GPLC 750 mg Ingredients & Drug Interactions
What is this page for?
First and foremost: checking GPLC 750 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
GPLC 750 mg is a dietary supplement by Jarrow Formulas with 1 active ingredient. Its ingredients are commonly taken for sleep quality and insomnia, relaxation, cognitive function.Based on those ingredients, 1 medication has a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Glycine Propionyl-L-Carnitine HCl. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against GPLC 750 mg by Jarrow Formulas
Ask about any prescription or over-the-counter medication and we check it for interactions with GPLC 750 mg by Jarrow Formulas — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of GPLC 750 mg by Jarrow Formulas
Four independent checks of what is known — a summary of the available information, not a grade of the product itself.
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
The stated purpose hasn't been mapped to our evidence data yet.
Why this rating?
- We haven't mapped this product's purpose to our evidence data yet — it'll be graded on the next content refresh.
Every active ingredient lists its own amount on the label.
Why this rating?
- The label discloses an exact amount for 1 of its 1 active ingredient.
- No proprietary blends here — you can verify the dose of every single component.
The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.
Why this rating?
- 1 of the 1 matched ingredient can interact with medications — Glycine.
- The most serious interaction on file is rated Moderate.
- For scale: 1 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.
Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.
Why this rating?
- We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
- Pregnancy & breastfeeding safety ratings cover 1 of 1.
- General safety write-ups exist for 1 of 1.
- Remember: this measures how much safety information exists. Thin data is not the same as being safe.
HelloPharmacist summaryFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Nov 21, 2019.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about GPLC 750 mg, straight from the product label.
| Brand | Jarrow Formulas |
|---|---|
| Barcode (UPC) | 790011020127 |
| Net contents | 60 Tablet(s) |
| Market status | Off market |
| Date entered into DSLD | Nov 21, 2019 |
| DSLD ID | 201009 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Tablet Or Pill |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for GPLC 750 mg by Jarrow Formulas, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Glycine Propionyl-L-Carnitine HCl | 750 mg | -- |
Other ingredients: Calcium Phosphate, Cellulose, Stearic Acid, Silicon Dioxide, Magnesium Stearate, food-grade Coating
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Usage: Take 1 tablet per day on an empty stomach or as directed by your qualified healthcare professional.
Precautions
Note: If you have a medical condition, are pregnant, lactating, trying to conceive, under the age of 18, or taking medications, consult your healthcare professional before using this product.
Note: If you have a medical condition, are pregnant, lactating, trying to conceive, under the age of 18, or taking medications, consult your healthcare professional before using this product.
Keep out of the reach of children.
Formula
GPLC is a propionyl ester of L-carnitine (PLC) that includes a glycine component. Compared with other forms of carnitine, PLC exhibits a special affinity for muscle tissues, including those of the heart and skeletal muscles. GPLC is a powerful antioxidant that scavenges free radicals - protecting against lipid peroxidation - assists in energy production - contributing to proper carbohydrate metabolism, improved muscle function, and reduced lactic acid buildup during low-oxygen conditions, such as exercise - and provides powerful support for peripheral arterial blood flow.
Glycine Propionyl-L-Carnitine HCl
Brand IP Statement(s)
AminoCarnitines such as GlycoCarn, ArginoCarn and L-Tauro are manufactured by Sigma-tau HealthScience under USA production patent # 6703042 and Worldwide production patent EP1202956.
Glycine Propionyl-L-Carnitine HCl is protected by U.S. Patent # 6,703,042 B1.
AminoCarnitines Sigma-tau HealthScience, LLC
2017 Jarrow Formulas
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
General Statements
Now a tablet Supports Arterial Blood Flow
FDA Statement of Identity
Dietary Supplement
Seals/Symbols
Vegan V Easy Solv
Non GMO Non Genetically Modified
Formulation
No wheat, gluten, soybeans, dairy, egg, fish/shellfish, or peanuts/tree nuts.
Suitable for Vegetarians/Vegans.
Storage
Store in a cool, dry place. Do not refrigerate.
General
10117GPLC PROD # 102012
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
GPLC 750 mg by Jarrow Formulas label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in GPLC 750 mg by Jarrow Formulas
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container60 Amounts shown are per serving.
Glycine Propionyl-L-Carnitine HCl
Interacts with1 drug
Glycine is a non-essential amino acid your body makes on its own and that also appears in protein-rich foods. It is most studied for improving sleep q...
Glycine Propionyl-L-Carnitine HCl monograph & interactionsOther (inactive) ingredients: Calcium Phosphate, Cellulose, Stearic Acid, Silicon Dioxide, Magnesium Stearate, Food-grade Coating. These complete the product’s ingredient list but are not active constituents.
GPLC 750 mg by Jarrow Formulas Drug Interactions
GPLC 750 mg contains a single active ingredient, and it has known interactions with 1 medication. Here’s the picture, then you can look up your own drug.
Want to check YOUR meds against GPLC 750 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in GPLC 750 mg interact with 1 drug. Click any drug to see the details.
1 of the 1 ingredient in GPLC 750 mg interact with drugs. Each result below shows which ingredient is responsible. Glycine Propionyl-L-Carnitine HCl
ClozapineClozaril, Versacloz
How Clozapine interacts with GPLC 750 mg — through 1 ingredient. Tap an ingredient for the detail:
Glycine Propionyl-l-carnitine HclClozapine (clozaril) Moderate
Interaction Summary
Theoretically, glycine might decrease the effectiveness of clozapine.
Read the full Glycine Propionyl-l-carnitine Hcl + Clozapine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in GPLC 750 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Glycine Propionyl-L-Carnitine HCl
Clozapine (Clozaril)
Theoretically, glycine might decrease the effectiveness of clozapine.
One small clinical study in patients with schizophrenia shows that adding glycine to clozapine therapy worsens symptoms of schizophrenia when compared with clozapine alone. The mechanism of this interaction is unclear.
Brand information
Manufacturer and brand details for GPLC 750 mg, from the product label.
Jarrow Formulas
See all Jarrow Formulas products- Name
- Jarrow Formulas Superior Nutrition and Formulation
- Street Address
- P.O. Box 35994
- City
- Los Angeles
- State
- CA
- ZipCode
- 90035-4317
- Web Address
- www.Jarrow.com
GPLC 750 mg by Jarrow Formulas: Common Questions
Does GPLC 750 mg by Jarrow Formulas interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if GPLC 750 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind GPLC 750 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
GPLC 750 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 5 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Glycine 5 references
- Heresco-Levy U, Javitt DC, Ermilov M, et al. Efficacy of high-dose glycine in the treatment of enduring negative symptoms of schizophrenia. Arch Gen Psychiatry 1999;56:29-36.. PubMed
- Potkin SG, Jin Y, Bunney BG, Costa J, Gulasekaram B. Effect of clozapine and adjunctive high-dose glycine in treatment-resistant schizophrenia. Am J Psychiatry 1999;156:145-7.. PubMed
- Gusev EI, Skvortsova VI, Dambinova SA, et al. Neuroprotective effects of glycine for therapy of acute ischaemic stroke. Cerebrovasc Dis 2000;10:49-60. PubMed
- Inagawa K, Kawai N, Ono K, Sukegawa E, Tsubuku S, Takahashi M. Assessment of acute adverse effects of glycine ingestion at a high dose in human volunteers. Seikatsu Eisei. 2006; 50:27-32.
- Woods SW, Walsh BC, Hawkins KA, Miller TJ, Saksa JR, D'Souza DC, Pearlson GD, Javitt DC, McGlashan TH, Krystal JH. Glycine treatment of the risk syndrome for psychosis: report of two pilot studies. Eur Neuropsychopharmacol. 2013 Aug;23(8):931-40. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC