Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

IGF-1 Extreme Ingredients & Drug Interactions

by Aspen Antler Research

IGF-1 Extreme label
See full label image
Liquid Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking IGF-1 Extreme against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

IGF-1 Extreme is a dietary supplement by Aspen Antler Research with 4 active ingredients. Its ingredients are commonly taken for high cholesterol, vitamin b3 deficiency (pellagra), heart health support.Based on those ingredients, 755 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Niacin, Bioenergy Ribose, Antler Velvet Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against IGF-1 Extreme by Aspen Antler Research

Ask about any prescription or over-the-counter medication and we check it for interactions with IGF-1 Extreme by Aspen Antler Research — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of IGF-1 Extreme by Aspen Antler Research

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 1 of its 4 active ingredients.
  • “Proprietary Blend” is a proprietary blend — the label gives one combined amount (400 mg) without saying how much of each component you get.

IGF-1 Extreme contains 4 active ingredients. Niacin (also called vitamin B3) is included for its role in metabolism and cellular energy — it's typically used to support cholesterol and energy levels.

The product also contains Tart Cherry fruit concentrate, Bioenergy Ribose (a simple sugar your cells use for energy), and Antler Velvet Extract (derived from deer antler tissue). The remaining ingredients are water, glycerin, grape alcohol, vanilla flavor, citric acid, potassium sorbate, and stevia — these are inactive ingredients that preserve and flavor the liquid.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: lean muscle growth and faster recovery.
  • We looked for evidence on: Athletic performance, Exercise-induced muscle soreness, Muscle soreness, Fatigue, strength gains, exercise recovery.
  • The strongest evidence on file: Sour Cherry is rated "Possibly Effective" for Athletic performance (Natural Medicines).
  • Also on file: Ribose is rated "Possibly Ineffective" for Athletic performance.
  • Also on file: Sour Cherry is rated "Insufficient Reliable Evidence To Rate" for Exercise-induced muscle soreness.

In our data, niacin is rated Likely Effective for pellagra (a vitamin B3 deficiency disease) and Possibly Effective for certain types of high cholesterol related to HIV/AIDS and metabolic syndrome. Tart cherry is rated Possibly Effective for athletic performance, though evidence for ADHD, cognitive function, muscle soreness, and respiratory infections after exercise is insufficient to rate.

Ribose is rated Possibly Ineffective for athletic performance and McArdle disease; evidence for restless legs, heart failure, muscle soreness, and recovery after bypass surgery is insufficient to rate. Antler velvet extract shows insufficient evidence for wound healing, heart disease, high blood pressure, bone health, sexual desire, and aging.

The evidence supporting this product's claimed benefits as 'IGF-1 Extreme' isn't established in the data we hold.

The evidence, ingredient by ingredient Niacin Sour Cherry Ribose Deer Velvet

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 4 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 4 of 4.
  • General safety write-ups exist for 4 of 4.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Niacin from food and standard prenatal vitamins is fine, but high-dose niacin should be avoided unless prescribed — high supplemental doses can cause flushing, liver problems, and other effects. The most common side effects of niacin are flushing (affecting up to 70% of users), stomach upset (nausea, vomiting, heartburn, abdominal pain, diarrhea, constipation), and elevated liver enzymes.

Serious but rare effects include liver damage, muscle damage, low platelet count, and vision changes. Tart cherry is generally well tolerated as whole fruit but is less studied in concentrated form — common side effects include abdominal pain, weakness, loose stools, and stomach upset; one case of a possible allergic skin reaction was reported.

Ribose is generally well tolerated for up to one month but can lower blood sugar; common side effects are diarrhea, stomach discomfort, headache, nausea, and low blood sugar. Antler velvet extract appears generally well tolerated short-term, but long-term safety and product quality are not well studied.

Ribose and antler velvet extract are best avoided during pregnancy and breastfeeding due to insufficient safety data; niacin at high supplement doses should also be avoided in pregnancy unless prescribed.

Side effects, ingredient by ingredient Niacin Sour Cherry Ribose Deer Velvet

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 4 matched ingredients can interact with medications — Deer Velvet, Ribose, Niacin.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 756 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your pharmacist before using this product if you take any blood pressure medications, blood thinners or antiplatelet drugs (like aspirin or clopidogrel), diabetes medications or insulin, cholesterol-lowering drugs (statins), gout medications (allopurinol or probenecid), bile acid sequestrants, medications that damage the liver, or birth control pills and estrogen-containing medications. No interactions are documented for tart cherry in our data, but that doesn't mean none exist.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product is best for someone with no blood pressure medications, diabetes or diabetes drugs, blood thinners, liver concerns, or cholesterol medications — and who can handle niacin's common flushing and stomach effects. If you take any prescription medications, especially blood pressure drugs, diabetes medications, insulin, blood thinners, statins, or gout medications, talk with your pharmacist before starting.

The same goes if you're pregnant, breastfeeding, or planning to become pregnant.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 4 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 22, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about IGF-1 Extreme, straight from the product label.

Brand Aspen Antler Research
Barcode (UPC) 713807378011
Net contents 2 Fluid Ounce(s); 60 mL
Market status On market
Date entered into DSLD Aug 22, 2025
DSLD ID 336699
Product type Other Combinations
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for IGF-1 Extreme by Aspen Antler Research, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 mL
Maximum serving Sizes:
1 mL
Servings per container
60
UPC/BARCODE
713807378011
IngredientAmount% DV
Niacin16 mg NE100%
Proprietary Blend400 mg--
Tart Cherry fruit concentrate0 NP--
Bioenergy Ribose0 NP--
Antler Velvet Extract0 NP--

Other ingredients: Water, Glycerin, Grape Alcohol, Vanilla Flavor, Natural, Citric Acid, Potassium Sorbate, Stevia

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: (Adult) Shake very well before use. As a dietary supplement, take 1ml (1/2 dropper) under tongue, hold for 20 seconds before swallowing. 2 times per day, morning and evening for best results. Do not eat or drink for 15 minutes before or after taking.

Precautions

Do not use if tamper evident seal is broken.

General Statements

New Formula

Formula

American Deer Antler Extract

Formulation

Lean Muscle Growth Faster Recovery Times Strengthens Immune System

All Natural Growth Factors

Brand IP Statement(s)

Bioenergy Ribose is a registered trademark of Bioenergy, Inc

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

IGF-1 Extreme by Aspen Antler Research label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

IGF-1 Extreme label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in IGF-1 Extreme by Aspen Antler Research

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 mL Dosage formLiquid Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Niacin

Interacts with
727 drugs
16 mg NE per serving

Niacin (vitamin B3) is an essential nutrient your body needs for energy and metabolism, and deficiency is uncommon in most developed countries. Prescr...

Niacin monograph & interactions

Proprietary Blend

400 mg per serving

Other (inactive) ingredients: Water, Glycerin, Grape Alcohol, Vanilla Flavor, Natural, Citric Acid, Potassium Sorbate, Stevia. These complete the product’s ingredient list but are not active constituents.

Interaction report

IGF-1 Extreme by Aspen Antler Research Drug Interactions

Want to check YOUR meds against IGF-1 Extreme?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
755Drugs
727 Moderate 28 Minor

Ingredients driving the most interactions

Niacin 727
Bioenergy Ribose 86
Antler Velvet Extract 52

Individual Drug Interactions

The ingredients in IGF-1 Extreme interact with 755 drugs. Click any drug to see the details.

3 of the 4 ingredients in IGF-1 Extreme interact with drugs. Each result below shows which ingredient is responsible. Niacin Bioenergy Ribose Antler Velvet Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in IGF-1 Extreme with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Niacin15 drug types · 727 drugs

Alcohol (Ethanol)

Concomitant use of alcohol and niacin might increase the risk of flushing and hepatotoxicity.
Alcohol can exacerbate the flushing and pruritus associated with niacin. Large doses of niacin might also exacerbate liver dysfunction associated with chronic alcohol use. A case report describes delirium and lactic acidosis in a patient taking niacin 3 grams daily who ingested 1 liter of wine. Advise patients to avoid large amounts of alcohol while taking niacin.

Likelihood Probable Evidence D
Allopurinol (Zyloprim)

Theoretically, niacin might antagonize the therapeutic effects of uricosurics such as allopurinol.
Large doses of niacin can reduce urinary excretion of uric acid, potentially resulting in hyperuricemia. Doses of uricosurics such as allopurinol might need to be increased to maintain control of gout in patients who start taking niacin. People who have frequent attacks of gout despite uricosuric therapy should avoid niacin.

Likelihood Probable Evidence C
Anticoagulant/Antiplatelet Drugs

Theoretically, niacin may have additive effects when used with anticoagulant or antiplatelet drugs.
Several cases of clotting factor synthesis deficiency and coagulopathy have been reported in patients taking sustained-release niacin. Also, thrombocytopenia has been reported in patients treated with niacin or niacin plus lovastatin.

Likelihood Possible Evidence D
Antidiabetes Drugs

Niacin can increase blood glucose levels and may diminish the effects of antidiabetes drugs.
Niacin impairs glucose tolerance in a dose-dependent manner, probably by causing or aggravating insulin resistance and increasing hepatic production of glucose. In diabetes patients, niacin 4.5 grams daily for 5 weeks can increase plasma glucose by an average of 16% and glycated hemoglobin (HbA1c) by 21%. However, lower doses of 1.5 grams daily or less appear to have minimal effects on blood glucose. In some patients, glucose levels increase when niacin is started, but then return to baseline when a stable dose is reached. Up to 35% of patients with diabetes may need adjustments in hypoglycemic therapy when niacin is added.

Likelihood Probable Evidence B
Antihypertensive Drugs

Theoretically, niacin may increase the risk of hypotension when used with antihypertensive drugs.
The vasodilating effects of niacin can cause hypotension. Furthermore, some clinical evidence suggests that a one-hour infusion of niacin can reduce systolic, diastolic, and mean blood pressure in hypertensive patients. This effect is not observed in normotensive patients.

Likelihood Possible Evidence B
Bile Acid Sequestrants

Bile acid sequestrants can bind niacin and decrease absorption. Separate administration by 4-6 hours to avoid an interaction.
In vitro studies show that colestipol (Colestid) binds about 98% of available niacin and cholestyramine (Questran) binds 10% to 30%.

Likelihood Possible Evidence D
Gemfibrozil (Lopid)

Theoretically, concomitant use of niacin and gemfibrozil might increase the risk of myopathy in some patients.
A case of myopathy from concomitant use of niacin and gemfibrozil has been reported. Niacin alone has also been associated with cases of myopathy. Using gemfibrozil with niacin might further increase the risk of developing myopathy.

Likelihood Possible Evidence D
Hepatotoxic Drugs

Theoretically, concomitant use of niacin and hepatotoxic drugs might increase the risk of hepatotoxicity.
Niacin has been associated with cases of liver toxicity, especially when used in pharmacologic doses. Sustained-release niacin preparations appear to be associated with a higher risk of hepatotoxicity than immediate-release niacin.

Likelihood Possible Evidence D
Hmg-Coa Reductase Inhibitors ("Statins")

Theoretically, concomitant use of niacin and statins might increase the risk of myopathy and rhabdomyolysis in some patients.
Some case reports have raised concerns that niacin might increase the risk of myopathy and rhabdomyolysis when combined with statins. However, a significantly increased risk of myopathy has not been demonstrated in clinical trials, including those using an FDA-approved combination of lovastatin and niacin (Advicor).

Likelihood Possible Evidence D
Probenecid (Benemid)

Theoretically, niacin might antagonize the therapeutic effects of uricosurics such as probenecid.
Large doses of niacin reduce urinary excretion of uric acid, potentially causing hyperuricemia. Doses of uricosurics such as probenecid might need to be increased to maintain control of gout in patients who start taking niacin. People who have frequent attacks of gout despite uricosuric therapy should avoid niacin.

Likelihood Probable Evidence C
Sulfinpyrazone (Anturane)

Theoretically, niacin might antagonize the therapeutic effects of uricosurics such as sulfinpyrazone.
Large doses of niacin reduce urinary excretion of uric acid, potentially causing hyperuricemia. Doses of uricosurics such as sulfinpyrazone might need to be increased to maintain control of gout in patients who start taking niacin. People who have frequent attacks of gout despite uricosuric therapy should avoid niacin.

Likelihood Probable Evidence C
Thyroid Hormone

Theoretically, niacin might antagonize the therapeutic effects of thyroid hormones.
Clinical research and case reports suggests that taking niacin can reduce serum levels of thyroxine-binding globulin by up to 25% and moderately reduce levels of thyroxine (T4). Patients taking thyroid hormone for hypothyroidism might need dose adjustments when using niacin.

Likelihood Probable Evidence D
Transdermal Nicotine (Nicoderm)

Theoretically, concomitant use of niacin and transdermal nicotine might increase the risk of flushing and dizziness.
Niacin and nicotine can both cause flushing and dizziness.

Likelihood Possible Evidence D
Warfarin (Coumadin)

There is limited evidence that niacin may increase the anticoagulant effects of warfarin.
In a case report, a patient on warfarin developed an elevated international normalized ratio (INR) of 3.9 after taking niacin for two weeks. The patient's INR was previously stable, ranging between 2 and 3 in recent months, and no other medication changes were identified. The elevated INR returned to therapeutic range within 4 days following the discontinuation of niacin.

Likelihood Possible Evidence D
Aspirin

Large doses of aspirin might alter the clearance of niacin.
Aspirin is often used with niacin to reduce niacin-induced flushing. Doses of 80-975 mg aspirin have been used, but 325 mg appears to be optimal. Aspirin also seems to reduce the clearance of niacin by competing for glycine conjugation. Taking aspirin 1 gram seems to reduce niacin clearance by 45%. This is probably a dose-related effect and not clinically significant with the more common aspirin dose of 325 mg.

Likelihood Likely Evidence B
Niacin full monograph & interactions

Bioenergy Ribose2 drug types · 86 drugs

Antidiabetes Drugs

Theoretically, taking ribose in combination with antidiabetes drugs might increase the risk of hypoglycemia.
In clinical research, ribose decreases serum glucose levels in a dose-dependent manner.

Likelihood Probable Evidence B
Insulin

Theoretically, taking ribose with insulin could increase the hypoglycemic effect of insulin.
In clinical pharmacokinetic studies, oral administration of ribose modestly increased serum insulin levels.

Likelihood Possible Evidence B
Bioenergy Ribose full monograph & interactions

Antler Velvet Extract2 drug types · 52 drugs

Contraceptive Drugs

Theoretically, deer velvet might interfere with the effectiveness of contraceptive drugs.
Laboratory research shows that deer velvet contains small quantities of estradiol and testosterone. While clinical research shows that taking deer velvet extract does not raise testosterone levels, estradiol levels were not measured.

Likelihood Unlikely Evidence D
Estrogens

Theoretically, deer velvet might increase the effects and side effects of estrogens.
Laboratory evidence shows that deer velvet contains small quantities of estradiol and testosterone. While clinical research shows that taking deer velvet extract does not raise testosterone levels, estradiol levels were not measured.

Likelihood Unlikely Evidence D
Antler Velvet Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for IGF-1 Extreme, from the product label.

Aspen Antler Research

See all Aspen Antler Research products
Name
Herbal Nutrition
City
Alpharetta
State
GA
ZipCode
30005
Phone Number
1-800-497-4709
Web Address
www.herbalnutritionhealth.com
Pharmacist Counseling Corner

IGF-1 Extreme by Aspen Antler Research: Common Questions

Does IGF-1 Extreme by Aspen Antler Research interact with any medications?
Yes. Based on its ingredients, IGF-1 Extreme has a known interaction with 755 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
IGF-1 Extreme contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this work for athletic performance?
Tart cherry is rated Possibly Effective for athletic performance. Ribose is rated Possibly Ineffective for athletic performance, so evidence doesn't support its use for that goal. The evidence supporting this product as a whole for athletic performance isn't established in the data we hold.
What's the flushing I've heard about with niacin?
Flushing — warmth, redness, burning, tingling, or itching of the face and body — is the most common side effect of niacin. Up to 70% of people using niacin may experience it, especially at higher doses. The flushing is caused by blood vessel dilation and usually goes away as your body adjusts, though it can be uncomfortable.
Can I take this if I'm pregnant?
High-dose niacin should be avoided in pregnancy unless prescribed by a doctor. Ribose and antler velvet extract lack enough safety information, so they're best avoided during pregnancy. Talk with your pharmacist or doctor before taking this product if you're pregnant or planning to become pregnant.
Is tart cherry safe?
Tart cherry is generally well tolerated as whole fruit. In concentrated form (like in this product), it's less well studied, but common side effects are mild — abdominal pain, loose stools, and stomach upset. One case of a possible allergic skin reaction was reported. If you have a cherry allergy, take caution.
Can this lower my blood sugar?
Yes. Ribose can lower blood glucose levels in a dose-dependent manner, and it may increase the risk of low blood sugar (hypoglycemia) when combined with diabetes medications or insulin. If you have diabetes or take diabetes drugs, talk with your pharmacist before using this product.
What's ribose for in this product?
Ribose is a simple sugar your cells use for energy production. It's included for potential benefits to athletic performance and heart function, but evidence that it works for athletic performance is rated Possibly Ineffective, and evidence for heart failure and muscle soreness is insufficient.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

IGF-1 Extreme label
Go deeper

The Full Monographs Behind IGF-1 Extreme’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Niacin

Interacts with 727 drugs

Niacin (vitamin B3) is an essential nutrient your body needs for energy and metabolism, and deficiency is uncommon in most developed countries. Prescription-strength niacin has been used to...

Read the full Niacin monograph → Herb & supplement monograph

Sour Cherry

Sour cherry (often sold as tart cherry or Montmorency cherry) is a fruit-based supplement rich in antioxidants that people use for muscle recovery, joint and gout symptoms, and sleep. Early...

Read the full Sour Cherry monograph → Herb & supplement monograph

Ribose

Interacts with 86 drugs

Ribose (D-ribose) is a simple sugar your body makes naturally and uses to build energy molecules like ATP. Some people take it for fatigue, fibromyalgia, exercise recovery, or heart conditio...

Read the full Ribose monograph → Herb & supplement monograph

Deer Velvet

Interacts with 52 drugs

Deer velvet is a traditional remedy made from the soft, growing antlers of deer or elk, and it is most often promoted for energy, athletic performance, and joint health. Good-quality human e...

Read the full Deer Velvet monograph →
Sources

Sources & How We Checked

IGF-1 Extreme's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 80 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Niacin 66 references
  1. Garg R, Malinow MR, Pettinger M, et al. Niacin treatment increases plasma homocysteine levels. Am Heart J 1999;138:1082-7.
  2. Anon. Inositol hexaniacinate. Altern Med Rev 1998;3:222-3.
  3. Knodel LC, Talbert RL. Adverse effects of hypolipidaemic drugs. Med Toxicol 1987;2:10-32. PubMed
  4. Guyton JR, Blazing MA, Hagar J, et al. Extended-release niacin vs gemfibrozil for the treatment of low levels of high-density lipoprotein cholesterol. Niaspan-Gemfibrozil Study Group. Arch Intern Med 2000;160:1177-84. PubMed
  5. Gibbons LW, Gonzalez V, Gordon N, Grundy S. The prevalence of side effects with regular and sustained-release nicotinic acid. Am J Med 1995;99:378-85. PubMed
  6. Whelan AM, Price SO, Fowler SF, Hainer BL. The effect of aspirin on niacin-induced cutaneous reactions. J Fam Pract 1992;34:165-8.
  7. Jungnickel PW, Maloley PA, Vander Tuin EL, et al. Effect of two aspirin pretreatment regimens on niacin-induced cutaneous reactions. J Gen Intern Med 1997;12:591-6. PubMed
  8. Capuzzi DM, Guyton JR, Morgan JM, et al. Efficacy and safety of an extended-release niacin (Niaspan): a long-term study. Am J Cardiol 1998;82:74-81;disc. 85U-6U. PubMed
  9. Gray DR, Morgan T, Chretien SD, Kashyap ML. Efficacy and safety of controlled-release niacin in dyslipoproteinemic veterans. Ann Intern Med 1994;121:252-8. PubMed
  10. McKenney JM, Proctor JD, Harris S, Chinchili VM. A comparison of the efficacy and toxic effects of sustained- vs immediate-release niacin in hypercholesterolemic patients. JAMA 1994;271:672-7. DOI
  11. Knopp RH, Alagona P, Davidson M, et al. Equivalent efficacy of a time-release form of niacin (Niaspan) given once-a-night versus plain niacin in the management of hyperlipidemia. Metabolism 1998;47:1097-104. PubMed
  12. Knopp RH. Clinical profiles of plain versus sustained-release niacin (Niaspan) and the physiologic rationale for nighttime dosing. Am J Cardiol 1998;82:24U-28U;discussion 39U-41U. PubMed
  13. Garg A, Grundy SM. Nicotinic acid as therapy for dyslipidemia in non-insulin-dependent diabetes mellitus. JAMA 1990;264:723-6. DOI
  14. Leighton RF, Gordon NF, Small GS, et al. Dental and gingival pain as side effects of niacin therapy. Chest 1998;114:1472-4. PubMed
  15. American Society of Health-System Pharmacists. ASHP Therapeutic Position Statement on the safe use of niacin in the management of dyslipidemias. Am J Health Syst Pharm 1997;54:2815-9. DOI
  16. Vega GL, Grundy SM. Lipoprotein responses to treatment with lovastatin, gemfibrozil, and nicotinic acid in normolipidemic patients with hypoalphalipoproteinemia. Arch Intern Med 1994;154:73-82. DOI
  17. Guyton JR, Goldberg AC, Kreisberg RA, et al. Effectiveness of once-nightly dosing of extended-release niacin alone and in combination for hypercholesterolemia. Am J Cardiol 1998;82:737-43.
  18. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
  19. Brown BG, Zhao XQ, Chait A, et al. Simvastatin and niacin, antioxidant vitamins, or the combination for the prevention of coronary disease. N Engl J Med 2001;345:1583-93. DOI
  20. Bays HE, Dujovne CA. Drug interactions of lipid-altering drugs. Drug Saf 1998;19:355-71. PubMed
  21. Rader JI, Calvert RJ, Hathcock JN. Hepatic toxicity of unmodified and time-release preparations of niacin. Am J Med 1992;92:77-81. PubMed
  22. Kahn SE, Beard JC, Schwartz MW, et al. Increased B-cell secretory capacity as mechanism for islet adaptation to nicotinic acid-induced insulin resistance. Diabetes 1989;38:562-8.
  23. Schwartz ML. Severe reversible hyperglycemia as a consequence of niacin therapy. Arch Int Med 1993;153:2050-2. DOI
  24. Raising HDL and Niacin Use. Pharmacist's Letter/Prescriber's Letter 2004;20(5):200504.
  25. McKenney J. New perspectives on the use of niacin in the treatment of lipid disorders. Arch Intern Med 2004;164:697-705. PubMed
  26. Reaven P, Witztum JL. Lovastatin, nicotinic acid and rhabdomyolysis (letter). Ann Int Med 1988;109:597-8. PubMed
  27. Ito MK. Advances in the understanding and management of dyslipidemia: using niacin-based therapies. Am J Health-Syst Pharm 2003;60(suppl 2):s15-21. PubMed
  28. Schwab RA, Bachhuber BH. Delirium and lactic acidosis caused by ethanol and niacin coingestion. Am J Emerg Med 1991;9:363-5. PubMed
  29. Product information: Niaspan. Kos Pharmaceuticals. Cranbury, NJ. 2005. Available at www.niaspan.com/professional/content/pdfs/productinfo.pdf. (Accessed 3 March 2006).
  30. Ding RW, Kolbe K, Merz B, et al. Pharmacokinetics of nicotinic acid-salicylic acid interaction. Clin Pharmacol Ther 1989;46:642-7. PubMed
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Sour Cherry 4 references
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Deer Velvet 2 references
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See these in context on the Deer Velvet monograph →

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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