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Dietary supplement

Graviola Caps Ingredients & Drug Interactions

by Amazon Thunder

Graviola Caps label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Graviola Caps against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Graviola Caps is a dietary supplement by Amazon Thunder with 1 active ingredient. Its ingredients are commonly taken for cancer support (unproven), infections, inflammation.Based on those ingredients, 1 medication has a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Graviola. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Graviola Caps by Amazon Thunder

Ask about any prescription or over-the-counter medication and we check it for interactions with Graviola Caps by Amazon Thunder — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Graviola Caps by Amazon Thunder

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 6, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Graviola Caps contains one active ingredient: graviola, a tropical plant extract. The capsule itself is made from vegetable material.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Graviola's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: immune health and healthy cell division.
  • We looked for evidence on: Diabetes, infection, inflammation, digestive health.
  • The closest evidence on file: Graviola is rated "Insufficient Reliable Evidence To Rate" for Diabetes (Natural Medicines).

The evidence for graviola isn't established. Our data show insufficient reliable evidence to rate it for HPV infection, headache, insect repellent use, or male infertility.

That doesn't mean it doesn't work—it means well-designed human studies haven't confirmed it yet.

The evidence, ingredient by ingredient Graviola

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Graviola raises some safety concerns. Regular use may cause nausea and upper abdominal pain; in rare cases, it has been linked to movement disorders and nerve damage (myeloneuropathy) that resemble Parkinson disease symptoms.

One study found that even low cumulative intake of graviola fruit, juice, or herbal tea may worsen motor and cognitive symptoms in people with Parkinson disease. During pregnancy, there isn't enough safety data, so it's best avoided.

The same goes for breastfeeding—reliable information doesn't exist, so steer clear. Because human safety data are limited overall and lab studies raise concerns about possible long-term nerve toxicity, use caution with this product.

Side effects, ingredient by ingredient Graviola

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Graviola.
  • The most serious interaction on file is rated Moderate.
  • For scale: 1 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take carbamazepine (Tegretol) for seizures, check with your doctor or pharmacist before using this product—graviola may reduce how well the medication works.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Graviola Caps is not well studied in humans, and safety data are limited. If you take carbamazepine (a seizure medication), do not use this product without checking with your doctor or pharmacist first.

If you're pregnant or breastfeeding, the safety data advise against it. Talk it over with your own doctor or pharmacist before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated May 24, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Graviola Caps, straight from the product label.

Brand Amazon Thunder
Barcode (UPC) 613103030388
Net contents 180 Vegetable Capsule(s); 90 g
Market status On market
Date entered into DSLD May 24, 2013
DSLD ID 21776
Product type Botanical
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Kosher, Organic
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Graviola Caps by Amazon Thunder, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
6 Capsule(s)
Maximum serving Sizes:
6 Capsule(s)
Servings per container
30
UPC/BARCODE
613103030388
IngredientAmount% DV
Graviola3000 mg--

Other ingredients: Vegetable Capsule

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

Do Not Take If You Have Low Blood Pressure Or Are Pregnant Or Lactating. Avoid combining with ATP-enhancers like CoQ10.

Keep out of reach of children.

Seals/Symbols

U

{recycle}

QUALITY ASSURANCE INTERNATIONAL CERTIFIED ORGANIC

100% PURE

General Statements

John-316.net

-Promotes Immune System Health -Promotes Healthy Cell Division and Aids In The Prevention Of Abnormal Cell Growth -Promotes The Elimination Of Unhealthy Bacteria, Fungus and Parasites -Promotes Digestion Stimulation -High in Vitamin C, B1 & B2 -Detoxifying Antioxidant Support

The Worlds Finest Amazon Rain Forest Graviola Western Science has identified less than 3% of the medicinal plants that grow in the Amazon Rainforest. Yet drugs derived from just these plants account for 25% of the Western medicine's pharmacopoeia, including some of the most potent medications known. Imagine what health miracles await us in the remaining 97%! Graviola, also known as soursop, comes from within the deep Amazon jungle regions of Brazil. Its various parts, including the leaves, stem, roots, fruit, seeds, and bark, have been used for centuries by Amazon natives to treat various ailments. Most of the benefits are safely derived from the leaves, stem and the fruit in proper balance. Amazon Thunder is the first and only company to make pure Graviola capsules using Organic and Kosher certified freeze dried Graviola leaves, fruit and stem of the highest quality balanced in proper proportion. Our Graviola freeze dried powder capsules are made with organic freeze dried graviola leaves and fruit. Our Graviola is kosher, fair trade compliant and sustainably harvested. Visit us on the web at www.amazonthunder.com for more information and to see all of our pure quality Amazon Rainforest wellness dietary supplements.

Made In The USA

FDA Disclaimer Statement

THIS STATEMENT HAS NOT BEEN EVALUATED BY THE U.S. FOOD AND DRUG ADMINISTRATION. THIS PRODUCT IS NOT INTENDED TO DIAGNOSE, TREAT, CARE FOR OR PREVENT ANY DISEASES.

