HerbalNutrition Chamomile Ingredients & Drug Interactions
What is this page for?
First and foremost: checking HerbalNutrition Chamomile against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
HerbalNutrition Chamomile is a dietary supplement by The Professional Series with 1 active ingredient. Its ingredients are commonly taken for anxiety and stress, sleep and relaxation, digestive upset.Based on those ingredients, 960 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are German Chamomile herbal extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against HerbalNutrition Chamomile by The Professional Series
Ask about any prescription or over-the-counter medication and we check it for interactions with HerbalNutrition Chamomile by The Professional Series — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of HerbalNutrition Chamomile by The Professional Series
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: German chamomile herbal extract. Chamomile is a flowering plant traditionally used for relaxation and sleep support.
The capsule also contains inactive ingredients—gelatin, rice protein, cellulose, and vegetable stearate—which help form and stabilize the capsule.
Does it work?
Insufficient evidence
The evidence we hold doesn't establish that German chamomile works for anxiety, hay fever, sexual dysfunction, ADHD, or loss of appetite from cancer. All of these uses are rated as having insufficient reliable evidence.
If you're considering this product for a specific condition, talk with your pharmacist or doctor about what the science actually supports.
How safe is it?
Well-documented data
German chamomile is generally well tolerated in most adults, but allergic reactions are possible—especially if you're sensitive to ragweed or related plants. Reactions have ranged from mild (itching, sneezing, watery eyes) to severe (anaphylaxis).
Topically, it may cause skin irritation or burning in the mouth. Because there isn't enough reliable safety data, German chamomile should be avoided during pregnancy unless your doctor approves, and you should check with your doctor or pharmacist before using it while breastfeeding.
Meds to double-check
Moderate interaction found
Before taking this product, double-check with your pharmacist if you take warfarin (or other blood thinners), CNS depressants (sedatives, some pain relievers), oral contraceptives, estrogen replacement therapy, or tamoxifen. Also verify any drugs your liver breaks down, since German chamomile may raise their levels.
Use the medication checker on this page to be sure.
The bottom line
Scorecard at a glanceFully disclosed formula with insufficient evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This product may be worth considering if you're looking for traditional chamomile support and have no drug interactions. However, because it interacts with blood thinners, sedatives, birth control, hormone therapy, and cancer drugs—plus potentially many others processed by your liver—check your medications with the tool on this page first.
If you're pregnant or nursing, talk to your doctor before starting.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 25, 2012.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about HerbalNutrition Chamomile, straight from the product label.
| Brand | The Professional Series |
|---|---|
| Barcode (UPC) | 310539461143 |
| Net contents | 60 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Jul 25, 2012 |
| DSLD ID | 10744 |
| Product type | Botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for HerbalNutrition Chamomile by The Professional Series, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| German Chamomile herbal extract | 400 mg | -- |
Other ingredients: Gelatin, Rice Protein, Cellulose, Vegetable Stearate
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
ABOUT THIS PRODUCT: Formulated and recommended by health care professionals worldwide, the Professional Series(R) is committed to providing you with the highest quality nutritional supplements available. These formulations are specifically designed to give you the nutritional support you need-an important part of a healthy lifestyle.
All Natural - Easy to Swallow
Nutritional Information
Standardized Herbal Extract
General
Formula #876114
Formula
The German Chamomile (Matricaria recutita L) flower contains bisobolols in the essential oil, plus en-in-dicycloether, matricine, chamazuline, and flavonoids (apigenin and luteoline). This extract is standardized at 1% apigenin and 0.5% essential oil.
Suggested/Recommended/Usage/Directions
SUGGESTED USAGE: As a dietary supplement, adults take 1 capsule daily between meals, or as advised by your health care professional. If digestive irritation occurs, take with meals.
Precautions
Note: If pregnant or nursing consult your health care professional before using.
There have been rare cases of allergic reaction in persons with severe hypersensitivity toward ragweed pollen.
Depressant in large quantities.
KEEP OUT OF REACH OF CHILDREN.
Stop use and consult your health care professional if allergic reactions occur.
Tamper resistant package, do not use if outer seal is missing.
Storage
For optimal storage conditions, store in a cool, dry place. (59(0)-77(0)F/15(0)-25(0)C) (35-65% relative humidity)
FDA Statement of Identity
A Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
HerbalNutrition Chamomile by The Professional Series label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in HerbalNutrition Chamomile by The Professional Series
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.
