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Dietary supplement

Full Spectrum Gentian Root 400 mg Ingredients & Drug Interactions

by Swanson Premium Brand

Full Spectrum Gentian Root 400 mg label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Full Spectrum Gentian Root 400 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Full Spectrum Gentian Root 400 mg is a dietary supplement by Swanson Premium Brand with 1 active ingredient. Its ingredients are commonly taken for loss of appetite, indigestion and bloating, digestive bitter tonic.Based on those ingredients, 172 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Gentian. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Full Spectrum Gentian Root 400 mg by Swanson Premium Brand

Ask about any prescription or over-the-counter medication and we check it for interactions with Full Spectrum Gentian Root 400 mg by Swanson Premium Brand — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Full Spectrum Gentian Root 400 mg by Swanson Premium Brand

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 30, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: gentian root at 400 mg per capsule. Gentian is a plant root used traditionally for digestive support and other purposes.

The capsule itself is made from gelatin and rice flour.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Gentian's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: digestive support and appetite stimulation.
  • We looked for evidence on: Diarrhea, Flatulence, Gastritis, Gastroesophageal reflux disease (GERD), indigestion, bloating — and 1 related terms.
  • The closest evidence on file: Gentian is rated "Insufficient Reliable Evidence To Rate" for Diarrhea (Natural Medicines).
  • Also on file: Gentian is rated "Insufficient Reliable Evidence To Rate" for Gastroesophageal reflux disease (GERD), Flatulence, Gastritis.

The evidence we hold on gentian for wound healing, obesity, rhinosinusitis, and gastritis is insufficient — meaning we don't have enough reliable data to say whether it works for these uses. If you're considering this product for one of those reasons, talk with your doctor or pharmacist about whether the evidence supports it.

The evidence, ingredient by ingredient Gentian

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Gentian is generally well tolerated in small amounts by healthy adults, but it can upset your stomach. It hasn't been studied at high doses, so we don't know how safe those are.

In one trial, patients taking gentian along with turmeric and ginger reported nausea, vomiting, diarrhea, and bloating; a small number stopped the regimen because of these effects. The safety data advises against gentian during pregnancy and while breastfeeding because there isn't enough reliable information to know it's safe at those times.

If you're pregnant or nursing, talk with your doctor or pharmacist before taking it.

Side effects, ingredient by ingredient Gentian

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Gentian.
  • The most serious interaction on file is rated Moderate.
  • For scale: 172 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take blood pressure-lowering medications (antihypertensives), check with your doctor or pharmacist before starting this product. Gentian may add to their blood-pressure-lowering effect and lower your pressure too much.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Gentian root is traditionally used for digestive support, but the evidence for most of its claimed uses is insufficient. The main thing to watch for is interaction with blood pressure medications — if you take any, clear this with your doctor or pharmacist first.

It may upset your stomach, especially at higher doses or combined with other herbs.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 25, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Full Spectrum Gentian Root 400 mg, straight from the product label.

Brand Swanson Premium Brand
Barcode (UPC) 087614112947
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Jun 25, 2018
DSLD ID 178292
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Full Spectrum Gentian Root 400 mg by Swanson Premium Brand, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
UPC/BARCODE
087614112947
IngredientAmount% DV
Gentian400 mg--

Other ingredients: Gelatin, Rice Flour, May contain one or both of the following

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Bringing wellness to the world since 1969

To reorder, call toll free 1-800-437-4148 or visit our website at www.swansonvitamins.com

FDA Statement of Identity

Herbal Supplement

Seals/Symbols

Guaranteed purity & potency

Precautions

Do not use if seal is broken.

Keep out of reach of children.

Warning: Do not take this product if you are pregnant, nursing or if you have or have had ulcers.

Storage

Store in a cool, dry place.

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, take one capsule per day with water.

General

SW1294

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Full Spectrum Gentian Root 400 mg by Swanson Premium Brand label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Full Spectrum Gentian Root 400 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Full Spectrum Gentian Root 400 mg by Swanson Premium Brand

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.

Gentian

Interacts with
172 drugs
400 mg per serving

Gentian is a very bitter root traditionally used to stimulate appetite and ease mild digestive complaints, often as part of "bitters" before meals. Th...

Gentian monograph & interactions

Other (inactive) ingredients: Gelatin, Rice Flour, May contain one or both of the following. These complete the product’s ingredient list but are not active constituents.

Interaction report

Full Spectrum Gentian Root 400 mg by Swanson Premium Brand Drug Interactions

Want to check YOUR meds against Full Spectrum Gentian Root 400 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
172Drugs
172 Moderate

Ingredients driving the most interactions

Gentian 172

Individual Drug Interactions

The ingredients in Full Spectrum Gentian Root 400 mg interact with 172 drugs. Click any drug to see the details.

1 of the 1 ingredient in Full Spectrum Gentian Root 400 mg interact with drugs. Each result below shows which ingredient is responsible. Gentian

Each ingredient & the kinds of drugs it affects

For each ingredient in Full Spectrum Gentian Root 400 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Gentian1 drug type · 172 drugs

Antihypertensive Drugs

Theoretically, taking gentian with antihypertensive drugs might increase the risk of hypotension.
In vitro research shows that gentian can cause vasodilation and lower blood pressure.

Likelihood Possible Evidence D
Gentian full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Full Spectrum Gentian Root 400 mg, from the product label.

Swanson Premium Brand

See all Swanson Premium Brand products
Name
Swanson Health Products
Street Address
PO BOX 2803
City
Fargo
State
ND
ZipCode
58108
Phone Number
1-800-437-4148
Web Address
www.swansonvitamins.com
Pharmacist Counseling Corner

Full Spectrum Gentian Root 400 mg by Swanson Premium Brand: Common Questions

Does Full Spectrum Gentian Root 400 mg by Swanson Premium Brand interact with any medications?
Yes. Based on its ingredients, Full Spectrum Gentian Root 400 mg has a known interaction with 172 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Full Spectrum Gentian Root 400 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
No. The safety data advises against gentian during pregnancy and while breastfeeding because there isn't enough reliable information to know it's safe at those times. Talk with your doctor or pharmacist about whether it's right for you.
What does gentian root do?
Gentian is traditionally used for digestive support and other purposes, but we don't have enough reliable evidence to say it works for wound healing, obesity, rhinosinusitis, or gastritis.
What side effects might I experience?
Gentian can upset your stomach. In one trial combining it with turmeric and ginger, a small number of patients reported nausea, vomiting, diarrhea, and bloating, and some had to stop taking it because of these effects.
Does this contain any fillers?
The capsule is made from gelatin and rice flour, which are inactive ingredients. The product may also contain one or both of two other unspecified ingredients.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Full Spectrum Gentian Root 400 mg is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Full Spectrum Gentian Root 400 mg label
Go deeper

The Full Monographs Behind Full Spectrum Gentian Root 400 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Gentian

Interacts with 172 drugs

Gentian is a very bitter root traditionally used to stimulate appetite and ease mild digestive complaints, often as part of "bitters" before meals. The evidence is mostly traditional and pre...

Read the full Gentian monograph →
Sources

Sources & How We Checked

Full Spectrum Gentian Root 400 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Gentian 5 references
  1. Neubauer N, Marz RW. Placebo-controlled, randomized, double-blind, clincal trial with Sinupret sugar coated tablets on the basis of a therapy with antibiotics and decongestant nasal drops in acute sinusitis. Phytomedicine 1994;1:177-81.
  2. Marz RW, Ismail C, Popp MA. Action profile and efficacy of a herbal combination preparation for the treatment of sinusitis. Wien Med Wochenschr 1999;149:202-8.
  3. Uncini Manganelli RE, Chericoni S, Baragatti B. Ethnopharmacobotany in Tuscany: plants used as antihypertensives. Fitoterapia 2000;71:S95-100. PubMed
  4. Baragatti B, Calderone V, Testai L, et al. Vasodilator activity of crude methanolic extract of Gentiana kokiana Perr. et Song. (Gentianaceae). J Ethnopharmacol 2002;79:369-72. PubMed
  5. Sanatani M, Younus J, Stitt L, et al. Tolerability of the combination of ginger (Zingiber officinalis), gentian (Gentiana lutea) and turmeric (Curcuma longa) in patients with cancer-associated anorexia. J Complement Integr Med. 2015;12(1):57-60.

See these in context on the Gentian monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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