Interactions on record — worth a quick check against your medications. Based on 5 of 18 ingredients. Check your meds →
Dietary supplement

Good Zymes Ingredients & Drug Interactions

by Vitality For Life

Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Good Zymes is a dietary supplement by Vitality For Life with 18 active ingredients. Its ingredients are commonly taken for inflammation and swelling, sinus and nasal congestion, digestion support.Based on those ingredients, 141 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Bromelain. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Good Zymes by Vitality For Life

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 18 active ingredients.

Good Zymes contains 18 active ingredients, all digestive enzymes designed to break down different food components. Bromelain breaks down protein; Lipase tackles fats; Lactase handles milk sugar; and Cellulase, Amylase, and others work on fiber and carbohydrates.

The blend also includes Protease enzymes (Protease 4.5, Protease 6, and Neutral Protease, Bacterial) for additional protein digestion, plus Phytase and other specialized enzymes for harder-to-digest plant compounds. The capsule also contains inactive ingredients — Hydroxypropyl Methylcellulose, Microcrystalline Cellulose, and Medium Chain Triglyceride — which are fillers and binders that help hold the formula together.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Multi-enzyme digestive aid.
  • We looked for evidence on: Dyspepsia, Lactose intolerance, Exercise-induced muscle soreness, Postoperative swelling, Allergic rhinitis (hay fever), Rhinosinusitis — and 3 related terms.
  • The strongest evidence on file: Lactase is rated "Effective" for Lactose intolerance (Natural Medicines).
  • Also on file: Lipase is rated "Insufficient Reliable Evidence To Rate" for Dyspepsia.
  • Also on file: Bromelain is rated "Insufficient Reliable Evidence To Rate" for Allergic rhinitis (hay fever), Exercise-induced muscle soreness, Rhinosinusitis, Postoperative swelling.

The evidence supporting these enzymes is limited. Lactase is effective for lactose intolerance — that one's straightforward.

For the others — Bromelain for hay fever, burns, or cancer; Lipase for indigestion or inflammatory bowel disease; Phytase for iron or zinc status; and the proteolytic enzymes overall — we don't have enough reliable evidence to say whether they work. Most fall into the "insufficient evidence" category, meaning the research just isn't there yet.

The evidence, ingredient by ingredient Bromelain Lipase Lactase Phytase Proteolytic Enzymes (proteases)

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 5 of the 5 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 5 of 5.
  • General safety write-ups exist for 5 of 5.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Bromelain is generally well tolerated short-term when taken by mouth, though some people experience diarrhea, gas, stomach upset, or headache. Rare allergic reactions (including asthma or throat swelling if inhaled) can occur.

It's best avoided in pregnancy and breastfeeding because safety data are insufficient. The proteolytic enzymes (the Protease ingredients) are generally well tolerated but may cause digestive upset or allergic reactions in sensitive people.

Safety in pregnancy hasn't been established, so they should be avoided unless prescribed. Breastfeeding safety data are limited — check with your doctor first.

Lactase is likely safe in pregnancy and acts only in the gut, though pregnancy and breastfeeding data for Lipase and Phytase are either limited or absent, so talk with your doctor about regular use.

Side effects, ingredient by ingredient Bromelain Lipase Lactase Phytase Proteolytic Enzymes (proteases)

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 5 matched ingredients can interact with medications — Bromelain.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 141 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you're on blood thinners or antiplatelet medications (warfarin, aspirin, clopidogrel, dabigatran, and others), the Bromelain here may increase your bleeding risk — Moderate severity, so definitely discuss this with your pharmacist. If you take tetracycline antibiotics like doxycycline, mention it too — Minor risk, but worth knowing.

For all other medications you're on, run them through the checker on this page to be sure.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This is a broad-spectrum digestive enzyme supplement, best suited for people with occasional bloating, gas, or trouble digesting certain foods — or for those with low stomach acid or enzyme production. If you take blood thinners, antiplatelet drugs, or tetracycline antibiotics, check with your pharmacist before starting.

Pregnant or breastfeeding? Talk to your doctor first; safety data are thin for most of these.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 7 of 18 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 24, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Good Zymes, straight from the product label.

Brand Vitality For Life
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Jul 24, 2025
DSLD ID 331647
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Kosher
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Good Zymes by Vitality For Life, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
60
IngredientAmount% DV
Amylase0 NP--
Bromelain0 NP--
Lipase0 NP--
Lactase0 NP--
Cellulase0 NP--
Peptidase0 NP--
Invertase0 NP--
Glucoamylase0 NP--
Xylanase0 NP--
Pectinase0 NP--
Beta-Glucanase0 NP--
Phytase0 NP--
Hemicellulase0 NP--
Protease 4.50 NP--
Protease 60 NP--
Alpha-Galactosidase0 NP--
Acid Maltase0 NP--
Neutral Protease, Bacterial0 NP--

Other ingredients: Hydroxypropyl Methylcellulose, Microcrystalline Cellulose, Medium Chain Triglyceride

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Multi-enzyme digestive aid

Enjoy the food you love without the worry of digestive discomfort. Digestive aid: Helps break down and digest proteins, carbohydrates, dairy, fats, sugars, starches, cellulose, beans, and fibers Nutrient Boost: Helps increase nutrient availability and accessibility during digestion Soothing relief: Helps relieve occasional gas, bloating, and indigestion

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Any time Directions: Take one capsule right before eating a meal. Do not take on an empty stomach. Two capsules may be taken if desired.

Precautions

Consult your physician before taking this product if you are pregnant, planning to become pregnant, nursing, under a doctor's care, taking any medications, or administering to children under the age of 18. Keep out of reach of children.

Consult your physician before taking this product if you are pregnant, planning to become pregnant, nursing, under a doctor's care, taking any medications, or administering to children under the age of 18.

Tamper-evident inner seal; if broken, do not accept.

Made in a facility that also processes dairy, shellfish, tree nuts, and soy.

Storage

Store in a cool, dry, dark place.

Formula

18 unique digestive enzymes

Star-K (Kosher)

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Seals/Symbols

Star-K (Kosher)

See for yourself

Good Zymes by Vitality For Life label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Good Zymes by Vitality For Life

These are the 18 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Amylase

0 NP per serving

Bromelain

Interacts with
141 drugs
0 NP per serving

Bromelain is a group of protein-digesting enzymes from pineapple that people take mainly for inflammation, swelling, and sinus problems. Some early st...

Bromelain monograph & interactions

Lipase

No known
interactions
0 NP per serving

Lipase is a digestive enzyme that helps your body break down dietary fats. It is well established as part of prescription pancreatic enzyme therapy fo...

Lipase monograph & interactions

Lactase

No known
interactions
0 NP per serving

Lactase is a digestive enzyme supplement that helps people who lack enough natural lactase break down lactose, the sugar in milk and dairy. It can red...

Lactase monograph & interactions

Cellulase

0 NP per serving

Peptidase

0 NP per serving

Invertase

0 NP per serving

Glucoamylase

0 NP per serving

Xylanase

0 NP per serving

Pectinase

0 NP per serving

Beta-Glucanase

0 NP per serving

Phytase

No known
interactions
0 NP per serving

Phytase is an enzyme that breaks down phytic acid (phytate) found in grains, beans, nuts, and seeds, which can free up minerals like iron, zinc, and c...

Phytase monograph & interactions

Hemicellulase

0 NP per serving

Protease 4.5

No known
interactions
0 NP per serving

Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), tr...

Protease 4.5 monograph & interactions

Protease 6

No known
interactions
0 NP per serving

Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), tr...

Protease 6 monograph & interactions

Alpha-Galactosidase

0 NP per serving

Acid Maltase

0 NP per serving

Neutral Protease, Bacterial

No known
interactions
0 NP per serving

Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), tr...

Neutral Protease, Bacterial monograph & interactions

Other (inactive) ingredients: Hydroxypropyl Methylcellulose, Microcrystalline Cellulose, Medium Chain Triglyceride. These complete the product’s ingredient list but are not active constituents.

Interaction report

Good Zymes by Vitality For Life Drug Interactions

Want to check YOUR meds against Good Zymes?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
141Drugs
122 Moderate 19 Minor

Ingredients driving the most interactions

Bromelain 141

Each ingredient & the kinds of drugs it affects

For each ingredient in Good Zymes with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Bromelain2 drug types · 141 drugs

Anticoagulant/Antiplatelet Drugs

Bromelain may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
There is one case report of a patient experiencing minor bruising while taking bromelain with naproxen. Bromelain is thought to have antiplatelet activity. Whether this interaction is of concern with topical bromelain is unclear. Interference with coagulation of burn wounds has been reported in a patient receiving bromelain-based enzymatic debridement. However, observational research has found that topical bromelain debridement is not associated with increases or decreases in laboratory markers of coagulation when compared with surgical debridement.

Likelihood Possible Evidence D
Tetracycline Antibiotics

Theoretically, bromelain might increase levels of tetracycline antibiotics.
Laboratory research suggests that bromelain might increase the absorption of tetracycline antibiotics. However, a study in healthy adults reported no difference in tetracycline plasma levels when a 500 mg dose was taken with or without bromelain 80 mg.

Likelihood Possible Evidence B
The maker

Brand information

Manufacturer and brand details for Good Zymes, from the product label.

Vitality For Life

See all Vitality For Life products
Name
Vitality For Life
Pharmacist Counseling Corner

Good Zymes by Vitality For Life: Common Questions

Does Good Zymes by Vitality For Life interact with any medications?
Yes. Based on its ingredients, Good Zymes has a known interaction with 141 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Good Zymes contains 18 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does Good Zymes actually help with digestion?
Lactase in the formula definitely works for lactose intolerance if that's your issue. For the other enzymes — breaking down fats, proteins, fiber, and carbs — we don't have enough solid research to say whether the supplement doses help most people. The formula is aimed at supporting digestion, but individual results vary.
Can I take Good Zymes if I'm pregnant?
Bromelain should be avoided in pregnancy — safety data aren't strong enough. Lactase is likely safe. Lipase, Phytase, and the Protease enzymes don't have reliable safety information for pregnancy, so it's best to skip this supplement unless your doctor says it's okay.
Is it safe while breastfeeding?
Bromelain should be avoided — safety while breastfeeding is unknown. Lactase is likely safe and acts only in your gut. For Lipase, Phytase, and the Protease enzymes, there's not enough data, so check with your doctor or pharmacist before use.
What are the most common side effects?
Bromelain may cause diarrhea, gas, stomach upset, or headache. The Protease enzymes can cause digestive upset or, rarely, allergic reactions. Most people tolerate the formula fine, but if you have a sensitive stomach or a history of enzyme allergies, go slow and watch for symptoms.
Does this have any fillers or 'other' ingredients?
Yes — the capsule contains Hydroxypropyl Methylcellulose, Microcrystalline Cellulose, and Medium Chain Triglyceride as inactive ingredients. These are binders and fillers that help make the capsule work; they're standard in most supplements.
Can I take this with my blood pressure or blood thinner medication?
If you take blood thinners (like warfarin) or antiplatelet drugs (like aspirin or clopidogrel), the Bromelain in Good Zymes may increase your bleeding risk. Talk to your pharmacist before starting — don't just add it on your own.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Good Zymes is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Good Zymes label
Go deeper

The Full Monographs Behind Good Zymes’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Good Zymes's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 31 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Bromelain 19 references
  1. Nettis E, Napoli G, Ferrannini A, Tursi A. IgE-mediated allergy to bromelain. Allergy 2001;56:257-8. PubMed
  2. Taussig SJ, Batkin S. Bromelain, the enzyme complex of pineapple (Ananas comosus) and its clinical application. An update. J Ethnopharmacol 1988;22:191-203.. PubMed
  3. Bradbrook ID, Morrison PJ, Rogers HJ. The effect of bromelain on the absorption of orally administered tetracycline. Br J Clin Pharmacol 1978;6:552-4. PubMed
  4. Bush TM, Rayburn KS, Holloway SW, et al. Adverse interactions between herbal and dietary substances and prescription medications: a clinical survey. Altern Ther Health Med 2007;13:30-5.
  5. Brien S, Lewith G, Walker AF, et al. Bromelain as an adjunctive treatment for moderate-to-severe osteoarthritis of the knee: a randomized placebo-controlled pilot study. QJM 2006;99:841-50. PubMed
  6. Mori S, Ojima Y, Hirose T, et al. The clinical effect of proteolytic enzyme containing bromelain and trypsin on urinary tract infection evaluated by double blind method. Acta Obstet Gynaecol Jpn 1972;19:147-53.
  7. Glaser D, Hilberg T. The influence of bromelain on platelet count and platelet activity in vitro. Platelets 2006;17:37-41. PubMed
  8. Heinicke R M, van der Wal L, Yokoyama M. Effect of bromelain (Ananase) on human platelet aggregation. Experientia 1972;28:844-5. PubMed
  9. Gailhofer, G., Wilders-Truschnig, M., Smolle, J., and Ludvan, M. Asthma caused by bromelain: an occupational allergy. Clin Allergy 1988;18(5):445-450. PubMed
  10. Mattei, O., Fabri, G., and Farina, G. [Occupational health experience regarding four cases of asthma due to bromelain (author's transl)]. Medicina del Lavoro 1979;70(5):404-409.
  11. Galleguillos, F. and Rodriguez, J. C. Asthma caused by bromelin inhalation. Clin Allergy 1978;8(1):21-24. PubMed
  12. Perez-Camo I, Quirce S, Duran MA, and et al. Latex allergy: evidence of cross-reactivity with papain and bromelain [abstract]. Allergy 1996;51(suppl 31):48.
  13. Martin GJ, Ehrenreich J, and Asbell N. Bromelain: pineapple proteases with anti-edema activity. Exp Med Surg 1962;20:227-247.
  14. Kasemsuk T, Saengpetch N, Sibmooh N, Unchern S. Improved WOMAC score following 16-week treatment with bromelain for knee osteoarthritis. Clin Rheumatol. 2016 Oct;35(10):2531-40. PubMed
  15. Kutlu Ö, DemirbaS A, Elmas ÖF, Güvenç U, Metin A. Fixed drug eruption: a new side effect of bromelain. Contact Dermatitis 2020. Online ahead of print. PubMed
  16. Shoham Y, Shapira E, Haik J, et al. Bromelain-based enzymatic debridement of chronic wounds: Results of a multicentre randomized controlled trial. Wound Repair Regen 2021;29(6):899-907. PubMed
  17. Pfister P, Garcia Wendel PD, Kim BS, et al. Coagulation side effects of enzymatic debridement in burned patients. Burns 2022. PubMed
  18. Hasham S, Riyat H, Fletcher A, O'Boyle CP, Alexander S. To bleed or not to bleed? Case series and discussion of haemorrhage risk with enzymatic debridement in burn injuries. Scars Burn Heal 2023;9:20595131231168333. PubMed
  19. Leelakanok N, Petchsomrit A, Janurai T, Saechan C, Sunsandee N. Efficacy and safety of bromelain: A systematic review and meta-analysis. Nutr Health 2023. PubMed

See these in context on the Bromelain monograph →

Lipase 1 reference
  1. Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed

See these in context on the Lipase monograph →

Lactase 1 reference
  1. Laukkanen A, Ruoppi P, Remes S, Koistinen T, Mäkinen-Kiljunen S. Lactase-induced occupational protein contact dermatitis and allergic rhinoconjunctivitis. Contact Dermatitis. 2007;57(2):89-93. PubMed

See these in context on the Lactase monograph →

Phytase 7 references
  1. Lei XG, Weaver JD, Mullaney E, Ullah AH, Azain MJ. Phytase, a new life for an "old" enzyme. Annu Rev Anim Biosci. 2013;1:283-309. PubMed
  2. Smuts CM, Matsungo TM, Malan L, et al. Effect of small-quantity lipid-based nutrient supplements on growth, psychomotor development, iron status, and morbidity among 6- to 12-mo-old infants in South Africa: a randomized controlled trial. Am J Clin Nutr. 2 PubMed
  3. van Heemst RC, Sander I, Rooyackers J, et al. Hypersensitivity pneumonitis caused by occupational exposure to phytase. Eur Respir J. 2009;33(6):1507-9. PubMed
  4. Baur X, Melching-Kollmuss S, Koops F, Strassburger K, Zober A. IgE-mediated allergy to phytase -- a new animal feed additive. Allergy. 2002;57(10):943-5. PubMed
  5. Doekes G, Kamminga N, Helwegen L, Heederik D. Occupational IgE sensitisation to phytase, a phosphatase derived from Aspergillus niger. Occup Environ Med. 1999;56(7):454-9. PubMed
  6. Brnic M, Hurrell RF, Songré-Ouattara LT, et al. Effect of phytase on zinc absorption from a millet-based porridge fed to young Burkinabe children. Eur J Clin Nutr. 2017;71(1):137-141. PubMed
  7. Koshy JC, Sharabi SE, Feldman EM, Hollier LH Jr, Patrinely JR, Soparkar CN. Effect of dietary zinc and phytase supplementation on botulinum toxin treatments. J Drugs Dermatol. 2012;11(4):507-12.

See these in context on the Phytase monograph →

Proteolytic Enzymes (proteases) 3 references
  1. Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
  2. Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
  3. Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed

See these in context on the Proteolytic Enzymes (proteases) monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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