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Dietary supplement

HerbalNutrition Chamomile Ingredients & Drug Interactions

by The Professional Series

Capsule Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

HerbalNutrition Chamomile is a dietary supplement by The Professional Series with 1 active ingredient. Its ingredients are commonly taken for anxiety and stress, sleep and relaxation, digestive upset.Based on those ingredients, 960 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are German Chamomile herbal extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of HerbalNutrition Chamomile by The Professional Series

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: German chamomile herbal extract. Chamomile is a flowering plant traditionally used for relaxation and sleep support.

The capsule also contains inactive ingredients—gelatin, rice protein, cellulose, and vegetable stearate—which help form and stabilize the capsule.

Does it work?

Insufficient evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Insufficient

There isn't enough reliable clinical evidence to rate this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Stress, anxiety, and relaxation support.
  • We looked for evidence on: Anxiety, Generalized anxiety disorder (GAD), Insomnia, Stress, Sleep quality, Nervous tension.
  • The closest evidence on file: German Chamomile is rated "Insufficient Reliable Evidence To Rate" for Anxiety (Natural Medicines).
  • Also on file: German Chamomile is rated "Insufficient Reliable Evidence To Rate" for Generalized anxiety disorder (GAD), Insomnia.

The evidence we hold doesn't establish that German chamomile works for anxiety, hay fever, sexual dysfunction, ADHD, or loss of appetite from cancer. All of these uses are rated as having insufficient reliable evidence.

If you're considering this product for a specific condition, talk with your pharmacist or doctor about what the science actually supports.

The evidence, ingredient by ingredient German Chamomile

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

German chamomile is generally well tolerated in most adults, but allergic reactions are possible—especially if you're sensitive to ragweed or related plants. Reactions have ranged from mild (itching, sneezing, watery eyes) to severe (anaphylaxis).

Topically, it may cause skin irritation or burning in the mouth. Because there isn't enough reliable safety data, German chamomile should be avoided during pregnancy unless your doctor approves, and you should check with your doctor or pharmacist before using it while breastfeeding.

Side effects, ingredient by ingredient German Chamomile

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — German Chamomile.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 961 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check with your pharmacist if you take warfarin (or other blood thinners), CNS depressants (sedatives, some pain relievers), oral contraceptives, estrogen replacement therapy, or tamoxifen. Also verify any drugs your liver breaks down, since German chamomile may raise their levels.

Use the medication checker on this page to be sure.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with insufficient evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product may be worth considering if you're looking for traditional chamomile support and have no drug interactions. However, because it interacts with blood thinners, sedatives, birth control, hormone therapy, and cancer drugs—plus potentially many others processed by your liver—check your medications with the tool on this page first.

If you're pregnant or nursing, talk to your doctor before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 25, 2012.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about HerbalNutrition Chamomile, straight from the product label.

Brand The Professional Series
Barcode (UPC) 310539461143
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Jul 25, 2012
DSLD ID 10744
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for HerbalNutrition Chamomile by The Professional Series, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
UPC/BARCODE
310539461143
IngredientAmount% DV
German Chamomile herbal extract400 mg--

Other ingredients: Gelatin, Rice Protein, Cellulose, Vegetable Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

ABOUT THIS PRODUCT: Formulated and recommended by health care professionals worldwide, the Professional Series(R) is committed to providing you with the highest quality nutritional supplements available. These formulations are specifically designed to give you the nutritional support you need-an important part of a healthy lifestyle.

All Natural - Easy to Swallow

Nutritional Information

Standardized Herbal Extract

General

Formula #876114

Formula

The German Chamomile (Matricaria recutita L) flower contains bisobolols in the essential oil, plus en-in-dicycloether, matricine, chamazuline, and flavonoids (apigenin and luteoline). This extract is standardized at 1% apigenin and 0.5% essential oil.

Suggested/Recommended/Usage/Directions

SUGGESTED USAGE: As a dietary supplement, adults take 1 capsule daily between meals, or as advised by your health care professional. If digestive irritation occurs, take with meals.

Precautions

Note: If pregnant or nursing consult your health care professional before using.

There have been rare cases of allergic reaction in persons with severe hypersensitivity toward ragweed pollen.

Depressant in large quantities.

KEEP OUT OF REACH OF CHILDREN.

Stop use and consult your health care professional if allergic reactions occur.

Tamper resistant package, do not use if outer seal is missing.

