IG 26 Plus DF Natural Vanilla Flavor Ingredients & Drug Interactions
by XYMOGEN
What is this page for?
First and foremost: checking IG 26 Plus DF Natural Vanilla Flavor against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
IG 26 Plus DF Natural Vanilla Flavor is a dietary supplement by XYMOGEN with 4 active ingredients. Its ingredients are commonly taken for constipation, diarrhea, high cholesterol.Based on those ingredients, 2,097 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Dietary Fiber, Arabinogalactan. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against IG 26 Plus DF Natural Vanilla Flavor by XYMOGEN
Ask about any prescription or over-the-counter medication and we check it for interactions with IG 26 Plus DF Natural Vanilla Flavor by XYMOGEN — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of IG 26 Plus DF Natural Vanilla Flavor by XYMOGEN
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
IG 26 Plus DF has 2 active ingredients: arabinogalactan and IgY Max. Arabinogalactan is a fiber derived from larch wood that's meant to support immune function and may help with cholesterol levels.
IgY Max appears to be an immune-support ingredient, though we can't describe its mechanism from the data we hold. The powder also contains inactive ingredients — natural flavors, monk fruit extract, and silica — to round out the formula.
Does it work?
Not established
The evidence for arabinogalactan isn't established in the data we hold. Studies haven't produced reliable evidence that it helps with common colds or high cholesterol, so we can't say whether it works for those purposes.
We have no effectiveness information on IgY Max.
How safe is it?
Well-documented data
Orally, arabinogalactan is generally well tolerated, though some people report bloating and flatulence. Long-term safety data are limited, so the facts advise caution.
There isn't enough safety information to know whether this product is appropriate in pregnancy or breastfeeding — talk with your doctor or pharmacist for personalized advice.
Meds to double-check
Moderate interaction found
If you take immunosuppressant drugs such as cyclosporine, tacrolimus, mycophenolate, or azathioprine, double-check this product before you start. Arabinogalactan may reduce how well your medication works.
The bottom line
Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.
This powder is designed to support immune function and general wellness. If you take immunosuppressant medications (for autoimmune conditions or after an organ transplant), check with us or your pharmacist before starting — it may interfere with how those drugs work.
Talk to your pharmacist about whether this product is right for you.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about IG 26 Plus DF Natural Vanilla Flavor, straight from the product label.
| Brand | XYMOGEN |
|---|---|
| Barcode (UPC) | 871149004132 |
| Net contents | 6.46 Ounce(s); 183 Gram(s) |
| Market status | On market |
| Date entered into DSLD | Oct 24, 2024 |
| DSLD ID | 303704 |
| Product type | Other Combinations |
| Supplement form | Powder |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for IG 26 Plus DF Natural Vanilla Flavor by XYMOGEN, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Calories | 30 Calorie(s) | -- |
| Total Carbohydrates | 1 Gram(s) | 1% |
| Cholesterol | 75 mg | 25% |
| Total Fat | 2 Gram(s) | 3% |
| Saturated Fat | 0.5 Gram(s) | 3% |
| Dietary Fiber | 1 Gram(s) | 4% |
| Protein | 2 Gram(s) | -- |
| Arabinogalactan | 1 Gram(s) | -- |
| IgY Max | 4.5 Gram(s) | -- |
Other ingredients: Natural Flavors, Monk Fruit Extract, Silica
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
DIRECTIONS: Blend or shake one scoop (about 6.1 g) in cold liquid or sprinkle on cold food, such as salad, or use as directed by your healthcare practitioner. Do not heat, cook, or add to hot food or liquid.
Precautions
Consult your healthcare practitioner prior to use.
Individuals taking medication should discuss potential interactions with their healthcare practitioner, and individuals with egg allergies should not consume this product.
Individuals taking medication should discuss potential interactions with their healthcare practitioner, and individuals with egg allergies should not consume this product.
Do not use if tamper seal is damaged.
STORAGE: Keep closed in a cool, dry place out of reach of children.
Contains: Egg
Formula
IG 26 Plus DF is an easy-to-mix, dairy-free supplement designed to support intestinal health and immunity and, in turn, positively impact multiple aspects of systemic health. The formula contains powdered hyperimmune egg, which naturally provides IgY and immunoregulatory factors, and larch arabinogalactan, a dietary prebiotic fiber. Human studies on the supplementation of these ingredients suggest they boost the body’s potential to defend itself against immune challenges.
