Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Hype Extreme Cotton Candy Ingredients & Drug Interactions

by Blackstone Labs

Hype Extreme Cotton Candy label
See full label image
Powder Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Hype Extreme Cotton Candy against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Hype Extreme Cotton Candy is a dietary supplement by Blackstone Labs with 5 active ingredients. Its ingredients are commonly taken for memory and learning support, age-related cognitive decline, alzheimer's disease and dementia (under study).Based on those ingredients, 1,375 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Rhodiola rosea, Huperzine A, Sodium Nitrate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Hype Extreme Cotton Candy by Blackstone Labs

Ask about any prescription or over-the-counter medication and we check it for interactions with Hype Extreme Cotton Candy by Blackstone Labs — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Hype Extreme Cotton Candy by Blackstone Labs

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 6, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 5 of its 5 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Hype Extreme Cotton Candy contains five active ingredients. Alpha-GPC is a compound that supports brain function and is studied for memory and cognitive health.

Huperzine A is an alkaloid that works by slowing the breakdown of acetylcholine, a neurotransmitter involved in thinking and memory. Sodium nitrate is an electrolyte (salt) added for hydration support.

Glycerol powder is a humectant and osmotic agent that can draw water into the intestines and is used for athletic performance and occasional constipation relief. Rhodiola rosea is an adaptogenic plant extract that may help with fatigue and stress response.

The product also contains inactive ingredients—silicon dioxide and natural and artificial flavors—which serve as flow agents and flavoring.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: increase nitric oxide production and workout performance.
  • We looked for evidence on: Athletic performance, Cognitive function, Memory, Fatigue, Stress, Endurance — and 2 related terms.
  • The strongest evidence on file: Glycerol is rated "Possibly Effective" for Athletic performance (Natural Medicines).
  • Also on file: Huperzine A is rated "Insufficient Reliable Evidence To Rate" for Athletic performance, Memory.
  • Also on file: Rhodiola is rated "Insufficient Reliable Evidence To Rate" for Athletic performance, Chronic fatigue syndrome (CFS), Fatigue, Stress.

Alpha-GPC is possibly effective for Alzheimer disease; evidence for brain tumor, cognitive function, vascular dementia, and stroke is insufficient. Huperzine A is possibly effective for Alzheimer disease; evidence for athletic performance, cognitive impairment, vascular dementia, depression, and memory is insufficient.

Sodium nitrate is likely effective for cystic fibrosis and possibly effective for amphotericin B nephrotoxicity; evidence for bipolar disorder and congestive heart failure is insufficient. Glycerol is likely effective for constipation and possibly effective for ichthyosis and athletic performance.

Rhodiola rosea's evidence is insufficient for altitude sickness, generalized anxiety, arrhythmia, athletic performance, and bladder cancer. Overall, the evidence base for most of these ingredients' intended uses is limited.

The evidence, ingredient by ingredient Alpha-gpc Huperzine A Sodium Glycerol Rhodiola

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 5 of the 5 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 5 of 5.
  • General safety write-ups exist for 5 of 5.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Alpha-GPC is generally well tolerated but long-term safety is not fully established; it's rarely associated with dizziness, headache, insomnia, and in very rare cases stroke, especially with use for 2 months or longer. Huperzine A is pharmacologically active and can cause dose-dependent cholinergic side effects like blurred vision, dizziness, dry mouth, nausea, vomiting, and diarrhea; the data advises against it in pregnancy and while breastfeeding.

Sodium nitrate, when taken in excess, is linked to high blood pressure and heart strain; normal dietary amounts are fine, but avoid supplemental sodium or very high intake without medical advice. Glycerol is generally well tolerated in normal amounts but large doses can cause bloating, nausea, vomiting, diarrhea, dizziness, and headache.

Rhodiola is generally well tolerated for short-term use but long-term safety is not well studied; the data advises against it in pregnancy and while breastfeeding. For pregnancy and breastfeeding safety specific to this product, talk with your doctor or pharmacist.

Side effects, ingredient by ingredient Alpha-gpc Huperzine A Sodium Glycerol Rhodiola

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 4 of the 5 matched ingredients can interact with medications — Huperzine A, Rhodiola, Alpha-gpc, Sodium.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: immunosuppressants / transplant drugs; diabetes medications; lithium.
  • For scale: 1,376 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Hype Extreme Cotton Candy, double-check with your doctor or pharmacist if you take blood pressure medications (antihypertensives), cholinergic drugs, antidiabetes drugs, lithium, corticosteroids, or any medication metabolized by your liver (CYP2C9, CYP1A2, or CYP3A4 substrates). The sodium content alone can reduce how well blood pressure drugs work and dangerously raise lithium levels.

Huperzine A's cholinergic effects may interact with or enhance certain medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This is a pre-workout powder aimed at boosting mental clarity and athletic performance through cholinergic and adaptogenic ingredients. It's not for you if you take blood pressure medications, medications that boost acetylcholine (such as certain Alzheimer drugs), lithium, antidiabetes drugs, or any drug metabolized by your liver—the interaction risks are real.

If you're pregnant, breastfeeding, or take any prescription medication at all, check with your doctor or pharmacist before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 5 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 24, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Hype Extreme Cotton Candy, straight from the product label.

Brand Blackstone Labs
Barcode (UPC) 638932685325
Net contents 7.05 Oz(s); 200 Gram(s)
Market status On market
Date entered into DSLD Jul 24, 2019
DSLD ID 204971
Product type Other Combinations
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Hype Extreme Cotton Candy by Blackstone Labs, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
8 Gram(s)
Maximum serving Sizes:
8 Gram(s)
Servings per container
25
UPC/BARCODE
638932685325
IngredientAmount% DV
Alpha GPC250 mg--
Huperzine A300 mcg--
Sodium Nitrate1.5 Gram(s)--
Glycerol powder2 Gram(s)--
Rhodiola rosea300 mg--

Other ingredients: Silicon Dioxide, Natural and Artificial flavors

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Stimulant free

General Statements

Dramatically increases N.O. Production & vascularity Enhances mood & focus Extreme cell Volumizing effects

25 servings Naturally and artificially flavored

The Guerrilla Chemist

Suggested/Recommended/Usage/Directions

Directions As a dietary supplement, take 1 scoop mixed with 8 oz of water, 30 minutes before a workout. Do not exceed 1 scoop per 24 hour period.

Precautions

Do not exceed 1 scoop per 24 hour period.

Warning This product is intended to be consumed by healthy adults 18 years of age or older.

This product should only be used under medical or dietetic supervision. This product is not intended as a sole source of nutrition and should be consumed in conjunction with an appropriate physical training or exercise program.

Do not take this product of you are pregnant or nursing.

Do not take this product if you have any current or pre-existing medical conditions.

Do not take this product if you currently taking any prescription or over-the-counter medications intended to promote vasodilation and/or erectile dysfunction. In particular, do not take if you take other nitrate-containing medications, as this can cause an unsafe drop in blood pressure.

Do not consume more that one serving per day.

Keep out of reach of children.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent disease.

Formula

Revolutionary Nitric Oxide & Pump Formula

HydroMax Glycerol powder 65%

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Hype Extreme Cotton Candy by Blackstone Labs label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Hype Extreme Cotton Candy label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Hype Extreme Cotton Candy by Blackstone Labs

These are the 5 active ingredients this product is made of. Select any to open its full monograph.

Serving size8 Gram(s) Dosage formPowder Servings per container25 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Alpha GPC

Interacts with
16 drugs
250 mg per serving

Alpha-GPC is a choline-containing compound used mainly for memory, brain health, and as a choline source. There is some evidence it may help cognition...

Alpha GPC monograph & interactions

Huperzine A

Interacts with
219 drugs
300 mcg per serving Form: Huperzia serrata

Huperzine A is a purified compound from a Chinese clubmoss that acts like a mild cholinesterase inhibitor, similar in mechanism to some prescription A...

Huperzine A monograph & interactions

Sodium Nitrate

Interacts with
205 drugs
1.5 Gram(s) per serving

Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets g...

Sodium Nitrate monograph & interactions

Glycerol powder

No known
interactions
2 Gram(s) per serving Form: HydroMax

Glycerol (glycerin) is a sweet, syrupy compound made naturally in the body and widely used in foods, skin products, and medicines. It is well establis...

Glycerol powder monograph & interactions

Rhodiola rosea

Interacts with
1,271 drugs
300 mg per serving Form: Salidrosides

Rhodiola is an herb traditionally used to fight fatigue and help the body cope with stress. Some small studies suggest it may modestly reduce fatigue...

Rhodiola rosea monograph & interactions

Other (inactive) ingredients: Silicon Dioxide, Natural and Artificial flavors. These complete the product’s ingredient list but are not active constituents.

Interaction report

Hype Extreme Cotton Candy by Blackstone Labs Drug Interactions

Want to check YOUR meds against Hype Extreme Cotton Candy?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1,375Drugs
844 Moderate 531 Minor

Ingredients driving the most interactions

Rhodiola rosea 1,271
Huperzine A 219
Sodium Nitrate 205
Alpha GPC 16

Individual Drug Interactions

The ingredients in Hype Extreme Cotton Candy interact with 1,375 drugs. Click any drug to see the details.

4 of the 5 ingredients in Hype Extreme Cotton Candy interact with drugs. Each result below shows which ingredient is responsible. Rhodiola rosea Huperzine A Sodium Nitrate Alpha GPC

Each ingredient & the kinds of drugs it affects

For each ingredient in Hype Extreme Cotton Candy with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Rhodiola rosea10 drug types · 1,271 drugs

Antidiabetes Drugs

Theoretically, taking rhodiola with antidiabetes drugs might increase the risk of hypoglycemia.
In vitro and animal research shows that rhodiola extract can decrease blood glucose due to alpha-glucosidase activity.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, taking rhodiola with antihypertensive drugs might increase the risk of hypotension.
In vitro and animal research shows that rhodiola extract inhibits angiotensin-converting enzyme (ACE) and might lower blood pressure.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, rhodiola might increase levels of drugs metabolized by CYP2C9.
In vitro research shows that rhodiola inhibits CYP2C9. This effect is highly variable and appears to be dependent on the rhodiola product studied. Also, a clinical study in healthy young males found that taking rhodiola extract 290 mg daily for 14 days reduces the metabolism of losartan, a CYP2C9 substrate, by 21% after 4 hours.

Likelihood Possible Evidence B
Immunosuppressants

Theoretically, rhodiola use might interfere with immunosuppressive therapy.
In vitro and animal research show that rhodiola has immunostimulatory effects.

Likelihood Possible Evidence D
Losartan (Cozaar)

Rhodiola might increase the levels and adverse effects of losartan.
A clinical study in healthy young males found that taking rhodiola extract 290 mg daily for 14 days reduces the metabolism of losartan, a CYP2C9 substrate, by 21% after 4 hours.

Likelihood Probable Evidence B
P-Glycoprotein Substrates

Theoretically, rhodiola might increase levels of P-glycoprotein substrates.
In vitro research shows that rhodiola inhibits P-glycoprotein. Theoretically, using rhodiola with P-glycoprotein substrates might increase drug levels and potentially increase the risk of adverse effects.

Likelihood Possible Evidence D
Antidepressant Drugs

Theoretically, rhodiola might increase the risk of adverse effects when taken with antidepressants.
A review of adverse event reports in Poland identified cases of tachyarrhythmias, myalgia, arthralgia, gum pain, restless leg syndrome, swallowing disorders, and changes in consciousness when rhodiola was taken in combination with paroxetine, escitalopram, fluoxetine, sertraline, trazodone, and/or duloxetine.

Likelihood Possible Evidence D
Cns Depressants

Theoretically, rhodiola might increase the risk of adverse effects when taken with CNS depressants.
A review of adverse event reports in Poland identified cases of excessive sedation, myoclonus, hypotension, and hallucinations when rhodiola was taken with haloperidol, diazepam, or alprazolam.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, rhodiola might increase levels of drugs metabolized by CYP1A2.
In vitro research shows that rhodiola inhibits CYP1A2. This effect is highly variable and appears to be dependent on the rhodiola product studied. However, a clinical study in healthy young males found that taking rhodiola extract 290 mg daily for 14 days does not inhibit the metabolism of caffeine, a CYP1A2 substrate.