Storage

For optimal storage conditions, store in a cool, dry place. (59(0)-77(0)F/15(0)-25(0)C) (35-65% relative humidity)

FDA Statement of Identity

A Dietary Supplement

See for yourself

HerbalNutrition Chamomile by The Professional Series label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in HerbalNutrition Chamomile by The Professional Series

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.

German Chamomile herbal extract

Interacts with
960 drugs
400 mg per serving Form: Apigenin, Essential {Chamomile} Oil

German chamomile is a widely used herbal remedy taken mainly as a tea for calming, sleep, and digestive complaints. Early research suggests possible b...

German Chamomile herbal extract monograph & interactions

Other (inactive) ingredients: Gelatin, Rice Protein, Cellulose, Vegetable Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

HerbalNutrition Chamomile by The Professional Series Drug Interactions

Want to check YOUR meds against HerbalNutrition Chamomile?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

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960Drugs
925 Moderate 35 Minor

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in HerbalNutrition Chamomile with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

German Chamomile herbal extract9 drug types · 960 drugs

Cns Depressants

Theoretically, German chamomile might have additive effects when used with CNS depressants.
German chamomile has mild sedative effects. Theoretically, concomitant use with drugs with sedative properties can cause additive effects and side effects.

Likelihood Possible Evidence D
Contraceptive Drugs

Theoretically, large amounts of German chamomile might reduce the effectiveness of oral contraceptives.
In vitro, German chamomile has demonstrated antiestrogenic activity. Theoretically, concomitant use of large amounts of German chamomile might interfere with contraceptive drugs through competition for estrogen receptors.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, German chamomile might inhibit CYP2C9 and increase levels of drugs metabolized by these enzymes.
In vitro evidence shows that German chamomile might inhibit CYP2C9. So far, this interaction has not been reported in humans. However, there might be an increase in the levels of drugs metabolized by CYP2C9 in patients taking German chamomile.

Likelihood Possible Evidence D
Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, German chamomile might inhibit CYP2D6 and increase levels of drugs metabolized by these enzymes.
In vitro evidence shows that German chamomile might inhibit CYP2D6. So far, this interaction has not been reported in humans. However, there might be an increase in the levels of drugs metabolized by CYP2D6 in patients taking German chamomile.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, German chamomile might inhibit CYP3A4 and increase levels of drugs metabolized by these enzymes.
In vitro evidence shows that German chamomile might inhibit CYP3A4. So far, this interaction has not been reported in humans. However, there might be an increase in the levels of drugs metabolized by CYP3A4 in patients taking German chamomile.

Likelihood Possible Evidence D
Estrogens

Theoretically, large amounts of German chamomile might reduce the effectiveness of estrogens.
In vitro, German chamomile has demonstrated antiestrogenic activity. Theoretically, large amounts of German chamomile might interfere with hormone replacement therapy through competition for estrogen receptors.

Likelihood Possible Evidence D
Tamoxifen (Nolvadex)

Theoretically, large amounts of German chamomile might interfere with the activity of tamoxifen.
In vitro, German chamomile has demonstrated antiestrogenic activity.

Likelihood Possible Evidence D
Warfarin (Coumadin)

German chamomile might increase the effects of warfarin and increase the risk of bleeding.
In one case, a 70-year-old female taking warfarin developed retroperitoneal hematoma and bilateral recti muscle bleeding along with an INR of 7.9 following ingestion of German chamomile tea 4-5 cups daily and use of a topical chamomile-based lotion applied 4-5 times daily.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, German chamomile might inhibit CYP1A2 and increase levels of drugs metabolized by these enzymes.
In vitro and animal research shows that German chamomile might inhibit CYP1A2. So far, this interaction has not been reported in humans. However, there might be an increase in the levels of drugs metabolized by CYP1A2 in patients taking German chamomile.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for HerbalNutrition Chamomile, from the product label.

The Professional Series

See all The Professional Series products
Name
The Professional Series(R)
Street Address
600 Boyce Road
City
Robinson Twp.
State
PA
ZipCode
15205
Pharmacist Counseling Corner

HerbalNutrition Chamomile by The Professional Series: Common Questions

Does HerbalNutrition Chamomile by The Professional Series interact with any medications?
Yes. Based on its ingredients, HerbalNutrition Chamomile has a known interaction with 960 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
HerbalNutrition Chamomile contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm allergic to ragweed?
You should be cautious. German chamomile can trigger allergic reactions in people sensitive to ragweed and related plants, sometimes severely. If you have a ragweed allergy, check with your doctor or pharmacist before using this product.
Is chamomile safe during pregnancy?
There isn't enough reliable safety data, so it's best avoided during pregnancy unless your doctor specifically approves. Talk to your doctor or midwife if you're pregnant or planning to become pregnant.
Can I use this while breastfeeding?
Limited safety data exist for breastfeeding, so check with your doctor or pharmacist first. They can help you weigh the risks and benefits for your situation.
What side effects might I notice?
Allergic reactions are the main concern, ranging from itching and watery eyes to severe reactions in rare cases. If taken as a tea, some people report nausea or a burning sensation in the mouth. If you notice any unusual symptoms, stop and contact your pharmacist.
Does this product actually work for anxiety or sleep?
The evidence we hold isn't strong enough to confirm that chamomile works for anxiety or other uses listed here. We have insufficient reliable evidence for all of them, so talk with your doctor about whether it makes sense for your needs.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

HerbalNutrition Chamomile label
Sources

Sources & How We Checked

HerbalNutrition Chamomile's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 15 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

German Chamomile 15 references
  1. Subiza J, Subiza JL, Hinojosa M, et al. Anaphylactic reaction after the ingestion of chamomile tea; a study of cross-reactivity with other composite pollens. J Allergy Clin Immunol 1989;84:353-8. PubMed
  2. Budzinski JW, Foster BC, Vandenhoek S, Arnason JT. An in vitro evaluation of human cytochrome P450 3A4 inhibition by selected commercial herbal extracts and tinctures. Phytomedicine 2000;7:273-82. PubMed
  3. Viola H, Wasowski C, Levi de Stein M, et al. Apigenin, a component of Matricaria recutita flowers, is a central benzodiazepine receptors-ligand with anxiolytic effects. Planta Med 1995;61:213-6.
  4. van Ketel WG. Allergy to Matricaria chamomilla. Contact Dermatitis 1982;8:143. PubMed
  5. van Ketel WG. Allergy to Matricaria chamomilla. Contact Dermatitis 1987;16:50-1. PubMed
  6. Hormann HP, Korting HC. Evidence for the efficacy and safety of topical herbal drugs in dermatology: part I: anti-inflammatory agents. Phytomedicine 1994;1:161-71. PubMed
  7. Avallone R, Zanoli P, Puia G, et al. Pharmacological profile of apigenin, a flavonoid isolated from Matricaria chamomilla. Biochem Pharmacol 2000;59:1387-94. PubMed
  8. Kassi E, Papoutsi Z, Fokialakis N, et al. Greek plant extracts exhibit selective estrogen receptor modulator (SERM)-like properties. J Agric Food Chem 2004;52:6956-61. PubMed
  9. Maliakal PP, Wanwimolruk S. Effect of herbal teas on hepatic drug metabolizing enzymes in rats. J Pharm Pharmacol 2001;53:1323-9. PubMed
  10. Segal R, Pilote L. Warfarin interaction with Matricaria chamomilla. CMAJ 2006;174:1281-2. PubMed
  11. Loggia RD, Traversa U, Scarcia V, et al. Depressive effects of Chamomilla recutita (L.) Rausch, tubular flowers, on central nervous system in mice. Pharmacol Res Commun 1982;14(2):153-162. PubMed
  12. Ganzera M, Schneider P, Stuppner H. Inhibitory effects of the essential oil of chamomile (Matricaria recutita L.) and its major constituents on human cytochrome P450 enzymes. Life Sci 2006;78(8):856-861. PubMed
  13. Benito P, Rodríguez-Perez R, García F, Juste S, Moneo I, Caballero ML. Occupational allergic rhinoconjunctivitis induced by Matricaria chamomilla with tolerance of chamomile tea. J Investig Allergol Clin Immunol. 2014;24(5):369-70. No abstract available.
  14. Braga FT, Santos AC, Bueno PC, et al. Use of Chamomilla recutita in the prevention and treatment of oral mucositis in patients undergoing hematopoietic stem cell transplantation: a randomized, controlled, phase II clinical trial. Cancer Nurs 2015;38(4):32 PubMed
  15. Sarris J, Ravindran A, Yatham LN, et al. Clinician guidelines for the treatment of psychiatric disorders with nutraceuticals and phytoceuticals: The World Federation of Societies of Biological Psychiatry (WFSBP) and Canadian Network for Mood and Anxiety T

See these in context on the German Chamomile monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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