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Dietary supplement

He Ye Ingredients & Drug Interactions

by Herbal Terra

He Ye label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking He Ye against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

He Ye is a dietary supplement by Herbal Terra with 1 active ingredient. Its ingredients are commonly taken for digestive upset and diarrhea, anxiety and relaxation, sleep support.Based on those ingredients, 212 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are wildcrafted He Ye dried leaf liquid extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against He Ye by Herbal Terra

Ask about any prescription or over-the-counter medication and we check it for interactions with He Ye by Herbal Terra — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of He Ye by Herbal Terra

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 6, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

He Ye contains one active ingredient: a wildcrafted lotus leaf liquid extract. The extract is prepared using a menstruum, which is the liquid solvent used to draw out and preserve the plant's active compounds.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Lotus product and its label doesn't state a use — see Lotus's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for He Ye isn't established. Our data shows insufficient reliable evidence to rate this product for nausea and vomiting, sore throat (pharyngitis), insomnia, obesity, heavy menstrual bleeding (menorrhagia), or bleeding.

That doesn't mean it doesn't work — it means studies haven't been done yet or the ones available don't meet our standard for a solid rating.

The evidence, ingredient by ingredient Lotus

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lotus is common in food, but the safety of medicinal supplements hasn't been well studied in humans. The safety data for concentrated supplements like this one is too thin, so we advise against it.

Allergic reactions are possible — lotus root has caused hives and contact dermatitis in case reports, including a young child who developed hives after eating lotus root. There isn't enough safety data to know whether it's okay to use while breastfeeding, so it's best to avoid it during that time.

Side effects, ingredient by ingredient Lotus

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Lotus.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 212 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your doctor or pharmacist before using He Ye if you take any anticoagulants or antiplatelet drugs (blood thinners like warfarin or aspirin), diabetes medications, or barbiturate sedatives like pentobarbital. These are the main medication types documented to interact with lotus.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

He Ye may appeal to someone interested in traditional lotus remedies, but the evidence for its effectiveness isn't established, and it does interact with blood thinners, diabetes drugs, and possibly sedatives. If you're on any prescription medications — especially blood thinners or diabetes drugs — talk it over with your doctor or pharmacist before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about He Ye, straight from the product label.

Brand Herbal Terra
Barcode (UPC) 7429524213209
Net contents 4 Fluid Ounce(s); 120 mL
Market status On market
Date entered into DSLD Sep 25, 2020
DSLD ID 234870
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for He Ye by Herbal Terra, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 mL
Maximum serving Sizes:
1 mL
Servings per container
120
UPC/BARCODE
7429524213209
IngredientAmount% DV
wildcrafted He Ye dried leaf liquid extract970 mg--

Other ingredients: Menstruum

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Direction Shake well before use. Adults take up to 30 drops (1 mL, one full squeeze of the dropper bulb) in 3-4 fl. oz of juice or water up to 4 times a day. We recommend to seek expert medical advice before taking this or any other herbal supplements.

FDA Disclaimer Statement

Notice This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure, or prevent any disease.

Formulation

Manufactured in the USA in an FDA registered facility

Alcohol free

Dried herb/menstruum ratio: 1:3 Expertly extracted Laboratory tested 330 mg/1 mL Premium product Alcohol-free liquid herbal extract

Non GMO

No artificial ingredients, GMO, gluten, color additives, fillers, preservatives or binders. Natural Gluten Free

Precautions

Caution May have contraindications.

Do not use if you are allergic to any ingredients.

Consult a physician before using during pregnancy, if nursing, or if you are on any medications.

Keep out of the reach of children.

Storage

Store in a cool, dry, dark place.

Formula

Nelumbo nucifera

FDA Statement of Identity

Herbal Supplement

Seals/Symbols

Made in USA Made in an FDA registered facility Natural Gluten Free

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

He Ye by Herbal Terra label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

He Ye label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in He Ye by Herbal Terra

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 mL Dosage formLiquid Servings per container120 Amounts shown are per serving.

Wildcrafted He Ye dried leaf liquid extract

Interacts with
212 drugs
970 mg per serving

Lotus is an edible aquatic plant used in food and traditional medicine across Asia, with parts like the seeds, leaves, and flowers taken for digestion...

Wildcrafted He Ye dried leaf liquid extract monograph & interactions

Other (inactive) ingredients: Menstruum. These complete the product’s ingredient list but are not active constituents.

Interaction report

He Ye by Herbal Terra Drug Interactions

Want to check YOUR meds against He Ye?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
212Drugs
212 Moderate

Ingredients driving the most interactions

wildcrafted He Ye dried leaf liquid extract 212

Individual Drug Interactions

The ingredients in He Ye interact with 212 drugs. Click any drug to see the details.

1 of the 1 ingredient in He Ye interact with drugs. Each result below shows which ingredient is responsible. wildcrafted He Ye dried leaf liquid extract

Each ingredient & the kinds of drugs it affects

For each ingredient in He Ye with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

wildcrafted He Ye dried leaf liquid extract3 drug types · 212 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, concurrent use of lotus with other antiplatelet drugs might reduce platelet aggregation and increase the risk of bleeding.
Neferine and isoliensinine, constituents of lotus, have been shown to inhibit platelet aggregation, in vitro. These constituents can inhibit the production of pro-aggregating factors like prostaglandins.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, lotus might have additive effects with antidiabetes drugs and increase the risk of hypoglycemia.
Animal research shows that the ethanolic extract of lotus reduces blood glucose levels and potentiates the effects of injected insulin. Monitor blood glucose levels closely. Dose adjustments might be necessary.

Likelihood Possible Evidence D
Pentobarbital (Nembutal)

Theoretically, taking lotus concomitantly with pentobarbital might increase sedation.
Animal research shows that lotus extract increases pentobarbitone-induced sleeping time. It is not known if this occurs in humans or if this effect occurs with other barbiturates or sedatives.

Likelihood Possible Evidence D
wildcrafted He Ye dried leaf liquid extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for He Ye, from the product label.

Herbal Terra

See all Herbal Terra products
Name
Herbal Terra
Pharmacist Counseling Corner

He Ye by Herbal Terra: Common Questions

Does He Ye by Herbal Terra interact with any medications?
Yes. Based on its ingredients, He Ye has a known interaction with 212 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
He Ye contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take He Ye if I'm pregnant?
Our data doesn't have enough information to say whether it's safe or unsafe in pregnancy. Talk with your doctor or pharmacist about whether it's right for you during pregnancy.
Is He Ye safe to use while breastfeeding?
No, there isn't enough safety data to know either way, so it's best to avoid this supplement while breastfeeding. Check with your doctor or pharmacist if you have questions.
Can He Ye cause allergic reactions?
Yes. Lotus root has caused hives and contact dermatitis in case reports, including a 6-year-old who developed hives after eating it. If you have a known allergy to lotus or related plants, avoid this product.
Does He Ye really work for nausea, insomnia, or weight loss?
We don't have reliable evidence to say. The data we hold shows insufficient evidence to rate this product for those uses or for sore throat, heavy menstrual bleeding, or bleeding.
What's the menstruum in this product?
Menstruum is the liquid used to extract and preserve the lotus leaf's active compounds. It's an inactive ingredient that makes the extract possible.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

He Ye label
Go deeper

The Full Monographs Behind He Ye’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Lotus

Interacts with 212 drugs

Lotus is an edible aquatic plant used in food and traditional medicine across Asia, with parts like the seeds, leaves, and flowers taken for digestion, calm, and overall wellness. Most healt...

Read the full Lotus monograph →
Sources

Sources & How We Checked

He Ye's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lotus 5 references
  1. Yu, J. and Hu, W. S. [Effects of neferine on platelet aggregation in rabbits]. Yao Xue.Xue.Bao. 1997;32(1):1-4.
  2. Yang, J. and Zhou, K. NMR spectroscopic analysis of neferine and isoliensinine. Magn Reson.Chem 2004;42(11):994-997. PubMed
  3. Mukherjee, P. K., Saha, K., Balasubramanian, R., Pal, M., and Saha, B. P. Studies on psychopharmacological effects of Nelumbo nucifera Gaertn. rhizome extract. J Ethnopharmacol. 1996;54(2-3):63-67. PubMed
  4. Mukherjee, P. K., Saha, K., Pal, M., and Saha, B. P. Effect of Nelumbo nucifera rhizome extract on blood sugar level in rats. J Ethnopharmacol. 1997;58(3):207-213. PubMed
  5. Hiraguchi Y, Tokuda R, Gen M, et al. Identification of a novel food allergen in lotus root. Allergol Int. 2018;67(1):141-143. PubMed

See these in context on the Lotus monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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