High Strength Garcinia Cambogia 750 mg Ingredients & Drug Interactions
What is this page for?
First and foremost: checking High Strength Garcinia Cambogia 750 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
High Strength Garcinia Cambogia 750 mg is a dietary supplement by Simply Supplements with 1 active ingredient. Its ingredients are commonly taken for weight loss, appetite suppression, curbing sugar and carb cravings.Based on those ingredients, 704 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Garcinia cambogia. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against High Strength Garcinia Cambogia 750 mg by Simply Supplements
Ask about any prescription or over-the-counter medication and we check it for interactions with High Strength Garcinia Cambogia 750 mg by Simply Supplements — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of High Strength Garcinia Cambogia 750 mg by Simply Supplements
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: garcinia cambogia at 750 mg per capsule. Garcinia's main compound is hydroxycitric acid (HCA), which is what's believed to be responsible for its effects.
The remaining ingredients are inactive: garcinia powder (part of the botanical), the capsule shell itself, and a color additive. These are excipients — they don't add active benefit, just help deliver the dose.
Does it work?
Not established
The evidence for garcinia cambogia isn't established in the data we hold. Our records show insufficient reliable evidence to rate it for athletic performance, fatty liver disease, high cholesterol, and obesity — the conditions it's often marketed for.
That doesn't mean it doesn't work; it means the studies we have aren't strong enough to say one way or the other.
How safe is it?
Well-documented data
Garcinia is generally well tolerated in short-term use, but there are rare reports worth knowing about. The most common side effects in studies are diarrhea, stomach discomfort, headache, and nausea — typically mild.
Rarely, garcinia has been linked with liver injury and liver failure; there are also isolated case reports of mania (especially in people with bipolar disorder, where it may trigger episodes), pancreatitis, and a severe heart inflammation. While these are uncommon, they're serious enough that caution is warranted.
Don't use this product during pregnancy or while breastfeeding — there isn't enough safety data to know whether it's okay.
Meds to double-check
Moderate interaction found
Before taking this product, check with your doctor or pharmacist if you're on any serotonergic drugs like antidepressants (especially SSRIs), blood thinners or antiplatelet drugs, diabetes medications, or any drug known to affect the liver. These are Moderate-severity interactions, and your provider needs to know you're considering garcinia so they can assess the risk for you individually.
The bottom line
Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.
Garcinia cambogia is generally tolerated for short periods, but it can interact with blood thinners, antidepressants, diabetes medications, and drugs that stress the liver. Rare but serious side effects including liver damage and mood changes have been reported.
If you're on any prescription medications or have liver, heart, or mood concerns, talk it over with your doctor or pharmacist before starting — they can review your specific situation and medications.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 24, 2017.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about High Strength Garcinia Cambogia 750 mg, straight from the product label.
| Brand | Simply Supplements |
|---|---|
| Barcode (UPC) | 5060370564194 |
| Net contents | 120 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Mar 24, 2017 |
| DSLD ID | 70655 |
| Product type | Botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other |
| Intended target group(s) | Vegetarian, Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for High Strength Garcinia Cambogia 750 mg by Simply Supplements, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Garcinia cambogia | 3000 mg | -- |
Other ingredients: Garcinia cambogia powder, Capsule Shell, Colour
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions
Food supplement: This product should not be used as a substitute for a varied diet.
Important information If you are taking any prescription medication, you have a medical condition or you have specific concerns about the suitability of our products, always consult your GP or Pharmacist prior to taking supplements.
Do not exceed stated dose.
Keep away from children at all times.
Do not use if seal is broken.
Pregnant or lactating women should consult a Doctor before using this product.
General Statements
EasyGest capsules Easy to swallow Easy to absorb Easy to digest No product odour No bad taste
Product information Garcinia Cambogia is a tropical fruit which has gained huge popularity for its potential weight loss benefits. It is thought that Garcinia Cambogia may help to promote satiety when taken before a meal.
Same day Despatch We will ensure your order is despatched on the day of receipt (when placed before 12.30pm) and that all orders placed after 12.30pm are despatched on the next working day. All sent 1st class!
PriceMatch guarantee! If you buy from us and then see the same product cheaper elsewhere we will refund the difference plus 10%!
Popular weight management support
Image is for illustration purposes only.
Seals/Symbols
V Vegetarian
Quality Assured
General
E580
Suggested/Recommended/Usage/Directions
Suggested daily intake: Take four capsules daily as a food supplement or as directed by a healthcare professional.
Storage
Store in a cool dry place.
Formulation
Suitable for Vegetarians.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
High Strength Garcinia Cambogia 750 mg by Simply Supplements label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in High Strength Garcinia Cambogia 750 mg by Simply Supplements
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size4 Capsule(s) Dosage formCapsule Amounts shown are per serving.
Garcinia cambogia
Interacts with704 drugs
Garcinia is a tropical fruit whose rind contains hydroxycitric acid (HCA), widely marketed for weight loss and appetite control. The scientific eviden...
Garcinia cambogia monograph & interactionsOther (inactive) ingredients: Garcinia cambogia powder, Capsule Shell, Colour. These complete the product’s ingredient list but are not active constituents.
High Strength Garcinia Cambogia 750 mg by Simply Supplements Drug Interactions
HelloPharmacist Interaction Report
High Strength Garcinia Cambogia by Simply Supplements contains garcinia cambogia, which has documented interactions with several medication types.
The most serious concern is with serotonergic drugs (antidepressants and similar medications) — there's a case report of a patient who developed serotonin syndrome after combining garcinia extract with escitalopram, a common antidepressant. This is a Moderate-severity risk.
Read the full breakdown — every affected drug type, severity by severity
Garcinia also interacts with blood thinners and antiplatelet drugs (like warfarin or aspirin) at Moderate severity; the active compound in garcinia may increase bleeding risk. It can have additive effects with diabetes medications and theoretically raise the risk of low blood sugar (hypoglycemia), and it may increase the risk of liver damage if taken alongside other drugs that stress the liver — both Moderate concerns.
Albeit there are no other active ingredients in this single-ingredient product, you'll want to run your exact medications through the search tool on this page before starting.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against High Strength Garcinia Cambogia 750 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in High Strength Garcinia Cambogia 750 mg interact with 704 drugs. Click any drug to see the details.
1 of the 1 ingredient in High Strength Garcinia Cambogia 750 mg interact with drugs. Each result below shows which ingredient is responsible. Garcinia cambogia
6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with High Strength Garcinia Cambogia 750 mg — through 1 ingredient. Tap an ingredient for the detail:
Garcinia CambogiaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia + 6-mercaptopurine interactionAbacavir Sulfate, Dolutegravir, LamivudineTriumeq
How Abacavir Sulfate, Dolutegravir, Lamivudine interacts with High Strength Garcinia Cambogia 750 mg — through 1 ingredient. Tap an ingredient for the detail:
Garcinia CambogiaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia + Abacavir Sulfate, Dolutegravir, Lamivudine interactionAbacavir, LamivudineEpzicom
How Abacavir, Lamivudine interacts with High Strength Garcinia Cambogia 750 mg — through 1 ingredient. Tap an ingredient for the detail:
Garcinia CambogiaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia + Abacavir, Lamivudine interactionAbciximabReoPro
How Abciximab interacts with High Strength Garcinia Cambogia 750 mg — through 1 ingredient. Tap an ingredient for the detail:
Garcinia CambogiaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hydroxycitric acid (HCA), the main active ingredient in garcinia, might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Garcinia Cambogia + Abciximab interactionAbiraterone
How Abiraterone interacts with High Strength Garcinia Cambogia 750 mg — through 1 ingredient. Tap an ingredient for the detail:
Garcinia CambogiaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with High Strength Garcinia Cambogia 750 mg — through 1 ingredient. Tap an ingredient for the detail:
Garcinia CambogiaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with High Strength Garcinia Cambogia 750 mg — through 1 ingredient. Tap an ingredient for the detail:
Garcinia CambogiaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hydroxycitric acid (HCA), the main active ingredient in garcinia, might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Garcinia Cambogia + Abrocitinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with High Strength Garcinia Cambogia 750 mg — through 1 ingredient. Tap an ingredient for the detail:
Garcinia CambogiaAntidiabetes Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, hydroxycitric acid (HCA), the main active ingredient in garcinia, might have additive effects with antidiabetes drugs and increase the risk of hypoglycemia.
