Graviola Fruit 4:1 Extract Powder Ingredients & Drug Interactions
by TerraVita Premium Collection
What is this page for?
First and foremost: checking Graviola Fruit 4:1 Extract Powder against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Graviola Fruit 4:1 Extract Powder is a dietary supplement by TerraVita Premium Collection with 1 active ingredient. Its ingredients are commonly taken for cancer support (unproven), infections, inflammation.Based on those ingredients, 1 medication has a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Graviola Fruit Extract, Powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Graviola Fruit 4:1 Extract Powder by TerraVita Premium Collection
Ask about any prescription or over-the-counter medication and we check it for interactions with Graviola Fruit 4:1 Extract Powder by TerraVita Premium Collection — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Graviola Fruit 4:1 Extract Powder by TerraVita Premium Collection
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: graviola fruit extract in a concentrated 4:1 powder form, which means four parts of the original fruit have been reduced to one part of extract. There are no inactive ingredients listed.
Does it work?
Couldn't assess
The evidence we hold doesn't establish that graviola is effective for any of the conditions it's commonly used for—human papillomavirus (HPV), headache, use as an insect repellent, or male infertility. The data on file rates all of these as having insufficient reliable evidence.
That doesn't mean it doesn't work; it means robust human studies backing these uses aren't available in the information we have.
How safe is it?
Well-documented data
Regular consumption of graviola may be unsafe. The most common side effects reported are stomach pain (epigastrium pain) and nausea, which some people experienced in clinical trials at doses of 300 mg daily.
More serious but rare side effects include movement disorders and nerve damage (myeloneuropathy) that resemble Parkinson disease symptoms. One large observational study found that even small amounts of graviola consumed over time were linked to worsening movement and thinking problems in people with Parkinson disease.
Because human safety data are limited and lab studies raise concerns about possible nerve toxicity with long-term use, the safety data advises against use during pregnancy and while breastfeeding.
Meds to double-check
Moderate interaction found
If you take carbamazepine (Tegretol) or any other anti-seizure medication, check with your doctor or pharmacist before using this product. Graviola may lower carbamazepine levels and reduce its effectiveness at controlling seizures.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Graviola Fruit 4:1 Extract Powder is most concerning if you take carbamazepine for seizures—it may reduce that drug's effectiveness. Beyond that interaction, regular use carries the risk of stomach upset and rare but serious nerve-related side effects, and the evidence doesn't yet support its effectiveness for common conditions.
If you're pregnant, breastfeeding, have Parkinson disease, or take any medication, talk with your doctor or pharmacist before starting it.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 18, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Graviola Fruit 4:1 Extract Powder, straight from the product label.
| Brand | TerraVita Premium Collection |
|---|---|
| Barcode (UPC) | 064435203597 |
| Net contents | 4 Ounce(s) |
| Market status | On market |
| Date entered into DSLD | Jul 18, 2023 |
| DSLD ID | 289722 |
| Product type | Botanical |
| Supplement form | Powder |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Graviola Fruit 4:1 Extract Powder by TerraVita Premium Collection, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Graviola Fruit Extract, Powder | 1000 mg | -- |
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity
A Dietary Supplement
Brand IP Statement(s)
Copyright 2017 TerraVita - Distributed by ZooScape LLC, All Rights Reserved.
Suggested/Recommended/Usage/Directions
Directions Stir 1/4 of a teaspoon into a glass of water and consume 3 times daily, with meals.
General Statements
TerraVita is an exclusive line of premium natural products that use the finest, purest and most potent ingredients in the world. TerraVita's hallmarks are the highest possible standards of purity, potency, stability and freshness. All products are prepared with the greatest quality control, from raw materials through the entire manufacturing process, right up to the moment your product is sealed for freshness and shipped to you.
Please recycle!
FDA Disclaimer Statement
Statements not evaluated by FDA. Product not intended to diagnose, treat, cure, or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Graviola Fruit 4:1 Extract Powder by TerraVita Premium Collection label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Graviola Fruit 4:1 Extract Powder by TerraVita Premium Collection
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size0.25 Teaspoon(s) Dosage formPowder Servings per container28 Amounts shown are per serving.
Graviola Fruit Extract, Powder
Interacts with1 drug
Graviola (soursop) is a tropical fruit tree whose leaves, fruit, and bark are used in traditional medicine, especially in parts of South America, Afri...
Graviola Fruit Extract, Powder monograph & interactionsGraviola Fruit 4:1 Extract Powder by TerraVita Premium Collection Drug Interactions
HelloPharmacist Interaction Report
Graviola Fruit 4:1 Extract Powder by TerraVita Premium Collection interacts with one medication: carbamazepine (Tegretol), an anti-seizure drug.
The concern is Moderate in severity. Graviola appears to speed up how your body clears carbamazepine, which could lower the drug's concentration in your blood by up to 46% and reduce its peak level by 35%, based on animal studies.
This drop might make the medication less effective at controlling seizures.
Read the full breakdown — every affected drug type, severity by severity
If you take carbamazepine, you'll want to check with your doctor or pharmacist before starting this product. They may need to adjust your dose or monitor your seizure control more closely.
Use the medication checker on this page to confirm you're covered, or bring your full medication list to your pharmacist.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Graviola Fruit 4:1 Extract Powder?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Graviola Fruit 4:1 Extract Powder interact with 1 drug. Click any drug to see the details.
1 of the 1 ingredient in Graviola Fruit 4:1 Extract Powder interact with drugs. Each result below shows which ingredient is responsible. Graviola Fruit Extract, Powder
CarbamazepineCarbatrol, Carnexiv, Equetro, Tegretol, Tegretol XR
How Carbamazepine interacts with Graviola Fruit 4:1 Extract Powder — through 1 ingredient. Tap an ingredient for the detail:
Graviola Fruit Extract, PowderCarbamazepine (tegretol) Moderate
Interaction Summary
Theoretically, graviola might decrease concentrations of carbamazepine when used concomitantly.
Read the full Graviola Fruit Extract, Powder + Carbamazepine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Graviola Fruit 4:1 Extract Powder with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Graviola Fruit Extract, Powder
Carbamazepine (Tegretol)
Theoretically, graviola might decrease concentrations of carbamazepine when used concomitantly.
A study in rats shows that graviola extract reduces the area under the curve of carbamazepine by 46% and maximum concentration by 35% when compared with carbamazepine alone.
Brand information
Manufacturer and brand details for Graviola Fruit 4:1 Extract Powder, from the product label.
TerraVita Premium Collection
See all TerraVita Premium Collection products- Name
- TerraVita Fine Whole Herbs
- City
- Brampton
- State
- Ontario
Graviola Fruit 4:1 Extract Powder by TerraVita Premium Collection: Common Questions
Does Graviola Fruit 4:1 Extract Powder by TerraVita Premium Collection interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this while I'm pregnant or breastfeeding?
What are the side effects?
Does this actually work for what it's marketed for?
Should I avoid this if I have Parkinson disease?
Is this extract more or less concentrated than other graviola products?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Graviola Fruit 4:1 Extract Powder is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Graviola Fruit 4:1 Extract Powder’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Graviola Fruit 4:1 Extract Powder's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 4 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Graviola 4 references
- Caparros-Lefebvre D, Elbaz A. Possible relation of atypical parkinsonism in the French West Indies with consumption of tropical plants: a case-control study. Caribbean Parkinsonism Study Group. Lancet 1999;354:281-6. PubMed
- Gavamukulya Y, Wamunyokoli F, El-Shemy HA. Annona muricata: Is the natural therapy to most disease conditions including cancer growing in our backyard? A systematic review of its research history and future prospects. Asian Pac J Trop Med. 2017;10(9):835- PubMed
- Abu Soukhon AA, Abu-Qatouseh L, Mansoor K, et al. Cytotoxicity Activity of Graviola Fruit Extract with Carbamazepine and Valproic Acid Show Antagonistic and Indifferent Effects. Asian Pac J Cancer Prev 2023;24(6):1869-1875. PubMed
- Cleret de Langavant L, Roze E, Petit A, et al. Annonaceae Consumption Worsens Disease Severity and Cognitive Deficits in Degenerative Parkinsonism. Mov Disord 2022;37(12):2355-2366. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC