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Dietary supplement

High Strength Pumpkin Seed 2000 mg Ingredients & Drug Interactions

by Simply Supplements

Capsule Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

High Strength Pumpkin Seed 2000 mg is a dietary supplement by Simply Supplements with 1 active ingredient. Its ingredients are commonly taken for benign prostatic hyperplasia (bph) symptoms, overactive bladder, eye and skin health (vitamin a source).Based on those ingredients, 1 medication has a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Pumpkin. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of High Strength Pumpkin Seed 2000 mg by Simply Supplements

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: pumpkin seed at 2000 mg per serving. The supplement also includes inactive ingredients (maltodextrin, gelatin, and magnesium stearate), which are fillers and capsule materials that help hold the product together and make it easier to swallow.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: prostate and urinary health support.
  • We looked for evidence on: Benign prostatic hyperplasia (BPH), Overactive bladder, urinary frequency, nocturia.
  • The strongest evidence on file: Pumpkin is rated "Possibly Effective" for Benign prostatic hyperplasia (BPH) (Natural Medicines).
  • Also on file: Pumpkin is rated "Insufficient Reliable Evidence To Rate" for Overactive bladder.

The evidence for pumpkin seed in benign prostatic hyperplasia (BPH)—enlarged prostate—is rated as possibly effective, meaning some research suggests a benefit but more study is needed. For androgenic alopecia (male-pattern hair loss), interstitial cystitis (bladder inflammation), intestinal parasite infection, and urinary tract infections, the evidence we hold is insufficient to rate whether it works.

That doesn't mean it doesn't; it means the data isn't robust enough yet to say either way.

The evidence, ingredient by ingredient Pumpkin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Pumpkin as a food is generally well tolerated. The safety of concentrated seed supplements in adults is generally considered good, though long-term data is limited.

The most common side effects in studies and reports are abdominal discomfort, diarrhea, nausea, and vomiting. Rarely, anaphylaxis (a severe allergic reaction) has been reported.

There are also two case reports of temporary hair loss following consumption of bitter-tasting pumpkin or squash, attributed to high levels of cucurbitacin, a natural toxin found in wild varieties. For pregnancy and breastfeeding, data on concentrated pumpkin seed supplements is not well studied.

If you are pregnant or breastfeeding, talk with your doctor or pharmacist about whether this product is right for you—they can help you weigh the unknowns.

Side effects, ingredient by ingredient Pumpkin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Pumpkin.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: lithium.
  • For scale: 1 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take lithium for mood disorders, you must confirm with your doctor or pharmacist before using this product. Pumpkin may slow how your body clears lithium, potentially raising its level to unsafe ranges.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

High Strength Pumpkin Seed may be worth considering if you have an enlarged prostate and want to explore a plant-based option, though evidence is modest. If you take lithium, check with your doctor or pharmacist before starting—this product could affect how your body handles the medication.

For anyone else, mention it to your healthcare provider if you have any ongoing health concerns or take other medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 24, 2017.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about High Strength Pumpkin Seed 2000 mg, straight from the product label.

Brand Simply Supplements
Barcode (UPC) 5060370564156
Net contents 180 Capsule(s)
Market status On market
Date entered into DSLD Feb 24, 2017
DSLD ID 70759
Product type Botanical
Supplement form Capsule
Dietary claims / uses Nutrient, All Other
Intended target group(s) Adult Male (18-50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for High Strength Pumpkin Seed 2000 mg by Simply Supplements, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
UPC/BARCODE
5060370564156
IngredientAmount% DV
Pumpkin100 mg--

Other ingredients: Maltodextrin, Gelatin, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

Important Information If you are taking any prescription medication, you have a medical condition or you have specific concerns about the suitability of our products, always consult your GP or Pharmacist prior to taking supplements.

Do not exceed stated dose.

Keep away from children at all times.

Do not use if seal is broken.

Pregnant or lactating women should consult a doctor before using this product.

Food supplement: This product should not be used as a substitute for a varied diet. Not suitable for vegetarians.

Storage

Store in a cool dry place.

Suggested Daily Intake Take one to two capsules daily as a food supplement or as directed by a healthcare professional.

General Statements

Image is for illustration purposes only.

EasyGest capsules ~ Easy to swallow ~ Easy to absorb ~ Easy to digest ~ No product odour ~ No bad taste

AutoDespatch Save 10% and get free P&P on all repeat orders by having your favourite supplements conveniently scheduled and delivered automatically with our unique AutoDespatch system. Same day despatch We will ensure your order is despatched on the day of receipt (when placed before 12.30pm) and that all orders placed after 12.30pm are despatched on the next working day. All sent 1st class!

