No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Grass-Fed Colostrum Ingredients & Drug Interactions

by Heart & Soil

Capsule Category: Non-nutrient/non-botanical
No known interaction
The interaction bottom line No known interaction

Grass-Fed Colostrum is a dietary supplement by Heart & Soil with 1 active ingredient. Its ingredients are commonly taken for immune support, gut health and digestion, exercise recovery.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Grass-Fed Colostrum by Heart & Soil

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains a single active ingredient: bovine colostrum, which is the nutrient-rich first milk produced by cows after calving. It's known to contain immunoglobulins (antibodies) and other proteins that play a role in immune function and gut health.

The capsule itself is made from gelatin, an inactive ingredient that holds the colostrum.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: immune support and gut health.
  • We looked for evidence on: Exercise-induced respiratory infections, HIV/AIDS-related diarrhea, Influenza, Rotaviral diarrhea, Short bowel syndrome, Travelers' diarrhea — and 4 related terms.
  • The strongest evidence on file: Bovine Colostrum is rated "Possibly Effective" for HIV/AIDS-related diarrhea (Natural Medicines).
  • Also on file: Bovine Colostrum is rated "Possibly Effective" for Exercise-induced respiratory infections, Rotaviral diarrhea.
  • Also on file: Bovine Colostrum is rated "Possibly Ineffective" for Short bowel syndrome.

The evidence for bovine colostrum is mixed. It's rated possibly effective for HIV/AIDS-related diarrhea, rotaviral diarrhea, and exercise-induced respiratory infections.

For necrotizing enterocolitis — a serious intestinal condition in premature infants — the evidence suggests it may not be effective. The data we hold doesn't cover other uses you might have heard about.

The evidence, ingredient by ingredient Bovine Colostrum

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Bovine colostrum is generally well tolerated in most adults. A small number of trial participants reported mild bloating, nausea, diarrhea, and unsettled stomach — at about the same rate as those taking a whey-based control.

In people with HIV who were treated for infectious diarrhea, a few cases of elevated liver function tests and decreased blood cell counts (hematocrit) have been reported; one person with HIV-related cryptosporidiosis experienced nausea and vomiting. If you're pregnant, we don't have enough reliable safety data to know whether it's okay to use — talk to your doctor or pharmacist for personalized advice.

During breastfeeding, safety data is limited and caution is advised; check with your provider before taking it.

Side effects, ingredient by ingredient Bovine Colostrum

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented for bovine colostrum in our data with any medication types. That doesn't mean none could occur — if you're on prescription drugs, use the search tool on this page to check your exact medications.

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

Bovine colostrum may help with certain types of infectious diarrhea and exercise-related respiratory symptoms, though the evidence is modest. If you have a milk or dairy allergy, it's off limits.

Pregnant or nursing? Check with your doctor first.

Otherwise, run your medications through the checker to be thorough.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Grass-Fed Colostrum, straight from the product label.

Brand Heart & Soil
Barcode (UPC) 850018088091
Net contents 180 Capsule(s)
Market status On market
Date entered into DSLD Oct 24, 2024
DSLD ID 318817
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Grass-Fed Colostrum by Heart & Soil, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
6 Capsule(s)
Maximum serving Sizes:
6 Capsule(s)
Servings per container
30
UPC/BARCODE
850018088091
IngredientAmount% DV
Bovine Colostrum3000 mg--

Other ingredients: Gelatin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Reclaim your birthright to radical health. It breaks my heart to see how our families and our children struggle with fatigue, brain fog, mood issues, infertility, and autoimmunity. Is this the new normal that will become our future? Why have we forsaken the vitality that is our birthright and accepted this suffering as inescapable? I believe with all my soul that the solution is nose-to-tail nourishment. It starts with the soil and regenerative practices that heal the land, love, and nourish our animals so that we may be deeply nourished in turn. When we honor and consume animals nose-to-tail, we receive all the nutrients needed to thrive, in the most bioavailable forms. This is my passion, my purpose, my entire heart & soul. Let me show you a brighter future. Visit us online at www.heartandsoil.co to start your journey today. Paul Saladino, M.D.

30 day supply

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formula

3g colostrum per serving Grass-fed colostrum 500 mg ea

Formulation

Regenerative Small batch 100% grass-fed 100% grass-finished

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested use: 6 capsules daily or as directed by a healthcare professional

See for yourself

Grass-Fed Colostrum by Heart & Soil label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Grass-Fed Colostrum by Heart & Soil

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size6 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Bovine Colostrum

No known
interactions
3000 mg per serving Form: Bovine Milk, Immunoglobulin

Bovine colostrum is the nutrient-rich first milk from cows, packed with antibodies, growth factors, and protein. Early research suggests it may help w...

Bovine Colostrum monograph & interactions

Other (inactive) ingredients: Gelatin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Grass-Fed Colostrum by Heart & Soil Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Grass-Fed Colostrum. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Grass-Fed Colostrum, from the product label.

Heart & Soil

See all Heart & Soil products
Name
Heart & Soil, LLC.
City
Austin
State
TX
ZipCode
78746
Web Address
www.heartandsoil.co
Pharmacist Counseling Corner

Grass-Fed Colostrum by Heart & Soil: Common Questions

Does Grass-Fed Colostrum by Heart & Soil interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Grass-Fed Colostrum. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Grass-Fed Colostrum contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Who should avoid this product?
Anyone with a milk or dairy allergy should skip it, since bovine colostrum is a dairy product. If you're pregnant, we don't have enough safety data to know either way — talk to your doctor. During breastfeeding, safety data is limited, so check with your provider first.
What side effects might I notice?
A few people in clinical trials reported mild bloating, nausea, diarrhea, or an unsettled stomach — roughly the same rate as a control group. In HIV patients, elevated liver function tests and changes in blood cell counts have been reported in a small number of cases.
Does bovine colostrum actually work for diarrhea?
The evidence is modest. It's rated possibly effective for diarrhea related to HIV/AIDS and rotavirus infection, meaning some evidence supports it but results aren't definitive. For other causes of diarrhea, the data we hold doesn't speak to effectiveness.
What is bovine colostrum, exactly?
It's the first milk produced by cows after they give birth. It's rich in immunoglobulins — natural antibodies — and other proteins that support immune and gut function.
Does it interact with my medications?
No interactions are documented in our data. That doesn't guarantee none exist, so use the medication checker on this page with your exact drugs to be sure.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Grass-Fed Colostrum is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Grass-Fed Colostrum label
Go deeper

The Full Monographs Behind Grass-Fed Colostrum’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Grass-Fed Colostrum's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 8 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Bovine Colostrum 8 references
  1. Lewis CJ. Letter to reiterate certain public health and safety concerns to firms manufacturing or importing dietary supplements that contain specific bovine tissues. FDA. Available at: www.cfsan.fda.gov/~dms/dspltr05.html.
  2. Greenberg PD, Cello JP. Treatment of severe diarrhea caused by Cryptosporidium parvum with oral bovine immunoglobulin concentrate in patients with AIDS. J Acquir Immune Defic Syndr Hum Retrovirol 1996;13:348-54. PubMed
  3. Duff WR, Chilibeck PD, Rooke JJ, Kaviani M, Krentz JR, Haines DM. The effect of bovine colostrum supplementation in older adults during resistance training. Int J Sport Nutr Exerc Metab. 2014 Jun;24(3):276-85. PubMed
  4. Sanctuary MR, Kain JN, Chen SY, et al. Pilot study of probiotic/colostrum supplementation on gut function in children with autism and gastrointestinal symptoms. PLoS One. 2019;14(1):e0210064. PubMed
  5. Porcaro F, Caminiti L, Crisafulli G, Guglielmo F, Pajno GB. Anaphylaxis to cutaneous exposure to bovine colostrum based cream. Asian Pac J Allergy Immunol. 2019;37(1):9-11.
  6. Yan X, Pan X, Ding L, et al. Bovine colostrum to supplement the first feeding of very preterm infants: The PreColos randomized controlled trial. Clin Nutr 2023;42(8):1408-1417. PubMed
  7. Halasa M, Skonieczna-Zydecka K, Machalinski B, Bühner L, Baskiewicz-Halasa M. Six Weeks of Supplementation with Bovine Colostrum Effectively Reduces URTIs Symptoms Frequency and Gravity for Up to 20 Weeks in Pre-School Children. Nutrients 2023;15(16):3626 PubMed
  8. Simonsen MB, Kappel SS, Aunsholt L, Möller S, Sangild PT, Zachariassen G. Mineral supplementation for very preterm infants fed fortified human milk. J Pediatr Gastroenterol Nutr 2024;78(6):1389-1397. PubMed

See these in context on the Bovine Colostrum monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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