Interactions on record — worth a quick check against your medications. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Bone Marrow & Liver Ingredients & Drug Interactions

by Heart & Soil

Bone Marrow & Liver label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Minor
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Bone Marrow & Liver against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Minor

Bone Marrow & Liver is a dietary supplement by Heart & Soil with 2 active ingredients. Its ingredients are commonly taken for anemia and low iron, vitamin b12 support, general energy and fatigue.Based on those ingredients, 3 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are New Zealand grassfed Liver. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Bone Marrow & Liver by Heart & Soil

Ask about any prescription or over-the-counter medication and we check it for interactions with Bone Marrow & Liver by Heart & Soil — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Bone Marrow & Liver by Heart & Soil

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains two active ingredients: New Zealand grassfed liver extract and New Zealand grassfed bone marrow. The liver contributes vitamins, minerals, and other compounds traditionally valued in ancestral diets.

Bone marrow is included for similar nutritional support. The capsule itself is made with gelatin as an inactive ingredient.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Liver Extract product and its label doesn't state a use — see Liver Extract's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

We don't have effectiveness data on file for this product. For chronic fatigue syndrome (CFS), the liver extract is rated possibly ineffective — meaning the evidence doesn't back up its use for that condition.

For hepatitis C, there isn't enough reliable evidence to rate whether it works or doesn't. If you're considering this for a specific health goal, talk with your pharmacist or doctor about what evidence exists.

The evidence, ingredient by ingredient Liver Extract

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

No adverse reactions have been reported, but a thorough safety evaluation hasn't been done. There are two cautions to know about.

Liver products can deliver very high levels of vitamin A, which could harm a developing baby — avoid it in pregnancy unless your doctor says otherwise. There's also concern about potential contamination: liver extract comes from raw animal liver sourced from slaughterhouses, possibly from sick animals, and cow liver from countries where mad cow disease (BSE) has occurred could theoretically carry that risk, though no human cases from contaminated liver extract have been reported.

Until more is known, choose products from countries where BSE hasn't been documented.

Side effects, ingredient by ingredient Liver Extract

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Liver Extract.
  • The most serious interaction on file is rated Minor.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 3 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your exact medications before starting if you take warfarin (Coumadin) or any iron supplements or iron-containing medications — both carry documented Minor interactions with the liver extract in this product.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Only minor medication interactions are documented, and safety information is well characterized.

This is a whole-food-based supplement aimed at people interested in ancestral nutrition. If you take warfarin or iron supplements, check your exact medications with our tool before adding this product.

Pregnant people should avoid it unless their doctor approves. Talk with your pharmacist before starting, especially if you have any iron-related conditions or take medications regularly.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Bone Marrow & Liver, straight from the product label.

Brand Heart & Soil
Barcode (UPC) 850018088008
Net contents 180 Capsule(s)
Market status On market
Date entered into DSLD Oct 24, 2022
DSLD ID 276346
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Bone Marrow & Liver by Heart & Soil, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
6 Capsule(s)
Maximum serving Sizes:
6 Capsule(s)
Servings per container
30
UPC/BARCODE
850018088008
IngredientAmount% DV
New Zealand grassfed Liver1500 mg--
New Zealand grassfed Bone Marrow1500 mg--

Other ingredients: Gelatin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Reclaim your birthright to radical health. It breaks my heart to see how our families and our children struggle with fatigue, brain fog, mood issues, infertility, and autoimmunity. Is this the new normal that will become our future? Why have we forsaken the vitality that is our birthright and accepted this suffering as inescapable? I believe with all my soul that the solution is nose-to-tail nourishment. It starts with the soil and regenerative practices that heal the land, love, and nourish our animals so that we may be deeply nourished in turn. When we honor and consume animals nose-to-tail, we receive all of the nutrients needed to thrive, in the most bioavailable forms. This is my passion, my purpose, my entire heart & soul. Let me show you a brighter future. Visit us online at www.heartandsoil.co to start your journey today. Paul Saladino, M.D.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formula

3 g organs per serving

Bone Marrow & Liver 500 mg ea 180 capsules

Formulation

Regenerative Small batch 100% grass-fed 100% grass-finished

Suggested/Recommended/Usage/Directions

Suggested Use: 6 capsules daily or as directed by a healthcare professional

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Bone Marrow & Liver by Heart & Soil label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Bone Marrow & Liver label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Bone Marrow & Liver by Heart & Soil

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size6 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

New Zealand grassfed Liver

Interacts with
3 drugs
1500 mg per serving Form: Bovine

Liver extract is a dried or concentrated form of animal liver that is naturally rich in iron, vitamin B12, vitamin A, and other nutrients. It was once...

New Zealand grassfed Liver monograph & interactions

New Zealand grassfed Bone Marrow

1500 mg per serving Form: Bovine

Other (inactive) ingredients: Gelatin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Bone Marrow & Liver by Heart & Soil Drug Interactions

Want to check YOUR meds against Bone Marrow & Liver?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
3Drugs
3 Minor

Ingredients driving the most interactions

New Zealand grassfed Liver 3

Individual Drug Interactions

The ingredients in Bone Marrow & Liver interact with 3 drugs. Click any drug to see the details.

1 of the 2 ingredients in Bone Marrow & Liver interact with drugs. Each result below shows which ingredient is responsible. New Zealand grassfed Liver

Each ingredient & the kinds of drugs it affects

For each ingredient in Bone Marrow & Liver with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

New Zealand grassfed Liver2 drug types · 3 drugs

Iron

Liver extract can contain heme iron. Taking liver extract with iron-containing medications or supplements may increase total iron intake and could increase the risk of gastrointestinal adverse effects or excessive iron accumulation. The risk is greater with high doses, prolonged use, or in individuals with hemochromatosis or another iron-overload disorder. Review the iron content of the liver extract and the total elemental iron dose. Avoid unnecessary duplicate iron supplementation and consider monitoring ferritin and transferrin saturation when clinically appropriate.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Liver extract products may contain small and variable amounts of vitamin K. Theoretically, starting, stopping, or substantially changing the amount of liver extract used could reduce the anticoagulant effect of warfarin and lower the INR. However, this interaction has not been directly studied or reported in humans, and the vitamin K content of liver extract products is generally not standardized. Consider monitoring the INR after a meaningful change in liver extract use.

Likelihood Possible Evidence C
New Zealand grassfed Liver full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Bone Marrow & Liver, from the product label.

Heart & Soil

See all Heart & Soil products
Name
Heart & Soil, LLC.
City
Austin
State
TX
ZipCode
78746
Web Address
www.heartandsoil.co
Pharmacist Counseling Corner

Bone Marrow & Liver by Heart & Soil: Common Questions

Does Bone Marrow & Liver by Heart & Soil interact with any medications?
Yes. Based on its ingredients, Bone Marrow & Liver has a known interaction with 3 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Bone Marrow & Liver contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does liver extract really affect how warfarin works?
Liver extract can contain small amounts of vitamin K, which warfarin works against. In theory, big changes in how much you take could shift your blood-thinning level, but this hasn't actually been studied or reported in people. That's why it's Minor, not Major — but definitely worth checking with your pharmacist if you're on warfarin.
Can I take this if I already take iron supplements?
Both liver extract and your iron supplement contain iron, so taking them together could push your total iron intake higher than intended. The risk is higher if you take big doses, use it for a long time, or have a condition like hemochromatosis that makes iron buildup a concern. Talk to your pharmacist about spacing or dose.
Is this safe during pregnancy?
Liver products contain very high vitamin A, which can harm a developing baby. The safety data advises against it unless your doctor specifically recommends it. Definitely ask your doctor or pharmacist before taking this if you're pregnant.
Where does the liver come from, and is it tested?
The product uses New Zealand grassfed liver. The data we hold notes there's a concern about contamination from raw animal liver sourced from slaughterhouses, and about mad cow disease (BSE) in cow products from certain countries. No human cases from contaminated liver extract have been reported, but the label or manufacturer should clarify their sourcing and testing.
Does this actually work for fatigue or hepatitis?
The evidence on liver extract for chronic fatigue is rated possibly ineffective — meaning it doesn't back up that use. For hepatitis C, there isn't enough reliable evidence either way to say whether it works. This is a food-based supplement, not a treatment for disease.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Bone Marrow & Liver label
Go deeper

The Full Monographs Behind Bone Marrow & Liver’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Liver Extract

Interacts with 3 drugs

Liver extract is a dried or concentrated form of animal liver that is naturally rich in iron, vitamin B12, vitamin A, and other nutrients. It was once used to treat certain anemias before pu...

Read the full Liver Extract monograph →
Sources

Sources & How We Checked

Bone Marrow & Liver's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Liver Extract 4 references
  1. Lewis CJ. Letter to reiterate certain public health and safety concerns to firms manufacturing or importing dietary supplements that contain specific bovine tissues. FDA. Available at: www.cfsan.fda.gov/~dms/dspltr05.html.
  2. Kaslow JE, Rucker L, Onishi R. Liver extract-folic acid-cyanocobalamin vs placebo for chronic fatigue syndrome. Arch Intern Med 1989;149:2501-3. DOI
  3. Ebinuma, H., Saito, H., Tada, S., Masuda, T., Kamiya, T., Nishida, J., Yoshioka, M., and Ishii, H. Additive therapeutic effects of the liver extract preparation mixture adelavin-9 on interferon-beta treatment for chronic hepatitis C. Hepatogastroenterolog
  4. Saito, H., Ebinuma, H., Tada, S., Tsunematsu, S., Atsukawa, K., Masuda, T., Tsuchiya, M., and Ishii, H. Enhancing effect of the liver extract and flavin adenin dinucleotide mixture on anti-viral efficacy of interferon in patients with chronic hepatitis C. PubMed

See these in context on the Liver Extract monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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