IgY Max
Dairy-Free Immunoglobulins and Arabinogalactan
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Storage
STORAGE: Keep closed in a cool, dry place out of reach of children.
Formulation
DOES NOT CONTAIN: Wheat, gluten, yeast, soy, dairy products, fish, shellfish, peanuts, tree nuts, ingredients derived from genetically modified organisms (GMOs), artificial colors, artificial sweeteners, or artificial preservatives.
Brand IP Statement(s)
IgY Max is a trademark of IgY Nutrition, LLC and is used under license.
Copyright 2017 XYMOGEN
Xymogen Exclusive professional formulas
FDA Statement of Identity
Dietary Supplement
Seals/Symbols
ePV (ePedigree Verification)
GMP compliant third-party verified
General Statements
Scan to learn more! This package is completely recyclable
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
IG 26 Plus DF Natural Vanilla Flavor by XYMOGEN label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in IG 26 Plus DF Natural Vanilla Flavor by XYMOGEN
These are the 4 active ingredients this product is made of. Select any to open its full monograph.
Serving size6.1 Gram(s) Dosage formPowder Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Dietary Fiber
Interacts with2,025 drugs
Black psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. I...
Dietary Fiber monograph & interactionsProtein
Arabinogalactan
Interacts with121 drugs
Larch arabinogalactan is a soluble fiber from larch trees that is mainly used as a prebiotic and for immune support. Early research is interesting but...
Arabinogalactan monograph & interactionsIgY Max
Other (inactive) ingredients: Natural Flavors, Monk Fruit Extract, Silica. These complete the product’s ingredient list but are not active constituents.
IG 26 Plus DF Natural Vanilla Flavor by XYMOGEN Drug Interactions
HelloPharmacist Interaction Report
IG 26 Plus DF by XYMOGEN contains arabinogalactan, which has a documented Moderate interaction with immunosuppressant drugs (medications that calm down your immune system).
These include azathioprine, basiliximab, cyclosporine, daclizumab, muromonab-CD3, mycophenolate, and tacrolimus. Theoretically, arabinogalactan may interfere with how well these drugs work because it stimulates immune function.
Read the full breakdown — every affected drug type, severity by severity
The product also contains IgY Max, an ingredient we couldn't check for interactions — we hold no data on it.
Altogether, these interactions span 117 individual medications. If you take any immunosuppressant or other prescription drug, use the search tool below to check your exact medications before starting this supplement.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against IG 26 Plus DF Natural Vanilla Flavor?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in IG 26 Plus DF Natural Vanilla Flavor interact with 2,097 drugs. Click any drug to see the details.
2 of the 4 ingredients in IG 26 Plus DF Natural Vanilla Flavor interact with drugs. Each result below shows which ingredient is responsible. Dietary Fiber Arabinogalactan
6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with IG 26 Plus DF Natural Vanilla Flavor — through 2 ingredients. Tap an ingredient for the detail:
ArabinogalactanImmunosuppressants Moderate
Interaction Summary
Theoretically, larch arabinogalactan might interfere with immunosuppression therapy due to immunostimulant effects.
Read the full Arabinogalactan + 6-mercaptopurine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + 6-mercaptopurine interactionAbrocitinibCibinqo
How Abrocitinib interacts with IG 26 Plus DF Natural Vanilla Flavor — through 2 ingredients. Tap an ingredient for the detail:
ArabinogalactanImmunosuppressants Moderate
Interaction Summary
Theoretically, larch arabinogalactan might interfere with immunosuppression therapy due to immunostimulant effects.
Read the full Arabinogalactan + Abrocitinib interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Abrocitinib interactionAdalimumabHumira
How Adalimumab interacts with IG 26 Plus DF Natural Vanilla Flavor — through 1 ingredient. Tap an ingredient for the detail:
ArabinogalactanImmunosuppressants Moderate
Interaction Summary
Theoretically, larch arabinogalactan might interfere with immunosuppression therapy due to immunostimulant effects.