Formulation

Certified Organic by: Quality Assurance International

No fillers, binders, flow agents or other additives. Contains no seeds, bark or root. (Annona muricata).

Formula

Ingredients: Organic & Kosher Freeze Dried Pure Amazon Thunder(R) Graviola Leaves, Stem and Fruit Body. In Proper Balance.

Made With Organic Freeze Dried Graviola

Suggested/Recommended/Usage/Directions

Suggested Use: Take up to 6 capsules daily with food or water. Take daily until empty. If used longer than 30 days supplement with probiotics.

Storage

Storage Instructions: Store unopened container in a cool dry place. Refrigerate after opening for optimum keeping.

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Graviola Caps by Amazon Thunder label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Graviola Caps label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Graviola Caps by Amazon Thunder

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size6 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Graviola

Interacts with
1 drug
3000 mg per serving

Graviola (soursop) is a tropical fruit tree whose leaves, fruit, and bark are used in traditional medicine, especially in parts of South America, Afri...

Graviola monograph & interactions

Other (inactive) ingredients: Vegetable Capsule. These complete the product’s ingredient list but are not active constituents.

Interaction report

Graviola Caps by Amazon Thunder Drug Interactions

Want to check YOUR meds against Graviola Caps?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1Drugs
1 Moderate

Ingredients driving the most interactions

Graviola 1

Individual Drug Interactions

The ingredients in Graviola Caps interact with 1 drug. Click any drug to see the details.

1 of the 1 ingredient in Graviola Caps interact with drugs. Each result below shows which ingredient is responsible. Graviola

Each ingredient & the kinds of drugs it affects

For each ingredient in Graviola Caps with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Graviola1 drug type · 1 drug

Carbamazepine (Tegretol)

Theoretically, graviola might decrease concentrations of carbamazepine when used concomitantly.
A study in rats shows that graviola extract reduces the area under the curve of carbamazepine by 46% and maximum concentration by 35% when compared with carbamazepine alone.

Likelihood Possible Evidence D
Graviola full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Graviola Caps, from the product label.

Amazon Thunder

See all Amazon Thunder products
Name
Amazon Thunder, Inc.
City
Carson City
State
NV
ZipCode
89701
Phone Number
1-800-696-0354
Web Address
www.amazonthunder.com
Pharmacist Counseling Corner

Graviola Caps by Amazon Thunder: Common Questions

Does Graviola Caps by Amazon Thunder interact with any medications?
Yes. Based on its ingredients, Graviola Caps has a known interaction with 1 medication. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Graviola Caps contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is graviola, and what is it supposed to do?
Graviola is an extract from a tropical plant. It's been studied for HPV infection, headache, insect repellent use, and male infertility, but we don't have enough reliable human evidence to confirm it works for any of these.
Can I take this while pregnant?
No. There isn't enough safety data during pregnancy, so the safety rating advises against it. Talk with your doctor or pharmacist about whether this product is right for you.
Can I take this while breastfeeding?
No. Reliable safety information doesn't exist for breastfeeding, so it's best avoided. Check with your doctor or pharmacist for personalized advice.
What side effects might I experience?
The most common side effects reported are nausea and burning pain in the upper abdomen. Rarely, long-term use has been linked to movement disorders and nerve damage. People with Parkinson disease appear especially at risk of worsened symptoms.
Is this safe to use long-term?
Regular consumption of graviola may be unsafe. Lab studies raise concerns about possible nerve toxicity with long-term use, and human safety data are limited, so caution is advised.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Graviola Caps is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Graviola Caps label
Go deeper

The Full Monographs Behind Graviola Caps’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Graviola

Interacts with 1 drug

Graviola (soursop) is a tropical fruit tree whose leaves, fruit, and bark are used in traditional medicine, especially in parts of South America, Africa, and Asia. Despite popular online cla...

Read the full Graviola monograph →
Sources

Sources & How We Checked

Graviola Caps's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Graviola 4 references
  1. Caparros-Lefebvre D, Elbaz A. Possible relation of atypical parkinsonism in the French West Indies with consumption of tropical plants: a case-control study. Caribbean Parkinsonism Study Group. Lancet 1999;354:281-6. PubMed
  2. Gavamukulya Y, Wamunyokoli F, El-Shemy HA. Annona muricata: Is the natural therapy to most disease conditions including cancer growing in our backyard? A systematic review of its research history and future prospects. Asian Pac J Trop Med. 2017;10(9):835- PubMed
  3. Abu Soukhon AA, Abu-Qatouseh L, Mansoor K, et al. Cytotoxicity Activity of Graviola Fruit Extract with Carbamazepine and Valproic Acid Show Antagonistic and Indifferent Effects. Asian Pac J Cancer Prev 2023;24(6):1869-1875. PubMed
  4. Cleret de Langavant L, Roze E, Petit A, et al. Annonaceae Consumption Worsens Disease Severity and Cognitive Deficits in Degenerative Parkinsonism. Mov Disord 2022;37(12):2355-2366. PubMed

See these in context on the Graviola monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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