Read the full Garcinia Cambogia + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with High Strength Garcinia Cambogia 750 mg — through 1 ingredient. Tap an ingredient for the detail:
Garcinia CambogiaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with High Strength Garcinia Cambogia 750 mg — through 1 ingredient. Tap an ingredient for the detail:
Garcinia CambogiaAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, hydroxycitric acid (HCA), the main active ingredient in garcinia, might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Garcinia Cambogia + Acenocoumarol interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with High Strength Garcinia Cambogia 750 mg — through 1 ingredient. Tap an ingredient for the detail:
Garcinia CambogiaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with High Strength Garcinia Cambogia 750 mg — through 1 ingredient. Tap an ingredient for the detail:
Garcinia CambogiaAnticoagulant/antiplatelet Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, hydroxycitric acid (HCA), the main active ingredient in garcinia, might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Garcinia Cambogia + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with High Strength Garcinia Cambogia 750 mg — through 1 ingredient. Tap an ingredient for the detail:
Garcinia CambogiaHepatotoxic Drugs, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with High Strength Garcinia Cambogia 750 mg — through 1 ingredient. Tap an ingredient for the detail:
Garcinia CambogiaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with High Strength Garcinia Cambogia 750 mg — through 1 ingredient. Tap an ingredient for the detail:
Garcinia CambogiaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with High Strength Garcinia Cambogia 750 mg — through 1 ingredient. Tap an ingredient for the detail:
Garcinia CambogiaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with High Strength Garcinia Cambogia 750 mg — through 1 ingredient. Tap an ingredient for the detail:
Garcinia CambogiaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with High Strength Garcinia Cambogia 750 mg — through 1 ingredient. Tap an ingredient for the detail:
Garcinia CambogiaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with High Strength Garcinia Cambogia 750 mg — through 1 ingredient. Tap an ingredient for the detail:
Garcinia CambogiaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with High Strength Garcinia Cambogia 750 mg — through 1 ingredient. Tap an ingredient for the detail:
Garcinia CambogiaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with High Strength Garcinia Cambogia 750 mg — through 1 ingredient. Tap an ingredient for the detail:
Garcinia CambogiaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with High Strength Garcinia Cambogia 750 mg — through 1 ingredient. Tap an ingredient for the detail:
Garcinia CambogiaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with High Strength Garcinia Cambogia 750 mg — through 1 ingredient. Tap an ingredient for the detail:
Garcinia CambogiaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with High Strength Garcinia Cambogia 750 mg — through 1 ingredient. Tap an ingredient for the detail:
Garcinia CambogiaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with High Strength Garcinia Cambogia 750 mg — through 1 ingredient. Tap an ingredient for the detail:
Garcinia CambogiaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with High Strength Garcinia Cambogia 750 mg — through 1 ingredient. Tap an ingredient for the detail:
Garcinia CambogiaHepatotoxic Drugs, Serotonergic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with High Strength Garcinia Cambogia 750 mg — through 1 ingredient. Tap an ingredient for the detail:
Garcinia CambogiaSerotonergic Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, combining garcinia with other serotonergic drugs might increase the risk of serotonergic side effects, including serotonin syndrome.
Read the full Garcinia Cambogia + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with High Strength Garcinia Cambogia 750 mg — through 1 ingredient. Tap an ingredient for the detail:
Garcinia CambogiaSerotonergic Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, combining garcinia with other serotonergic drugs might increase the risk of serotonergic side effects, including serotonin syndrome.
Read the full Garcinia Cambogia + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with High Strength Garcinia Cambogia 750 mg — through 1 ingredient. Tap an ingredient for the detail:
Garcinia CambogiaHepatotoxic Drugs, Serotonergic Drugs Moderate
Interaction Summary
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Garcinia Cambogia + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with High Strength Garcinia Cambogia 750 mg — through 1 ingredient. Tap an ingredient for the detail:
Garcinia CambogiaSerotonergic Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, combining garcinia with other serotonergic drugs might increase the risk of serotonergic side effects, including serotonin syndrome.
Read the full Garcinia Cambogia + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in High Strength Garcinia Cambogia 750 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Garcinia cambogia
Anticoagulant/Antiplatelet Drugs
Theoretically, hydroxycitric acid (HCA), the main active ingredient in garcinia, might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
HCA inhibits platelet aggregation in vitro. The inhibitory effect seems to be greater in platelets extracted from diabetic subjects than non-diabetic subjects.
Antidiabetes Drugs
Theoretically, hydroxycitric acid (HCA), the main active ingredient in garcinia, might have additive effects with antidiabetes drugs and increase the risk of hypoglycemia.
HCA reduces fasting and postprandial blood glucose levels in animal models, theoretically by delaying glucose absorption. This effect has not been reported in humans.
Hepatotoxic Drugs
Theoretically, concomitant use with other potentially hepatotoxic drugs might increase the risk of developing liver damage.
There have been reports of acute hepatitis with elevated liver enzymes associated with garcinia, when taken alone or in combination with other ingredients. Case reports collected from the Drug Induced Liver Injury Network suggest this risk may be greater in people who carry the HLA B*35:01 allele.
Serotonergic Drugs
Theoretically, combining garcinia with other serotonergic drugs might increase the risk of serotonergic side effects, including serotonin syndrome.
In one report, a patient experienced serotonin syndrome after taking garcinia extract (60% hydroxycitric acid) 1000 mg daily in combination with escitalopram 20 mg, which had been taken for a year. The patient was switched to sertraline 50 mg daily and again experienced serotonin syndrome.
Brand information
Manufacturer and brand details for High Strength Garcinia Cambogia 750 mg, from the product label.
Simply Supplements
See all Simply Supplements products- Name
- Simply Supplements
- Street Address
- PO Box 1330
- City
- Peterborough
- ZipCode
- PE2 2PW
- Phone Number
- 0800 988 0292
High Strength Garcinia Cambogia 750 mg by Simply Supplements: Common Questions
Does High Strength Garcinia Cambogia 750 mg by Simply Supplements interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take garcinia with my antidepressant?
Is garcinia safe to use while pregnant or breastfeeding?
What are the most common side effects?
Can garcinia help me lose weight or lower my cholesterol?
What's hydroxycitric acid, and why is it in garcinia?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if High Strength Garcinia Cambogia 750 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind High Strength Garcinia Cambogia 750 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
High Strength Garcinia Cambogia 750 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 44 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Garcinia 44 references
- Heymsfield SB, Allison DB, Vasselli JR, et al. Garcinia cambogia (hydroxycitric acid) as a potential antiobesity agent: a randomized controlled trial. JAMA 1998;280:1596-600. PubMed
- Soni MG, Burdock GA, Preuss HG, et al. Safety assessment of (-)-hydroxycitric acid and Super CitriMax, a novel calcium/potassium salt. Food Chem Toxicol 2004;42:1513-29. PubMed
- Stevens T, Qadri A, Zein NN. Two patients with acute liver injury associated with use of the herbal weight-loss supplement hydroxycut. Ann Intern Med 2005;142:477-8. PubMed
- Willis SL, Moawad FJ, Hartzell JD, et al. Hypertensive retinopathy associated with use of the ephedra-free weight-loss herbal supplement Hydroxycut. MedGenMed 2006;8:82.
- Preuss HG, Bagchi D, Bagchi M, et al. Effects of a natural extract of (-)-hydroxycitric acid (HCA-SX) and a combination of HCA-SX plus niacin-bound chromium and Gymnema sylvestre extract on weight loss. Diabetes Obes Metab 2004;6:171-180.
- Mansi IA, Huang J. Rhabdomyolysis in response to weight-loss herbal medicine. Am J Med Sci 2004;327:356-357. PubMed
- Lopez AM, Kornegay J, Hendrickson RG. Serotonin Toxicity Associated with Garcinia cambogia Over-the-counter Supplement. J Med Toxicol. 2014 Apr 4. [Epub ahead of print]. PubMed
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