Read the full Arabinogalactan + Adalimumab interactionAdalimumab-adazHyrimoz
How Adalimumab-adaz interacts with IG 26 Plus DF Natural Vanilla Flavor — through 1 ingredient. Tap an ingredient for the detail:
ArabinogalactanImmunosuppressants Moderate
Interaction Summary
Theoretically, larch arabinogalactan might interfere with immunosuppression therapy due to immunostimulant effects.
Read the full Arabinogalactan + Adalimumab-adaz interactionAdalimumab-adbmCyltezo
How Adalimumab-adbm interacts with IG 26 Plus DF Natural Vanilla Flavor — through 1 ingredient. Tap an ingredient for the detail:
ArabinogalactanImmunosuppressants Moderate
Interaction Summary
Theoretically, larch arabinogalactan might interfere with immunosuppression therapy due to immunostimulant effects.
Read the full Arabinogalactan + Adalimumab-adbm interactionAdalimumab-afzbAbrilada
How Adalimumab-afzb interacts with IG 26 Plus DF Natural Vanilla Flavor — through 1 ingredient. Tap an ingredient for the detail:
ArabinogalactanImmunosuppressants Moderate
Interaction Summary
Theoretically, larch arabinogalactan might interfere with immunosuppression therapy due to immunostimulant effects.
Read the full Arabinogalactan + Adalimumab-afzb interactionAdalimumab-attoAmjevita
How Adalimumab-atto interacts with IG 26 Plus DF Natural Vanilla Flavor — through 1 ingredient. Tap an ingredient for the detail:
ArabinogalactanImmunosuppressants Moderate
Interaction Summary
Theoretically, larch arabinogalactan might interfere with immunosuppression therapy due to immunostimulant effects.
Read the full Arabinogalactan + Adalimumab-atto interactionAdalimumab-bwwdHadlima
How Adalimumab-bwwd interacts with IG 26 Plus DF Natural Vanilla Flavor — through 2 ingredients. Tap an ingredient for the detail:
ArabinogalactanImmunosuppressants Moderate
Interaction Summary
Theoretically, larch arabinogalactan might interfere with immunosuppression therapy due to immunostimulant effects.
Read the full Arabinogalactan + Adalimumab-bwwd interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Adalimumab-bwwd interactionAdalimumab-fkjpHulio
How Adalimumab-fkjp interacts with IG 26 Plus DF Natural Vanilla Flavor — through 1 ingredient. Tap an ingredient for the detail:
ArabinogalactanImmunosuppressants Moderate
Interaction Summary
Theoretically, larch arabinogalactan might interfere with immunosuppression therapy due to immunostimulant effects.
Read the full Arabinogalactan + Adalimumab-fkjp interactionAlefaceptAmevive
How Alefacept interacts with IG 26 Plus DF Natural Vanilla Flavor — through 1 ingredient. Tap an ingredient for the detail:
ArabinogalactanImmunosuppressants Moderate
Interaction Summary
Theoretically, larch arabinogalactan might interfere with immunosuppression therapy due to immunostimulant effects.
Read the full Arabinogalactan + Alefacept interactionAlemtuzumabCampath
How Alemtuzumab interacts with IG 26 Plus DF Natural Vanilla Flavor — through 2 ingredients. Tap an ingredient for the detail:
ArabinogalactanImmunosuppressants Moderate
Interaction Summary
Theoretically, larch arabinogalactan might interfere with immunosuppression therapy due to immunostimulant effects.
Read the full Arabinogalactan + Alemtuzumab interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Alemtuzumab interactionAlogliptin, MetforminKazano
How Alogliptin, Metformin interacts with IG 26 Plus DF Natural Vanilla Flavor — through 1 ingredient. Tap an ingredient for the detail:
Dietary FiberOral Drugs, Metformin (glucophage) Moderate
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Alogliptin, Metformin interactionAnifrolumab-fniaSaphnelo
How Anifrolumab-fnia interacts with IG 26 Plus DF Natural Vanilla Flavor — through 1 ingredient. Tap an ingredient for the detail:
ArabinogalactanImmunosuppressants Moderate
Interaction Summary
Theoretically, larch arabinogalactan might interfere with immunosuppression therapy due to immunostimulant effects.
Read the full Arabinogalactan + Anifrolumab-fnia interactionAntithymocyte GlobulinThymoglobulin
How Antithymocyte Globulin interacts with IG 26 Plus DF Natural Vanilla Flavor — through 1 ingredient. Tap an ingredient for the detail:
ArabinogalactanImmunosuppressants Moderate
Interaction Summary
Theoretically, larch arabinogalactan might interfere with immunosuppression therapy due to immunostimulant effects.
Read the full Arabinogalactan + Antithymocyte Globulin interactionAtezolizumabTecentriq
How Atezolizumab interacts with IG 26 Plus DF Natural Vanilla Flavor — through 1 ingredient. Tap an ingredient for the detail:
ArabinogalactanImmunosuppressants Moderate
Interaction Summary
Theoretically, larch arabinogalactan might interfere with immunosuppression therapy due to immunostimulant effects.
Read the full Arabinogalactan + Atezolizumab interactionAzamuneImmunoprin
How Azamune interacts with IG 26 Plus DF Natural Vanilla Flavor — through 2 ingredients. Tap an ingredient for the detail:
ArabinogalactanImmunosuppressants Moderate
Interaction Summary
Theoretically, larch arabinogalactan might interfere with immunosuppression therapy due to immunostimulant effects.
Read the full Arabinogalactan + Azamune interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Azamune interactionAzathioprineAzamune, Imuran
How Azathioprine interacts with IG 26 Plus DF Natural Vanilla Flavor — through 2 ingredients. Tap an ingredient for the detail:
ArabinogalactanImmunosuppressants Moderate
Interaction Summary
Theoretically, larch arabinogalactan might interfere with immunosuppression therapy due to immunostimulant effects.
Read the full Arabinogalactan + Azathioprine interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Azathioprine interactionBasiliximabSimulect
How Basiliximab interacts with IG 26 Plus DF Natural Vanilla Flavor — through 2 ingredients. Tap an ingredient for the detail:
ArabinogalactanImmunosuppressants Moderate
Interaction Summary
Theoretically, larch arabinogalactan might interfere with immunosuppression therapy due to immunostimulant effects.
Read the full Arabinogalactan + Basiliximab interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Basiliximab interactionBeclometasone DipropionateBecotide
How Beclometasone Dipropionate interacts with IG 26 Plus DF Natural Vanilla Flavor — through 2 ingredients. Tap an ingredient for the detail:
ArabinogalactanImmunosuppressants Moderate
Interaction Summary
Theoretically, larch arabinogalactan might interfere with immunosuppression therapy due to immunostimulant effects.
Read the full Arabinogalactan + Beclometasone Dipropionate interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Beclometasone Dipropionate interactionBeclomethasoneBeclovent, Vanceril
How Beclomethasone interacts with IG 26 Plus DF Natural Vanilla Flavor — through 2 ingredients. Tap an ingredient for the detail:
ArabinogalactanImmunosuppressants Moderate
Interaction Summary
Theoretically, larch arabinogalactan might interfere with immunosuppression therapy due to immunostimulant effects.
Read the full Arabinogalactan + Beclomethasone interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Beclomethasone interactionBeclomethasone DipropionateQNASL, Qvar
How Beclomethasone Dipropionate interacts with IG 26 Plus DF Natural Vanilla Flavor — through 2 ingredients. Tap an ingredient for the detail:
ArabinogalactanImmunosuppressants Moderate
Interaction Summary
Theoretically, larch arabinogalactan might interfere with immunosuppression therapy due to immunostimulant effects.
Read the full Arabinogalactan + Beclomethasone Dipropionate interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Beclomethasone Dipropionate interactionBetamethasoneCelestone, Diprolene AF, Diprosone
How Betamethasone interacts with IG 26 Plus DF Natural Vanilla Flavor — through 2 ingredients. Tap an ingredient for the detail:
ArabinogalactanImmunosuppressants Moderate
Interaction Summary
Theoretically, larch arabinogalactan might interfere with immunosuppression therapy due to immunostimulant effects.
Read the full Arabinogalactan + Betamethasone interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Betamethasone interactionBetamethasone DipropionateSernivo
How Betamethasone Dipropionate interacts with IG 26 Plus DF Natural Vanilla Flavor — through 1 ingredient. Tap an ingredient for the detail:
ArabinogalactanImmunosuppressants Moderate
Interaction Summary
Theoretically, larch arabinogalactan might interfere with immunosuppression therapy due to immunostimulant effects.
Read the full Arabinogalactan + Betamethasone Dipropionate interactionBetamethasone Dipropionate, CalcipotrieneEnstilar, Wynzora
How Betamethasone Dipropionate, Calcipotriene interacts with IG 26 Plus DF Natural Vanilla Flavor — through 1 ingredient. Tap an ingredient for the detail:
ArabinogalactanImmunosuppressants Moderate
Interaction Summary
Theoretically, larch arabinogalactan might interfere with immunosuppression therapy due to immunostimulant effects.
Read the full Arabinogalactan + Betamethasone Dipropionate, Calcipotriene interactionBetamethasone ValerateLuxiq
How Betamethasone Valerate interacts with IG 26 Plus DF Natural Vanilla Flavor — through 1 ingredient. Tap an ingredient for the detail:
ArabinogalactanImmunosuppressants Moderate
Interaction Summary
Theoretically, larch arabinogalactan might interfere with immunosuppression therapy due to immunostimulant effects.
Read the full Arabinogalactan + Betamethasone Valerate interactionBimekizumab-bkzxBimzelx
How Bimekizumab-bkzx interacts with IG 26 Plus DF Natural Vanilla Flavor — through 1 ingredient. Tap an ingredient for the detail:
ArabinogalactanImmunosuppressants Moderate
Interaction Summary
Theoretically, larch arabinogalactan might interfere with immunosuppression therapy due to immunostimulant effects.
Read the full Arabinogalactan + Bimekizumab-bkzx interactionCanagliflozin, MetforminInvokamet
How Canagliflozin, Metformin interacts with IG 26 Plus DF Natural Vanilla Flavor — through 1 ingredient. Tap an ingredient for the detail:
Dietary FiberOral Drugs, Metformin (glucophage) Moderate
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Canagliflozin, Metformin interactionCanagliflozin, Metformin HydrochlorideInvokamet XR
How Canagliflozin, Metformin Hydrochloride interacts with IG 26 Plus DF Natural Vanilla Flavor — through 1 ingredient. Tap an ingredient for the detail:
Dietary FiberMetformin (glucophage), Oral Drugs Moderate
Interaction Summary
Theoretically, black psyllium might increase the therapeutic and adverse effects of metformin.
Read the full Dietary Fiber + Canagliflozin, Metformin Hydrochloride interactionCarbamazepineCarbatrol, Carnexiv, Equetro, Tegretol, Tegretol XR
How Carbamazepine interacts with IG 26 Plus DF Natural Vanilla Flavor — through 1 ingredient. Tap an ingredient for the detail:
Dietary FiberOral Drugs, Carbamazepine (tegretol) Moderate
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Carbamazepine interactionCiclesonideAlvesco, Omnaris, Zetonna
How Ciclesonide interacts with IG 26 Plus DF Natural Vanilla Flavor — through 1 ingredient. Tap an ingredient for the detail:
ArabinogalactanImmunosuppressants Moderate
Interaction Summary
Theoretically, larch arabinogalactan might interfere with immunosuppression therapy due to immunostimulant effects.
Read the full Arabinogalactan + Ciclesonide interactionEach ingredient & the kinds of drugs it affects
For each ingredient in IG 26 Plus DF Natural Vanilla Flavor with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Dietary Fiber
Carbamazepine (Tegretol)
Theoretically, black psyllium might reduce the effects of carbamazepine and increase the risk for convulsions.
Theoretically, black psyllium might reduce carbamazepine absorption. A preliminary study using blond psyllium reported decreased carbamazepine bioavailability due to binding of the drug to psyllium, as well as reduction of available fluid in the gut for dissolution of the drug. This interaction may also occur with black psyllium.
Lithium
Theoretically, taking black psyllium at the same time as lithium might reduce lithium absorption.
The fiber in black psyllium might reduce lithium absorption and plasma levels. Some case reports describe a reduction in plasma lithium levels with concomitant administration of blond psyllium. This was reversed when psyllium was stopped. This interaction may also occur with black psyllium.
Metformin (Glucophage)
Theoretically, black psyllium might increase the therapeutic and adverse effects of metformin.
Animal research shows that concurrent consumption of blond psyllium with metformin slows and increases the absorption of metformin. This interaction may also occur with black psyllium. To avoid changes in absorption, take psyllium 30-60 minutes after metformin.
Olanzapine (Zyprexa)
Theoretically, taking black psyllium at the same time as olanzapine might reduce olanzapine absorption.
The fiber in black psyllium might decrease the absorption of olanzapine. A single case report describes a reduction in the effectiveness of olanzapine when it was concomitantly administered with an unspecified type of psyllium 3 grams orally twice daily. This effect was reversed when psyllium was stopped.
Digoxin (Lanoxin)
Theoretically, taking black psyllium at the same time as digoxin might reduce digoxin absorption and decrease digoxin levels.
Psyllium might bind digoxin in the gut. However, some clinical evidence suggests that psyllium does not impact digoxin absorption.
Ethinyl Estradiol
Theoretically, taking black psyllium at the same time as ethinyl estradiol might alter levels of estradiol.
Concurrent use of blond psyllium with ethinyl estradiol results in a slight increase in the extent of ethinyl estradiol absorption and a slower rate of absorption. This is unlikely to be clinically significant.
Oral Drugs
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Psyllium seems to have variable effects on drug absorption. To avoid changes in absorption, take psyllium 30-60 minutes after oral medications. Animal research shows that blond psyllium delays and increases the absorption of metformin and ethinyl estradiol. Case reports and animal research suggest that blond psyllium might reduce absorption of lithium, digoxin, olanzapine, and carbamazepine. Finally, some pharmacokinetic studies show that psyllium does not affect the absorption of levothyroxine or warfarin. Although many of these studies evaluated blond psyllium, the fiber content in black psyllium may have similar effects.
Arabinogalactan
Immunosuppressants
Theoretically, larch arabinogalactan might interfere with immunosuppression therapy due to immunostimulant effects. Immunosuppressant drugs include azathioprine (Imuran), basiliximab (Simulect), cyclosporine (Neoral, Sandimmune), daclizumab (Zenapax), muromonab-CD3 (OKT3, Orthoclone OKT3), mycophenolate (CellCept), tacrolimus (FK506, Prograf), sirolimus (Rapamune), prednisone (Deltasone, Orasone), corticosteroids (glucocorticoids), and other drugs.
Brand information
Manufacturer and brand details for IG 26 Plus DF Natural Vanilla Flavor, from the product label.
XYMOGEN
See all XYMOGEN products- Name
- XYMOGEN Exclusive Professional Formulas
- Street Address
- 6900 Kingspointe Pkwy.
- City
- Orlando
- State
- FL
- ZipCode
- 32819
- Phone Number
- 800-647-6100
- Web Address
- www.xymogen.com
IG 26 Plus DF Natural Vanilla Flavor by XYMOGEN: Common Questions
Does IG 26 Plus DF Natural Vanilla Flavor by XYMOGEN interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What does arabinogalactan do?
Will this give me gas or bloating?
Can I take this if I'm pregnant or breastfeeding?
What's IgY Max?
Does the powder contain fillers?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if IG 26 Plus DF Natural Vanilla Flavor is safe with your meds?
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind IG 26 Plus DF Natural Vanilla Flavor’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Black Psyllium
Interacts with 2,025 drugsBlack psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. It is best known and most studied for rel...
Read the full Black Psyllium monograph → Herb & supplement monographLarch Arabinogalactan
Interacts with 121 drugsLarch arabinogalactan is a soluble fiber from larch trees that is mainly used as a prebiotic and for immune support. Early research is interesting but limited, and most claims are not yet fi...
Read the full Larch Arabinogalactan monograph →Sources & How We Checked
IG 26 Plus DF Natural Vanilla Flavor's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 26 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Black Psyllium 18 references
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
- Covington TR, et al. Handbook of Nonprescription Drugs. 11th ed. Washington, DC: American Pharmaceutical Association, 1996.
- Etman M. Effect of a bulk forming laxative on the bioavailablility of carbamazepine in man. Drug Dev Ind Pharm 1995;21:1901-6.
- Perlman BB. Interaction between lithium salts and ispaghula husk. Lancet 1990;335:416.
- Vaswani SK, Hamilton RG, Valentine MD, Adkinson NF. Psyllium laxative-induced anaphylaxis, asthma, and rhinitis. Allergy 1996;51:266-8. PubMed
- Lantner RR, Espiritu BR, Zumerchik P, Tobin MC. Anaphylaxis following ingestion of a psyllium-containing cereal. JAMA 1990;264:2534-6. DOI
- Kaplan MJ. Anaphylactic reaction to "Heartwise." N Engl J Med 1990;323:1072-3. DOI
- Nordstrom M, Melander A, Robertsson E, Steen B. Influence of wheat bran and of a bulk-forming ispaghula cathartic on the bioavailability of digoxin in geriatric in-patients. Drug Nutr Interact 1987;5:67-9..
- Robinson DS, Benjamin DM, McCormack JJ. Interaction of warfarin and nonsystemic gastrointestinal drugs. Clin Pharmacol Ther 1971;12:491-5. PubMed
- Garcia JJ, Fernandez N, Diez MJ, et al. Influence of two dietary fibers in the oral bioavailability and other pharmacokinetic parameters of ethinyloestradiol. Contraception 2000;62:253-7. PubMed
- Fernandez N, Lopez C, Díez R, et al. Drug interactions with the dietary fiber Plantago ovata husk. Expert Opin Drug Metab Toxicol 2012;8(11):1377-86.
- Semen plantaginis in: WHO Monographs on Selected Medicinal Plants, volume 1. World Health Organization, Geneva, 1999. Available at http://apps.who.int/medicinedocs/en/d/Js2200e/. Accessed November 26, 1026.
- Code of Federal Regulations, Title 21 (21CFR 101.17). Food labeling warning, notice, and safe handling statements. Available at www.ecfr.gov/cgi-bin/text-idx?SID=20f647d3b74161501f46564b915b4048&mc=true&node=se21.2.101_117&rgn=div8. Accessed December 3, 2
- Code of Federal Regulations, Title 21 (21CFR 201.319). Specific labeling requirements - water-soluble gums, hydrophilic gums, and hydrophilic mucilloids. Available at www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=201.319. Accessed Dece
- Diez R, Garcia JJ, Diez MJ, Sierra M, Sahagun AM, Fernandez N. Influence of Plantago ovata husk (dietary fiber) on the bioavailability and other pharmacokinetic parameters of metformin in diabetic rabbits. BMC Complement Altern Med. 2017 Jun 7;17(1):298. PubMed
- Chiu AC, Sherman SI. Effects of pharmacological fiber supplements on levothyroxine absorption. Thyroid. 1998;8(8):667-71. PubMed
- Merrick C, Madden CA, Capurso NA. A Case of Blunted Orally Disintegrating Olanzapine Effect Due to Coadministered Psyllium. J Clin Psychiatry 2021;82(2):20cr13633. PubMed
Larch Arabinogalactan 8 references
- D'Adamo P. Larch arabinogalactan. J Naturopath Med 1996;6:33-7.
- Kelly GS. Larch arabinogalactan: Clinical relevance of a novel immune-enhancing polysaccharide. Alt Med Rev 1999;4:96-103.
- Marett R, Slavin JL. No long-term benefits of supplementation with arabinogalactan on serum lipids and glucose. J Am Diet Assoc 2004;104:636-9.
- Robinson RR, Feirtag J, Slavin JL. Effects of dietary arabinogalactan on gastrointestinal and blood parameters in healthy human subjects. J Am Coll Nutr 2001;20:279-85. PubMed
- Udani JK, Singh BB, Barrett ML, Singh VJ. Proprietary arabinogalactan extract increases antibody response to the pneumonia vaccine: a randomized, double-blind, placebo-controlled, pilot study in healthy volunteers. Nutr J 2010;9:32. PubMed
- Grube B, Stier H, Riede L, Gruenwald J. Tolerability of a proprietary larch arabinogalactan extract: a randomized, double-blind, placebo-controlled clinical trial in healthy subjects. Food Nutr Sci 2012;3:1533-8. DOI
- Dion C, Chappuis E, Ripoll C. Does larch arabinogalactan enhance immune function? A review of mechanistic and clinical trials. Nutr Metab (Lond) 2016;13:28. PubMed
- Riede L, Grube B, Gruenwald J. Larch arabinogalactan effects on reducing incidence of upper respiratory tract infections. Curr Med Res Opin 2013;29(3):251-8.
See these in context on the Larch Arabinogalactan monograph →
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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