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Dietary supplement

Horseradish Ingredients & Drug Interactions

by Hawaii Pharm

Horseradish label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Horseradish against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Horseradish is a dietary supplement by Hawaii Pharm with 1 active ingredient. Its ingredients are commonly taken for sinus and respiratory congestion, urinary tract infections, digestive support.Based on those ingredients, 16 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Horseradish Root Extract, Dry. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Horseradish by Hawaii Pharm

Ask about any prescription or over-the-counter medication and we check it for interactions with Horseradish by Hawaii Pharm — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Horseradish by Hawaii Pharm

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 6, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: horseradish root extract in dry form. Horseradish is a pungent root vegetable used traditionally to support respiratory and urinary health, though the evidence for these uses isn't well established.

The liquid also contains alcohol, water, and glycerin as inactive ingredients—these are the carriers and preservatives that keep the extract stable.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Horseradish product and its label doesn't state a use — see Horseradish's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for horseradish isn't yet solid. Our data shows insufficient reliable evidence to rate it for respiratory tract infections, intestinal parasites, urinary tract infections, or gout.

That doesn't mean it doesn't work—it means studies haven't firmly established whether it does. If you're considering it for any of these reasons, talk with your doctor about what the current research supports.

The evidence, ingredient by ingredient Horseradish

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Horseradish in food amounts is generally well tolerated. But this is a concentrated liquid supplement, and large amounts can irritate your digestive tract and mucous membranes.

The most common side effects from heavy use are gastrointestinal upset, diarrhea, and bloody vomiting. Rarely, consuming large amounts can cause vasovagal syncope (a sudden drop in heart rate and blood pressure leading to fainting).

During pregnancy, medicinal amounts of horseradish haven't been studied enough—the safety data advises against it. During breastfeeding, stick to food amounts; medicinal use hasn't been well studied.

Talk with your doctor or pharmacist before using this product if you're pregnant or nursing.

Side effects, ingredient by ingredient Horseradish

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Horseradish.
  • The most serious interaction on file is rated Moderate.
  • For scale: 16 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this horseradish supplement, double-check with your doctor or pharmacist if you're on thyroid hormone replacement therapy (such as levothyroxine or other thyroid medications). The extract may interfere with how these drugs work, and you may need dose monitoring or adjustment.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Horseradish supplement may help with certain respiratory or urinary concerns, but the evidence isn't firm yet. The main risk is if you take thyroid medication—horseradish could interfere with how it works.

If that's you, check with your doctor before starting. Otherwise, this product is generally well tolerated in normal amounts, though large doses can upset your stomach.

Have a conversation with your own healthcare provider about whether it fits your health picture.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jan 24, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Horseradish, straight from the product label.

Brand Hawaii Pharm
Barcode (UPC) 840253627858
Net contents 4 Fluid Ounce(s); 120 mL
Market status On market
Date entered into DSLD Jan 24, 2024
DSLD ID 301683
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Horseradish by Hawaii Pharm, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.7 mL
Maximum serving Sizes:
1 mL
Servings per container
120
UPC/BARCODE
840253627858
IngredientAmount% DV
Horseradish Root Extract, Dry983 mg--

Other ingredients: Alcohol, Water, Glycerin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

Hawaii Pharm Herbal Extract Highest quality since 2008

Suggested/Recommended/Usage/Directions

Suggested use: Shake well before using. For adults add about 20-30 drops (0.7-1 mL, one full squeeze of the dropper bulb) to some juice or water, up to 4 times a day.

Precautions

Warning: We recommend to seek expert medical advice before taking.

Do not use if you are allergic to any ingredients.

Consult your physician before giving to children under 18, during pregnancy, if nursing or taking medications.

Consult your physician before giving to children under 18, during pregnancy, if nursing or taking medications.

May affect the ability to drive and operate machinery. May have contraindications, can cause side effects and adverse reactions. Do not use if seal is broken or missing.

Keep out of the reach of children!

Storage

Store in a cool dry place.

Seals/Symbols

cGMP Made in compliance with cGMP 21 CFR 111 in an FDA registered and inspected facility.

Organic Alcohol Based USA Made in United States of America

FDA Disclaimer Statement

This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure or prevent any disease.

General Statements

Scan this QR-code to get 15% discount on your next purchase. Limited time deal.

Formula

Cochlearia armoracia

Organic Alcohol Based

Formulation

Only natural ingredients Purity is laboratory tested and verified

All the raw materials are gluten-free by their nature No artificial colors, flavors, or preservatives

Not tested on animals

Organic Alcohol Based

Made in USA, Hawaii

FDA Statement of Identity

Herbal Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Horseradish by Hawaii Pharm label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Horseradish label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Horseradish by Hawaii Pharm

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.7 mL Dosage formLiquid Servings per container120 Amounts shown are per serving.

Horseradish Root Extract, Dry

Interacts with
16 drugs
983 mg per serving Form: Cochlearia armoracia Root Extract, Dry

Horseradish is a pungent root used as a food and folk remedy, most often for sinus congestion and urinary tract complaints. Human evidence is limited,...

Horseradish Root Extract, Dry monograph & interactions

Other (inactive) ingredients: Alcohol, Water, Glycerin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Horseradish by Hawaii Pharm Drug Interactions

Want to check YOUR meds against Horseradish?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
16Drugs
16 Moderate

Ingredients driving the most interactions

Horseradish Root Extract, Dry 16

Individual Drug Interactions

The ingredients in Horseradish interact with 16 drugs. Click any drug to see the details.

1 of the 1 ingredient in Horseradish interact with drugs. Each result below shows which ingredient is responsible. Horseradish Root Extract, Dry

Each ingredient & the kinds of drugs it affects

For each ingredient in Horseradish with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Horseradish Root Extract, Dry1 drug type · 16 drugs

Thyroid Hormone

Theoretically, horseradish might interfere with the effects of thyroid hormone.
Horseradish and other members of the cabbage and mustard family are associated with depressed thyroid function.

Likelihood Possible Evidence D
Horseradish Root Extract, Dry full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Horseradish, from the product label.

Hawaii Pharm

See all Hawaii Pharm products
Name
Hawaii Pharm LLC
Street Address
510 Sumner St. Ste. 613
City
Honolulu
State
HI
ZipCode
96817
Phone Number
888-854-2924
Web Address
www.hawaiipharm.com
Pharmacist Counseling Corner

Horseradish by Hawaii Pharm: Common Questions

Does Horseradish by Hawaii Pharm interact with any medications?
Yes. Based on its ingredients, Horseradish has a known interaction with 16 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Horseradish contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will horseradish help me avoid catching a cold or respiratory infection?
Horseradish is traditionally used for respiratory health, but we don't have strong enough evidence yet to say whether it actually works for that. The research just isn't there. Your doctor can discuss other, better-studied options with you.
What happens if I take too much of this liquid?
Large amounts can irritate your stomach and digestive tract, causing upset, diarrhea, or even bloody vomiting. In rare cases, consuming a lot at once can cause a sudden fainting spell. Stick to the dose on the label and don't exceed it.
Is it safe to use this while pregnant?
No. Medicinal amounts of horseradish during pregnancy haven't been studied enough to know whether it's safe, so the data advises against it. Talk with your doctor about what you can safely take instead.
Can I use this if I'm breastfeeding?
Food amounts of horseradish are likely safe while breastfeeding, but medicinal use—like this concentrated supplement—hasn't been well studied. To be safe, ask your doctor or pharmacist whether this product is okay for you right now.
What's in this liquid besides the horseradish?
The liquid also contains alcohol, glycerin, and water. These are inactive ingredients that preserve and carry the horseradish extract.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Horseradish is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Horseradish label
Go deeper

The Full Monographs Behind Horseradish’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Horseradish

Interacts with 16 drugs

Horseradish is a pungent root used as a food and folk remedy, most often for sinus congestion and urinary tract complaints. Human evidence is limited, and while culinary amounts are generall...

Read the full Horseradish monograph →
Sources

Sources & How We Checked

Horseradish's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Horseradish 6 references
  1. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
  2. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  3. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  4. Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
  5. Panter, K. E. and James, L. F. Natural plant toxicants in milk: a review. J Anim Sci 1990;68(3):892-904. PubMed
  6. Lehmann CU, Puckett AL, Betz BO. 56-year-old man - increased heart rate - weakness - intense sweating - horseradish consumption - Dx?. J Fam Pract 2022;71(7):317-321. PubMed

See these in context on the Horseradish monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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