Likelihood Possible Evidence B
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, rhodiola might increase levels of drugs metabolized by CYP3A4.
In vitro research shows that rhodiola inhibits CYP3A4. This effect is highly variable and appears to be dependent on the rhodiola product studied. However, a clinical study in healthy young males found that taking rhodiola extract 290 mg daily for 14 days does not inhibit the metabolism of midazolam, a CYP3A4 substrate.

Likelihood Possible Evidence B
Rhodiola rosea full monograph & interactions

Huperzine A2 drug types · 219 drugs

Anticholinergic Drugs

Theoretically, huperzine A might decrease the effects of anticholinergic drugs.
Huperzine A has acetylcholinesterase (AChE) inhibiting effects. In animal models, huperzine A reversed cognitive deficits induced by scopolamine, an anticholinergic drug.

Likelihood Possible Evidence D
Cholinergic Drugs

Theoretically, concurrent use of huperzine A with cholinergic drugs might increase the effects and side effects of these medications.
Huperzine A can inhibit acetylcholinesterase (AChE) and might cause cumulative effects if used with cholinergic drugs.

Likelihood Possible Evidence B
Huperzine A full monograph & interactions

Sodium Nitrate7 drug types · 205 drugs

Antihypertensive Drugs

Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
High intake of dietary sodium can increase systolic and diastolic blood pressure. Also, high intake of sodium may necessitate increased use of antihypertensive medications to achieve blood pressure control in some patients, such as those with chronic kidney disease.

Likelihood Probable Evidence A
Corticosteroids

Concomitant use of mineralocorticoids and some glucocorticoids with sodium supplements might increase the risk of hypernatremia.
Mineralocorticoids and some glucocorticoids (corticosteroids) cause sodium retention. This effect is dose-related and depends on mineralocorticoid potency. It is most common with hydrocortisone, cortisone, and fludrocortisone, followed by prednisone and prednisolone.

Likelihood Possible Evidence D
Didanosine (Videx)

Concomitant use of didanosine with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia.
Didanosine formulations contain a significant amount of sodium.

Likelihood Probable Evidence C
Lithium

Altering dietary intake of sodium might alter the levels and clinical effects of lithium.
High sodium intake can reduce plasma concentrations of lithium by increasing lithium excretion. Reducing sodium intake can significantly increase plasma concentrations of lithium and cause lithium toxicity in patients being treated with lithium carbonate. Stabilizing sodium intake is shown to reduce the percentage of patients with lithium level fluctuations above 0.8 mEq/L. Patients taking lithium should avoid significant alterations in their dietary intake of sodium.

Likelihood Probable Evidence B
Sodium Phosphates

Theoretically, concomitant use of sodium phosphate with sodium supplements might increase the risk of hypernatremia.
Use of high doses (> 45 mL in 24 hours) of sodium phosphate, such as those used for bowel cleansing before surgery, can lead to serious electrolyte disturbances, including hypernatremia. The risk of hypernatremia is highest in the elderly and people with other risk factors for electrolyte disturbances.

Likelihood Possible Evidence D
Sodium-Containing Drugs

Concomitant use of sodium-containing drugs with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia and long-term sodium-related complications.
The Chronic Disease Risk Reduction (CDRR) intake level of 2.3 grams of sodium daily indicates the intake at which it is believed that chronic disease risk increases for the apparently healthy population. Some medications contain high quantities of sodium. When used in conjunction with sodium supplements or high-sodium diets, the CDRR may be exceeded. Additionally, concomitant use may increase the risk for hypernatremia; this risk is highest in the elderly and people with other risk factors for electrolyte disturbances.

Likelihood Possible Evidence D
Tolvaptan (Samsca)

Theoretically, concomitant use of tolvaptan with sodium might increase the risk of hypernatremia.
Tolvaptan is a vasopressin receptor 2 antagonist that is used to increase sodium levels in patients with hyponatremia. Patients taking tolvaptan should use caution with the use of sodium salts such as sodium chloride.

Likelihood Probable Evidence C
Sodium Nitrate full monograph & interactions

Alpha GPC1 drug type · 16 drugs

Scopolamine (Transderm Scop)

Theoretically, alpha-GPC might decrease the effects of scopolamine.
A small clinical study shows that alpha-GPC can partially counteract the attention and memory impairment effects caused by scopolamine given intramuscularly. Whether alpha-GPC can decrease the beneficial anti-motion sickness effects of the scopolamine patch (Transderm Scop) is unclear.

Likelihood Possible Evidence B
Alpha GPC full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Hype Extreme Cotton Candy, from the product label.

Blackstone Labs

See all Blackstone Labs products
Name
Blackstone Labs
City
Boca Raton
State
FL
ZipCode
33433
Phone Number
1-844-816-7803
Web Address
www.BlackStoneLabs.com
Pharmacist Counseling Corner

Hype Extreme Cotton Candy by Blackstone Labs: Common Questions

Does Hype Extreme Cotton Candy by Blackstone Labs interact with any medications?
Yes. Based on its ingredients, Hype Extreme Cotton Candy has a known interaction with 1,375 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Hype Extreme Cotton Candy contains 5 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe to use if I take blood pressure medication?
No—not without checking first. The sodium nitrate in this product can raise blood pressure and reduce how well your medication works, and rhodiola may lower your blood pressure further, risking dangerous drops. Talk to your doctor or pharmacist before using it.
Can I take this if I'm pregnant or breastfeeding?
The data advises against huperzine A and rhodiola in pregnancy and while breastfeeding due to insufficient safety information. There isn't enough data on file for alpha-GPC, sodium nitrate, and glycerol in these situations either. Talk with your doctor or pharmacist for personalized advice.
What is huperzine A and what does it do?
Huperzine A is a plant alkaloid that slows the breakdown of acetylcholine, a brain chemical involved in memory and thinking. It's possibly effective for Alzheimer disease, but evidence for other brain functions is insufficient.
What are the most common side effects?
Huperzine A can cause cholinergic side effects like blurred vision, dry mouth, nausea, diarrhea, and dizziness. Glycerol may cause bloating, nausea, diarrhea, and headache. Alpha-GPC rarely causes dizziness or insomnia.
Does this product have 'natural' or 'clean' label ingredients with no fillers?
This product contains inactive ingredients—silicon dioxide and natural and artificial flavors—which are flow agents and flavoring. So no, it does not have zero fillers; it contains the typical excipients found in powder supplements.
Will this help my memory or athletic performance?
Alpha-GPC is possibly effective for Alzheimer disease but evidence for general cognitive function is insufficient. Glycerol and rhodiola have insufficient evidence for athletic performance. For memory specifically, huperzine A and rhodiola both lack adequate evidence.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Hype Extreme Cotton Candy label
Go deeper

The Full Monographs Behind Hype Extreme Cotton Candy’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Alpha-gpc

Interacts with 16 drugs

Alpha-GPC is a choline-containing compound used mainly for memory, brain health, and as a choline source. There is some evidence it may help cognition in people with dementia, but evidence i...

Read the full Alpha-gpc monograph → Herb & supplement monograph

Huperzine A

Interacts with 219 drugs

Huperzine A is a purified compound from a Chinese clubmoss that acts like a mild cholinesterase inhibitor, similar in mechanism to some prescription Alzheimer's drugs. Some small studies sug...

Read the full Huperzine A monograph → Herb & supplement monograph

Sodium

Interacts with 205 drugs

Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets get more than enough—often too much—from...

Read the full Sodium monograph → Herb & supplement monograph

Glycerol

Glycerol (glycerin) is a sweet, syrupy compound made naturally in the body and widely used in foods, skin products, and medicines. It is well established as a laxative and a skin and eye moi...

Read the full Glycerol monograph → Herb & supplement monograph

Rhodiola

Interacts with 1,271 drugs

Rhodiola is an herb traditionally used to fight fatigue and help the body cope with stress. Some small studies suggest it may modestly reduce fatigue and improve mood, but the evidence is li...

Read the full Rhodiola monograph →
Sources

Sources & How We Checked

Hype Extreme Cotton Candy's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 76 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Alpha-gpc 4 references
  1. Di Perri R, Coppola G, Ambrosio LA, et al. A multicentre trial to the evaluate the efficacy and tolerability of alpha-glycerylphosphorylcholine versus cytosine diphosphocholine in patients with vascular dementia. J Int Med Res 1991;19:330-41.
  2. Barbagallo Sangiorgi G, Barbagallo M, Giordano M, et al. Alpha-glycerophosphocholine in the mental recovery of cerebral ischemic attacks: An Italian multicenter clinical trial. Ann N Y Acad Sci 1994;717:253-69. PubMed
  3. Canal N, Franceschi M, Alberoni M, et al. Effect of L-alpha-glyceryl-phosphorylcholine on amnesia caused by scopolamine. Int J Clin Pharmacol Ther Toxicol 1991;29:103-7.
  4. Lee G, Choi S, Chang J, et al. Association of L-a glycerylphosphorylcholine with subsequent stroke risk after 10 Years. JAMA Netw Open 2021;4(11):e2136008.

See these in context on the Alpha-gpc monograph →

Huperzine A 13 references
  1. Skolnick AA. Old Chinese herbal medicine used for fever yields possible new Alzheimer Disease therapy. JAMA 1997;277:776. DOI
  2. Ye JW, Cai JX, Wang LM, Tang XC. Improving effects of huperzine A on spatial working memory in aged monkeys and young adult monkeys with experimental cognitive impairment. J Pharmacol Exp Ther 1999;288:814-9.. DOI
  3. Wang T, Tang XC. Reversal of scopolamine-induced deficits in radial maze performance by (-)-huperzine A: comparison with E2020 and tacrine. Eur J Pharmacol 1998;349:137-42. PubMed
  4. Xu SS, Gao ZX, Weng Z, et al. Efficacy of tablet huperzine-A on memory, cognition, and behavior in Alzheimer's disease. Zhongguo Yao Li Xue Bao 1995;16:391-5.
  5. Zhang RW, Tang XC, Han YY, et al. [Drug evaluation of huperzine A in the treatment of senile memory disorders]. Chung Kuo Yao Li Hsueh Pao 1991;12:250-2.
  6. Xu SS, Cai ZY, Qu ZW, et al. Huperzine-A in capsules and tablets for treating patients with Alzheimer disease. Zhongguo Yao Li Xue Bao 1999;20:486-90.
  7. Felgenhauer N, Zilker T, Worek F, Eyer P. Intoxication with huperzine A, a potent anticholinesterase found in the fir club moss. J Toxicol Clin Toxicol 2000;38:803-8.. PubMed
  8. Zhang, Z., Wang, X., Chen, Q., Shu, L., Wang, J., and Shan, G. [Clinical efficacy and safety of huperzine Alpha in treatment of mild to moderate Alzheimer disease, a placebo-controlled, double-blind, randomized trial]. Zhonghua Yi Xue Za Zhi 7-25-2002;82
  9. Cheng, D. H., Ren, H., and Tang, X. C. Huperzine A, a novel promising acetylcholinesterase inhibitor. Neuroreport 12-20-1996;8(1):97-101. PubMed
  10. Wang BS, Wang H, Wei ZH, Song YY, Zhang L, Chen HZ. Efficacy and safety of natural acetylcholinesterase inhibitor huperzine A in the treatment of Alzheimer's disease: an updated meta-analysis. J Neural Transm (Vienna) 2009;116(4):457-65. PubMed
  11. Xu ZQ, Liang XM, Juan-Wu, Zhang YF, Zhu CX, Jiang XJ. Treatment with Huperzine A improves cognition in vascular dementia patients. Cell Biochem Biophys 2012;62(1):55-8. PubMed
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Sodium 38 references
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Glycerol 8 references
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See these in context on the Glycerol monograph →

Rhodiola 13 references
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See these in context on the Rhodiola monograph →

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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