General

PriceMatch guarantee! If you buy from us and then see the same product cheaper elsewhere we will refund the difference plus 10%!

E622

Formula

Packed with high levels of zinc magnesium, calcium, iron and vitamins.

An important supplement for men

Product Information A supplement exclusively for men which may help prostate health and act as a prevention remedy for the future.

Seals/Symbols

Quality Assured

See for yourself

High Strength Pumpkin Seed 2000 mg by Simply Supplements label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in High Strength Pumpkin Seed 2000 mg by Simply Supplements

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.

Pumpkin

Interacts with
1 drug
100 mg per serving

Pumpkin is a nutritious squash, and its seeds and seed oil are the parts most often used as supplements, mainly for urinary and prostate symptoms. The...

Pumpkin monograph & interactions

Other (inactive) ingredients: Maltodextrin, Gelatin, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

High Strength Pumpkin Seed 2000 mg by Simply Supplements Drug Interactions

Want to check YOUR meds against High Strength Pumpkin Seed 2000 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
1Drugs
1 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in High Strength Pumpkin Seed 2000 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Pumpkin1 drug type · 1 drug

Lithium

Pumpkin might reduce excretion and increase levels of lithium.
Pumpkin is thought to have diuretic properties. Theoretically, this might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Probable Evidence D
The maker

Brand information

Manufacturer and brand details for High Strength Pumpkin Seed 2000 mg, from the product label.

Simply Supplements

See all Simply Supplements products
Name
Simply Supplements
Street Address
PO Box 1330
City
Peterborough
ZipCode
PE2 2PW
Phone Number
0800 988 0292
Pharmacist Counseling Corner

High Strength Pumpkin Seed 2000 mg by Simply Supplements: Common Questions

Does High Strength Pumpkin Seed 2000 mg by Simply Supplements interact with any medications?
Yes. Based on its ingredients, High Strength Pumpkin Seed 2000 mg has a known interaction with 1 medication. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
High Strength Pumpkin Seed 2000 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
There isn't enough safety data on concentrated pumpkin seed supplements in pregnancy or breastfeeding to know either way. Talk with your doctor or pharmacist before starting—they can give you personalized advice based on your situation.
What are the most common side effects?
Abdominal discomfort, diarrhea, nausea, and vomiting are the most common side effects reported in studies and real-world use. These are usually mild. Rarely, anaphylaxis (a severe allergic reaction) has been reported.
Does pumpkin seed work for hair loss?
The evidence we have on pumpkin seed for androgenic alopecia (male-pattern hair loss) is insufficient to rate—we don't have enough reliable data yet to say whether it helps or doesn't.
Why is there a warning about bitter-tasting pumpkin?
Two case reports describe temporary hair loss after eating bitter pumpkin or squash, likely due to high levels of a natural toxin called cucurbitacin found in wild varieties. This product is a processed supplement, so the risk is lower, but it's worth knowing.
What does pumpkin seed do for the prostate?
Pumpkin seed is possibly effective for benign prostatic hyperplasia (BPH), which is an enlarged prostate that can cause urinary symptoms. That means some research suggests a benefit, but more evidence is still needed.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if High Strength Pumpkin Seed 2000 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

High Strength Pumpkin Seed 2000 mg label
Go deeper

The Full Monographs Behind High Strength Pumpkin Seed 2000 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

High Strength Pumpkin Seed 2000 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Pumpkin 5 references
  1. Marks L, Partin AW, Epstein JI, et al. Effects of a saw palmetto herbal blend in men with symptomatic benign prostatic hyperplasia. J Urol 2000;163:1451-6. DOI
  2. Cho YH, Lee SY, Jeong DW, et al. Effect of pumpkin seed oil on hair growth in men with androgenetic alopecia: a randomized, double-blind, placebo-controlled trial. Evid Based Complement Alternat Med 2014;2014:549721. PubMed
  3. Vahlensieck W, Theurer C, Pfitzer E, Patz B, Banik N, Engelmann U. Effects of pumpkin seed in men with lower urinary tract symptoms due to benign prostatic hyperplasia in the one-year, randomized, placebo-controlled GRANU study. Urol Int 2015;94(3):286-95 PubMed
  4. Assouly P. Hair loss associated with cucurbit poisoning. JAMA Dermatol. 2018 May 1;154(5):617-618. PubMed
  5. Gawryjolek J, Ludwig H, Zbikowska-Götz M, Bartuzi Z, Krogulska A. Anaphylaxis after consumption of pumpkin seeds in a 2-y-old child tolerant to its pulp: A case study. Nutrition 2021;89:111272. PubMed

See these in context on the Pumpkin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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