German Chamomile herbal extract
Interacts with960 drugs
German chamomile is a widely used herbal remedy taken mainly as a tea for calming, sleep, and digestive complaints. Early research suggests possible b...
German Chamomile herbal extract monograph & interactionsOther (inactive) ingredients: Gelatin, Rice Protein, Cellulose, Vegetable Stearate. These complete the product’s ingredient list but are not active constituents.
HerbalNutrition Chamomile by The Professional Series Drug Interactions
HelloPharmacist Interaction Report
HerbalNutrition Chamomile by The Professional Series contains German chamomile, which has documented interactions with several medication types.
The single most serious interaction involves warfarin (a blood thinner used to prevent clots): German chamomile may increase warfarin's effects and raise the risk of bleeding. One case reported a patient on warfarin who developed serious internal bleeding after drinking 4–5 cups of chamomile tea daily and using a topical chamomile lotion.
Read the full breakdown — every affected drug type, severity by severity
German chamomile also interacts with CNS depressants—medications that slow brain activity, such as sedatives and some pain relievers—through additive drowsiness and related side effects. It may inhibit three liver enzymes (CYP2D6, CYP2C9, and CYP3A4) that break down many drugs, potentially raising their blood levels; this hasn't been reported in humans yet, but it's a theoretical risk.
Additionally, large amounts of German chamomile may reduce the effectiveness of oral contraceptives and estrogen replacement therapy by interfering with how your body uses these hormones, and may interfere with tamoxifen (a cancer drug).
Altogether, these interactions span 950 individual medications. Because so many drugs are affected, use the medication checker on this page to verify your exact prescriptions before starting this product.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against HerbalNutrition Chamomile?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in HerbalNutrition Chamomile interact with 960 drugs. Click any drug to see the details.
1 of the 1 ingredient in HerbalNutrition Chamomile interact with drugs. Each result below shows which ingredient is responsible. German Chamomile herbal extract
Ado-trastuzumab EmtansineKadcyla
How Ado-trastuzumab Emtansine interacts with HerbalNutrition Chamomile — through 1 ingredient. Tap an ingredient for the detail:
German Chamomile Herbal ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, German chamomile might inhibit CYP3A4 and increase levels of drugs metabolized by these enzymes.
Read the full German Chamomile Herbal Extract + Ado-trastuzumab Emtansine interactionAbemaciclibVerzenio
How Abemaciclib interacts with HerbalNutrition Chamomile — through 1 ingredient. Tap an ingredient for the detail:
German Chamomile Herbal ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, German chamomile might inhibit CYP3A4 and increase levels of drugs metabolized by these enzymes.
Read the full German Chamomile Herbal Extract + Abemaciclib interactionAbiraterone
How Abiraterone interacts with HerbalNutrition Chamomile — through 1 ingredient. Tap an ingredient for the detail:
German Chamomile Herbal ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, German chamomile might inhibit CYP3A4 and increase levels of drugs metabolized by these enzymes.
Read the full German Chamomile Herbal Extract + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with HerbalNutrition Chamomile — through 1 ingredient. Tap an ingredient for the detail:
German Chamomile Herbal ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, German chamomile might inhibit CYP3A4 and increase levels of drugs metabolized by these enzymes.
Read the full German Chamomile Herbal Extract + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with HerbalNutrition Chamomile — through 1 ingredient. Tap an ingredient for the detail:
German Chamomile Herbal ExtractCytochrome P450 2c9 (cyp2c9) Substrates Moderate
Interaction Summary
Theoretically, German chamomile might inhibit CYP2C9 and increase levels of drugs metabolized by these enzymes.
Read the full German Chamomile Herbal Extract + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with HerbalNutrition Chamomile — through 1 ingredient. Tap an ingredient for the detail:
German Chamomile Herbal ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, German chamomile might inhibit CYP3A4 and increase levels of drugs metabolized by these enzymes.
Read the full German Chamomile Herbal Extract + Acalabrutinib interactionAcepromazineAtravet
How Acepromazine interacts with HerbalNutrition Chamomile — through 1 ingredient. Tap an ingredient for the detail:
German Chamomile Herbal ExtractCns Depressants Moderate
Interaction Summary
Theoretically, German chamomile might have additive effects when used with CNS depressants.
Read the full German Chamomile Herbal Extract + Acepromazine interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with HerbalNutrition Chamomile — through 1 ingredient. Tap an ingredient for the detail:
German Chamomile Herbal ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, German chamomile might inhibit CYP1A2 and increase levels of drugs metabolized by these enzymes.
Read the full German Chamomile Herbal Extract + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with HerbalNutrition Chamomile — through 1 ingredient. Tap an ingredient for the detail:
German Chamomile Herbal ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, German chamomile might inhibit CYP1A2 and increase levels of drugs metabolized by these enzymes.
Read the full German Chamomile Herbal Extract + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with HerbalNutrition Chamomile — through 1 ingredient. Tap an ingredient for the detail:
German Chamomile Herbal ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cns Depressants +2 Moderate
Interaction Summary
Theoretically, German chamomile might inhibit CYP3A4 and increase levels of drugs metabolized by these enzymes.
Read the full German Chamomile Herbal Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with HerbalNutrition Chamomile — through 1 ingredient. Tap an ingredient for the detail:
German Chamomile Herbal ExtractCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, German chamomile might inhibit CYP2D6 and increase levels of drugs metabolized by these enzymes.
Read the full German Chamomile Herbal Extract + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with HerbalNutrition Chamomile — through 1 ingredient. Tap an ingredient for the detail:
German Chamomile Herbal ExtractCns Depressants, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, German chamomile might have additive effects when used with CNS depressants.
Read the full German Chamomile Herbal Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with HerbalNutrition Chamomile — through 1 ingredient. Tap an ingredient for the detail:
German Chamomile Herbal ExtractCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +2 Moderate
Interaction Summary
Theoretically, German chamomile might inhibit CYP2D6 and increase levels of drugs metabolized by these enzymes.
Read the full German Chamomile Herbal Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with HerbalNutrition Chamomile — through 1 ingredient. Tap an ingredient for the detail:
German Chamomile Herbal ExtractCns Depressants, Cytochrome P450 2d6 (cyp2d6) Substrates +2 Moderate
Interaction Summary
Theoretically, German chamomile might have additive effects when used with CNS depressants.
Read the full German Chamomile Herbal Extract + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with HerbalNutrition Chamomile — through 1 ingredient. Tap an ingredient for the detail:
German Chamomile Herbal ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cns Depressants +2 Moderate
Interaction Summary
Theoretically, German chamomile might inhibit CYP3A4 and increase levels of drugs metabolized by these enzymes.
Read the full German Chamomile Herbal Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with HerbalNutrition Chamomile — through 1 ingredient. Tap an ingredient for the detail:
German Chamomile Herbal ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +2 Moderate
Interaction Summary
Theoretically, German chamomile might inhibit CYP1A2 and increase levels of drugs metabolized by these enzymes.
Read the full German Chamomile Herbal Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with HerbalNutrition Chamomile — through 1 ingredient. Tap an ingredient for the detail:
German Chamomile Herbal ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, German chamomile might inhibit CYP1A2 and increase levels of drugs metabolized by these enzymes.
Read the full German Chamomile Herbal Extract + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with HerbalNutrition Chamomile — through 1 ingredient. Tap an ingredient for the detail:
German Chamomile Herbal ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, German chamomile might inhibit CYP3A4 and increase levels of drugs metabolized by these enzymes.
Read the full German Chamomile Herbal Extract + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with HerbalNutrition Chamomile — through 1 ingredient. Tap an ingredient for the detail:
German Chamomile Herbal ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, German chamomile might inhibit CYP1A2 and increase levels of drugs metabolized by these enzymes.
Read the full German Chamomile Herbal Extract + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with HerbalNutrition Chamomile — through 1 ingredient. Tap an ingredient for the detail:
German Chamomile Herbal ExtractCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +2 Moderate
Interaction Summary
Theoretically, German chamomile might inhibit CYP2D6 and increase levels of drugs metabolized by these enzymes.
Read the full German Chamomile Herbal Extract + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with HerbalNutrition Chamomile — through 1 ingredient. Tap an ingredient for the detail:
German Chamomile Herbal ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +1 Moderate
Interaction Summary
Theoretically, German chamomile might inhibit CYP1A2 and increase levels of drugs metabolized by these enzymes.
Read the full German Chamomile Herbal Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with HerbalNutrition Chamomile — through 1 ingredient. Tap an ingredient for the detail:
German Chamomile Herbal ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, German chamomile might inhibit CYP3A4 and increase levels of drugs metabolized by these enzymes.
Read the full German Chamomile Herbal Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with HerbalNutrition Chamomile — through 1 ingredient. Tap an ingredient for the detail:
German Chamomile Herbal ExtractCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, German chamomile might inhibit CYP2D6 and increase levels of drugs metabolized by these enzymes.
Read the full German Chamomile Herbal Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with HerbalNutrition Chamomile — through 1 ingredient. Tap an ingredient for the detail:
German Chamomile Herbal ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +1 Moderate
Interaction Summary
Theoretically, German chamomile might inhibit CYP1A2 and increase levels of drugs metabolized by these enzymes.
Read the full German Chamomile Herbal Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, SalicylamideRhinogesic GG
How Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interacts with HerbalNutrition Chamomile — through 1 ingredient. Tap an ingredient for the detail:
German Chamomile Herbal ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, German chamomile might inhibit CYP1A2 and increase levels of drugs metabolized by these enzymes.
Read the full German Chamomile Herbal Extract + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylephrineAlka-Seltzer PLUS, Histex SR, Protid
How Acetaminophen, Chlorpheniramine, Phenylephrine interacts with HerbalNutrition Chamomile — through 1 ingredient. Tap an ingredient for the detail:
German Chamomile Herbal ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, German chamomile might inhibit CYP1A2 and increase levels of drugs metabolized by these enzymes.
Read the full German Chamomile Herbal Extract + Acetaminophen, Chlorpheniramine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, Phenylephrine, SalicylamideRhinogesic, Rhinogesic JR
How Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interacts with HerbalNutrition Chamomile — through 1 ingredient. Tap an ingredient for the detail:
German Chamomile Herbal ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, German chamomile might inhibit CYP1A2 and increase levels of drugs metabolized by these enzymes.
Read the full German Chamomile Herbal Extract + Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylpropanolamineAlumadrine, Conex, Sinadrin Max Strength, Sinulin
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine interacts with HerbalNutrition Chamomile — through 1 ingredient. Tap an ingredient for the detail:
German Chamomile Herbal ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, German chamomile might inhibit CYP1A2 and increase levels of drugs metabolized by these enzymes.
Read the full German Chamomile Herbal Extract + Acetaminophen, Chlorpheniramine, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, OpiumHista-Derfule
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interacts with HerbalNutrition Chamomile — through 1 ingredient. Tap an ingredient for the detail:
German Chamomile Herbal ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, German chamomile might inhibit CYP3A4 and increase levels of drugs metabolized by these enzymes.
Read the full German Chamomile Herbal Extract + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, PhenyltoloxamineNorel Plus
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interacts with HerbalNutrition Chamomile — through 1 ingredient. Tap an ingredient for the detail:
German Chamomile Herbal ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, German chamomile might inhibit CYP3A4 and increase levels of drugs metabolized by these enzymes.
Read the full German Chamomile Herbal Extract + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in HerbalNutrition Chamomile with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
German Chamomile herbal extract
Cns Depressants
Theoretically, German chamomile might have additive effects when used with CNS depressants.
German chamomile has mild sedative effects. Theoretically, concomitant use with drugs with sedative properties can cause additive effects and side effects.
Contraceptive Drugs
Theoretically, large amounts of German chamomile might reduce the effectiveness of oral contraceptives.
In vitro, German chamomile has demonstrated antiestrogenic activity. Theoretically, concomitant use of large amounts of German chamomile might interfere with contraceptive drugs through competition for estrogen receptors.
Cytochrome P450 2C9 (Cyp2C9) Substrates
Theoretically, German chamomile might inhibit CYP2C9 and increase levels of drugs metabolized by these enzymes.
In vitro evidence shows that German chamomile might inhibit CYP2C9. So far, this interaction has not been reported in humans. However, there might be an increase in the levels of drugs metabolized by CYP2C9 in patients taking German chamomile.
Cytochrome P450 2D6 (Cyp2D6) Substrates
Theoretically, German chamomile might inhibit CYP2D6 and increase levels of drugs metabolized by these enzymes.
In vitro evidence shows that German chamomile might inhibit CYP2D6. So far, this interaction has not been reported in humans. However, there might be an increase in the levels of drugs metabolized by CYP2D6 in patients taking German chamomile.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, German chamomile might inhibit CYP3A4 and increase levels of drugs metabolized by these enzymes.
In vitro evidence shows that German chamomile might inhibit CYP3A4. So far, this interaction has not been reported in humans. However, there might be an increase in the levels of drugs metabolized by CYP3A4 in patients taking German chamomile.
Estrogens
Theoretically, large amounts of German chamomile might reduce the effectiveness of estrogens.
In vitro, German chamomile has demonstrated antiestrogenic activity. Theoretically, large amounts of German chamomile might interfere with hormone replacement therapy through competition for estrogen receptors.
Tamoxifen (Nolvadex)
Theoretically, large amounts of German chamomile might interfere with the activity of tamoxifen.
In vitro, German chamomile has demonstrated antiestrogenic activity.
Warfarin (Coumadin)
German chamomile might increase the effects of warfarin and increase the risk of bleeding.
In one case, a 70-year-old female taking warfarin developed retroperitoneal hematoma and bilateral recti muscle bleeding along with an INR of 7.9 following ingestion of German chamomile tea 4-5 cups daily and use of a topical chamomile-based lotion applied 4-5 times daily.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, German chamomile might inhibit CYP1A2 and increase levels of drugs metabolized by these enzymes.
In vitro and animal research shows that German chamomile might inhibit CYP1A2. So far, this interaction has not been reported in humans. However, there might be an increase in the levels of drugs metabolized by CYP1A2 in patients taking German chamomile.
Brand information
Manufacturer and brand details for HerbalNutrition Chamomile, from the product label.
The Professional Series
See all The Professional Series products- Name
- The Professional Series(R)
- Street Address
- 600 Boyce Road
- City
- Robinson Twp.
- State
- PA
- ZipCode
- 15205
HerbalNutrition Chamomile by The Professional Series: Common Questions
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind HerbalNutrition Chamomile’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
HerbalNutrition Chamomile's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 15 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
German Chamomile 15 references
- Subiza J, Subiza JL, Hinojosa M, et al. Anaphylactic reaction after the ingestion of chamomile tea; a study of cross-reactivity with other composite pollens. J Allergy Clin Immunol 1989;84:353-8. PubMed
- Budzinski JW, Foster BC, Vandenhoek S, Arnason JT. An in vitro evaluation of human cytochrome P450 3A4 inhibition by selected commercial herbal extracts and tinctures. Phytomedicine 2000;7:273-82. PubMed
- Viola H, Wasowski C, Levi de Stein M, et al. Apigenin, a component of Matricaria recutita flowers, is a central benzodiazepine receptors-ligand with anxiolytic effects. Planta Med 1995;61:213-6.
- van Ketel WG. Allergy to Matricaria chamomilla. Contact Dermatitis 1982;8:143. PubMed
- van Ketel WG. Allergy to Matricaria chamomilla. Contact Dermatitis 1987;16:50-1. PubMed
- Hormann HP, Korting HC. Evidence for the efficacy and safety of topical herbal drugs in dermatology: part I: anti-inflammatory agents. Phytomedicine 1994;1:161-71. PubMed
- Avallone R, Zanoli P, Puia G, et al. Pharmacological profile of apigenin, a flavonoid isolated from Matricaria chamomilla. Biochem Pharmacol 2000;59:1387-94. PubMed
- Kassi E, Papoutsi Z, Fokialakis N, et al. Greek plant extracts exhibit selective estrogen receptor modulator (SERM)-like properties. J Agric Food Chem 2004;52:6956-61. PubMed
- Maliakal PP, Wanwimolruk S. Effect of herbal teas on hepatic drug metabolizing enzymes in rats. J Pharm Pharmacol 2001;53:1323-9. PubMed
- Segal R, Pilote L. Warfarin interaction with Matricaria chamomilla. CMAJ 2006;174:1281-2. PubMed
- Loggia RD, Traversa U, Scarcia V, et al. Depressive effects of Chamomilla recutita (L.) Rausch, tubular flowers, on central nervous system in mice. Pharmacol Res Commun 1982;14(2):153-162. PubMed
- Ganzera M, Schneider P, Stuppner H. Inhibitory effects of the essential oil of chamomile (Matricaria recutita L.) and its major constituents on human cytochrome P450 enzymes. Life Sci 2006;78(8):856-861. PubMed
- Benito P, Rodríguez-Perez R, García F, Juste S, Moneo I, Caballero ML. Occupational allergic rhinoconjunctivitis induced by Matricaria chamomilla with tolerance of chamomile tea. J Investig Allergol Clin Immunol. 2014;24(5):369-70. No abstract available.
- Braga FT, Santos AC, Bueno PC, et al. Use of Chamomilla recutita in the prevention and treatment of oral mucositis in patients undergoing hematopoietic stem cell transplantation: a randomized, controlled, phase II clinical trial. Cancer Nurs 2015;38(4):32 PubMed
- Sarris J, Ravindran A, Yatham LN, et al. Clinician guidelines for the treatment of psychiatric disorders with nutraceuticals and phytoceuticals: The World Federation of Societies of Biological Psychiatry (WFSBP) and Canadian Network for Mood and Anxiety T
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC