Huperzine-A 50 mcg Ingredients & Drug Interactions
by SuperSmart
What is this page for?
First and foremost: checking Huperzine-A 50 mcg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Huperzine-A 50 mcg is a dietary supplement by SuperSmart with 1 active ingredient. Its ingredients are commonly taken for memory and cognitive support, alzheimer's disease and dementia, general brain or 'nootropic' support.Based on those ingredients, 219 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Huperzia serrata extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Huperzine-A 50 mcg by SuperSmart
Ask about any prescription or over-the-counter medication and we check it for interactions with Huperzine-A 50 mcg by SuperSmart — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Huperzine-A 50 mcg by SuperSmart
Four independent checks of what is known — a summary of the available information, not a grade of the product itself.
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
The stated purpose hasn't been mapped to our evidence data yet.
Why this rating?
- We haven't mapped this product's purpose to our evidence data yet — it'll be graded on the next content refresh.
Every active ingredient lists its own amount on the label.
Why this rating?
- The label discloses an exact amount for 1 of its 1 active ingredient.
- No proprietary blends here — you can verify the dose of every single component.
The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.
Why this rating?
- 1 of the 1 matched ingredient can interact with medications — Toothed Clubmoss.
- The most serious interaction on file is rated Moderate.
- For scale: 219 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.
Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.
Why this rating?
- We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
- Pregnancy & breastfeeding safety ratings cover 1 of 1.
- General safety write-ups exist for 1 of 1.
- Remember: this measures how much safety information exists. Thin data is not the same as being safe.
HelloPharmacist summaryFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 24, 2020.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Huperzine-A 50 mcg, straight from the product label.
| Brand | SuperSmart |
|---|---|
| Net contents | 120 Vegetarian Capsule(s) |
| Market status | Off market |
| Date entered into DSLD | Jun 24, 2020 |
| DSLD ID | 222878 |
| Product type | Botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Huperzine-A 50 mcg by SuperSmart, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Huperzia serrata extract | 10 mg | -- |
Other ingredients: Acacia Gum, Rice Bran
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity
Brain Supplement
Suggested/Recommended/Usage/Directions
Recommended Use: Adults. Take one vegetarian capsule morning and evening.
Formula
Each vegetarian capsule contains 50 mcg of Huperzia serrata extract standardised to 1% Huperzine-A.
Precautions
Precautions: Do not exceed the recommended daily dose. This product is a nutritional supplement and should not replace a varied, balanced diet.
Keep out of childrens' reach.
As with any nutritional supplement, you should consult a health professional before taking this product if you are pregnant, breastfeeding or have a health problem.
Storage
Store away from direct light, heat and humidity.
General Statements
RDA not established
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Huperzine-A 50 mcg by SuperSmart label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Huperzine-A 50 mcg by SuperSmart
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Vegetarian Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.
Huperzia serrata extract
Interacts with219 drugs
Toothed Clubmoss is a moss-like plant best known as the natural source of huperzine A, a compound studied mainly for memory and Alzheimer's disease. S...
Huperzia serrata extract monograph & interactionsOther (inactive) ingredients: Acacia Gum, Rice Bran. These complete the product’s ingredient list but are not active constituents.
Huperzine-A 50 mcg by SuperSmart Drug Interactions
Huperzine-A 50 mcg contains a single active ingredient, and it has known interactions with 219 medications. Here’s the picture, then you can look up your own drug.
Want to check YOUR meds against Huperzine-A 50 mcg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Huperzine-A 50 mcg interact with 219 drugs. Click any drug to see the details.
1 of the 1 ingredient in Huperzine-A 50 mcg interact with drugs. Each result below shows which ingredient is responsible. Huperzia serrata extract
AcepromazineAtravet
How Acepromazine interacts with Huperzine-A 50 mcg — through 1 ingredient. Tap an ingredient for the detail:
Huperzia Serrata ExtractAnticholinergic Drugs Moderate
Interaction Summary
In animal models, toothed clubmoss and huperzine A, an active constituent of toothed clubmoss, reversed cognitive deficits induced by scopolamine.
Read the full Huperzia Serrata Extract + Acepromazine interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Huperzine-A 50 mcg — through 1 ingredient. Tap an ingredient for the detail:
Huperzia Serrata ExtractAnticholinergic Drugs Moderate
Interaction Summary
In animal models, toothed clubmoss and huperzine A, an active constituent of toothed clubmoss, reversed cognitive deficits induced by scopolamine.
Read the full Huperzia Serrata Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Huperzine-A 50 mcg — through 1 ingredient. Tap an ingredient for the detail:
Huperzia Serrata ExtractAnticholinergic Drugs Moderate
Interaction Summary
In animal models, toothed clubmoss and huperzine A, an active constituent of toothed clubmoss, reversed cognitive deficits induced by scopolamine.
Read the full Huperzia Serrata Extract + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Huperzine-A 50 mcg — through 1 ingredient. Tap an ingredient for the detail:
Huperzia Serrata ExtractAnticholinergic Drugs Moderate
Interaction Summary
In animal models, toothed clubmoss and huperzine A, an active constituent of toothed clubmoss, reversed cognitive deficits induced by scopolamine.
Read the full Huperzia Serrata Extract + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Huperzine-A 50 mcg — through 1 ingredient. Tap an ingredient for the detail:
Huperzia Serrata ExtractAnticholinergic Drugs Moderate
Interaction Summary
In animal models, toothed clubmoss and huperzine A, an active constituent of toothed clubmoss, reversed cognitive deficits induced by scopolamine.
Read the full Huperzia Serrata Extract + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Huperzine-A 50 mcg — through 1 ingredient. Tap an ingredient for the detail:
Huperzia Serrata ExtractAnticholinergic Drugs Moderate
Interaction Summary
In animal models, toothed clubmoss and huperzine A, an active constituent of toothed clubmoss, reversed cognitive deficits induced by scopolamine.
Read the full Huperzia Serrata Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Huperzine-A 50 mcg — through 1 ingredient. Tap an ingredient for the detail:
Huperzia Serrata ExtractAnticholinergic Drugs Moderate
Interaction Summary
In animal models, toothed clubmoss and huperzine A, an active constituent of toothed clubmoss, reversed cognitive deficits induced by scopolamine.
Read the full Huperzia Serrata Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Huperzine-A 50 mcg — through 1 ingredient. Tap an ingredient for the detail:
Huperzia Serrata ExtractAnticholinergic Drugs Moderate
Interaction Summary
In animal models, toothed clubmoss and huperzine A, an active constituent of toothed clubmoss, reversed cognitive deficits induced by scopolamine.
Read the full Huperzia Serrata Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with Huperzine-A 50 mcg — through 1 ingredient. Tap an ingredient for the detail:
Huperzia Serrata ExtractAnticholinergic Drugs Moderate
Interaction Summary
In animal models, toothed clubmoss and huperzine A, an active constituent of toothed clubmoss, reversed cognitive deficits induced by scopolamine.
Read the full Huperzia Serrata Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, SalicylamideRhinogesic GG
How Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interacts with Huperzine-A 50 mcg — through 1 ingredient. Tap an ingredient for the detail:
Huperzia Serrata ExtractAnticholinergic Drugs Moderate
Interaction Summary
In animal models, toothed clubmoss and huperzine A, an active constituent of toothed clubmoss, reversed cognitive deficits induced by scopolamine.
Read the full Huperzia Serrata Extract + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylephrineAlka-Seltzer PLUS, Histex SR, Protid
How Acetaminophen, Chlorpheniramine, Phenylephrine interacts with Huperzine-A 50 mcg — through 1 ingredient. Tap an ingredient for the detail:
Huperzia Serrata ExtractAnticholinergic Drugs Moderate
Interaction Summary
In animal models, toothed clubmoss and huperzine A, an active constituent of toothed clubmoss, reversed cognitive deficits induced by scopolamine.
Read the full Huperzia Serrata Extract + Acetaminophen, Chlorpheniramine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, Phenylephrine, SalicylamideRhinogesic, Rhinogesic JR
How Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interacts with Huperzine-A 50 mcg — through 1 ingredient. Tap an ingredient for the detail:
Huperzia Serrata ExtractAnticholinergic Drugs Moderate
Interaction Summary
In animal models, toothed clubmoss and huperzine A, an active constituent of toothed clubmoss, reversed cognitive deficits induced by scopolamine.
Read the full Huperzia Serrata Extract + Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylpropanolamineAlumadrine, Conex, Sinadrin Max Strength, Sinulin
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine interacts with Huperzine-A 50 mcg — through 1 ingredient. Tap an ingredient for the detail:
Huperzia Serrata ExtractAnticholinergic Drugs Moderate
Interaction Summary
In animal models, toothed clubmoss and huperzine A, an active constituent of toothed clubmoss, reversed cognitive deficits induced by scopolamine.
Read the full Huperzia Serrata Extract + Acetaminophen, Chlorpheniramine, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, OpiumHista-Derfule
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interacts with Huperzine-A 50 mcg — through 1 ingredient. Tap an ingredient for the detail:
Huperzia Serrata ExtractAnticholinergic Drugs Moderate
Interaction Summary
In animal models, toothed clubmoss and huperzine A, an active constituent of toothed clubmoss, reversed cognitive deficits induced by scopolamine.
Read the full Huperzia Serrata Extract + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, PhenyltoloxamineNorel Plus
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interacts with Huperzine-A 50 mcg — through 1 ingredient. Tap an ingredient for the detail:
Huperzia Serrata ExtractAnticholinergic Drugs Moderate
Interaction Summary
In animal models, toothed clubmoss and huperzine A, an active constituent of toothed clubmoss, reversed cognitive deficits induced by scopolamine.
Read the full Huperzia Serrata Extract + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interactionAcetaminophen, Chlorpheniramine, PseudoephedrineAlka-Seltzer PLUS Liquid Gels, Children's Tylenol Cold, Codimal, Comtrex, Extra Strength Tylenol Allergy Sinus, Lorsin +3 more
How Acetaminophen, Chlorpheniramine, Pseudoephedrine interacts with Huperzine-A 50 mcg — through 1 ingredient. Tap an ingredient for the detail:
Huperzia Serrata ExtractAnticholinergic Drugs Moderate
Interaction Summary
In animal models, toothed clubmoss and huperzine A, an active constituent of toothed clubmoss, reversed cognitive deficits induced by scopolamine.
Read the full Huperzia Serrata Extract + Acetaminophen, Chlorpheniramine, Pseudoephedrine interactionAcetaminophen, Codeine, DoxylamineMersyndol
How Acetaminophen, Codeine, Doxylamine interacts with Huperzine-A 50 mcg — through 1 ingredient. Tap an ingredient for the detail:
Huperzia Serrata ExtractAnticholinergic Drugs Moderate
Interaction Summary
In animal models, toothed clubmoss and huperzine A, an active constituent of toothed clubmoss, reversed cognitive deficits induced by scopolamine.
Read the full Huperzia Serrata Extract + Acetaminophen, Codeine, Doxylamine interactionAcetaminophen, Dextromethorphan, Doxylamine, PseudoephedrineVicks NyQuil
How Acetaminophen, Dextromethorphan, Doxylamine, Pseudoephedrine interacts with Huperzine-A 50 mcg — through 1 ingredient. Tap an ingredient for the detail:
Huperzia Serrata ExtractAnticholinergic Drugs Moderate
Interaction Summary
In animal models, toothed clubmoss and huperzine A, an active constituent of toothed clubmoss, reversed cognitive deficits induced by scopolamine.
Read the full Huperzia Serrata Extract + Acetaminophen, Dextromethorphan, Doxylamine, Pseudoephedrine interactionAcetaminophen, Dextromethorphan, Phenylpropanolamine, PyrilamineTheracaps
How Acetaminophen, Dextromethorphan, Phenylpropanolamine, Pyrilamine interacts with Huperzine-A 50 mcg — through 1 ingredient. Tap an ingredient for the detail:
Huperzia Serrata ExtractAnticholinergic Drugs Moderate
Interaction Summary
In animal models, toothed clubmoss and huperzine A, an active constituent of toothed clubmoss, reversed cognitive deficits induced by scopolamine.
Read the full Huperzia Serrata Extract + Acetaminophen, Dextromethorphan, Phenylpropanolamine, Pyrilamine interactionAcetaminophen, DiphenhydramineTylenol PM, Tylenol PM Ex Strength
How Acetaminophen, Diphenhydramine interacts with Huperzine-A 50 mcg — through 1 ingredient. Tap an ingredient for the detail:
Huperzia Serrata ExtractAnticholinergic Drugs Moderate
Interaction Summary
In animal models, toothed clubmoss and huperzine A, an active constituent of toothed clubmoss, reversed cognitive deficits induced by scopolamine.
Read the full Huperzia Serrata Extract + Acetaminophen, Diphenhydramine interactionAcetaminophen, Diphenhydramine, PseudoephedrineChildren's Tylenol Allergy, Cold Control, Contac Night Allergy Relief
How Acetaminophen, Diphenhydramine, Pseudoephedrine interacts with Huperzine-A 50 mcg — through 1 ingredient. Tap an ingredient for the detail:
Huperzia Serrata ExtractAnticholinergic Drugs Moderate
Interaction Summary
In animal models, toothed clubmoss and huperzine A, an active constituent of toothed clubmoss, reversed cognitive deficits induced by scopolamine.
Read the full Huperzia Serrata Extract + Acetaminophen, Diphenhydramine, Pseudoephedrine interactionAcetaminophen, Doxylamine, PseudoephedrineEx Strength Tylenol Sinus Nighttime
How Acetaminophen, Doxylamine, Pseudoephedrine interacts with Huperzine-A 50 mcg — through 1 ingredient. Tap an ingredient for the detail:
Huperzia Serrata ExtractAnticholinergic Drugs Moderate
Interaction Summary
In animal models, toothed clubmoss and huperzine A, an active constituent of toothed clubmoss, reversed cognitive deficits induced by scopolamine.
Read the full Huperzia Serrata Extract + Acetaminophen, Doxylamine, Pseudoephedrine interactionAcetaminophen, Pamabrom, PyrilamineMidol Max Strength PMS, Pamprin, Pamprin ES
How Acetaminophen, Pamabrom, Pyrilamine interacts with Huperzine-A 50 mcg — through 1 ingredient. Tap an ingredient for the detail:
Huperzia Serrata ExtractAnticholinergic Drugs Moderate
Interaction Summary
In animal models, toothed clubmoss and huperzine A, an active constituent of toothed clubmoss, reversed cognitive deficits induced by scopolamine.
Read the full Huperzia Serrata Extract + Acetaminophen, Pamabrom, Pyrilamine interactionAcetaminophen, Phenylephrine, ChlorpheniramineSuper Cold Tabs
How Acetaminophen, Phenylephrine, Chlorpheniramine interacts with Huperzine-A 50 mcg — through 1 ingredient. Tap an ingredient for the detail:
Huperzia Serrata ExtractAnticholinergic Drugs Moderate
Interaction Summary
In animal models, toothed clubmoss and huperzine A, an active constituent of toothed clubmoss, reversed cognitive deficits induced by scopolamine.
Read the full Huperzia Serrata Extract + Acetaminophen, Phenylephrine, Chlorpheniramine interactionAcetylcholineMiochol-E
How Acetylcholine interacts with Huperzine-A 50 mcg — through 1 ingredient. Tap an ingredient for the detail:
Huperzia Serrata ExtractCholinergic Drugs Moderate
Interaction Summary
Huperzine A, a constituent of toothed clubmoss, has demonstrated acetylcholinesterase inhibitory properties.
Read the full Huperzia Serrata Extract + Acetylcholine interactionAclidinium BromideTudorza Pressair
How Aclidinium Bromide interacts with Huperzine-A 50 mcg — through 1 ingredient. Tap an ingredient for the detail:
Huperzia Serrata ExtractAnticholinergic Drugs Moderate
Interaction Summary
In animal models, toothed clubmoss and huperzine A, an active constituent of toothed clubmoss, reversed cognitive deficits induced by scopolamine.
Read the full Huperzia Serrata Extract + Aclidinium Bromide interactionAclidinium Bromide, Formoterol Fumarate DihydrateDuaklir Pressair
How Aclidinium Bromide, Formoterol Fumarate Dihydrate interacts with Huperzine-A 50 mcg — through 1 ingredient. Tap an ingredient for the detail:
Huperzia Serrata ExtractAnticholinergic Drugs Moderate
Interaction Summary
In animal models, toothed clubmoss and huperzine A, an active constituent of toothed clubmoss, reversed cognitive deficits induced by scopolamine.
Read the full Huperzia Serrata Extract + Aclidinium Bromide, Formoterol Fumarate Dihydrate interactionAerosphere Budesonide, Formoterol Fumarate, GlycopyrrolateBreztri
How Aerosphere Budesonide, Formoterol Fumarate, Glycopyrrolate interacts with Huperzine-A 50 mcg — through 1 ingredient. Tap an ingredient for the detail:
Huperzia Serrata ExtractAnticholinergic Drugs Moderate
Interaction Summary
In animal models, toothed clubmoss and huperzine A, an active constituent of toothed clubmoss, reversed cognitive deficits induced by scopolamine.
Read the full Huperzia Serrata Extract + Aerosphere Budesonide, Formoterol Fumarate, Glycopyrrolate interactionAmantadineGocovri, Osmolex ER, Symmetrel
How Amantadine interacts with Huperzine-A 50 mcg — through 1 ingredient. Tap an ingredient for the detail:
Huperzia Serrata ExtractAnticholinergic Drugs Moderate
Interaction Summary
In animal models, toothed clubmoss and huperzine A, an active constituent of toothed clubmoss, reversed cognitive deficits induced by scopolamine.
Read the full Huperzia Serrata Extract + Amantadine interactionAmbenonium ChlorideMytelase
How Ambenonium Chloride interacts with Huperzine-A 50 mcg — through 1 ingredient. Tap an ingredient for the detail:
Huperzia Serrata ExtractCholinergic Drugs Moderate
Interaction Summary
Huperzine A, a constituent of toothed clubmoss, has demonstrated acetylcholinesterase inhibitory properties.
Read the full Huperzia Serrata Extract + Ambenonium Chloride interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Huperzine-A 50 mcg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Huperzia serrata extract
Anticholinergic Drugs
In animal models, toothed clubmoss and huperzine A, an active constituent of toothed clubmoss, reversed cognitive deficits induced by scopolamine. Theoretically, concurrent use of anticholinergic drugs and toothed clubmoss might decrease the effectiveness of toothed clubmoss or the anticholinergic drug.
Some anticholinergic drugs include atropine, benztropine (Cogentin), biperiden (Akineton), procyclidine (Kemadrin), and trihexyphenidyl (Artane).
Cholinergic Drugs
Huperzine A, a constituent of toothed clubmoss, has demonstrated acetylcholinesterase inhibitory properties. Theoretically, concurrent use of toothed clubmoss with cholinergic drugs might have additive effects and increase the risk of cholinergic side effects.
Cholinergic drugs include bethanechol (Urecholine), donepezil (Aricept), echothiophate (Phospholine Iodide), edrophonium (Enlon, Reversol, Tensilon), neostigmine (Prostigmin), physostigmine (Antilirium), pyridostigmine (Mestinon, Regonol), succinylcholine (Anectine, Quelicin), and tacrine (Cognex).
Brand information
Manufacturer and brand details for Huperzine-A 50 mcg, from the product label.
SuperSmart
See all SuperSmart products- Name
- Smart Nutrition S.A.
- Street Address
- 18 Rue de l'Eau
- City
- Luxembourg
- ZipCode
- L-1449
Huperzine-A 50 mcg by SuperSmart: Common Questions
Does Huperzine-A 50 mcg by SuperSmart interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Huperzine-A 50 mcg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Huperzine-A 50 mcg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Huperzine-A 50 mcg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 3 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Toothed Clubmoss 3 references
- Budavari S, ed. The Merck Index. 12th ed. Whitehouse Station, NJ: Merck & Co., Inc., 1996.
- Zhang RW, Tang XC, Han YY, et al. [Drug evaluation of huperzine A in the treatment of senile memory disorders]. Chung Kuo Yao Li Hsueh Pao 1991;12:250-2.
- Ohba T, Yoshino Y, Ishisaka M, et al. Japanese Huperzia serrata extract and the constituent, huperzine A, ameliorate the scopolamine-induced cognitive impairment in mice. Biosci Biotechnol Biochem. 2015;79(11):1838-44.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC