. While it's traditionally used to help with milk supply, the research backing that use isn't conclusive enough for us to rate it as proven effective.

If you're considering it for that purpose, talk with a lactation consultant or your healthcare provider about what the current evidence actually supports.

The evidence, ingredient by ingredient Goat's Rue

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 0 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Safety data on goat's rue supplements is limited in humans. The fresh plant itself can be toxic, so the quality and safety of commercial supplements vary—use only under professional guidance.

The supplement is not recommended during pregnancy due to lack of safety data. Because well-controlled human studies are sparse, unexpected side effects are possible even if none are documented in our files.

Side effects, ingredient by ingredient Goat's Rue

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Goat's Rue.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 122 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take any blood thinner or antiplatelet medication—including aspirin, clopidogrel (Plavix), enoxaparin (Lovenox), heparin, ticlopidine, dalteparin (Fragmin), or similar drugs—check with your pharmacist before using this product. There's a moderate risk goat's rue could increase your bleeding risk when combined with these medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and some safety-information gaps remain.

Goat's rue is traditionally used to support milk supply, but evidence is thin and safety data are limited. If you take blood thinners or antiplatelet drugs, this one's off limits without your doctor's okay.

Talk to your pharmacist or healthcare provider before starting, especially if you're pregnant, breastfeeding, or on any medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 24, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Goat's Rue, straight from the product label.

Brand Motherlove
Barcode (UPC) 759160540023
Net contents 2 Fluid Ounce(s); 59 mL
Market status On market
Date entered into DSLD Jul 24, 2025
DSLD ID 334837
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Kosher, Organic, Adult Female (18 - 50 Years), Lactating
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Goat's Rue by Motherlove, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Pregnant and Lactating
Minimum serving Sizes:
1 mL
Maximum serving Sizes:
1 mL
Servings per container
59
UPC/BARCODE
759160540023
IngredientAmount% DV
Goat's Rue950 mg--

Other ingredients: deionized Water, Alcohol

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use Take 1 dropper (1 mL) 4 to 6 times throughout the day or as recommended by your healthcare practitioner. Shake before using.

Formulation

Formulated for moms who did not experience an increase in breast size, plan to adoptive feed, or are trying to relactate.

Breastfeeding

USDA Organic Certified Organic by Oregon Tilth

Made in the USA with imported ingredients

Precautions

Discuss product use with a healthcare practitioner. Discontinue use if side effects appear. Sealed for your protection.

Any ingested food has the potential for an allergic reaction.

Keep out of reach of children.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formula

Single-herb goat's rue supplement for breastfeeding moms

Herbal Supplement

KOF-K (Kosher) Parve K-1604

Seals/Symbols

USDA Organic Certified B Corporations KOF-K (Kosher) Parve K-1604

General Statements

Women Owned

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Goat's Rue by Motherlove label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Goat's Rue label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Goat's Rue by Motherlove

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 mL Dosage formLiquid Servings per container59 Amounts shown are per serving.

Goat's Rue

Interacts with
122 drugs
950 mg per serving

Goat's rue is a traditional herb most often used by nursing parents to try to increase milk supply, and it has a historical link to diabetes research....

Goat's Rue monograph & interactions

Other (inactive) ingredients: Deionized Water, Alcohol. These complete the product’s ingredient list but are not active constituents.

Interaction report

Goat's Rue by Motherlove Drug Interactions

Want to check YOUR meds against Goat's Rue?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
122Drugs
122 Moderate

Ingredients driving the most interactions

Goat's Rue 122

Individual Drug Interactions

The ingredients in Goat's Rue interact with 122 drugs. Click any drug to see the details.

1 of the 1 ingredient in Goat's Rue interact with drugs. Each result below shows which ingredient is responsible. Goat's Rue

Each ingredient & the kinds of drugs it affects

For each ingredient in Goat's Rue with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Goat's Rue1 drug type · 122 drugs

Anticoagulant/Antiplatelet Drugs

Laboratory research suggests that goat's rue extract can inhibit platelet aggregation. Theoretically, goat's rue might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs. Some anticoagulant or antiplatelet drugs include aspirin, clopidogrel (Plavix), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, ticlopidine (Ticlid), warfarin (Coumadin), and others.

Likelihood Possible Evidence D
Goat's Rue full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Goat's Rue, from the product label.

Motherlove

See all Motherlove products
Name
Motherlove Herbal Company
City
Fort Collins
State
CO
ZipCode
80524
Phone Number
970-493-2892
Web Address
motherlove.com
Pharmacist Counseling Corner

Goat's Rue by Motherlove: Common Questions

Does Goat's Rue by Motherlove interact with any medications?
Yes. Based on its ingredients, Goat's Rue has a known interaction with 122 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Goat's Rue contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is goat's rue proven to help with milk supply?
The evidence we have is insufficient to rate it as proven effective for lactation. While it's used traditionally for that purpose, the research isn't strong enough yet. If you're breastfeeding and thinking about using it, talk with a lactation consultant or your healthcare provider.
Can I take this while pregnant?
No—there isn't enough safety data, so it's best avoided during pregnancy. Talk with your doctor if you're pregnant or planning to become pregnant and interested in herbal support.
What's in this liquid besides goat's rue?
The inactive ingredients are deionized water and alcohol, which preserve the herb and make it easy to take as a liquid.
Are there any side effects I should know about?
No adverse effects are documented in our data, but human safety studies on this supplement are limited. The fresh plant can be toxic, so quality and safety of supplements vary—use only under professional guidance.
Can I take this if I'm on aspirin or another blood thinner?
No—goat's rue can interfere with how blood thinners work and increase bleeding risk. If you take aspirin, clopidogrel (Plavix), enoxaparin (Lovenox), heparin, or any similar medication, check with your pharmacist before using this product.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Goat's Rue is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Goat's Rue label
Go deeper

The Full Monographs Behind Goat's Rue’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Goat's Rue

Interacts with 122 drugs

Goat's rue is a traditional herb most often used by nursing parents to try to increase milk supply, and it has a historical link to diabetes research. Solid human evidence for either use is...

Read the full Goat's Rue monograph →
Sources

Sources & How We Checked

Goat's Rue's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Goat's Rue 6 references
  1. Atanasov AT. Effect of Galega officinalis L. extract on platelet aggregation in rats. J Herbs Spices Med Plants 1995;3:71-6.
  2. Atanasov, A. T. and Spasov, V. Inhibiting effect of desalted extract from Galega officinalis L. on platelet aggregation. Folia Med.(Plovdiv.) 1999;41(1):46-50.
  3. Atanasov, A. T. and Spasov, V. Inhibiting and disaggregating effect of gel-filtered Galega officinalis L. herbal extract on platelet aggregation. J.Ethnopharmacol. 2000;69(3):235-240. PubMed
  4. Atanasov, A. T. and Tchorbanov, B. Anti-platelet fraction from Galega officinalis L. inhibits platelet aggregation. J.Med.Food 2002;5(4):229-234.
  5. Atanasov, A. T. and Tchorbanov, B. J. Antiplatelet aggregation activity of a fraction isolated from Galega officinalis L. J Herbs Spices Medicinal Plant 2002;10(2):63-71.
  6. Salatino S, Giacomelli L, Carnevali I, Giacomelli E. The role of natural galactagogues during breast feeding: focus on a Galega officinalis based food supplement. Minerva Pediatr. 2017 Dec;69(6):531-537. PubMed

See these in context on the Goat's Rue monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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