Graviola 600 mg Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Graviola 600 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Graviola 600 mg is a dietary supplement by Swanson Premium Brand with 1 active ingredient. Its ingredients are commonly taken for cancer support (unproven), infections, inflammation.Based on those ingredients, 1 medication has a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Graviola. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Graviola 600 mg by Swanson Premium Brand
Ask about any prescription or over-the-counter medication and we check it for interactions with Graviola 600 mg by Swanson Premium Brand — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Graviola 600 mg by Swanson Premium Brand
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Graviola 600 mg by Swanson Premium Brand contains one active ingredient: graviola, a plant extract traditionally used in herbal medicine. The capsule also contains inactive ingredients—gelatin, rice powder, and silica—which serve as the capsule shell and flow agents.
Does it work?
Couldn't assess
The evidence we hold does not establish that graviola is effective for the conditions it's marketed for. The available data rate its use for human papillomavirus (HPV), headache, male infertility, and as an insect repellent all as having insufficient reliable evidence.
In plain terms, we don't have solid proof it works for any of these purposes.
How safe is it?
Well-documented data
Graviola's safety profile raises real concerns, especially with regular use. The most common side effects reported in studies are stomach pain and nausea.
More seriously, long-term graviola consumption has been linked to rare but potentially severe movement disorders and nerve damage (myeloneuropathy)—symptoms that can mimic Parkinson disease. A large observational study found that even low cumulative consumption of graviola fruit, juice, or herbal tea worsened motor and cognitive symptoms in people with Parkinson disease.
Graviola is rated possibly unsafe in pregnancy and should be avoided while breastfeeding due to insufficient safety data. Because human safety data are limited and lab studies raise concerns about possible nerve toxicity with long-term use, talk with your doctor or pharmacist before taking this supplement, especially if you are pregnant, breastfeeding, or have a personal or family history of Parkinson disease or movement disorders.
Meds to double-check
Moderate interaction found
If you take carbamazepine (Tegretol) or any other seizure medication, check with your doctor or pharmacist before starting graviola—it may lower your drug's blood levels and reduce its effectiveness. Even though carbamazepine is the only medication we have documented interaction data for, always confirm with your healthcare provider before combining any supplement with your medications.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Graviola's effectiveness for common uses is unproven, and regular use carries safety concerns—including stomach upset and rare but serious nerve and movement problems. If you take carbamazepine or other seizure medications, do not start graviola without checking with your doctor first.
Because of limited human safety data and potential long-term risks, discuss this supplement with your own doctor or pharmacist before taking it, especially if you're pregnant, breastfeeding, or at risk for movement disorders.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 31, 2018.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Graviola 600 mg, straight from the product label.
| Brand | Swanson Premium Brand |
|---|---|
| Barcode (UPC) | 087614113487 |
| Net contents | 60 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Aug 31, 2018 |
| DSLD ID | 176119 |
| Product type | Botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Graviola 600 mg by Swanson Premium Brand, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Graviola | 600 mg | -- |
Other ingredients: Gelatin, Rice powder, Silica
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
Bringing wellness to the world since 1969
To reorder, call toll free 1-800-437-4148 or visit our website at www.swansonvitamins.com
FDA Statement of Identity
Herbal Supplement
Seals/Symbols
Guaranteed purity & potency
Precautions
Do not use if seal is broken.
Keep out of reach of children.
Warning: Do not take this product if you are pregnant or nursing. Consult your healthcare provider before use if you are taking blood pressure medication or products that increase ATP levels (CoQ10).
If taking this product for longer than 30 days, supplementing with probiotics and digestive enzymes is recommended. Long-term use and/or excessive use can lead to changes in neurological function. Discontinue use immediately if you experience any changes in neurological function.
Storage
Store in a cool, dry place.
Suggested/Recommended/Usage/Directions
Suggested Use: As a dietary supplement, take one capsule per day with water.
General
SW1348 Rev 0 05 01 17
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Graviola 600 mg by Swanson Premium Brand label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Graviola 600 mg by Swanson Premium Brand
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.
Graviola
Interacts with1 drug
Graviola (soursop) is a tropical fruit tree whose leaves, fruit, and bark are used in traditional medicine, especially in parts of South America, Afri...
Graviola monograph & interactionsOther (inactive) ingredients: Gelatin, Rice powder, Silica. These complete the product’s ingredient list but are not active constituents.
Graviola 600 mg by Swanson Premium Brand Drug Interactions
HelloPharmacist Interaction Report
Graviola 600 mg by Swanson Premium Brand interacts with one medication: carbamazepine (Tegretol), a seizure drug.
The interaction is Moderate in severity. When taken together, graviola may lower the levels of carbamazepine in your blood, potentially making the medication less effective at controlling seizures.
A rat study showed that graviola extract reduced carbamazepine concentrations by 35–46% compared to the drug alone.
Read the full breakdown — every affected drug type, severity by severity
Although carbamazepine is the only medication with documented interaction data for graviola, if you take any seizure medications, blood pressure drugs, or other prescription medications, check with your doctor or pharmacist before starting this supplement. Altogether, these interactions span 1 individual medication.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Graviola 600 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Graviola 600 mg interact with 1 drug. Click any drug to see the details.
1 of the 1 ingredient in Graviola 600 mg interact with drugs. Each result below shows which ingredient is responsible. Graviola
CarbamazepineCarbatrol, Carnexiv, Equetro, Tegretol, Tegretol XR
How Carbamazepine interacts with Graviola 600 mg — through 1 ingredient. Tap an ingredient for the detail:
GraviolaCarbamazepine (tegretol) Moderate
Interaction Summary
Theoretically, graviola might decrease concentrations of carbamazepine when used concomitantly.
Read the full Graviola + Carbamazepine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Graviola 600 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Graviola
Carbamazepine (Tegretol)
Theoretically, graviola might decrease concentrations of carbamazepine when used concomitantly.
A study in rats shows that graviola extract reduces the area under the curve of carbamazepine by 46% and maximum concentration by 35% when compared with carbamazepine alone.
Brand information
Manufacturer and brand details for Graviola 600 mg, from the product label.
Swanson Premium Brand
See all Swanson Premium Brand products- Name
- Swanson Health Products
- City
- Fargo
- State
- ND
- ZipCode
- 58104
- Phone Number
- 1-800-437-4148
- Web Address
- www.swansonvitamins.com
Graviola 600 mg by Swanson Premium Brand: Common Questions
Does Graviola 600 mg by Swanson Premium Brand interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take Graviola if I'm pregnant or breastfeeding?
What are the most common side effects?
Does graviola actually work for HPV, headaches, or male infertility?
Why is regular consumption flagged as unsafe?
I take a seizure medication—can I take Graviola?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Graviola 600 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Graviola 600 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Graviola 600 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 4 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Graviola 4 references
- Caparros-Lefebvre D, Elbaz A. Possible relation of atypical parkinsonism in the French West Indies with consumption of tropical plants: a case-control study. Caribbean Parkinsonism Study Group. Lancet 1999;354:281-6. PubMed
- Gavamukulya Y, Wamunyokoli F, El-Shemy HA. Annona muricata: Is the natural therapy to most disease conditions including cancer growing in our backyard? A systematic review of its research history and future prospects. Asian Pac J Trop Med. 2017;10(9):835- PubMed
- Abu Soukhon AA, Abu-Qatouseh L, Mansoor K, et al. Cytotoxicity Activity of Graviola Fruit Extract with Carbamazepine and Valproic Acid Show Antagonistic and Indifferent Effects. Asian Pac J Cancer Prev 2023;24(6):1869-1875. PubMed
- Cleret de Langavant L, Roze E, Petit A, et al. Annonaceae Consumption Worsens Disease Severity and Cognitive Deficits in Degenerative Parkinsonism. Mov Disord 2022;37(12):2355-2366. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC